Fingerprint Fingerprint is based on mining the text of the person's scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

  • 3 Similar Profiles
Genes Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Medullary Thyroid cancer Medicine & Life Sciences
Growth Medicine & Life Sciences
Calcitonin Medicine & Life Sciences
DNA Medicine & Life Sciences
Cell Line Medicine & Life Sciences
Small Cell Lung Carcinoma Medicine & Life Sciences

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Research Output 1980 2016

Long-Term ERK Inhibition in KRAS-Mutant Pancreatic Cancer Is Associated with MYC Degradation and Senescence-like Growth Suppression

Hayes, T. K. , Neel, N. F. , Hu, C. , Gautam, P. , Chenard, M. , Long, B. , Aziz, M. , Kassner, M. , Bryant, K. L. , Pierobon, M. , Marayati, R. , Kher, S. , George, S. D. , Xu, M. , Wang-Gillam, A. , Samatar, A. A. , Maitra, A. , Wennerberg, K. , Petricoin, E. F. , Yin, H. H. & 4 others Nelkin, B., Cox, A. D., Yeh, J. J. & Der, C. J. Jan 11 2016 In : Cancer Cell. 29, 1, p. 75-89 15 p.

Research output: Research - peer-reviewArticle

Phosphatidylinositol 3-Kinase
Pancreatic Neoplasms
Cell Line
Growth
Mitogen-Activated Protein Kinase Kinases

A phase I trial of vertical inhibition of IGF signalling using cixutumumab, an anti-IGF-1R antibody, and selumetinib, an MEK 1/2 inhibitor, in advanced solid tumours

Wilky, B. A., Rudek, M. A., Ahmed, S., Laheru, D. A., Cosgrove, D., Donehower, R. C., Nelkin, B., Ball, D., Doyle, L. A., Chen, H., Ye, X., Bigley, G., Womack, C. & Azad, N. S. Jan 6 2015 In : British Journal of Cancer. 112, 1, p. 24-31 8 p.

Research output: Research - peer-reviewArticle

Mitogen-Activated Protein Kinase Kinases
Antibodies
Neoplasms
anti-IGF-1R antibody A12
AZD 6244

Combined inhibition of cyclin-dependent kinases (dinaciclib) and AKT(MK-2206) blocks pancreatic tumor growth and metastases in patient-derived xenograft models

Hu, C., Dadon, T., Chenna, V., Yabuuchi, S., Bannerji, R., Booher, R., Strack, P., Azad, N., Nelkin, B. D. & Maitra, A. Jul 1 2015 In : Molecular Cancer Therapeutics. 14, 7, p. 1532-1539 8 p.

Research output: Research - peer-reviewArticle

Cyclin-Dependent Kinases
Pancreatic Neoplasms
Heterografts
Neoplasm Metastasis
Growth

Trametinib with and without pazopanib has potent preclinical activity in thyroid cancer

Ball, D. W., Jin, N., Xue, P., Bhan, S., Ahmed, S. R., Rosen, D. M., Schayowit Z, A., Clark, D. P. & Nelkin, B. D. Nov 1 2015 In : Oncology Reports. 34, 5, p. 2319-2324 6 p.

Research output: Research - peer-reviewArticle

Thyroid Neoplasms
pazopanib
trametinib
MAP Kinase Signaling System
Clinical Trials

Small-molecule screening of PC3 prostate cancer cells identifies tilorone dihydrochloride to selectively inhibit cell growth based on cyclin-dependent kinase 5 expression

Wissing, M. D., Dadon, T., Kim, E., Piontek, K. B., Shim, J. S., Kaelber, N. S., Liu, J. O., Kachhap, S. K. & Nelkin, B. D. 2014 In : Oncology Reports. 32, 1, p. 419-424 6 p.

Research output: Research - peer-reviewArticle

Tilorone
Cyclin-Dependent Kinase 5
Prostatic Neoplasms
Growth
Therapeutics