Research output per year
Research output per year
- 1 - 50 out of 195 results
Search results
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2024
Intrinsic and Microenvironmental Drivers of Glioblastoma Invasion
De Fazio, E., Pittarello, M., Gans, A., Ghosh, B., Slika, H., Alimonti, P. & Tyler, B., Mar 2024, In: International journal of molecular sciences. 25, 5, 2563.Research output: Contribution to journal › Review article › peer-review
Open Access -
2023
A Highly Translatable Dual-arm Local Delivery Strategy To Achieve Widespread Therapeutic Coverage in Healthy and Tumor-bearing Brain Tissues
Negron, K., Kwak, G., Wang, H., Li, H., Huang, Y. T., Chen, S. W., Tyler, B., Eberhart, C. G., Hanes, J. & Suk, J. S., Mar 15 2023, In: Small. 19, 11, 2207278.Research output: Contribution to journal › Article › peer-review
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Dendrimer Technology in Glioma: Functional Design and Potential Applications
Gaitsch, H., Hersh, A. M., Alomari, S. & Tyler, B. M., Feb 2023, In: Cancers. 15, 4, 1075.Research output: Contribution to journal › Review article › peer-review
Open Access -
Disruption of the Blood-Spinal Cord Barrier using Low-Intensity Focused Ultrasound in a Rat Model
Bhimreddy, M., Routkevitch, D., Hersh, A. M., Mohammadabadi, A., Menta, A. K., Jiang, K., Weber-Levine, C., Davidar, A. D., Punnoose, J., Kempski Leadingham, K. M., Doloff, J. C., Tyler, B., Theodore, N. & Manbachi, A., Mar 10 2023, In: Journal of visualized experiments : JoVE. 193Research output: Contribution to journal › Article › peer-review
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Long-Acting Opioid Analgesics for Acute Pain: Pharmacokinetic Evidence Reviewed
Tyler, B. M. & Guarnieri, M., Jun 2023, In: Veterinary Sciences. 10, 6, 372.Research output: Contribution to journal › Review article › peer-review
Open Access -
Preclinical Models and Technologies in Glioblastoma Research: Evolution, Current State, and Future Avenues
Slika, H., Karimov, Z., Alimonti, P., Abou-Mrad, T., De Fazio, E., Alomari, S. & Tyler, B., Nov 2023, In: International journal of molecular sciences. 24, 22, 16316.Research output: Contribution to journal › Review article › peer-review
Open Access -
Self-assembling paclitaxel-mediated stimulation of tumor-associated macrophages for postoperative treatment of glioblastoma
Wang, F., Huang, Q., Su, H., Sun, M., Wang, Z., Chen, Z., Zheng, M., Chakroun, R. W., Monroe, M. K., Chen, D., Wang, Z., Gorelick, N., Serra, R., Wang, H., Guan, Y., Suk, J. S., Tyler, B., Brem, H., Hanes, J. & Cui, H., 2023, In: Proceedings of the National Academy of Sciences of the United States of America. 120, 118, e2204621120.Research output: Contribution to journal › Article › peer-review
Open Access -
Sonodynamic Therapy for the Treatment of Glioblastoma Multiforme in a Mouse Model Using a Portable Benchtop Focused Ultrasound System
Mess, G., Anderson, T., Kapoor, S., Thombre, R., Liang, R., Derin, E., Kempskileadingham, K. M., Yadav, S. K., Tyler, B. & Manbachi, A., Feb 2023, In: Journal of Visualized Experiments. 2023, 192, e65114.Research output: Contribution to journal › Article › peer-review
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The Neurodevelopmental and Molecular Landscape of Medulloblastoma Subgroups: Current Targets and the Potential for Combined Therapies
Slika, H., Alimonti, P., Raj, D., Caraway, C., Alomari, S., Jackson, E. M. & Tyler, B., Aug 2023, In: Cancers. 15, 15, 3889.Research output: Contribution to journal › Review article › peer-review
Open Access -
2022
Applications of Focused Ultrasound for the Treatment of Glioblastoma: A New Frontier
Hersh, A. M., Bhimreddy, M., Weber-Levine, C., Jiang, K., Alomari, S., Theodore, N., Manbachi, A. & Tyler, B. M., Oct 2022, In: Cancers. 14, 19, 4920.Research output: Contribution to journal › Review article › peer-review
Open Access -
Combined intracranial Acriflavine, temozolomide and radiation extends survival in a rat glioma model
Serra, R., Mangraviti, A., Gorelick, N. L., Shapira-Furman, T., Alomari, S., Cecia, A., Darjee, N., Brem, H., Rottenberg, Y., Domb, A. J. & Tyler, B., Jan 2022, In: European Journal of Pharmaceutics and Biopharmaceutics. 170, p. 179-186 8 p.Research output: Contribution to journal › Article › peer-review
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Crossing the Blood-Brain Barrier: Advances in Nanoparticle Technology for Drug Delivery in Neuro-Oncology
Hersh, A. M., Alomari, S. & Tyler, B. M., Apr 1 2022, In: International journal of molecular sciences. 23, 8, 4153.Research output: Contribution to journal › Article › peer-review
Open Access -
DESIGN AND DEVELOPMENT OF SYSTEM COMPONENTS FOR THERAPEUTIC ULTRASOUND DEVICES: ENHANCING FOCUSED ULTRASOUND TREATMENTS USING CONES WITH CLINICAL AND ERGONOMIC CONSIDERATIONS
Thombre, R., Mess, G., Curry, E., Mejia, R., Liang, R., Aghabaglou, F., Kerensky, M., Abramson, H., VanSickle, R., Tyler, B., Theodore, N. & Manbachi, A., 2022, Proceedings of the 2022 Design of Medical Devices Conference, DMD 2022. American Society of Mechanical Engineers, V001T05A001. (Proceedings of the 2022 Design of Medical Devices Conference, DMD 2022).Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
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DESIGNING A MURINE MODEL OF HUMAN GLIOBLASTOMA BRAIN TUMOR: DEVELOPMENT OF A PLATFORM FOR VALIDATION USING ULTRASOUND ELASTOGRAPHY
Mess, G., Thombre, R., Kerensky, M., Curry, E., Abhabaglou, F., Alomari, S., Brem, H., Theodore, N., Tyler, B. & Manbachi, A., 2022, Proceedings of the 2022 Design of Medical Devices Conference, DMD 2022. American Society of Mechanical Engineers, V001T08A001. (Proceedings of the 2022 Design of Medical Devices Conference, DMD 2022).Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
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Impact of international research fellows in neurosurgery: results from a single academic center
Yang, W., Rincon-Torroella, J., Feghali, J., Khalafallah, A. M., Ishida, W., Perdomo-Pantoja, A., Quinones-Hinojosa, A., Lim, M., Gallia, G. L., Riggins, G. J., Anderson, W. S., Lo, S., Rigamonti, D., Tamargo, R. J., Witham, T. F., Bydon, A., Cohen, A. R., Jallo, G. I., Latremoliere, A., Luciano, M. G., & 8 others, Jan 2022, In: Journal of neurosurgery. 136, 1, p. 295-305 11 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Implementation of Minimally Invasive Brain Tumor Resection in Rodents for High Viability Tissue Collection
Alomari, S., Kedda, J., Malla, A. P., Pacis, V., Anastasiadis, P., Xu, S., McFarland, E., Sukhon, L., Gallo, B., Rincon-Torroella, J., Ben-Shalom, N., Ames, H. M., Brem, H., Woodworth, G. F. & Tyler, B., May 2022, In: Journal of Visualized Experiments. 2022, 183, e64048.Research output: Contribution to journal › Article › peer-review
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Metformin and Cancer, an Ambiguanidous Relationship
Skuli, S. J., Alomari, S., Gaitsch, H., Bakayoko, AI., Skuli, N. & Tyler, B. M., May 1 2022, In: Pharmaceuticals. 15, 5, 626.Research output: Contribution to journal › Review article › peer-review
Open Access -
Molecular Pathways and Genomic Landscape of Glioblastoma Stem Cells: Opportunities for Targeted Therapy
Hersh, A. M., Gaitsch, H., Alomari, S., Lubelski, D. & Tyler, B. M., Aug 2022, In: Cancers. 14, 15, 3743.Research output: Contribution to journal › Review article › peer-review
Open Access -
Polymeric Nanoparticles in Brain Cancer Therapy: A Review of Current Approaches
Caraway, C. A., Gaitsch, H., Wicks, E. E., Kalluri, A., Kunadi, N. & Tyler, B. M., Jul 2022, In: Polymers. 14, 14, 2963.Research output: Contribution to journal › Review article › peer-review
Open Access -
Synergy between glutamate modulation and anti-programmed cell death protein 1 immunotherapy for glioblastoma
Medikonda, R., Choi, J., Pant, A., Saleh, L., Routkevitch, D., Tong, L., Belcaid, Z., Kim, Y. H., Jackson, C. M., Jackson, C., Mathios, D., Xia, Y., Shah, P. P., Patel, K., Kim, T., Srivastava, S., Huq, S., Ehresman, J., Pennington, Z., Tyler, B., & 2 others, Feb 2022, In: Journal of neurosurgery. 136, 2, p. 379-388 10 p.Research output: Contribution to journal › Article › peer-review
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Towards standardization of the parameters for opening the blood–brain barrier with focused ultrasound to treat glioblastoma multiforme: A systematic review of the devices, animal models, and therapeutic compounds used in rodent tumor models
Thombre, R., Mess, G., Kempski Leadingham, K. M., Kapoor, S., Hersh, A., Acord, M., Kaovasia, T., Theodore, N., Tyler, B. & Manbachi, A., 2022, In: Frontiers in Oncology. 12, 1072780.Research output: Contribution to journal › Review article › peer-review
Open Access -
Translational Regulation by hnRNP H/F Is Essential for the Proliferation and Survival of Glioblastoma
Le Bras, M., Gorelick, N., Pautet, S., Tyler, B., Manenti, S., Skuli, N., Millevoi, S. & Cammas, A., Mar 1 2022, In: Cancers. 14, 5, 1283.Research output: Contribution to journal › Article › peer-review
Open Access -
Ultrasound monitoring of microcirculation: An original study from the laboratory bench to the clinic
Aghabaglou, F., Ainechi, A., Abramson, H., Curry, E., Kaovasia, T. P., Kamal, S., Acord, M., Mahapatra, S., Pustavoitau, A., Smith, B., Azadi, J., Son, J. K., Suk, I., Theodore, N., Tyler, B. M. & Manbachi, A., Oct 2022, In: MICROCIRCULATION. 29, 6-7, e12770.Research output: Contribution to journal › Article › peer-review
Open Access -
2021
Automatic detection of cotton balls during brain surgery: Where deep learning meets ultrasound imaging to tackle foreign objects
Mahapatra, S., Balamurugan, M., Chung, K., Kuppoor, V., Curry, E., Aghabaglau, F., Kaovasia, T. P., Acord, M., Ainechi, A., Kim, J. H., Tshey, Y., Ghinda, C. D., Son, J. K., Pustavoitau, A., Tyler, B., Robinson, S. D., Theodore, N., Brem, H., Huang, J. & Manbachi, A., 2021, Medical Imaging 2021: Ultrasonic Imaging and Tomography. Byram, B. C. & Ruiter, N. V. (eds.). SPIE, 116021C. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 11602).Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
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Buprenorphine implants: a model for expedited development and approval of new drugs
Guarnieri, M., Kedda, J. & Tyler, B., 2021, In: Current Medical Research and Opinion. 37, 1, p. 83-88 6 p.Research output: Contribution to journal › Review article › peer-review
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Captopril inhibits Matrix Metalloproteinase-2 and extends survival as a temozolomide adjuvant in an intracranial gliosarcoma model
Pinheiro, L., Perdomo-Pantoja, A., Casaos, J., Huq, S., Paldor, I., Vigilar, V., Mangraviti, A., Wang, Y., Witham, T. F., Brem, H. & Tyler, B., Aug 2021, In: Clinical Neurology and Neurosurgery. 207, 106771.Research output: Contribution to journal › Article › peer-review
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Design and fabrication of a focused ultrasound device for minimallyinvasive neurosurgery: Reporting a second, miniaturized and mrcompatible prototype with steering capabilities
Acord, M., Kaovasia, T. P., Gamo, N., Xiong, T., Curry, E., Aghabaglou, F., Morrison, K., Tyler, B., Luciano, M. & Manbachi, A., 2021, Proceedings of the 2021 Design of Medical Devices Conference, DMD 2021. American Society of Mechanical Engineers, V001T13A009. (Proceedings of the 2021 Design of Medical Devices Conference, DMD 2021).Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
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Design of an ultrasound probe holder to minimize motion artifact during sonography
Mahapatra, S., Kaovasia, T. P., Ainechi, S., Ainechi, A., Acord, M., Curry, E. J., Aghabaglou, F., Tyler, B., Theodore, N. & Manbachi, A., 2021, Proceedings of the 2021 Design of Medical Devices Conference, DMD 2021. American Society of Mechanical Engineers, V001T01A003. (Proceedings of the 2021 Design of Medical Devices Conference, DMD 2021).Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
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Development of a Smart Hospital Assistant: Integrating artificial intelligence and a voice-user interface for improved surgical outcomes
Kim, J. H., Um, R., Liu, J., Patel, J., Curry, E., Aghabaglou, F., Mahapatra, S., Ainechi, A., Tsehay, Y., Ehresman, J., Hwang, B., Tyler, B., Iyer, R., Theodore, N. & Manbachi, A., 2021, Medical Imaging 2021: Imaging Informatics for Healthcare, Research, and Applications. Deserno, T. M. & Park, B. J. (eds.). SPIE, 116010U. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 11601).Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
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Disulfiram and copper combination therapy targets NPL4, cancer stem cells and extends survival in a medulloblastoma model
Serra, R., Zhao, T., Huq, S., Gorelick, N. L., Casaos, J., Cecia, A., Mangraviti, A., Eberhart, C., Bai, R., Olivi, A., Brem, H., Jackson, E. M. & Tyler, B., Nov 2021, In: PloS one. 16, 11 November, e0251957.Research output: Contribution to journal › Article › peer-review
Open Access -
Drug repurposing for glioblastoma and current advances in drug delivery—A comprehensive review of the literature
Alomari, S., Tyler, B., Zhang, I., Hernandez, A., Kraft, C. Y., Raj, D. & Kedda, J., Dec 2021, In: Biomolecules. 11, 12, 1870.Research output: Contribution to journal › Review article › peer-review
Open Access -
High-Intensity Focused Ultrasound: A Review of Mechanisms and Clinical Applications
Bachu, V. S., Kedda, J., Suk, I., Green, J. J. & Tyler, B., Sep 2021, In: Annals of biomedical engineering. 49, 9, p. 1975-1991 17 p.Research output: Contribution to journal › Review article › peer-review
Open Access -
Neurosurgical Implant-Based Strategy for Brain Cancer Therapy
Casaos, J., Gorelick, N. & Tyler, B., 2021, Neuromethods. Humana Press Inc., p. 225-244 20 p. (Neuromethods; vol. 163).Research output: Chapter in Book/Report/Conference proceeding › Chapter
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Pectic Galactan Polysaccharide-Based Gene Delivery System for Targeting Neuroinflammation
Buaron, N., Mangraviti, A., Volpin, F., Liu, A., Pedone, M., Sankey, E., Aranovich, D., Adar, I., Rodriguez, F. J., Nyska, A., Goldbart, R., Traitel, T., Brem, H., Tyler, B. & Kost, J., Oct 26 2021, In: Advanced Functional Materials. 31, 44, 2100643.Research output: Contribution to journal › Article › peer-review
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Pharmacological strategies for improving the prognosis of glioblastoma
Raj, D., Agrawal, P., Gaitsch, H., Wicks, E. & Tyler, B., 2021, In: Expert opinion on pharmacotherapy. 22, 15, p. 2019-2031 13 p.Research output: Contribution to journal › Review article › peer-review
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Preclinical efficacy of ribavirin in SHH and group 3 medulloblastoma
Huq, S., Kannapadi, N. V., Casaos, J., Lott, T., Felder, R., Serra, R., Gorelick, N. L., Ruiz-Cardozo, M. A., Ding, A. S., Cecia, A., Medikonda, R., Ehresman, J., Brem, H., Skuli, N. & Tyler, B. M., Apr 2021, In: Journal of Neurosurgery: Pediatrics. 27, 4, p. 482-488 7 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Targeting of cyclin-dependent kinases in atypical teratoid rhabdoid tumors with multikinase inhibitor TG02
Ding, A. S., Huq, S., Casaos, J., Raj, D., Morales, M., Zhao, T., Kim, T., Srivastava, S., Pant, A., Serra, R., Gorelick, N. L., Brem, H. & Tyler, B., Dec 2021, In: Journal of Neurosurgery: Pediatrics. 28, 6, p. 734-743 10 p.Research output: Contribution to journal › Article › peer-review
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2020
Dendrimer size effects on the selective brain tumor targeting in orthotopic tumor models upon systemic administration
Liaw, K., Zhang, F., Mangraviti, A., Kannan, S., Tyler, B. & Kannan, R. M., May 1 2020, In: Bioengineering and Translational Medicine. 5, 2, e10160.Research output: Contribution to journal › Article › peer-review
Open Access12 Scopus citations -
Evaluating the effects of cerebrospinal fluid protein content on the performance of differential pressure valves and antisiphon devices using a novel benchtop shunting model
Gorelick, N. L., Serra, R., Iyer, R., Um, R., Grewal, A., Monroe, A., Antoine, H., Beharry, K., Cecia, A., Kroll, F., Ishida, W., Perdomo-Pantoja, A., Xu, R., Loth, F., Ye, X., Suk, I., Tyler, B., Bayston, R. & Luciano, M. G., Nov 1 2020, In: Neurosurgery. 87, 5, p. 1046-1054 9 p.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Intraoperative Laser Speckle Contrast Imaging For Real-Time Visualization of Cerebral Blood Flow in Cerebrovascular Surgery: Results From Pre-Clinical Studies
Mangraviti, A., Volpin, F., Cha, J., Cunningham, S. I., Raje, K., Brooke, M. J., Brem, H., Olivi, A., Huang, J., Tyler, B. M. & Rege, A., Dec 1 2020, In: Scientific reports. 10, 1, 7614.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Intraoperative ultrasound to monitor spinal cord blood flow after spinal cord injury
Manbachi, A., Kambhampati, S., Ainechi, A., Mahapatra, S., Belzberg, M., Ying, G., Chai, R., Zhang, Y. S., Gorelick, N., Pennington, Z., Westbroek, E., Jiang, B., Hwang, B., Benassi, T., Coles, G., Tyler, B., Suk, I., Yazdi, Y. & Theodore, N., 2020, Medical Imaging 2020: Biomedical Applications in Molecular, Structural, and Functional Imaging. Krol, A. & Gimi, B. S. (eds.). SPIE, 113170B. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 11317).Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
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Minimally invasive therapeutic ultrasound: Ultrasound-guided ultrasound ablation in neuro-oncology
Belzberg, M., Mahapatra, S., Perdomo‐Pantoja, A., Chavez, F., Morrison, K., Xiong, K. T., Gamo, N., Restaino, S., Thakor, N., Yazdi, Y., Iyer, R., Tyler, B., Theodore, N., Luciano, M. G., Brem, H., Groves, M., Cohen, A. R. & Manbachi, A., Dec 2020, In: Ultrasonics. 108, 106210.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Minimizing cotton retention in neurosurgical procedures: Which imaging modality can help?
Bechtold, R., Tselepidakis, N., Garlow, B., Glaister, S., Zhu, W., Liu, R., Szewc, A., Tandon, A., Buono, Z., Pitingolo, J., Madalo, C., Ferrara, I., Shale, C., Benassi, T., Belzberg, M., Gorelick, N., Hwang, B., Molina, C. A., Coles, G., Tyler, B., & 4 others, 2020, Medical Imaging 2020: Biomedical Applications in Molecular, Structural, and Functional Imaging. Krol, A. & Gimi, B. S. (eds.). SPIE, 1131704. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 11317).Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
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Nonviral polymeric nanoparticles for gene therapy in pediatric CNS malignancies
Choi, J., Rui, Y., Kim, J., Gorelick, N., Wilson, D. R., Kozielski, K., Mangraviti, A., Sankey, E., Brem, H., Tyler, B., Green, J. J. & Jackson, E. M., Jan 2020, In: Nanomedicine: Nanotechnology, Biology, and Medicine. 23, 102115.Research output: Contribution to journal › Article › peer-review
Open Access12 Scopus citations -
Novel therapeutics for brain tumors: current practice and future prospects
El Demerdash, N., Kedda, J., Ram, N., Brem, H. & Tyler, B., Jan 2 2020, In: Expert Opinion on Drug Delivery. 17, 1, p. 9-21 13 p.Research output: Contribution to journal › Review article › peer-review
2 Scopus citations -
Repurposing the FDA-approved antiviral drug ribavirin as targeted therapy for nasopharyngeal carcinoma
Huq, S., Casaos, J., Serra, R., Peters, M., Xia, Y., Ding, A. S., Ehresman, J., Kedda, J. N., Morales, M., Gorelick, N. L., Zhao, T., Ishida, W., Perdomo-Pantoja, A., Cecia, A., Ji, C., Suk, I., Sidransky, D., Brait, M., Brem, H., Skuli, N., & 1 others, Sep 1 2020, In: Molecular cancer therapeutics. 19, 9, p. 1797-1808 12 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
2019
A miniature multi-contrast microscope for functional imaging in freely behaving animals
Senarathna, J., Yu, H., Deng, C., Zou, A. L., Issa, J. B., Hadjiabadi, D. H., Gil, S., Wang, Q., Tyler, B. M., Thakor, N. V. & Pathak, A. P., Dec 1 2019, In: Nature communications. 10, 1, 99.Research output: Contribution to journal › Article › peer-review
Open Access13 Scopus citations -
Biodegradable wafers releasing Temozolomide and Carmustine for the treatment of brain cancer
Shapira-Furman, T., Serra, R., Gorelick, N., Doglioli, M., Tagliaferri, V., Cecia, A., Peters, M., Kumar, A., Rottenberg, Y., Langer, R., Brem, H., Tyler, B. & Domb, A. J., Feb 10 2019, In: Journal of Controlled Release. 295, p. 93-101 9 p.Research output: Contribution to journal › Article › peer-review
22 Scopus citations -
Design considerations for a miniature multicontrast neuroimager
Senarathna, J., Wang, Q., Tyler, B., Thakor, N. & Pathak, A., 2019, Clinical and Translational Neurophotonics 2019. Madsen, S. J., Yang, V. X. D. & Thakor, N. V. (eds.). SPIE, 108640P. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 10864).Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
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Drug-Impregnated Polymer Delivery
Serra, R., Casaos, J., Tyler, B. & Brem, H., Jun 25 2019, Nervous System Drug Delivery: Principles and Practice. Elsevier, p. 275-296 22 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter