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  • 3 Similar Profiles
Glutamate Carboxypeptidase II Medicine & Life Sciences
Glutamic Acid Medicine & Life Sciences
Therapeutics Medicine & Life Sciences
Brain Medicine & Life Sciences
Enzymes Medicine & Life Sciences
Drug Therapy Medicine & Life Sciences
Pharmacology Medicine & Life Sciences
Rats Chemical Compounds

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Research Output 1988 2017

Development of a primary microglia screening assay and its use to characterize inhibition of system xc - by erastin and its analogs

Figuera-Losada, M., Thomas, A. G., Stathis, M., Stockwell, B. R., Rojas, C. & Slusher, B. S. Mar 1 2017 In : Biochemistry and Biophysics Reports. 9, p. 266-272 7 p.

Research output: Research - peer-reviewArticle

Glutamic Acid
Assays
Screening
erastin
Microglia

Discovery of a para-Acetoxy-benzyl Ester Prodrug of a Hydroxamate-Based Glutamate Carboxypeptidase II Inhibitor as Oral Therapy for Neuropathic Pain

Rais, R., Vávra, J., Tichý, T., Dash, R. P., Gadiano, A. J., Tenora, L., Monincová, L., Bařinka, C., Alt, J., Zimmermann, S. C., Slusher, C. E., Wu, Y., Wozniak, K., Majer, P., Tsukamoto, T. & Slusher, B. S. Sep 28 2017 In : Journal of Medicinal Chemistry. 60, 18, p. 7799-7809 11 p.

Research output: Research - peer-reviewArticle

Glutamate Carboxypeptidase II
Prodrugs
Neuralgia
Esters
Therapeutics

Enhanced Brain Delivery of 2-(Phosphonomethyl)pentanedioic Acid Following Intranasal Administration of Its γ-Substituted Ester Prodrugs

Nedelcovych, M., Dash, R. P., Tenora, L., Zimmermann, S. C., Gadiano, A. J., Garrett, C., Alt, J., Hollinger, K. R., Pommier, E., Jančařík, A., Rojas, C., Thomas, A. G., Wu, Y., Wozniak, K., Majer, P., Slusher, B. S. & Rais, R. Oct 2 2017 In : Molecular Pharmaceutics. 14, 10, p. 3248-3257 10 p.

Research output: Research - peer-reviewArticle

Intranasal Administration
Prodrugs
Esters
Brain
2-(phosphonomethyl)pentanedioic acid

Glutamine antagonist-mediated immune suppression decreases pathology but delays virus clearance in mice during nonfatal alphavirus encephalomyelitis

Baxter, V. K., Glowinski, R., Braxton, A. M., Potter, M. C., Slusher, B. S. & Griffin, D. E. Aug 1 2017 In : Virology. 508, p. 134-149 16 p.

Research output: Research - peer-reviewArticle

Sindbis Virus
Alphavirus
Encephalomyelitis
Glutamine
Central Nervous System

Microtubule-Targeting Agents Eribulin and Paclitaxel Differentially Affect Neuronal Cell Bodies in Chemotherapy-Induced Peripheral Neuropathy

Benbow, S. J., Wozniak, K. M., Kulesh, B., Savage, A., Slusher, B. S., Littlefield, B. A., Jordan, M. A., Wilson, L. & Feinstein, S. C. Apr 8 2017 (Accepted/In press) In : Neurotoxicity Research. p. 1-12 12 p.

Research output: Research - peer-reviewArticle

eribulin
Peripheral Nervous System Diseases
Paclitaxel
Microtubules
Drug Therapy