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  • 4 Similar Profiles
Glutamate Carboxypeptidase II Medicine & Life Sciences
Glutamic Acid Medicine & Life Sciences
Therapeutics Medicine & Life Sciences
Brain Medicine & Life Sciences
Enzymes Medicine & Life Sciences
Serine Medicine & Life Sciences
Glutaminase Medicine & Life Sciences
Assays Chemical Compounds

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Research Output 1981 2017

Development of a primary microglia screening assay and its use to characterize inhibition of system xc - by erastin and its analogs

Figuera-Losada, M., Thomas, A. G., Stathis, M., Stockwell, B. R., Rojas, C. & Slusher, B. S. Mar 1 2017 In : Biochemistry and Biophysics Reports. 9, p. 266-272 7 p.

Research output: Research - peer-reviewArticle

Glutamic Acid
Assays
Screening
erastin
Microglia

Enhanced Brain Delivery of 2-(Phosphonomethyl)pentanedioic Acid Following Intranasal Administration of Its γ-Substituted Ester Prodrugs

Nedelcovych, M., Dash, R. P., Tenora, L., Zimmermann, S. C., Gadiano, A. J., Garrett, C., Alt, J., Hollinger, K. R., Pommier, E., Jančařík, A., Rojas, C., Thomas, A. G., Wu, Y., Wozniak, K., Majer, P., Slusher, B. S. & Rais, R. Oct 2 2017 In : Molecular Pharmaceutics. 14, 10, p. 3248-3257 10 p.

Research output: Research - peer-reviewArticle

Intranasal Administration
Prodrugs
Esters
Brain
2-(phosphonomethyl)pentanedioic acid
Allosteric Site
Protein Transport
Binding Sites
Proteins
PK 11195

Allosteric Glutaminase Inhibitors Based on a 1,4-Di(5-amino-1,3,4-thiadiazol-2-yl)butane Scaffold

Zimmermann, S. C., Wolf, E. F., Luu, A., Thomas, A. G., Stathis, M., Poore, B., Nguyen, C., Le, A., Rojas, C., Slusher, B. S. & Tsukamoto, T. May 12 2016 In : ACS Medicinal Chemistry Letters. 7, 5, p. 520-524 5 p.

Research output: Research - peer-reviewArticle

Glutaminase
butane
Scaffolds
CB-839
Benzeneacetamides

Combination therapy with BPTES nanoparticles and metformin targets the metabolic heterogeneity of pancreatic cancer

Elgogary, A. , Xu, Q. , Poore, B. , Alt, J. , Zimmermann, S. C. , Zhao, L. , Fu, J. , Chen, B. , Xia, S. , Liu, Y. , Neisser, M. , Nguyen, C. , Lee, R. , Park, J. K. , Reyes, J. , Hartung, T. , Rojas, C. , Rais, R. , Tsukamoto, T. , Semenza, G. L. & 3 others Hanes, J., Slusher, B. S. & Le, A. Sep 6 2016 In : Proceedings of the National Academy of Sciences of the United States of America. 113, 36, p. E5328-E5336

Research output: Research - peer-reviewArticle

Glutaminase
Metformin
Pancreatic Neoplasms
Nanoparticles
Neoplasms