Research output per year
Research output per year
Research output
- 73 Article
- 1 - 50 out of 73 results
Search results
-
2023
Preclinical Efficacy of LP-184, a Tumor Site Activated Synthetic Lethal Therapeutic, in Glioblastoma
Lal, B., Kulkarni, A., McDermott, J., Rais, R., Alt, J., Wu, Y., Lopez-Bertoni, H., Sall, S., Kathad, U., Zhou, J., Slusher, B. S., Bhatia, K. & Laterra, J., Oct 15 2023, In: Clinical Cancer Research. 29, 20, p. 4209-4218 10 p.Research output: Contribution to journal › Article › peer-review
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2022
ATRX loss promotes immunosuppressive mechanisms in IDH1 mutant glioma
Hu, C., Wang, K., Damon, C., Fu, Y., Ma, T., Kratz, L., Lal, B., Ying, M., Xia, S., Cahill, D. P., Jackson, C. M., Lim, M., Laterra, J. & Li, Y., Jun 1 2022, In: Neuro-oncology. 24, 6, p. 888-900 13 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Sox2 induces glioblastoma cell stemness and tumor propagation by repressing TET2 and deregulating 5hmC and 5mC DNA modifications
Lopez-Bertoni, H., Johnson, A., Rui, Y., Lal, B., Sall, S., Malloy, M., Coulter, J. B., Lugo-Fagundo, M., Shudir, S., Khela, H., Caputo, C., Green, J. J. & Laterra, J., Dec 2022, In: Signal Transduction and Targeted Therapy. 7, 1, 37.Research output: Contribution to journal › Article › peer-review
Open Access -
Targeting UDP-α-D-glucose 6-dehydrogenase alters the CNS tumor immune microenvironment and inhibits glioblastoma growth
Zhan, D., Yalcin, F., Ma, D., Fu, Y., Wei, S., Lal, B., Li, Y., Dzaye, O., Laterra, J., Ying, M., Lopez-Bertoni, H. & Xia, S., May 2022, In: Genes and Diseases. 9, 3, p. 717-730 14 p.Research output: Contribution to journal › Article › peer-review
Open Access -
The endosomal pH regulator NHE9 is a driver of stemness in glioblastoma
Ko, M., Makena, M. R., Schiapparelli, P., Suarez-Meade, P., Mekile, A. X., Lal, B., Lopez-Bertoni, H., Kozielski, K. L., Green, J. J., Laterra, J., Quinones-Hinojosa, A. & Rao, R., Mar 1 2022, In: PNAS Nexus. 1, 1, pgac013.Research output: Contribution to journal › Article › peer-review
Open Access -
2021
Egfr activates a taz-driven oncogenic program in glioblastoma
Gao, M., Fu, Y., Zhou, W., Gui, G., Lal, B., Li, Y., Xia, S., Ji, H., Eberhart, C. G., Laterra, J. & Ying, M., Jul 1 2021, In: Cancer Research. 81, 13, p. 3580-3592 13 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Monoallelic IDH1 R132H mutation mediates glioma cell response to anticancer therapies via induction of senescence
Zhan, D., Ma, D., Wei, S., Lal, B., Fu, Y., Eberhart, C., Laterra, J., Ying, M., Li, Y., Meeker, A., Lopez-Bertoni, H. & Xia, S., Nov 2021, In: Molecular Cancer Research. 19, 11, p. 1878-1888 11 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Mutant IDH1 promotes phagocytic function of microglia/macrophages in gliomas by downregulating ICAM1
Ma, D., Zhan, D., Fu, Y., Wei, S., Lal, B., Wang, J., Li, Y., Lopez-Bertoni, H., Yalcin, F., Dzaye, O., Eberhart, C. G., Laterra, J., Wilson, M. A., Ying, M. & Xia, S., Oct 1 2021, In: Cancer Letters. 517, p. 35-45 11 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Reprogramming transcription factors Oct4 and Sox2 induce a BRD-dependent immunosuppressive transcriptome in GBM-propagating cells
Ma, T., Hu, C., Lal, B., Zhou, W., Ma, Y., Ying, M., Prinos, P., Quiñones-Hinojosa, A., Lim, M., Laterra, J. & Li, Y., May 1 2021, In: Cancer Research. 81, 9, p. 2457-2469 13 p.Research output: Contribution to journal › Article › peer-review
Open Access -
2020
A Sox2:miR-486-5p axis regulates survival of GBM cells by inhibiting tumor suppressor networks
Lopez-Bertoni, H., Kotchetkov, I. S., Mihelson, N., Lal, B., Rui, Y., Ames, H., Lugo-Fagundo, M., Guerrero-Cazares, H., Quinones-Hinojosa, A., Green, J. J. & Laterra, J., Apr 15 2020, In: Cancer Research. 80, 8, p. 1644-1655 12 p.Research output: Contribution to journal › Article › peer-review
Open Access10 Scopus citations -
ShRNA-based POLD2 expression knockdown sensitizes glioblastoma to DNA-Damaging therapeutics
Xu, Q., Hu, C., Zhu, Y., Wang, K., Lal, B., Li, L., Tang, J., Wei, S., Huang, G., Xia, S., Lv, S., Laterra, J., Jiang, Y. & Li, Y., Jul 10 2020, In: Cancer Letters. 482, p. 126-135 10 p.Research output: Contribution to journal › Article › peer-review
3 Scopus citations -
2019
CEST MRI of 3-O-methyl-D-glucose uptake and accumulation in brain tumors
Sehgal, A. A., Li, Y., Lal, B., Yadav, N. N., Xu, X., Xu, J., Laterra, J. & van Zijl, P. C. M., Mar 2019, In: Magnetic resonance in medicine. 81, 3, p. 1993-2000 8 p.Research output: Contribution to journal › Article › peer-review
13 Scopus citations -
Extracellular matrix protein tenascin C increases phagocytosis mediated by CD47 Loss of function in glioblastoma
Ma, D., Liu, S., Lal, B., Wei, S., Wang, S., Zhan, D., Zhang, H., Lee, R. S., Gao, P., Lopez-Bertoni, H., Ying, M., Li, J. J., Laterra, J., Wilson, M. A. & Xia, S., 2019, In: Cancer Research. 79, 10, p. 2697-2708 12 p.Research output: Contribution to journal › Article › peer-review
Open Access12 Scopus citations -
The effect of the mTOR inhibitor rapamycin on glucoCEST signal in a preclinical model of glioblastoma
Xu, X., Xu, J., Knutsson, L., Liu, J., Liu, H., Li, Y., Lal, B., Laterra, J., Artemov, D., Liu, G., van Zijl, P. C. M. & Chan, K. W. Y., Jun 2019, In: Magnetic resonance in medicine. 81, 6, p. 3798-3807 10 p.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
2018
Bioreducible Polymeric Nanoparticles Containing Multiplexed Cancer Stem Cell Regulating miRNAs Inhibit Glioblastoma Growth and Prolong Survival
Lopez-Bertoni, H., Kozielski, K. L., Rui, Y., Lal, B., Vaughan, H., Wilson, D. R., Mihelson, N., Eberhart, C. G., Laterra, J. & Green, J. J., Jul 11 2018, In: Nano Letters. 18, 7, p. 4086-4094 9 p.Research output: Contribution to journal › Article › peer-review
Open Access55 Scopus citations -
Crizotinib and erlotinib inhibits growth of c-Met+/EGFRvIII+ primary human glioblastoma xenografts
Goodwin, C. R., Rath, P., Oyinlade, O., Lopez, H., Mughal, S., Xia, S., Li, Y., Kaur, H., Zhou, X., Ahmed, A. K., Ho, S., Olivi, A. & Lal, B., Aug 2018, In: Clinical Neurology and Neurosurgery. 171, p. 26-33 8 p.Research output: Contribution to journal › Article › peer-review
13 Scopus citations -
Heterozygous IDH1 R132H/WT created by “single base editing” inhibits human astroglial cell growth by downregulating YAP
Wei, S., Wang, J., Oyinlade, O., Ma, D., Wang, S., Kratz, L., Lal, B., Xu, Q., Liu, S., Shah, S. R., Zhang, H., Li, Y., Quiñones-Hinojosa, A., Zhu, H., Huang, Z. Y., Cheng, L., Qian, J. & Xia, S., Sep 20 2018, In: Oncogene. 37, 38, p. 5160-5174 15 p.Research output: Contribution to journal › Article › peer-review
Open Access13 Scopus citations -
Targeting UDP-α-d-glucose 6-dehydrogenase inhibits glioblastoma growth and migration
Oyinlade, O., Wei, S., Lal, B., Laterra, J., Zhu, H., Goodwin, C. R., Wang, S., Ma, D., Wan, J. & Xia, S., May 1 2018, In: Oncogene. 37, 20, p. 2615-2629 15 p.Research output: Contribution to journal › Article › peer-review
Open Access16 Scopus citations -
2016
A monoclonal antibody against KCNK9 K+ channel extracellular domain inhibits tumour growth and metastasis
Sun, H., Luo, L., Lal, B., Ma, X., Chen, L., Hann, C. L., Fulton, A. M., Leahy, D. J., Laterra, J. & Li, M., Feb 4 2016, In: Nature communications. 7, 10339.Research output: Contribution to journal › Article › peer-review
Open Access30 Scopus citations -
Epigenetic modulation of a miR-296-5p:HMGA1 axis regulates Sox2 expression and glioblastoma stem cells
Lopez-Bertoni, H., Lal, B., Michelson, N., Guerrero-Cázares, H., Quinõnes-Hinojosa, A., Li, Y. & Laterra, J., Sep 15 2016, In: Oncogene. 35, 37, p. 4903-4913 11 p.Research output: Contribution to journal › Article › peer-review
Open Access38 Scopus citations -
Regulation of Glioblastoma Tumor-Propagating Cells by the Integrin Partner Tetraspanin CD151
Tilghman, J., Schiapparelli, P., Lal, B., Ying, M., Quinones-Hinojosa, A., Xia, S. & Laterra, J., 2016, In: Neoplasia (United States). 18, 3, p. 185-198 14 p.Research output: Contribution to journal › Article › peer-review
Open Access12 Scopus citations -
Salicylic Acid Conjugated Dendrimers Are a Tunable, High Performance CEST MRI NanoPlatform
Lesniak, W. G., Oskolkov, N., Song, X., Lal, B., Yang, X., Pomper, M., Laterra, J., Nimmagadda, S. & McMahon, M. T., Apr 13 2016, In: Nano Letters. 16, 4, p. 2248-2253 6 p.Research output: Contribution to journal › Article › peer-review
Open Access28 Scopus citations -
Tumor microenvironment tenascin-C promotes glioblastoma invasion and negatively regulates tumor proliferation
Xia, S., Lal, B., Tung, B., Wang, S., Goodwin, C. R. & Laterra, J., Apr 1 2016, In: Neuro-oncology. 18, 4, p. 507-517 11 p.Research output: Contribution to journal › Article › peer-review
Open Access64 Scopus citations -
2015
DNMT-dependent suppression of microRNA regulates the induction of GBM tumor-propagating phenotype by Oct4 and Sox2
Lopez-Bertoni, H., Lal, B., Li, A., Caplan, M., Guerrero-Cázares, H., Eberhart, C. G., Quiñones-Hinojosa, A., Glas, M., Scheffler, B., Laterra, J. & Li, Y., Jul 23 2015, In: Oncogene. 34, 30, p. 3994-4004 11 p.Research output: Contribution to journal › Article › peer-review
Open Access52 Scopus citations -
Dynamic glucose enhanced (DGE) MRI for combined imaging of blood-brain barrier break down and increased blood volume in brain cancer
Xu, X., Chan, K. W. Y., Knutsson, L., Artemov, D., Xu, J., Liu, G., Kato, Y., Lal, B., Laterra, J., McMahon, M. T. & Van Zijl, P. C. M., Dec 1 2015, In: Magnetic resonance in medicine. 74, 6, p. 1556-1563 8 p.Research output: Contribution to journal › Article › peer-review
Open Access56 Scopus citations -
Multi-echo length and offset VARied saturation (MeLOVARS) method for improved CEST imaging
Song, X., Xu, J., Xia, S., Yadav, N. N., Lal, B., Laterra, J., Bulte, J. W. M., Van Zijl, P. C. M. & McMahon, M. T., Feb 1 2015, In: Magnetic resonance in medicine. 73, 2, p. 488-496 9 p.Research output: Contribution to journal › Article › peer-review
Open Access20 Scopus citations -
2014
Combination of anti-VEGF therapy and temozolomide in two experimental human glioma models
Grossman, R., Brastianos, H., Blakeley, J. O., Mangraviti, A., Lal, B., Zadnik, P., Hwang, L., Wicks, R. T., Goodwin, R. C., Brem, H. & Tyler, B., Jan 2014, In: Journal of neuro-oncology. 116, 1, p. 59-65 7 p.Research output: Contribution to journal › Article › peer-review
Open Access13 Scopus citations -
Lipid metabolism enzyme ACSVL3 supports glioblastoma stem cell maintenance and tumorigenicity
Sun, P., Xia, S., Lal, B., Shi, X., Yang, K. S., Watkins, P. A. & Laterra, J., Jun 4 2014, In: BMC cancer. 14, 1, 401.Research output: Contribution to journal › Article › peer-review
Open Access19 Scopus citations -
Quantitative multiparametric MRI assessment of glioma response to radiotherapy in a rat model
Hong, X., Liu, L., Wang, M., Ding, K., Fan, Y., Ma, B., Lal, B., Tyler, B., Mangraviti, A., Wang, S., Wong, J., Laterra, J. & Zhou, J., Jun 2014, In: Neuro-oncology. 16, 6, p. 856-867 12 p.Research output: Contribution to journal › Article › peer-review
Open Access31 Scopus citations -
2013
In vivo c-Met pathway inhibition depletes human glioma xenografts of tumor-propagating stem-like cells
Rath, P., Lal, B., Ajala, O., Li, Y., Xia, S., Kim, J. & Laterra, J., Apr 2013, In: Translational Oncology. 6, 2, p. 104-111 8 p.Research output: Contribution to journal › Article › peer-review
Open Access39 Scopus citations -
2012
Collagen IV and CXC chemokine-derived antiangiogenic peptides suppress glioma xenograft growth
Rosca, E. V., Lal, B., Koskimaki, J. E., Popel, A. S. & Laterra, J., Aug 2012, In: Anti-cancer drugs. 23, 7, p. 706-712 7 p.Research output: Contribution to journal › Article › peer-review
Open Access14 Scopus citations -
EphB2 receptor controls proliferation/migration dichotomy of glioblastoma by interacting with focal adhesion kinase
Wang, S. D., Rath, P., Lal, B., Richard, J-P., Li, Y., Goodwin, C. R., Laterra, J. & Xia, S., Dec 13 2012, In: Oncogene. 31, 50, p. 5132-5143 12 p.Research output: Contribution to journal › Article › peer-review
56 Scopus citations -
Evaluation of radiation necrosis and malignant glioma in rat models using diffusion tensor MR imaging
Wang, S., Chen, Y., Lal, B., Ford, E., Tryggestad, E., Armour, M., Yan, K., Laterra, J. & Zhou, J., Mar 2012, In: Journal of neuro-oncology. 107, 1, p. 51-60 10 p.Research output: Contribution to journal › Article › peer-review
Open Access20 Scopus citations -
2011
c-Met signaling induces a reprogramming network and supports the glioblastoma stem-like phenotype
Li, Y., Li, A., Glas, M., Lal, B., Ying, M., Sang, Y., Xia, S., Trageser, D., Guerrero-Cázares, H., Eberhart, C. G., Quiñones-Hinojosa, A., Scheffler, B. & Laterra, J., Jun 14 2011, In: Proceedings of the National Academy of Sciences of the United States of America. 108, 24, p. 9951-9956 6 p.Research output: Contribution to journal › Article › peer-review
Open Access184 Scopus citations -
Differentiation between glioma and radiation necrosis using molecular magnetic resonance imaging of endogenous proteins and peptides
Zhou, J., Tryggestad, E., Wen, Z., Lal, B., Zhou, T., Grossman, R., Wang, S., Yan, K., Fu, D. X., Ford, E., Tyler, B., Blakeley, J., Laterra, J. & Van Zijl, P. C. M., Jan 2011, In: Nature medicine. 17, 1, p. 130-134 5 p.Research output: Contribution to journal › Article › peer-review
Open Access317 Scopus citations -
Improvement in the standard treatment for experimental glioma by fusing antibody Fc domain to endostatin: Laboratory investigation
Grossman, R., Tyler, B., Hwang, L., Zadnik, P., Lal, B., Javaherian, K. & Brem, H., Dec 2011, In: Journal of neurosurgery. 115, 6, p. 1139-1146 8 p.Research output: Contribution to journal › Article › peer-review
9 Scopus citations -
PTEN reconstitution alters glioma responses to c-Met pathway inhibition
Rory Goodwin, C., Lal, B., Ho, S., Woodard, C. L., Zhou, X., Taeger, A., Xia, S. & Laterra, J., Oct 2011, In: Anti-cancer drugs. 22, 9, p. 905-912 8 p.Research output: Contribution to journal › Article › peer-review
Open Access12 Scopus citations -
Regulation of glioblastoma stem cells by retinoic acid: Role for Notch pathway inhibition
Ying, M., Wang, S., Sang, Y., Sun, P., Lal, B., Goodwin, C. R., Guerrero-Cazares, H., Quinones-Hinojosa, A., Laterra, J. & Xia, S., Aug 4 2011, In: Oncogene. 30, 31, p. 3454-3467 14 p.Research output: Contribution to journal › Article › peer-review
Open Access118 Scopus citations -
2010
Cyr61 mediates hepatocyte growth factor-dependent tumor cell growth, migration, and Akt activation
Goodwin, C. R., Lal, B., Zhou, X., Ho, S., Xia, S., Taeger, A., Murray, J. & Laterra, J., Apr 1 2010, In: Cancer Research. 70, 7, p. 2932-2941 10 p.Research output: Contribution to journal › Article › peer-review
Open Access43 Scopus citations -
2009
Acyl-CoA synthetase VL3 knockdown inhibits human glioma cell proliferation and tumorigenicity
Pei, Z., Sun, P., Huang, P., Lal, B., Laterra, J. & Watkins, P. A., Dec 15 2009, In: Cancer Research. 69, 24, p. 9175-9182 8 p.Research output: Contribution to journal › Article › peer-review
Open Access24 Scopus citations -
DNER, an epigenetically modulated gene, regulates glioblastoma-derived neurosphere cell differentiation and tumor propagation
Sun, P., Xia, S., Lal, B., Eberhart, C. G., Quinones-Hinojosa, A., Maciaczyk, J., Matsui, W., DiMeco, F., Piccirillo, S. M., Vescovi, A. L. & Laterra, J., Jul 2009, In: Stem Cells. 27, 7, p. 1473-1486 14 p.Research output: Contribution to journal › Article › peer-review
Open Access67 Scopus citations -
EGFRvIII and c-Met pathway inhibitors synergize against PTEN-null/EGFRvIII+ glioblastoma xenografts
Lal, B., Goodwin, C. R., Sang, Y., Foss, C. A., Cornet, K., Muzamil, S., Pomper, M. G., Kim, J. & Laterra, J., Jul 1 2009, In: Molecular cancer therapeutics. 8, 7, p. 1751-1760 10 p.Research output: Contribution to journal › Article › peer-review
Open Access53 Scopus citations -
2008
Amide proton transfer imaging of 9L gliosarcoma and human glioblastoma xenografts
Salhotra, A., Lal, B., Laterra, J., Zhe Sun, P., van Zijl, P. C. M. & Zhou, J., Jun 2008, In: NMR in biomedicine. 21, 5, p. 489-497 9 p.Research output: Contribution to journal › Article › peer-review
Open Access73 Scopus citations -
Functional and molecular interactions between the HGF/c-Met pathway and c-Myc in large-cell medulloblastoma
Li, Y., Guessous, F., Johnson, E. B., Eberhart, C. G., Li, X. N., Shu, Q., Fan, S., Lal, B., Laterra, J., Schiff, D. & Abounader, R., Feb 2008, In: Laboratory Investigation. 88, 2, p. 98-111 14 p.Research output: Contribution to journal › Article › peer-review
Open Access56 Scopus citations -
Hepatocyte growth factor and Sonic Hedgehog expression in cerebellar neural progenitor cells costimulate medulloblastoma initiation and growth
Binning, M. J., Niazi, T., Pedone, C. A., Lal, B., Eberhart, C. G., Kim, K. J., Laterra, O. & Fults, D. W., Oct 1 2008, In: Cancer Research. 68, 19, p. 7838-7845 8 p.Research output: Contribution to journal › Article › peer-review
Open Access34 Scopus citations -
PTEN has tumor-promoting properties in the setting of gain-of-function p53 mutations
Li, Y., Guessous, F., Kwon, S., Kumar, M., Ibidapo, O., Fuller, L., Johnson, E., Lal, B., Hussaini, I., Bao, Y., Laterra, J., Schiff, D. & Abounader, R., Mar 15 2008, In: Cancer Research. 68, 6, p. 1723-1731 9 p.Research output: Contribution to journal › Article › peer-review
Open Access72 Scopus citations -
2007
ABCG2/BCRP expression modulates D-luciferin-based bioluminescence imaging
Zhang, Y., Bressler, J. P., Neal, J., Lal, B., Bhang, H. E. C., Laterra, J. & Pomper, M. G., Oct 1 2007, In: Cancer Research. 67, 19, p. 9389-9397 9 p.Research output: Contribution to journal › Article › peer-review
Open Access67 Scopus citations -
Unique patterns of diffusion directionality in rat brain tumors revealed by high-resolution diffusion tensor MRI
Zhang, J., Van Zijl, P. C. M., Laterra, J., Salhotra, A., Lal, B., Mori, S. & Zhou, J., Sep 2007, In: Magnetic resonance in medicine. 58, 3, p. 454-462 9 p.Research output: Contribution to journal › Article › peer-review
Open Access43 Scopus citations -
2006
Systemic anti-hepatocyte growth factor monoclonal antibody therapy induces the regression of intracranial glioma xenografts
Kim, K. J., Wang, L., Su, Y. C., Gillespie, G. Y., Salhotra, A., Lal, B. & Laterra, J., Feb 15 2006, In: Clinical Cancer Research. 12, 4, p. 1292-1298 7 p.Research output: Contribution to journal › Article › peer-review
Open Access138 Scopus citations -
2005
Targeting the c-Met pathway potentiates glioblastoma responses to γ-radiation
Lal, B., Xia, S., Abounader, R. & Laterra, J., Jun 15 2005, In: Clinical Cancer Research. 11, 12, p. 4479-4486 8 p.Research output: Contribution to journal › Article › peer-review
101 Scopus citations