Apua Paquola

Assistant Professor

20032019
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Fingerprint Dive into the research topics where Apua Paquola is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 5 Similar Profiles
Neurons Medicine & Life Sciences
Induced Pluripotent Stem Cells Medicine & Life Sciences
Mosaicism Medicine & Life Sciences
Genes Medicine & Life Sciences
Genome Medicine & Life Sciences
Transcriptome Medicine & Life Sciences
Serotonergic Neurons Medicine & Life Sciences
Brain Medicine & Life Sciences

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Research Output 2003 2019

Altered serotonergic circuitry in SSRI-resistant major depressive disorder patient-derived neurons

Vadodaria, K. C., Ji, Y., Skime, M., Paquola, A., Nelson, T., Hall-Flavin, D., Heard, K. J., Fredlender, C., Deng, Y., Elkins, J., Dani, K., Le, A. T., Marchetto, M. C., Weinshilboum, R. & Gage, F. H., Jan 1 2019, In : Molecular psychiatry.

Research output: Contribution to journalArticle

Major Depressive Disorder
Serotonin Uptake Inhibitors
Serotonergic Neurons
Neurons
Induced Pluripotent Stem Cells

Chemical modulation of transcriptionally enriched signaling pathways to optimize the conversion of fibroblasts into neurons

Herdy, J., Schafer, S., Kim, Y., Ansari, Z., Zangwill, D., Ku, M., Paquola, A., Lee, H., Mertens, J. & Gage, F. H., May 17 2019, In : eLife. 8

Research output: Contribution to journalArticle

Open Access
Fibroblasts
Neurons
Modulation
Technology
Gene Transfer Techniques

Pathological priming causes developmental gene network heterochronicity in autistic subject-derived neurons

Schafer, S. T., Paquola, A., Stern, S., Gosselin, D., Ku, M., Pena, M., Kuret, T. J. M., Liyanage, M., Mansour, A. A. F., Jaeger, B. N., Marchetto, M. C., Glass, C. K., Mertens, J. & Gage, F. H., Jan 1 2019, (Accepted/In press) In : Nature Neuroscience.

Research output: Contribution to journalArticle

Developmental Genes
Gene Regulatory Networks
Neurons
Neural Stem Cells
Induced Pluripotent Stem Cells

Serotonin-induced hyperactivity in SSRI-resistant major depressive disorder patient-derived neurons

Vadodaria, K. C., Ji, Y., Skime, M., Paquola, A., Nelson, T., Hall-Flavin, D., Fredlender, C., Heard, K. J., Deng, Y., Le, A. T., Dave, S., Fung, L., Li, X., Marchetto, M. C., Weinshilboum, R. & Gage, F. H., Jan 1 2019, In : Molecular Psychiatry.

Research output: Contribution to journalArticle

Major Depressive Disorder
Serotonin Uptake Inhibitors
Serotonin
Neurons
Synaptic Transmission

Studying treatment resistance in depression using patient derived neurons in vitro

Vadodaria, K. C., Ji, Y., Skime, M., Paquola, A., Nelson, T., Hall-Flavin, D., Fredlender, C., Heard, K. J., Deng, Y., Le, A. T., Dave, S., Fung, L., Li, X., Marchetto, M. C., Weinshilboum, R. & Gage, F. H., Jun 1 2019, In : Molecular psychiatry. 24, 6, 1 p.

Research output: Contribution to journalComment/debate

Neurons
Therapeutics
In Vitro Techniques