Brian O'Rourke

Professor

1984 …2019
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Fingerprint Dive into the research topics where Brian O'Rourke is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 24 Similar Profiles
Cardiac Myocytes Medicine & Life Sciences
Mitochondria Medicine & Life Sciences
Muscle Cells Medicine & Life Sciences
Adenosine Triphosphate Medicine & Life Sciences
Reactive Oxygen Species Medicine & Life Sciences
Oxidation-Reduction Medicine & Life Sciences
Heart Failure Medicine & Life Sciences
Excitation Contraction Coupling Medicine & Life Sciences

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Research Output 1984 2019

Metformin Improves Mitochondrial Respiratory Activity through Activation of AMPK

Wang, Y., An, H., Liu, T., Qin, C., Sesaki, H., Guo, S., Radovick, S., Hussain, M., Maheshwari, A., Wondisford, F. E., O'Rourke, B. & He, L., Nov 5 2019, In : Cell Reports. 29, 6, p. 1511-1523.e5

Research output: Contribution to journalArticle

Open Access
AMP-Activated Protein Kinases
Metformin
Chemical activation
Respiration
Pharmacology

miR-181c Activates Mitochondrial Calcium Uptake by Regulating MICU1 in the Heart

Banavath, H. N., Roman, B., Mackowski, N., Biswas, D., Afzal, J., Nomura, Y., Solhjoo, S., O'Rourke, B., Kohr, M., Murphy, E., Steenbergen, C. & Das, S., Dec 17 2019, In : Journal of the American Heart Association. 8, 24, p. e012919

Research output: Contribution to journalArticle

Open Access
Calcium
Reperfusion Injury
Mitochondria
Muscle Cells
Small Interfering RNA

Precisely Control Mitochondria with Light to Manipulate Cell Fate Decision

Ernst, P., Xu, N., Qu, J., Chen, H., Goldberg, M. S., Darley-Usmar, V., Zhang, J. J., O'Rourke, B., Liu, X. & Zhou, L., Aug 20 2019, In : Biophysical journal. 117, 4, p. 631-645 15 p.

Research output: Contribution to journalArticle

Optogenetics
Mitochondria
Light
Mitochondrial Membranes
Lighting

Single-channel properties of the ROMK-pore-forming subunit of the mitochondrial ATP-sensitive potassium channel

Laskowski, M., Augustynek, B., Bednarczyk, P., Żochowska, M., Kalisz, J., O’rourke, B., Szewczyk, A. & Kulawiak, B., Nov 1 2019, In : International journal of molecular sciences. 20, 21, 5323.

Research output: Contribution to journalArticle

Open Access
KATP Channels
adenosine triphosphate
Adenosinetriphosphate
Potassium
porosity