Beth L Laube

Professor Emeritus

1978 …2020

Research output per year

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Research Output

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Acute and chronic in vivo effects of exposure to nicotine and propylene glycol from an E-cigarette on mucociliary clearance in a murine model

Laube, B. L., Afshar-Mohajer, N., Koehler, K. A., Chen, G., Lazarus, P., Collaco, M. & McGrath-Morrow, S. A., Apr 16 2017, In : Inhalation Toxicology. 29, 5, p. 197-205 9 p.

Research output: Contribution to journalArticle

Acute exposure to acid fog: Effects on mucociliary clearance

Laube, B. L., Bowes, S. M., Links, J. M., Thomas, K. K. & Frank, R., 1993, In : American Review of Respiratory Disease. 147, 5, p. 1105-1111 7 p.

Research output: Contribution to journalArticle

Acute exposure to acid fog: Influence of breathing pattern on effective dose

Bowes, S. M., Francis, M., Laube, B. L. & Frank, R., Feb 1 1995, In : American Industrial Hygiene Association Journal. 56, 2, p. 143-150 8 p.

Research output: Contribution to journalArticle

Aerosol deposition in 3D models of the upper airways and trachea of rhesus macaques

Kesavan, J. S., Alstadt, V. J. & Laube, B. L., 2020, (Accepted/In press) In : Aerosol Science and Technology.

Research output: Contribution to journalArticle

Aerosol deposition in human airways: a regulated method of aerosol generation and delivery

Laube, B. L., Swift, D. L. & Adams, G. K., Jan 1 1981, In : American Review of Respiratory Disease. 123, 4 II, 1 p.

Research output: Contribution to journalArticle

Aerosolized medications for gene and peptide therapy

Laube, B. L., Jun 1 2015, In : Respiratory care. 60, 6, p. 806-821 16 p.

Research output: Contribution to journalArticle

Albuterol Improves Impaired Mucociliary Clearance After Lung Transplantation

Laube, B. L., Karmazyn, Y. J., Orens, J. B. & Mogayzel, P. J., Feb 1 2007, In : Journal of Heart and Lung Transplantation. 26, 2, p. 138-144 7 p.

Research output: Contribution to journalArticle

Allergen challenge and deposition of nedocromil sodium in asthma

Laube, B. L., Lin, T. C., Valleteau, A., Dalby, R. N., Diemer, F. B. & Togias, A. G., Dec 1 2002, In : Journal of Aerosol Medicine: Deposition, Clearance, and Effects in the Lung. 15, 4, p. 415-425 11 p.

Research output: Contribution to journalArticle

Analysis of refractory period after exercise and eucapnic voluntary hyperventilation challenge

Rosenthal, R. R., Laube, B. L., Hood, D. B. & Norman, P. S., Jan 1 1990, In : American Review of Respiratory Disease. 141, 2 I, p. 368-372 5 p.

Research output: Contribution to journalArticle

A pilot study examining the relationship between stress and serum cortisol concentrations in women with asthma

Laube, B. L., Curbow, B. A., Costello, R. W. & Fitzgerald, S. T., Oct 2002, In : Respiratory Medicine. 96, 10, p. 823-828 6 p.

Research output: Contribution to journalArticle

A Pilot Study to Examine the Effect of Chronic Treatment with Immunosuppressive Drugs on Mucociliary Clearance in a Vagotomized Murine Model

Bhashyam, A. R., Mogayzel, P. J., McGrath-Morrow, S., Neptune, E., Malinina, A., Fox, J. & Laube, B. L., Sep 20 2012, In : PloS one. 7, 9, e45312.

Research output: Contribution to journalArticle

Changes in mucociliary clearance over time in children with cystic fibrosis

Laube, B. L., Carson, K. A., Evans, C. M., Richardson, V. L., Sharpless, G., Zeitlin, P. L. & Mogayzel, P. J., Sep 1 2020, In : Pediatric pulmonology. 55, 9, p. 2307-2314 8 p.

Research output: Contribution to journalArticle

Cholinergic response to histamine challenge

Rosenthal, R. R., Bleeker, E. R., Laube, B., Norman, P. S. & Permutt, S., Jan 1 1978, In : Unknown Journal. 61, 3, 1 p.

Research output: Contribution to journalArticle

Chronic inhalation of nebulized levalbuterol does not increase mucociliary clearance in healthy subjects

Cleary, J. C., Karmazyn, Y., Mogayzel, P. J. & Laube, B. L., Feb 1 2008, In : Pulmonary Pharmacology and Therapeutics. 21, 1, p. 105-111 7 p.

Research output: Contribution to journalArticle

Comparison of nasal deposition and clearance of aerosol generated by a nebulizer and an aqueous spray pump

Suman, J. D., Laube, B. L. & Dalby, R., Nov 11 1999, In : Pharmaceutical Research. 16, 10, p. 1648-1652 5 p.

Research output: Contribution to journalArticle

Demonstrating bioequivalence of locally acting orally inhaled drug products (OIPs): Workshop summary report

Adams, W. P., Ahrens, R. C., Chen, M. L., Christopher, D., Chowdhury, B. A., Conner, D. P., Dalby, R., Fitzgerald, K., Hendeles, L., Hickey, A. J., Hochhaus, G., Laube, B. L., Lucas, P., Lee, S. L., Lyapustina, S., Li, B., O'Connor, D., Parikh, N., Parkins, D. A., Peri, P. & 10 others, Pitcairn, G. R., Riebe, M., Roy, P., Shah, T., Singh, G. J. P., Sharp, S. S., Suman, J. D., Weda, M., Woodcock, J. & Yu, L., Feb 1 2010, In : Journal of aerosol medicine and pulmonary drug delivery. 23, 1, p. 1-29 29 p.

Research output: Contribution to journalArticle

Deposition and expression of aerosolized rAAV vectors in the lungs of Rhesus macaques

Beck, S. E., Laube, B. L., Barberena, C. I., Fischer, A. C., Adams, R. J., Chesnut, K., Flotte, T. R. & Guggino, W. B., Oct 1 2002, In : Molecular Therapy. 6, 4, p. 546-554 9 p.

Research output: Contribution to journalArticle

Deposition of albuterol aerosol generated by pneumatic nebulizer in the Sophia Anatomical Infant Nose-Throat (SAINT) model

Laube, B. L., Sharpless, G., Shermer, C., Nasir, O., Sullivan, V. & Powell, K., Aug 1 2010, In : Pharmaceutical Research. 27, 8, p. 1722-1729 8 p.

Research output: Contribution to journalArticle

Deposition of dry powder generated by solovent in Sophia Anatomical Infant Nose-Throat (SAINT) model

Laube, B. L., Sharpless, G., Shermer, C., Sullivan, V. & Powell, K., May 1 2012, In : Aerosol Science and Technology. 46, 5, p. 514-520 7 p.

Research output: Contribution to journalArticle

Early pulmonary response to allergen is attenuated during acute emotional stress in females with asthma

Laube, B. L., Curbow, B. A., Fitzgerald, S. T. & Spratt, K., Oct 1 2003, In : European Respiratory Journal. 22, 4, p. 613-618 6 p.

Research output: Contribution to journalArticle

Open Access

Editorial: Standards for lung imaging techniques.

Laube, B. L., Corcoran, T. E., Devadason, S. G., Dolovich, M. B., Fleming, J. & Newman, S., Dec 2012, In : Journal of Aerosol Medicine and Pulmonary Drug Delivery. 25 Suppl 1

Research output: Contribution to journalArticle

Effect of environmental antigen on cholinergic hyperreactivity

Rosenthal, R. R., Bleecker, E. R. & Laube, B., Jan 1 1978, In : American Review of Respiratory Disease. 117, 4 II, 1 p.

Research output: Contribution to journalArticle

Effect of environmental antigen on cholinergic hyperreactivity.

Rosenthal, R. R., Bleecker, E. R., Laube, B., Norman, P. S. & Permutt, S., Feb 1979, In : CHEST. 75, 2 Suppl, p. 228-229 2 p.

Research output: Contribution to journalArticle

Effect of ivacaftor on mucociliary clearance and clinical outcomes in cystic fibrosis patients with G551D-CFTR

Donaldson, S. H., Laube, B. L., Corcoran, T. E., Bhambhvani, P., Zeman, K., Ceppe, A., Zeitlin, P. L., Mogayzel, P. J., Boyle, M. P., Locke, L. W., Myerburg, M. M., Pilewski, J. M., Flanagan, B., Rowe, S. M. & Bennett, W. D., Dec 20 2018, In : JCI insight. 3, 24

Research output: Contribution to journalArticle

Effect of rhDNase on airflow obstruction and mucociliary clearance in cystic fibrosis

Laube, B. L., Auci, R. M., Shields, D. E., Christiansen, D. H., Lucas, M. K., Fuchs, H. J. & Rosenstein, B. J., Jan 1 1996, In : American journal of respiratory and critical care medicine. 153, 2, p. 752-760 9 p.

Research output: Contribution to journalArticle

ERS technical standard on bronchial challenge testing: pathophysiology and methodology of indirect airway challenge testing

American Thoracic Society (ATS)/European Respiratory Society (ERS) Bronchoprovocation Testing Task Force, Nov 1 2018, In : The European respiratory journal. 52, 5

Research output: Contribution to journalArticle

ERS technical standard on bronchial challenge testing: General considerations and performance of methacholine challenge tests

Coates, A. L., Wanger, J., Cockcroft, D. W., Culver, B. H., Carlsen, K. H., Diamant, Z., Gauvreau, G., Hall, G. L., Hallstrand, T. S., Horvath, I., De Jongh, F. H. C., Joos, G., Kaminsky, D. A., Laube, B. L., Leuppi, J. D. & Sterk, P. J., May 1 2017, In : European Respiratory Journal. 49, 5, 1601526.

Research output: Contribution to journalArticle

Gene therapy in cystic fibrosis

Flotte, T. R. & Laube, B. L., 2001, In : CHEST. 120, 3 SUPPL., p. 124S-131S

Research output: Contribution to journalArticle

Homogeneity of Aerosol Deposition and Mucociliary Clearance are Improved Following Ivacaftor Treatment in Cystic Fibrosis

Bennett, W. D., Zeman, K. L., Laube, B. L., Wu, J., Sharpless, G., Mogayzel, P. & Donaldson, S. H., Aug 1 2018, In : Journal of Aerosol Medicine and Pulmonary Drug Delivery. 31, 4, p. 204-211 8 p.

Research output: Contribution to journalArticle

Homogeneity of bronchopulmonary distribution of 99mTc aerosol in normal subjects and in cystic fibrosis patients

Laube, B. L., Links, J. M., LaFrance, N. D., Wagner, H. N. & Rosenstein, B. J., Jan 1 1989, In : CHEST. 95, 4, p. 822-830 9 p.

Research output: Contribution to journalArticle

Hypertonic saline has a prolonged effect on mucociliary clearance in adults with cystic fibrosis

Trimble, A. T., Whitney Brown, A., Laube, B. L., Lechtzin, N., Zeman, K. L., Wu, J., Ceppe, A., Waltz, D., Bennett, W. D. & Donaldson, S. H., Sep 2018, In : Journal of Cystic Fibrosis. 17, 5, p. 650-656 7 p.

Research output: Contribution to journalArticle

IL-12 overexpression in mice as a model for Sjögren lung disease

McGrath-Morrow, S., Laube, B., Tzou, S. C., Cho, C., Cleary, J., Kimura, H., Rose, N. R. & Caturegli, P., Oct 9 2006, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 291, 4, p. L837-L846

Research output: Contribution to journalArticle

Inhibitory effects of DSG on methacholine challenge

Rosenthal, R. R., Laube, B. & Hood, D., Jan 1 1982, In : American Review of Respiratory Disease. 125, 4 II, 1 p.

Research output: Contribution to journalArticle

Intranasal Deposition of Accuspray™ Aerosol in Anatomically Correct Models of 2-, 5-, and 12-Year-Old Children

Laube, B. L., Sharpless, G., Vikani, A. R., Harrand, V., Zinreich, S. J., Sedberry, K., Knaus, D., Barry, J. & Papania, M., Oct 1 2015, In : Journal of aerosol medicine and pulmonary drug delivery. 28, 5, p. 320-333 14 p.

Research output: Contribution to journalArticle

Measurement of aerosol deposition in CF

Laube, B. L., Oct 1 1998, In : Pediatric pulmonology. 26, 3 SUPPL. 17, p. 181-182 2 p.

Research output: Contribution to journalArticle

Mucociliary clearance as an outcome measure for cystic fibrosis clinical research

Donaldson, S. H., Corcoran, T. E., Laube, B. L. & Bennett, W. D., Aug 1 2007, In : Proceedings of the American Thoracic Society. 4, 4, p. 399-405 7 p.

Research output: Contribution to journalArticle

Mucus removal is impaired in children with cystic fibrosis who have been infected by pseudomonas aeruginosa

Laube, B. L., Sharpless, G., Benson, J., Carson, K. A. & Mogayzel, P. J., Apr 2014, In : Journal of Pediatrics. 164, 4, p. 839-845 7 p.

Research output: Contribution to journalArticle

Multisite comparison of mucociliary and cough clearance measures using standardized methods

Bennett, W. D., Laube, B. L., Corcoran, T., Zeman, K., Sharpless, G., Thomas, K., Wu, J., Mogayzel, P. J., Pilewski, J. & Donaldson, S., Jun 1 2013, In : Journal of aerosol medicine and pulmonary drug delivery. 26, 3, p. 157-164 8 p.

Research output: Contribution to journalArticle

Positive expiratory pressure changes aerosol distribution in patients with cystic fibrosis

Laube, B. L., Geller, D. E., Lin, T. C., Dalby, R. N., Diener-West, M. & Zeitlin, P. L., Nov 2005, In : Respiratory care. 50, 11, p. 1438-1444 7 p.

Research output: Contribution to journalArticle

Potent bronchoprotective effect of deep inspiration and its absence in asthma

Kapsali, T., Permutt, S., Laube, B., Scichilone, N. & Togias, A., 2000, In : Journal of applied physiology. 89, 2, p. 711-720 10 p.

Research output: Contribution to journalArticle

Predicting in vivo lung deposition of cromolyn sodium from in vitro estimates

Laube, B. L., Jashnani, R. & Dalby, R. N., Jul 1 1998, In : Journal of Aerosol Medicine: Deposition, Clearance, and Effects in the Lung. 11, SUPPL. 1, p. S35-S42

Research output: Contribution to journalArticle

Preliminary Study of the Efficacy of Insulin Aerosol Delivered by Oral Inhalation in Diabetic Patients

Laube, B. L., Georgopoulos, A. & Adams, G. K., Apr 28 1993, In : JAMA: The Journal of the American Medical Association. 269, 16, p. 2106-2109 4 p.

Research output: Contribution to journalArticle

Pulmonary delivery of an aerosolized recombinant human butyrylcholinesterase pretreatment protects against aerosolized paraoxon in macaques

Rosenberg, Y. J., Laube, B., Mao, L., Jiang, X., Hernandez-Abanto, S., Lee, K. D. & Adams, R., Mar 25 2013, In : Chemico-Biological Interactions. 203, 1, p. 167-171 5 p.

Research output: Contribution to journalArticle

Radioaerosol assessment of lung improvement in cystic fibrosis patients treated for acute pulmonary exacerbations

Laube, B. L., Chang, D. Y., Blask, A. N. & Rosenstein, B. J., Jan 1 1992, In : CHEST. 101, 5, p. 1302-1308 7 p.

Research output: Contribution to journalArticle