Research output per year
Research output per year
- 1 - 50 out of 51 results
Search results
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2024
Imaging spatiotemporal translation regulation in vivo
Blake, L. A., De La Cruz, A. & Wu, B., Feb 15 2024, In: Seminars in Cell and Developmental Biology. 154, p. 155-164 10 p.Research output: Contribution to journal › Review article › peer-review
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2023
Adipokine C1q/Tumor Necrosis Factor- Related Protein 3 (CTRP3) Attenuates Intestinal Inflammation Via Sirtuin 1/NF-κB Signaling
Yu, H., Zhang, Z., Li, G., Feng, Y., Xian, L., Bakhsh, F., Xu, D., Xu, C., Vong, T., Wu, B., Selaru, F. M., Wan, F., Donowitz, M. & Wong, G. W., Jan 2023, In: CMGH. 15, 4, p. 1000-1015 16 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Bidirectional Transcription at the PPP2R2B Gene Locus in Spinocerebellar Ataxia Type 12
Zhou, C., Liu, H. B., Jahanbakhsh, F., Deng, L., Wu, B., Ying, M., Margolis, R. L. & Li, P. P., Dec 2023, In: Movement Disorders. 38, 12, p. 2230-2240 11 p.Research output: Contribution to journal › Article › peer-review
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Bursting translation on single mRNAs in live cells
Livingston, N. M., Kwon, J., Valera, O., Saba, J. A., Sinha, N. K., Reddy, P., Nelson, B., Wolfe, C., Ha, T., Green, R., Liu, J. & Wu, B., Jul 6 2023, In: Molecular cell. 83, 13, p. 2276-2289.e11Research output: Contribution to journal › Article › peer-review
Open Access -
Single-molecule imaging reveals distinct elongation and frameshifting dynamics between frames of expanded RNA repeats in C9ORF72-ALS/FTD
Latallo, M. J., Wang, S., Dong, D., Nelson, B., Livingston, N. M., Wu, R., Zhao, N., Stasevich, T. J., Bassik, M. C., Sun, S. & Wu, B., Dec 2023, In: Nature communications. 14, 1, 5581.Research output: Contribution to journal › Article › peer-review
Open Access -
2022
Dynamin is primed at endocytic sites for ultrafast endocytosis
Imoto, Y., Raychaudhuri, S., Ma, Y., Fenske, P., Sandoval, E., Itoh, K., Blumrich, E. M., Matsubayashi, H. T., Mamer, L., Zarebidaki, F., Söhl-Kielczynski, B., Trimbuch, T., Nayak, S., Iwasa, J. H., Liu, J., Wu, B., Ha, T., Inoue, T., Jorgensen, E. M., Cousin, M. A., & 2 others, Sep 7 2022, In: Neuron. 110, 17, p. 2815-2835.e13Research output: Contribution to journal › Article › peer-review
Open Access -
Next generation single-molecule techniques: Imaging, labeling, and manipulation in vitro and in cellulo
Ha, T., Kaiser, C., Myong, S., Wu, B. & Xiao, J., Jan 20 2022, In: Molecular cell. 82, 2, p. 304-314 11 p.Research output: Contribution to journal › Review article › peer-review
Open Access -
2021
Cas9 deactivation with photocleavable guide RNAs
Zou, R. S., Liu, Y., Wu, B. & Ha, T., Apr 1 2021, In: Molecular cell. 81, 7, p. 1553-1565.e8Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Epigenetically regulated digital signaling defines epithelial innate immunity at the tissue level
Clark, H. R., McKenney, C., Livingston, N. M., Gershman, A., Sajjan, S., Chan, I. S., Ewald, A. J., Timp, W., Wu, B., Singh, A. & Regot, S., Dec 1 2021, In: Nature communications. 12, 1, 1836.Research output: Contribution to journal › Article › peer-review
Open Access -
Live-cell imaging reveals kinetic determinants of quality control triggered by ribosome stalling
Goldman, D. H., Livingston, N. M., Movsik, J., Wu, B. & Green, R., Apr 15 2021, In: Molecular cell. 81, 8, p. 1830-1840.e8Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Nuclear export and translation of circular repeat-containing intronic RNA in C9ORF72-ALS/FTD
Wang, S., Latallo, M. J., Zhang, Z., Huang, B., Bobrovnikov, D. G., Dong, D., Livingston, N. M., Tjoeng, W., Hayes, L. R., Rothstein, J. D., Ostrow, L. W., Wu, B. & Sun, S., Dec 1 2021, In: Nature communications. 12, 1, 4908.Research output: Contribution to journal › Article › peer-review
Open Access -
2020
Very fast CRISPR on demand
Liu, Y., Zou, R. S., He, S., Nihongaki, Y., Li, X., Razavi, S., Wu, B. & Ha, T., Jun 12 2020, In: Science. 368, 6496, p. 1265-1269 5 p.Research output: Contribution to journal › Article › peer-review
Open Access29 Scopus citations -
Visualizing the translation and packaging of HIV-1 full-length RNA
Chen, J., Liu, Y., Wu, B., Nikolaitchik, O. A., Mohan, P. R., Chen, J., Pathak, V. K. & Hu, W. S., Mar 17 2020, In: Proceedings of the National Academy of Sciences of the United States of America. 117, 11, p. 6145-6155 11 p.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
2019
Fluorescence imaging methods to investigate translation in single cells
Biswas, J., Liu, Y., Singer, R. H. & Wu, B., 2019, In: Cold Spring Harbor Perspectives in Biology. 11, 4, a032722.Research output: Contribution to journal › Article › peer-review
Open Access13 Scopus citations -
One Message, Many Translations: Heterogeneity Revealed with Multicolor Imaging
Blake, L. A. & Wu, B., Jul 11 2019, In: Molecular cell. 75, 1, p. 3-4 2 p.Research output: Contribution to journal › Short survey › peer-review
Open Access2 Scopus citations -
Retargeting of macroH2A following mitosis to cytogenetic-scale heterochromatic domains
Sato, H., Wu, B., Delahaye, F., Singer, R. H. & Greally, J. M., Jun 3 2019, In: Journal of Cell Biology. 218, 6, p. 1810-1823 14 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Translation imaging of single mRNAs in established cell lines and primary cultured neurons
Latallo, M. J., Livingston, N. M. & Wu, B., Jun 1 2019, In: Methods. 162-163, p. 12-22 11 p.Research output: Contribution to journal › Review article › peer-review
4 Scopus citations -
2018
Imaging mRNA in Vivo, from Birth to Death
Tutucci, E., Livingston, N. M., Singer, R. H. & Wu, B., May 20 2018, In: Annual Review of Biophysics. 47, p. 85-106 22 p.Research output: Contribution to journal › Review article › peer-review
Open Access49 Scopus citations -
Spatial Organization of Single mRNPs at Different Stages of the Gene Expression Pathway
Adivarahan, S., Livingston, N., Nicholson, B., Rahman, S., Wu, B., Rissland, O. S. & Zenklusen, D., Nov 15 2018, In: Molecular cell. 72, 4, p. 727-738.e5Research output: Contribution to journal › Article › peer-review
Open Access46 Scopus citations -
2017
2,4 DNP improves motor function, preserves medium spiny neuronal identity, and reduces oxidative stress in a mouse model of Huntington's disease
Wu, B., Jiang, M., Peng, Q., Li, G., Hou, Z., Milne, G. L., Mori, S., Alonso, R., Geisler, J. G. & Duan, W., Jul 1 2017, In: Experimental Neurology. 293, p. 83-90 8 p.Research output: Contribution to journal › Article › peer-review
Open Access13 Scopus citations -
Rac3 regulates breast cancer invasion and metastasis by controlling adhesion and matrix degradation
Donnelly, S. K., Cabrera, R., Mao, S. P. H., Christin, J. R., Wu, B., Guo, W., Bravo-Cordero, J. J., Condeelis, J. S., Segall, J. E. & Hodgson, L., 2017, In: Journal of Cell Biology. 216, 12, p. 4331-4349 19 p.Research output: Contribution to journal › Article › peer-review
Open Access28 Scopus citations -
2016
Characterization of behavioral, neuropathological, brain metabolic and key molecular changes in zQ175 knock-in mouse model of huntington's disease
Peng, Q., Wu, B., Jiang, M., Jin, J., Hou, Z., Zheng, J., Zhang, J. & Duan, W., Feb 1 2016, In: PloS one. 11, 2, e0148839.Research output: Contribution to journal › Article › peer-review
Open Access22 Scopus citations -
Glutamate-induced RNA localization and translation in neurons
Yoon, Y. J., Wu, B., Buxbaum, A. R., Das, S., Tsai, A., English, B. P., Grimm, J. B., Lavis, L. D. & Singer, R. H., Nov 1 2016, In: Proceedings of the National Academy of Sciences of the United States of America. 113, 44, p. E6877-E6886Research output: Contribution to journal › Article › peer-review
Open Access74 Scopus citations -
Optical tools to study the isoform-specific roles of small GTPases in immune cells
Miskolci, V., Wu, B., Moshfegh, Y., Cox, D. & Hodgson, L., Apr 15 2016, In: Journal of Immunology. 196, 8, p. 3479-3493 15 p.Research output: Contribution to journal › Article › peer-review
Open Access11 Scopus citations -
Translation dynamics of single mRNAs in live cells and neurons
Wu, B., Eliscovich, C., Yoon, Y. J. & Singer, R. H., Jun 17 2016, In: Science. 352, 6292, p. 1430-1435 6 p.Research output: Contribution to journal › Article › peer-review
229 Scopus citations -
2015
Assembly and molecular architecture of the phosphoinositide 3-kinase p85α homodimer
LoPiccolo, J., Kim, S. J., Shi, Y., Wu, B., Wu, H., Chait, B. T., Singer, R. H., Sali, A., Brenowitz, M., Bresnick, A. R. & Backer, J. M., Dec 18 2015, In: Journal of Biological Chemistry. 290, 51, p. 30390-30405 16 p.Research output: Contribution to journal › Article › peer-review
Open Access13 Scopus citations -
Quantifying Protein-mRNA Interactions in Single Live Cells
Wu, B., Buxbaum, A. R., Katz, Z. B., Yoon, Y. J. & Singer, R. H., Jul 3 2015, In: Cell. 162, 1, p. 211-220 10 p.Research output: Contribution to journal › Article › peer-review
Open Access56 Scopus citations -
Synonymous modification results in highfidelity gene expression of repetitive protein and nucleotide sequences
Wu, B., Miskolci, V., Sato, H., Tutucci, E., Kenworthy, C. A., Donnelly, S. K., Yoon, Y. J., Cox, D., Singer, R. H. & Hodgson, L., 2015, In: Genes and Development. 29, 8, p. 876-886 11 p.Research output: Contribution to journal › Article › peer-review
Open Access39 Scopus citations -
2014
Background free imaging of single mRNAs in live cells using split fluorescent proteins
Wu, B., Chen, J. & Singer, R. H., Jan 9 2014, In: Scientific reports. 4, 3615.Research output: Contribution to journal › Article › peer-review
Open Access48 Scopus citations -
Single β-actin mRNA detection in neurons reveals a mechanism for regulating its translatability
Buxbaum, A. R., Wu, B. & Singer, R. H., 2014, In: Science. 343, 6169, p. 419-422 4 p.Research output: Contribution to journal › Article › peer-review
162 Scopus citations -
2013
Time-integrated fluorescence cumulant analysis and its application in living cells
Wu, B., Singer, R. H. & Mueller, J. D., 2013, Fluorescence Fluctuation Spectroscopy (FFS), Part A. Academic Press Inc., p. 99-119 21 p. (Methods in Enzymology; vol. 518).Research output: Chapter in Book/Report/Conference proceeding › Chapter
5 Scopus citations -
2012
Fluorescence fluctuation spectroscopy enables quantitative imaging of single mRNAs in living cells
Wu, B., Chao, J. A. & Singer, R. H., Jun 20 2012, In: Biophysical journal. 102, 12, p. 2936-2944 9 p.Research output: Contribution to journal › Article › peer-review
Open Access106 Scopus citations -
Regulation of local expression of cell adhesion and motility-related mRNAs in breast cancer cells by IMP1/ZBP1
Gu, W., Katz, Z., Wu, B., Park, H. Y., Li, D., Lin, S., Wells, A. L. & Singer, R. H., Jan 1 2012, In: Journal of cell science. 125, 1, p. 81-91 11 p.Research output: Contribution to journal › Article › peer-review
Open Access52 Scopus citations -
β-actin mRNA compartmentalization enhances focal adhesion stability and directs cell migration
Katz, Z. B., Wells, A. L., Park, H. Y., Wu, B., Shenoy, S. M. & Singer, R. H., Sep 1 2012, In: Genes and Development. 26, 17, p. 1885-1890 6 p.Research output: Contribution to journal › Article › peer-review
Open Access74 Scopus citations -
2011
Determining antibody stoichiometry using time-integrated fluorescence cumulant analysis
Skinner, J. P., Wu, B., Mueller, J. D. & Tetin, S. Y., Feb 10 2011, In: Journal of Physical Chemistry B. 115, 5, p. 1131-1138 8 p.Research output: Contribution to journal › Article › peer-review
3 Scopus citations -
Modern fluorescent proteins and imaging technologies to study gene expression, nuclear localization, and dynamics
Wu, B., Piatkevich, K. D., Lionnet, T., Singer, R. H. & Verkhusha, V. V., Jun 2011, In: Current Opinion in Cell Biology. 23, 3, p. 310-317 8 p.Research output: Contribution to journal › Review article › peer-review
Open Access107 Scopus citations -
Real-time observation of transcription initiation and elongation on an endogenous yeast gene
Larson, D. R., Zenklusen, D., Wu, B., Chao, J. A. & Singer, R. H., Apr 22 2011, In: Science. 332, 6028, p. 475-478 4 p.Research output: Contribution to journal › Article › peer-review
Open Access362 Scopus citations -
2010
Heterospecies partition analysis reveals binding curve and stoichiometry of protein interactions in living cells
Wu, B., Chen, Y. & Müller, J. D., Mar 2 2010, In: Proceedings of the National Academy of Sciences of the United States of America. 107, 9, p. 4117-4122 6 p.Research output: Contribution to journal › Article › peer-review
23 Scopus citations -
Monomeric red fluorescent proteins with a large Stokes shift
Piatkevich, K. D., Hulit, J., Subach, O. M., Wu, B., Abdulla, A., Segall, J. E. & Verkhusha, V. V., Mar 23 2010, In: Proceedings of the National Academy of Sciences of the United States of America. 107, 12, p. 5369-5374 6 p.Research output: Contribution to journal › Article › peer-review
108 Scopus citations -
Nuclear physics: Quantitative single-cell approaches to nuclear organization and gene expression
Lionnet, T., Wu, B., Grünwald, D., Singer, R. H. & Larson, D. R., 2010, In: Cold Spring Harbor symposia on quantitative biology. 75, p. 113-126 14 p.Research output: Contribution to journal › Article › peer-review
Open Access14 Scopus citations -
Observing Protein Interactions and Their Stoichiometry in Living Cells by Brightness Analysis of Fluorescence Fluctuation Experiments
Chen, Y., Johnson, J., Macdonald, P., Wu, B. & Mueller, J. D., Jan 2010, Methods in Enzymology. Academic Press Inc., p. 345-363 19 p. (Methods in Enzymology; vol. 472).Research output: Chapter in Book/Report/Conference proceeding › Chapter
34 Scopus citations -
2009
Fluorescence fluctuation spectroscopy of mCherry in living cells
Wu, B., Chen, Y. & Müller, J. D., 2009, In: Biophysical journal. 96, 6, p. 2391-2404 14 p.Research output: Contribution to journal › Article › peer-review
Open Access48 Scopus citations -
Fluorescence fluctuation spectroscopy on viral-like particles reveals variable Gag stoichiometry
Chen, Y., Wu, B., Musier-Forsyth, K., Mansky, L. M. & Mueller, J. D., 2009, In: Biophysical journal. 96, 5, p. 1961-1969 9 p.Research output: Contribution to journal › Article › peer-review
Open Access49 Scopus citations -
2008
Fluorescence correlation spectroscopy of finite-sized particles
Wu, B., Chen, Y. & Müller, J. D., Apr 2008, In: Biophysical journal. 94, 7, p. 2800-2808 9 p.Research output: Contribution to journal › Article › peer-review
Open Access31 Scopus citations -
2006
Cumulant analysis in two-color fluorescence fluctuation spectroscopy
Wu, B., Chen, Y. & Müller, J. D., 2006, Proceedings of SPIE - The International Society for Optical Engineering. 60890J. (Proceedings of SPIE - The International Society for Optical Engineering; vol. 6089).Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
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Dual-color time-integrated fluorescence cumulant analysis
Wu, B., Chen, Y. & Müller, J. D., Oct 2006, In: Biophysical journal. 91, 7, p. 2687-2698 12 p.Research output: Contribution to journal › Article › peer-review
Open Access25 Scopus citations -
2005
Dual-color photon-counting histogram
Chen, Y., Tekmen, M., Hillesheim, L., Skinner, J., Wu, B. & Müller, J. D., Mar 2005, In: Biophysical journal. 88, 3, p. 2177-2192 16 p.Research output: Contribution to journal › Article › peer-review
Open Access46 Scopus citations -
Time-integrated fluorescence cumulant analysis in fluorescence fluctuation spectroscopy
Wu, B. & Müller, J. D., Oct 2005, In: Biophysical journal. 89, 4, p. 2721-2735 15 p.Research output: Contribution to journal › Article › peer-review
Open Access57 Scopus citations -
2003
Mean-field approach to a probabilistic model in information retrieval
Wu, B., Wong, K. Y. M. & Bodoff, D., Jan 1 2003, Advances in Neural Information Processing Systems 15 - Proceedings of the 2002 Conference, NIPS 2002. Neural information processing systems foundation, (Advances in Neural Information Processing Systems).Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
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Relevance data for language models using maximum likelihood
Bodoff, D., Wu, B. & Wong, K. Y. M., Sep 2003, In: Journal of the American Society for Information Science and Technology. 54, 11, p. 1050-1061 12 p.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations