Research Output 1984 2017

2017

Antioxidant capacity and superoxide dismutase activity in adrenoleukodystrophy

Turk, B. R., Theisen, B. E., Nemeth, C. L., Marx, J. S., Shi, X., Rosen, M., Jones, R. O., Moser, A. B., Watkins, P. A., Raymond, G. V., Tiffany, C. & Fatemi, A. May 1 2017 In : JAMA Neurology. 74, 5, p. 519-524 6 p.

Research output: Research - peer-reviewArticle

Adrenoleukodystrophy
Superoxide Dismutase
Antioxidants
Heterozygote
Proteins
2008
Peroxisomal Disorders
Peroxisomes
Plasmalogens
Fatty Acids
pipecolic acid
2007

Analysis of genetic interactions on a genome-wide scale in budding yeast: Diploid-based synthetic lethality analysis by microarray

Meluh, P. B., Pan, X., Yuan, D. S., Tiffany, C., Chen, O., Sookhai-Mahadeo, S., Wang, X., Peyser, B. D., Irizarry, R., Spencer, F. A. & Boeke, J. D. Dec 1 2007 Methods in Molecular Biology. Vol. 416, p. 221-247 27 p. (Methods in Molecular Biology; vol. 416)

Research output: ResearchChapter

Saccharomycetales
Microarray Analysis
Diploidy
Genome
Polymerase Chain Reaction
2005

Improved statistical analysis of budding yeast TAG microarrays revealed by defined spike-in pools

Peyser, B. D., Irizarry, R. A., Tiffany, C. W., Chen, O., Yuan, D. S., Boeke, J. D. & Spencer, F. A. 2005 In : Nucleic Acids Research. 33, 16, p. 1-5 5 p.

Research output: Research - peer-reviewArticle

Saccharomycetales
Synthetic Lethal Mutations
Yeasts
Genome
Sequence Deletion

Improved statistical analysis of budding yeast TAG microarrays revealed by defined spike-in pools.

Peyser, B. D., Irizarry, R. A., Tiffany, C. W., Chen, O., Yuan, D. S., Boeke, J. D. & Spencer, F. A. 2005 In : Nucleic Acids Research. 33, 16

Research output: Research - peer-reviewArticle

Saccharomycetales
Synthetic Lethal Mutations
Yeasts
Genome
Sequence Deletion
2002
Glutamate Carboxypeptidase II
Hydrolysis
Enzymes
N-acetyl-1-aspartylglutamic acid
Aspartic Acid
2001
Glutamate Carboxypeptidase II
Membranes
Brain
2-(phosphonomethyl)pentanedioic acid
High-Throughput Screening Assays
2000

Prostate-specific membrane antigen (PSMA) enzyme activity is elevated in prostate cancer cells

Lapidus, R. G., Tiffany, C. W., Isaacs, J. T. & Slusher, B. S. 2000 In : Prostate. 45, 4, p. 350-354 5 p.

Research output: Research - peer-reviewArticle

Prostatic Neoplasms
Enzymes
human glutamate carboxypeptidase II
Prostatic Hyperplasia
Prostate

Suramin potently inhibits the enzymatic activity of PSM

Slusher, B. S., Tiffany, C. W., Merion, A., Lapidus, R. G. & Jackson, P. F. Jun 15 2000 In : Prostate. 44, 1, p. 55-60 6 p.

Research output: Research - peer-reviewArticle

Suramin
human glutamate carboxypeptidase II
Glutamic Acid
Prostatic Neoplasms
Hormones
1999

Characterization of the enzymatic activity of PSM: Comparison with brain NAALADase

Tiffany, C. W., Lapidus, R. G., Merion, A., Calvin, D. C. & Slusher, B. S. Mar 15 1999 In : Prostate. 39, 1, p. 28-35 8 p.

Research output: Research - peer-reviewArticle

Glutamate Carboxypeptidase II
Brain
Enzymes
human glutamate carboxypeptidase II
Prostate
1997

Use of identical assay conditions for cocaine analog binding and dopamine uptake to identify potential cocaine antagonists

Slusher, B. S., Tiffany, C. W., Olkowski, J. L. & Jackson, P. F. Oct 25 1997 In : Drug and Alcohol Dependence. 48, 1, p. 43-50 8 p.

Research output: Research - peer-reviewArticle

Cocaine
Assays
Dopamine
Dopamine Plasma Membrane Transport Proteins
pharmaceutical
1993

Bridged γ-carbolines and derivatives possessing selective and combined affinity for 5-HT2 and D2 receptors

Mewshaw, R. E., Silverman, L. S., Mathew, R. M., Kaiser, C., Sherrill, R. G., Cheng, M., Tiffany, C. W., Karbon, E. W., Bailey, M. A., Borosky, S. A., Ferkany, J. W. & Abreu, M. E. 1993 In : Journal of Medicinal Chemistry. 36, 10, p. 1488-1495 8 p.

Research output: Research - peer-reviewArticle

Serotonin
Derivatives
gamma-carboline
indole
Indoles

Examination of the D2/5-HT2 affinity ratios of resolved 5,6,7,8,9,10-hexahydro-7,10-iminocyclohept[b]indoles: An enantioselective approach toward the design of potential atypical antipsychotics

Mewshaw, R. E., Abreu, M. E., Silverman, L. S., Mathew, R. M., Tiffany, C. W., Bailey, M. A., Karbon, E. W., Ferkany, J. W. & Kaiser, C. 1993 In : Journal of Medicinal Chemistry. 36, 21, p. 3073-3076 4 p.

Research output: Research - peer-reviewArticle

Indoles
Antipsychotic Agents
Serotonin
indole
gamma-carboline
1991

Erratum: N-(Fluorenyl-9-methoxy-carbonyl) amino acids, a class of antiinflammatory agents with a different mechanism of action (Proc. Natl. Acad. Sci. USA (January 1991) 88 (355-359))

Burch, R. M., Weitzberg, M., Blok, N., Muhlhauser, R., Martin, D., Farmer, S. G., Bator, J. M., Connor, J. R., Ko, C., Kuhn, W., McMillan, B. A., Raynor, M., Shearer, B. G., Tiffany, C. & Wilkins, D. E. 1991 In : Proceedings of the National Academy of Sciences of the United States of America. 88, 6, p. 2612 1 p.

Research output: Research - peer-reviewArticle

N-(Fluorenyl-9-methoxycarbonyl) amino acids, a class of antiinflammatory agents with a different mechanism of action

Burch, R. M., Weitzberg, M., Blok, N., Muhlhauser, R., Martin, D., Farmer, S. G., Bator, J. M., Connor, J. R., Ko, C., Kuhn, W., McMillan, B. A., Raynor, M., Shearer, B. G., Tiffany, C. & Wilkins, D. E. 1991 In : Proceedings of the National Academy of Sciences of the United States of America. 88, 2, p. 355-359 5 p.

Research output: Research - peer-reviewArticle

Anti-Inflammatory Agents
Amino Acids
N-(fluorenyl-9-methoxycarbonyl)leucine
Oxazolone
Dermatitis

NPC 15437 interacts with the C1 domain of protein kinase C An analysis using mutant PKC constructs

Sullivan, J. P., Connor, J. R., Tiffany, C., Shearer, B. G. & Burch, R. M. Jul 8 1991 In : FEBS Letters. 285, 1, p. 120-123 4 p.

Research output: Research - peer-reviewArticle

Protein Kinase C
NPC 15437
Enzymes
Phorbol Esters
Protein Kinases
1990

Arachidonic acid metabolism in fibroblasts from patients with peroxisomal diseases: response to interleukin 1

Tiffany, C. W., Hoefler, S., Moser, H. W. & Burch, R. M. Nov 14 1990 In : Biochimica et Biophysica Acta - Molecular Basis of Disease. 1096, 1, p. 41-46 6 p.

Research output: Research - peer-reviewArticle

Interleukin-1
Arachidonic Acid
Fibroblasts
Phospholipases A
Prostaglandin-Endoperoxide Synthases
1989

Bradykinin stimulates tumor necrosis factor and interleukin-1 release from macrophages

Tiffany, C. W. & Burch, R. M. Apr 24 1989 In : FEBS Letters. 247, 2, p. 189-192 4 p.

Research output: Research - peer-reviewArticle

Bradykinin
Interleukin-1
Tumor Necrosis Factor-alpha
Macrophages
Cytokines

Properties of acid ceramidase from human spleen

Al, B. J. M., Tiffany, C. W., Gomes de Mesquita, D. S., Moser, H. W., Tager, J. M. & Schram, A. Aug 8 1989 In : Biochimica et Biophysica Acta (BBA)/Lipids and Lipid Metabolism. 1004, 2, p. 245-251 7 p.

Research output: Research - peer-reviewArticle

Octoxynol
Spleen
human ASAH1 protein
Acid Ceramidase
Detergents

The kallikrein-kininogen-kinin system in chronic inflammation

Burch, R. M., Connor, J. R. & Tiffany, C. W. Jun 1989 In : Agents and Actions. 27, 3-4, p. 258-260 3 p.

Research output: Research - peer-reviewArticle

Kininogens
Kinins
Kallikreins
Bradykinin
Kallikrein-Kinin System
Bradykinin
Interleukin-1
Arachidonic Acid
Metabolism
Amplification
1988

Increased Levels of Ceramide in the Retina of a Patient with Farber's Disease

Zarbin, M. A., Green, W. R., Moser, A. B. & Tiffany, C. 1988 In : Archives of Ophthalmology. 106, 9, p. 1163 1 p.

Research output: Research - peer-reviewArticle

1985

Fetal cerebrohepatorenal (Zellweger) syndrome: Dysmorphic, radiologic, biochemical, and pathologic findings in four affected fetuses

Powers, J. M., Moser, H. W., Moser, A. B., Upshur, J. K., Bradford, B. F., Pai, S. G., Kohn, P. H., Frias, J. & Tiffany, C. 1985 In : Human Pathology. 16, 6, p. 610-620 11 p.

Research output: Research - peer-reviewArticle

Zellweger Syndrome
Fetus
Kidney
Patella
Fatty Acids

The prenatal diagnosis of the cerebro-hepato-renal syndrome of Zellweger

Solish, G. I., Moser, H. W., Ringer, L. D., Tiffany, C. & Schutta, E. 1985 In : Prenatal Diagnosis. 5, 1, p. 27-34 8 p.

Research output: Research - peer-reviewArticle

Zellweger Syndrome
Prenatal Diagnosis
Pregnancy
Amniotic Fluid
Fatty Acids
1984

Prolonged survival and remyelination after hematopoietic cell transplantation in the twitcher mouse

Yeager, A. M., Brennan, S., Tiffany, C., Moser, H. W. & Santos, G. W. 1984 In : Science. 225, 4666, p. 1052-1054 3 p.

Research output: Research - peer-reviewArticle

Cell Transplantation
Survival
Globoid Cell Leukodystrophy
Transplantation
Enzymes