Camilo Rojas

Assistant Professor

1981 …2017
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Research Output 1981 2017

Development of a primary microglia screening assay and its use to characterize inhibition of system xc - by erastin and its analogs

Figuera-Losada, M., Thomas, A. G., Stathis, M., Stockwell, B. R., Rojas, C. & Slusher, B. S. Mar 1 2017 In : Biochemistry and Biophysics Reports. 9, p. 266-272 7 p.

Research output: Contribution to journalArticle

Microglia
Glutamic Acid
Assays
Screening
Cystine

Enhanced Brain Delivery of 2-(Phosphonomethyl)pentanedioic Acid Following Intranasal Administration of Its γ-Substituted Ester Prodrugs

Nedelcovych, M., Dash, R. P., Tenora, L., Zimmermann, S. C., Gadiano, A. J., Garrett, C., Alt, J., Hollinger, K. R., Pommier, E., Jančařík, A., Rojas, C., Thomas, A. G., Wu, Y., Wozniak, K., Majer, P., Slusher, B. S. & Rais, R. Oct 2 2017 In : Molecular Pharmaceutics. 14, 10, p. 3248-3257 10 p.

Research output: Contribution to journalArticle

Intranasal Administration
Prodrugs
Esters
Brain
Glutamate Carboxypeptidase II
Allosteric Site
Protein Transport
Binding Sites
Genotype
Proteins

Allosteric Glutaminase Inhibitors Based on a 1,4-Di(5-amino-1,3,4-thiadiazol-2-yl)butane Scaffold

Zimmermann, S. C., Wolf, E. F., Luu, A., Thomas, A. G., Stathis, M., Poore, B., Nguyen, C., Le, A., Rojas, C., Slusher, B. S. & Tsukamoto, T. May 12 2016 In : ACS Medicinal Chemistry Letters. 7, 5, p. 520-524 5 p.

Research output: Contribution to journalArticle

Glutaminase
Scaffolds
Benzeneacetamides
Thiadiazoles
Allosteric Site

Combination therapy with BPTES nanoparticles and metformin targets the metabolic heterogeneity of pancreatic cancer

Elgogary, A. , Xu, Q. , Poore, B. , Alt, J. , Zimmermann, S. C. , Zhao, L. , Fu, J. , Chen, B. , Xia, S. , Liu, Y. , Neisser, M. , Nguyen, C. , Lee, R. , Park, J. K. , Reyes, J. , Hartung, T. , Rojas, C. , Rais, R. , Tsukamoto, T. , Semenza, G. L. & 3 others Hanes, J., Slusher, B. S. & Le, A. Sep 6 2016 In : Proceedings of the National Academy of Sciences of the United States of America. 113, 36, p. E5328-E5336

Research output: Contribution to journalArticle

Glutaminase
Metformin
Pancreatic Neoplasms
Nanoparticles
Neoplasms