Brian O'Rourke

Professor

1984 …2019
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Fingerprint Dive into the research topics where Brian O'Rourke is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 11 Similar Profiles
Cardiac Myocytes Medicine & Life Sciences
Mitochondria Medicine & Life Sciences
Muscle Cells Medicine & Life Sciences
Adenosine Triphosphate Medicine & Life Sciences
Reactive Oxygen Species Medicine & Life Sciences
Oxidation-Reduction Medicine & Life Sciences
Heart Failure Medicine & Life Sciences
Excitation Contraction Coupling Medicine & Life Sciences

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Research Output 1984 2019

Allele-specific differences in transcriptome, miRNome, and mitochondrial function in two hypertrophic cardiomyopathy mouse models

Vakrou, S., Fukunaga, R., Foster, D. B., Sorensen, L., Liu, Y., Guan, Y., Woldemichael, K., Pineda-Reyes, R., Liu, T., Tardiff, J. C., Leinwand, L. A., Tocchetti, C. G., Abraham, T. P., O'Rourke, B., Aon, M. A. & Abraham, M. R., Mar 22 2018, In : JCI insight. 3, 6

Research output: Contribution to journalArticle

Open Access
Hypertrophic Cardiomyopathy
Transcriptome
Alleles
Mutation
Antioxidants

Assessing spatiotemporal and functional organization of mitochondrial networks

Kurz, F. T., Aon, M. A., O'Rourke, B. & Armoundas, A. A., Jan 1 2018, Methods in Molecular Biology. Humana Press Inc., p. 383-402 20 p. (Methods in Molecular Biology; vol. 1782).

Research output: Chapter in Book/Report/Conference proceedingChapter

Cardiac Myocytes
Oxidation-Reduction
Mitochondrial Dynamics
Neurons
Mitochondrial Membrane Potential

Conservation of cardiac L-type Ca2+ channels and their regulation in Drosophila: A novel genetically-pliable channelopathic model

Limpitikul, W. B., Viswanathan, M. C., O'Rourke, B., Yue, D. T. & Cammarato, A. R., Jun 1 2018, In : Journal of Molecular and Cellular Cardiology. 119, p. 64-74 11 p.

Research output: Contribution to journalArticle

Diptera
Drosophila
Cardiac Myocytes
Channelopathies
Colforsin

Mitochondrial ROS Drive Sudden Cardiac Death and Chronic Proteome Remodeling in Heart Failure

Dey, S., DeMazumder, D., Sidor, A., Foster, D. B. & O'Rourke, B., Jul 20 2018, In : Circulation Research. 123, 3, p. 356-371 16 p.

Research output: Contribution to journalArticle

Sudden Cardiac Death
Proteome
Reactive Oxygen Species
Heart Failure
Cardiac Arrhythmias