Barry D Nelkin

Professor

1980 …2017
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Research Output 1980 2017

Overall survival analysis of EXAM, a phase III trial of cabozantinib in patients with radiographically progressive medullary thyroid carcinoma

Schlumberger, M., Elisei, R., Müller, S., Schöffski, P., Brose, M., Shah, M., Licitra, L., Krajewska, J., Kreissl, M. C., Niederle, B., Cohen, E. E. W., Wirth, L., Ali, H., Clary, D. O., Yaron, Y., Mangeshkar, M., Ball, D., Nelkin, B. & Sherman, S., Jan 1 2017, In : Annals of Oncology. 28, 11, p. 2813-2819 7 p.

Research output: Contribution to journalArticle

Survival Analysis
Placebos
Survival
Confidence Intervals
Disease-Free Survival

Recent advances in the biology and therapy of medullary thyroid carcinoma

Nelkin, B. Jan 1 2017 In : F1000Research. 6, 2184

Research output: Contribution to journalReview article

Therapeutics
Developmental Biology
Neural Crest
Medullary Thyroid cancer
Thyroid Neoplasms

Long-Term ERK Inhibition in KRAS-Mutant Pancreatic Cancer Is Associated with MYC Degradation and Senescence-like Growth Suppression

Hayes, T. K. , Neel, N. F. , Hu, C. , Gautam, P. , Chenard, M. , Long, B. , Aziz, M. , Kassner, M. , Bryant, K. L. , Pierobon, M. , Marayati, R. , Kher, S. , George, S. D. , Xu, M. , Wang-Gillam, A. , Samatar, A. A. , Maitra, A. , Wennerberg, K. , Petricoin, E. F. , Yin, H. H. & 4 others Nelkin, B., Cox, A. D., Yeh, J. J. & Der, C. J., Jan 11 2016, In : Cancer Cell. 29, 1, p. 75-89 15 p.

Research output: Contribution to journalArticle

Phosphatidylinositol 3-Kinase
Pancreatic Neoplasms
Cell Line
Mitogen-Activated Protein Kinase Kinases
Genetic Testing

A phase I trial of vertical inhibition of IGF signalling using cixutumumab, an anti-IGF-1R antibody, and selumetinib, an MEK 1/2 inhibitor, in advanced solid tumours

Wilky, B. A., Rudek, M. A., Ahmed, S., Laheru, D. A., Cosgrove, D., Donehower, R. C., Nelkin, B., Ball, D., Doyle, L. A., Chen, H., Ye, X., Bigley, G., Womack, C. & Azad, N. S., Jan 6 2015, In : British Journal of Cancer. 112, 1, p. 24-31 8 p.

Research output: Contribution to journalArticle

Mitogen-Activated Protein Kinase Kinases
Antibodies
Neoplasms
Maximum Tolerated Dose
Thyroid Neoplasms

Combined inhibition of cyclin-dependent kinases (dinaciclib) and AKT(MK-2206) blocks pancreatic tumor growth and metastases in patient-derived xenograft models

Hu, C., Dadon, T., Chenna, V., Yabuuchi, S., Bannerji, R., Booher, R., Strack, P., Azad, N., Nelkin, B. D. & Maitra, A., Jul 1 2015, In : Molecular Cancer Therapeutics. 14, 7, p. 1532-1539 8 p.

Research output: Contribution to journalArticle

Cyclin-Dependent Kinases
Pancreatic Neoplasms
Heterografts
Neoplasm Metastasis
Growth