Brian O'Rourke

Professor

1984 …2018
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Cardiac Myocytes Medicine & Life Sciences
Mitochondria Medicine & Life Sciences
Muscle Cells Medicine & Life Sciences
Adenosine Triphosphate Medicine & Life Sciences
Reactive Oxygen Species Medicine & Life Sciences
Oxidation-Reduction Medicine & Life Sciences
Heart Failure Medicine & Life Sciences
Excitation Contraction Coupling Medicine & Life Sciences

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Research Output 1984 2018

Assessing spatiotemporal and functional organization of mitochondrial networks

Kurz, F. T., Aon, M. A., O’Rourke, B. & Armoundas, A. A. Jan 1 2018 Methods in Molecular Biology. Humana Press Inc., p. 383-402 20 p. (Methods in Molecular Biology; vol. 1782)

Research output: Chapter in Book/Report/Conference proceedingChapter

Cardiac Myocytes
Oxidation-Reduction
Mitochondrial Dynamics
Neurons
Mitochondrial Membrane Potential

Conservation of cardiac L-type Ca2+ channels and their regulation in Drosophila: A novel genetically-pliable channelopathic model

Limpitikul, W. B., Viswanathan, M. C., O'Rourke, B., Yue, D. T. & Cammarato, A. Jun 1 2018 In : Journal of Molecular and Cellular Cardiology. 119, p. 64-74 11 p.

Research output: Contribution to journalArticle

Diptera
Drosophila
Cardiac Myocytes
Channelopathies
Colforsin

Cardiosphere-Derived Cells Demonstrate Metabolic Flexibility That Is Influenced by Adhesion Status

Afzal, J., Chan, A., Karakas, M. F., Woldemichael, K., Vakrou, S., Guan, Y., Rathmell, J., Wahl, R., Pomper, M., Foster, D. B., Aon, M. A., Tsui, B., O'Rourke, B. & Abraham, M. R. Oct 1 2017 In : JACC: Basic to Translational Science. 2, 5, p. 543-560 18 p.

Research output: Contribution to journalArticle

Glycolysis
Cell Adhesion
Adenosine Triphosphate
Phosphorylation
Glucose

Cdon deficiency causes cardiac remodeling through hyperactivation of WNT/β-catenin signaling

Jeong, M. H., Kim, H. J., Pyun, J. H., Choi, K. S., Lee, D. I., Solhjoo, S., O'Rourke, B., Tomaselli, G. F., Jeong, D. S., Cho, H. & Kang, J. S. Feb 21 2017 In : Proceedings of the National Academy of Sciences of the United States of America. 114, 8, p. E1345-E1354

Research output: Contribution to journalArticle

beta Catenin
Connexin 43
Fibrosis
Cardiac Myocytes
Up-Regulation

Functional implications of cardiac mitochondria clustering

Kurz, F. T., Aon, M. A., O’Rourke, B. & Armoundas, A. A. May 1 2017 Advances in Experimental Medicine and Biology. Springer New York LLC, Vol. 982, (Advances in Experimental Medicine and Biology; vol. 982)

Research output: Chapter in Book/Report/Conference proceedingChapter

Mitochondria
Muscle Cells
Cluster Analysis
Reactive Oxygen Species
Cardiac Myocytes