Brady Maher

Associate Professor

20052018
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Research Output 2005 2018

Developmental and genetic regulation of the human cortex transcriptome illuminate schizophrenia pathogenesis

The BrainSeq Consortium, Aug 1 2018, In : Nature Neuroscience. 21, 8, p. 1117-1125 9 p.

Research output: Contribution to journalArticle

Medical Genetics
Transcriptome
Schizophrenia
Quantitative Trait Loci
RNA Sequence Analysis

The intellectual disability and schizophrenia associated transcription factor TCF4 is regulated by neuronal activity and protein kinase A

Sepp, M., Vihma, H., Nurm, K., Urb, M., Page, S. C., Roots, K., Hark, A., Maher, B., Pruunsild, P. & Timmusk, T., Oct 25 2017, In : Journal of Neuroscience. 37, 43, p. 10516-10527 12 p.

Research output: Contribution to journalArticle

Cyclic AMP-Dependent Protein Kinases
Intellectual Disability
Schizophrenia
Transcription Factors
Neurons

The schizophrenia- and autism-associated gene, transcription factor 4 regulates the columnar distribution of layer 2/3 prefrontal pyramidal neurons in an activity-dependent manner

Page, S. C., Hamersky, G. R., Gallo, R. A., Rannals, M. D., Calcaterra, N. E., Campbell, M. N., Mayfield, B., Briley, A., Phan, B. N., Jaffe, A. & Maher, B., Mar 14 2017, (Accepted/In press) In : Molecular Psychiatry.

Research output: Contribution to journalArticle

Pyramidal Cells
Autistic Disorder
Schizophrenia
Transcription Factors
Psychiatry

A human-specific AS3MT isoform and BORCS7 are molecular risk factors in the 10q24.32 schizophrenia-associated locus

Li, M., Jaffe, A., Straub, R. E., Tao, R., Shin, J. H., Wang, Y., Chen, Q., Li, C., Jia, Y., Ohi, K., Maher, B., Brandon, N. J., Cross, A., Chenoweth, J. G., Hoeppner, D. J., Wei, H., Hyde, T., McKay, R., Kleinman, J. & Weinberger, D., Jun 1 2016, In : Nature Medicine. 22, 6, p. 649-656 8 p.

Research output: Contribution to journalArticle

Schizophrenia
Protein Isoforms
Genes
Polymorphism
Minisatellite Repeats

Brain-Region-Specific Organoids Using Mini-bioreactors for Modeling ZIKV Exposure

Qian, X., Nguyen, H. N., Song, M. M., Hadiono, C., Ogden, S. C., Hammack, C., Yao, B., Hamersky, G. R., Jacob, F., Zhong, C., Yoon, K. J., Jeang, W., Lin, L., Li, Y., Thakor, J., Berg, D. A., Zhang, C., Kang, E., Chickering, M., Nauen, D. & 10 othersHo, C. Y., Wen, Z., Christian, K. M., Shi, P. Y., Maher, B., Wu, H., Jin, P., Tang, H., Song, H. & Ming, G. L., May 19 2016, In : Cell. 165, 5, p. 1238-1254 17 p.

Research output: Contribution to journalArticle

Organoids
Bioreactors
Viruses
Brain
Human Development