Caren L Meyers

Associate Professor

20002019
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Fingerprint Dive into the research topics where Caren L Meyers is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

Novobiocin Medicine & Life Sciences
Enzymes Medicine & Life Sciences
Aminocoumarins Medicine & Life Sciences
Biosynthesis Chemical Compounds
Prodrugs Medicine & Life Sciences
Diphosphates Chemical Compounds
Thiamine Pyrophosphate Medicine & Life Sciences
Glyceraldehyde 3-Phosphate Medicine & Life Sciences

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Research Output 2000 2019

Enamide Prodrugs of Acetyl Phosphonate Deoxy- d -xylulose-5-phosphate Synthase Inhibitors as Potent Antibacterial Agents

Bartee, D., Sanders, S., Phillips, P. D., Harrison, M. J., Koppisch, A. T. & Meyers, C. L., Mar 8 2019, In : ACS Infectious Diseases. 5, 3, p. 406-417 12 p.

Research output: Contribution to journalArticle

Organophosphonates
Prodrugs
Anti-Bacterial Agents
Bacterial Physiological Phenomena
Thiamine Pyrophosphate

Semi-solid prodrug nanoparticles for long-acting delivery of water-soluble antiretroviral drugs within combination HIV therapies

Hobson, J. J., Al-khouja, A., Curley, P., Meyers, D. J., Flexner, C. W., Siccardi, M., Owen, A., Meyers, C. L. & Rannard, S. P., Dec 1 2019, In : Nature communications. 10, 1, 1413.

Research output: Contribution to journalArticle

human immunodeficiency virus
Prodrugs
Drug Combinations
Viruses
Nanoparticles

X-ray crystallography–based structural elucidation of enzyme-bound intermediates along the 1-deoxy-D-xylulose 5-phosphate synthase reaction coordinate

Chen, P. Y. T., DeColli, A. A., Meyers, C. L. & Drennan, C. L., Jan 1 2019, In : Journal of Biological Chemistry. 294, 33, p. 12405-12414 10 p.

Research output: Contribution to journalArticle

Decarboxylation
X-Rays
X rays
Xylulose
Glyceraldehyde 3-Phosphate

Growth medium-dependent antimicrobial activity of early stage MEP pathway inhibitors

Sanders, S., Bartee, D., Harrison, M. J., Phillips, P. D., Koppisch, A. T. & Meyers, C. L., May 1 2018, In : PLoS One. 13, 5, e0197638.

Research output: Contribution to journalArticle

Nutrients
culture media
anti-infective agents
Phosphates
phosphates

Oxidative decarboxylation of pyruvate by 1-deoxy-D-xyulose 5-phosphate synthase, a central metabolic enzyme in bacteria

DeColli, A. A., Nemeria, N. S., Majumdar, A., Gerfen, G. J., Jordan, F. & Meyers, C. L., Jan 1 2018, In : Journal of Biological Chemistry. 293, 28, p. 10857-10869 13 p.

Research output: Contribution to journalArticle

Decarboxylation
Pyruvic Acid
Bacteria
Phosphates
Thiamine Pyrophosphate