Bo Xiao

Research Associate

19982018
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Research Output 1998 2018

Distinct roles of Rheb and Raptor in activating mTOR complex 1 for the self-renewal of hematopoietic stem cells

Peng, H., Kasada, A., Ueno, M., Hoshii, T., Tadokoro, Y., Nomura, N., Ito, C., Takase, Y., Vu, H. T., Kobayashi, M., Xiao, B., Worley, P. F. & Hirao, A., Jan 1 2018, In : Biochemical and Biophysical Research Communications. 495, 1, p. 1129-1135 7 p.

Research output: Contribution to journalArticle

Raptors
Hematopoietic Stem Cell Transplantation
Hematopoietic Stem Cells
Inbred C57BL Mouse
Cultured Cells

MTORC1 loss impairs epidermal adhesion via TGF-β/Rho kinase activation

Asrani, K., Sood, A., Torres, A., Georgess, D., Phatak, P., Kaur, H., Dubin, A., Talbot, C. C., Elhelu, L., Ewald, A. J., Xiao, B., Worley, P. & Lotan, T. L., Nov 1 2017, In : Journal of Clinical Investigation. 127, 11, p. 4001-4017 17 p.

Research output: Contribution to journalArticle

rho-Associated Kinases
Transforming Growth Factor beta
Epidermis
Cell Adhesion
mechanistic target of rapamycin complex 1

Orai1-Mediated Antimicrobial Secretion from Pancreatic Acini Shapes the Gut Microbiome and Regulates Gut Innate Immunity

Ahuja, M., Schwartz, D. M., Tandon, M., Son, A., Zeng, M., Swaim, W., Eckhaus, M., Hoffman, V., Cui, Y., Xiao, B., Worley, P. F. & Muallem, S., Mar 7 2017, In : Cell Metabolism. 25, 3, p. 635-646 12 p.

Research output: Contribution to journalArticle

Innate Immunity
Dysbiosis
Intestinal Diseases
Weight Gain
Immune System

Targeting human Mas-related G protein-coupled receptor X1 to inhibit persistent pain

Li, Z. , Tseng, P. Y. , Tiwari, V. , Xu, Q. , He, S. Q. , Wang, Y. , Zheng, Q. , Han, L. , Wu, Z. , Blobaum, A. L. , Cui, Y. , Tiwari, V. , Sun, S. , Cheng, Y. , Huang-Lionnet, J. H. Y. , Geng, Y. , Xiao, B. , Peng, J. , Hopkins, C. , Raja, S. N. & 2 others Guan, Y. & Dong, X., Mar 7 2017, In : Proceedings of the National Academy of Sciences of the United States of America. 114, 10, p. E1996-E2005

Research output: Contribution to journalArticle

G-Protein-Coupled Receptors
Pain
Nociceptors
Aptitude
Peripheral Nervous System

Protein kinase C epsilon activity in the nucleus accumbens and central nucleus of the amygdala mediates binge alcohol consumption

Cozzoli, D. K., Courson, J., Rostock, C., Campbell, R. R., Wroten, M. G., McGregor, H., Caruana, A. L., Miller, B. W., Hu, J. H., Zhang, P. W., Xiao, B., Worley, P. F., Crabbe, J. C., Finn, D. A. & Szumlinski, K. K., Mar 15 2016, In : Biological Psychiatry. 79, 6, p. 443-451 9 p.

Research output: Contribution to journalArticle

Protein Kinase C-epsilon
Binge Drinking
Nucleus Accumbens
Alcohol Drinking
Alcohols