Research output per year
Research output per year
- 1 - 50 out of 186 results
Search results
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2024
Anti-Gephyrin Antibodies: A Novel Specificity in Patients With Systemic Sclerosis and Lower Bowel Dysfunction
McMahan, Z. H., Kulkarni, S., Andrade, F., Perin, J., Zhang, C., Hooper, J. E., Wigley, F. M., Rosen, A., Pasricha, P. J. & Casciola-Rosen, L., Jan 2024, In: Arthritis and Rheumatology. 76, 1, p. 92-99 8 p.Research output: Contribution to journal › Article › peer-review
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Distinct Scleroderma Autoantibody Profiles Stratify Patients for Cancer Risk at Scleroderma Onset and During the Disease Course
Kim, J. S., Woods, A., Gutierrez-Alamillo, L., Laffoon, M., Wigley, F. M., Hummers, L. K., Rosen, A., Zeger, S., Domsic, R. T., Casciola-Rosen, L. & Shah, A. A., Jan 2024, In: Arthritis and Rheumatology. 76, 1, p. 68-77 10 p.Research output: Contribution to journal › Article › peer-review
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2023
Association of Anti-CCAR1 Autoantibodies With Decreased Cancer Risk Relative to the General Population in Patients With Anti–Transcriptional Intermediary Factor 1γ–Positive Dermatomyositis
Fiorentino, D., Mecoli, C. A., Igusa, T., Albayda, J., Paik, J. J., Tiniakou, E., Adler, B., Mammen, A. L., Shah, A. A., Rosen, A., Christopher-Stine, L. & Casciola-Rosen, L., Jul 2023, In: Arthritis and Rheumatology. 75, 7, p. 1238-1245 8 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Cumulative disease damage and anti-PM/Scl antibodies are associated with a heavy burden of calcinosis in systemic sclerosis
Richardson, C., Perin, J., Zeger, S., Wigley, F. M., Hummers, L. K., Casciola-Rosen, L., Rosen, A. & Shah, A. A., Nov 1 2023, In: Rheumatology (United Kingdom). 62, 11, p. 3636-3643 8 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Subsets of Idiopathic Inflammatory Myositis Enriched for Contemporaneous Cancer Relative to the General Population
Mecoli, C. A., Igusa, T., Chen, M., Wang, X. Y., Albayda, J., Paik, J. J., Tiniakou, E., Adler, B., Richardson, C., Kelly, W., Danoff, S., Mammen, A. L., Platz, E. A., Rosen, A., Christopher-Stine, L., Casciola-Rosen, L. & Shah, A. A., Apr 2023, In: Arthritis and Rheumatology. 75, 4, p. 620-629 10 p.Research output: Contribution to journal › Article › peer-review
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The XIST lncRNA is a sex-specific reservoir of TLR7 ligands in SLE
Crawford, J. D., Wang, H., Trejo-Zambrano, D., Cimbro, R., Talbot, C. C., Thomas, M. A., Curran, A. M., Girgis, A. A., Schroeder, J. T., Fava, A., Goldman, D. W., Petri, M., Rosen, A., Antiochos, B. & Darrah, E. D., Oct 2023, In: JCI Insight. 8, 20, e169344.Research output: Contribution to journal › Article › peer-review
Open Access -
2022
Autoantibodies targeting LINE-1-encoded ORF1p are associated with systemic lupus erythematosus diagnosis but not with disease activity
Antiochos, B., Paz, M., Li, J., Goldman, D. W., Petri, M., Darrah, E., Cashman, K., Sanz, I., Burns, K. H., Ardeljan, D., Andrade, F. & Rosen, A., Sep 2022, In: Clinical and experimental rheumatology. 40, 9, p. 1636-1641 6 p.Research output: Contribution to journal › Article › peer-review
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IgM anti-ACE2 autoantibodies in severe COVID-19 activate complement and perturb vascular endothelial function
Casciola-Rosen, L., Thiemann, D. R., Andrade, F., Trejo-Zambrano, M. I., Leonard, E. K., Spangler, J. B., Skinner, N. E., Bailey, J., Yegnasubramanian, S., Wang, R., Vaghasia, A. M., Gupta, A., Cox, A. L., Ray, S. C., Linville, R. M., Guo, Z., Searson, P. C., Machamer, C. E., Desiderio, S., Sauer, L., & 18 others, May 9 2022, In: JCI Insight. 7, 9, e158362.Research output: Contribution to journal › Article › peer-review
Open Access -
Immune responses to CCAR1 and other dermatomyositis autoantigens are associated with attenuated cancer emergence
Fiorentino, D. F., Mecoli, C. A., Rosen, M. C., Chung, L. S., Christopher-Stine, L., Rosen, A. & Casciola-Rosen, L., Jan 18 2022, In: Journal of Clinical Investigation. 132, 2, 150201.Research output: Contribution to journal › Article › peer-review
Open Access -
Learning and Predicting from Dynamic Models for COVID-19 Patient Monitoring
Wang, Z., Bowring, M. G., Rosen, A., Garibaldi, B., Zeger, S. & Nishimura, A., May 2022, In: Statistical Science. 37, 2, p. 251-265 15 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Mechanisms of Autoimmunity
Johnson, T., Antiochos, B. & Rosen, A., Jan 1 2022, Clinical Immunology: Principles and Practice, Sixth Edition. Elsevier, p. 649-656 8 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter
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Presence and Implications of Anti-Angiotensin Converting Enzyme-2 Immunoglobulin M Antibodies in Anti-Melanoma-Differentiation-Associated 5 Dermatomyositis
Mecoli, C. A., Yoshida, A., Paik, J. J., Lin, C. T., Danoff, S., Hanaoka, H., Rosen, A., Christopher-Stine, L., Kuwana, M. & Casciola-Rosen, L., May 2022, In: ACR Open Rheumatology. 4, 5, p. 457-463 7 p.Research output: Contribution to journal › Article › peer-review
Open Access -
The DNA sensors AIM2 and IFI16 are SLE autoantigens that bind neutrophil extracellular traps
Antiochos, B., Trejo-Zambrano, D., Fenaroli, P., Rosenberg, A., Baer, A., Garg, A., Sohn, J., Li, J., Petri, M., Goldman, D. W., Mecoli, C., Casciola-Rosen, L. & Rosen, A., May 2022, In: eLife. 11, e72103.Research output: Contribution to journal › Article › peer-review
Open Access -
2021
A Bayesian approach to restricted latent class models for scientifically structured clustering of multivariate binary outcomes
Wu, Z., Casciola-Rosen, L., Rosen, A. & Zeger, S. L., Dec 2021, In: Biometrics. 77, 4, p. 1431-1444 14 p.Research output: Contribution to journal › Article › peer-review
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Association of systemic lupus erythematosus autoantibody diversity with breast cancer protection
Shah, A. A., Igusa, T., Goldman, D., Li, J., Casciola-Rosen, L., Rosen, A. & Petri, M., Dec 2021, In: Arthritis Research and Therapy. 23, 1, 64.Research output: Contribution to journal › Article › peer-review
Open Access -
Autoantibodies targeting telomere-associated proteins in systemic sclerosis
Adler, B. L., Boin, F., Wolters, P. J., Bingham, C. O., Shah, A. A., Greider, C., Casciola-Rosen, L. & Rosen, A., Jul 1 2021, In: Annals of the rheumatic diseases. 80, 7, p. 912-919 8 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Cancer in Systemic Sclerosis: Analysis of Antibodies Against Components of the Th/To Complex
Mecoli, C. A., Adler, B. L., Yang, Q., Hummers, L. K., Rosen, A., Casciola-Rosen, L. & Shah, A. A., Feb 2021, In: Arthritis and Rheumatology. 73, 2, p. 315-323 9 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Granzyme B induces IRF-3 phosphorylation through a perforin-independent proteolysis-dependent signaling cascade without inducing cell death
Gapud, E. J., Trejo-Zambrano, M. I., Gomez-Banuelos, E., Tiniakou, E., Antiochos, B., Granville, D. J., Andrade, F., Casciola-Rosen, L. & Rosen, A., Jan 15 2021, In: Journal of Immunology. 206, 2, p. 335-344 10 p.Research output: Contribution to journal › Article › peer-review
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Patient trajectories among persons hospitalized for covid-19
Garibaldi, B. T., Fiksel, J., Muschelli, J., Robinson, M. L., Rouhizadeh, M., Perin, J., Schumock, G., Nagy, P., Gray, J. H., Malapati, H., Ghobadi-Krueger, M., Niessen, T. M., Kim, B. S., Hill, P. M., Ahmed, M. S., Dobkin, E. D., Blanding, R., Abele, J., Woods, B., Harkness, K., & 8 others, Jan 1 2021, In: Annals of internal medicine. 174, 1, p. 33-41 9 p.Research output: Contribution to journal › Review article › peer-review
Open Access20 Scopus citations -
2020
Advances at the interface of cancer and systemic sclerosis
Mecoli, C. A., Rosen, A., Casciola-Rosen, L. & Shah, A. A., 2020, (Accepted/In press) In: Journal of Scleroderma and Related Disorders.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
2019
Anti-retinoblastoma Protein Antibodies: A New Specificity in Systemic Lupus Erythematosus Associated With Protection Against Lupus Nephritis
Goules, A., Li, J., Antiochos, B., Goldman, D. W., Rosen, A., Petri, M. & Casciola-Rosen, L., Jul 1 2019, In: ACR Open Rheumatology. 1, 5, p. 287-291 5 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Association of Baseline Peptidylarginine Deiminase 4 Autoantibodies With Favorable Response to Treatment Escalation in Rheumatoid Arthritis
Darrah, E., Yu, F., Cappelli, L. C., Rosen, A., O'Dell, J. R. & Mikuls, T. R., May 2019, In: Arthritis and Rheumatology. 71, 5, p. 696-702 7 p.Research output: Contribution to journal › Article › peer-review
8 Scopus citations -
Estimating autoantibody signatures to detect autoimmune disease patient subsets
Wu, Z., Casciola-Rosen, L., Shah, A. A., Rosen, A. & Zeger, S. L., Jan 1 2019, In: Biostatistics. 20, 1, p. 30-47 18 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Mechanisms of Autoimmunity
Antiochos, B. & Rosen, A., Jan 1 2019, Clinical Immunology: Principles and Practice. Elsevier, p. 677-684.e1Research output: Chapter in Book/Report/Conference proceeding › Chapter
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Precision medicine: Discovering clinically relevant and mechanistically anchored disease subgroups at scale
Rosen, A. & Zeger, S. L., Mar 2019, In: Journal of Clinical Investigation. 129, 3, p. 944-945 2 p.Research output: Contribution to journal › Comment/debate › peer-review
Open Access7 Scopus citations -
Protective Effect Against Cancer of Antibodies to the Large Subunits of Both RNA Polymerases I and III in Scleroderma
Shah, A. A., Laiho, M., Rosen, A. & Casciola-Rosen, L., Sep 1 2019, In: Arthritis and Rheumatology. 71, 9, p. 1571-1579 9 p.Research output: Contribution to journal › Article › peer-review
Open Access11 Scopus citations -
The autoimmune myopathies
Casciola-Rosen, L. & Rosen, A., Jan 1 2019, The Autoimmune Diseases. Elsevier, p. 703-713 11 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter
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2018
Affinity maturation shapes the function of agonistic antibodies to peptidylarginine deiminase type 4 in rheumatoid arthritis
Shi, J., Darrah, E., Sims, G. P., Mustelin, T., Sampson, K., Konig, M. F., Bingham, C. O., Rosen, A. & Andrade, F., Jan 2018, In: Annals of the rheumatic diseases. 77, 1, p. 141-148 8 p.Research output: Contribution to journal › Article › peer-review
Open Access11 Scopus citations -
Autoantibodies and scleroderma phenotype define subgroups at high-risk and low-risk for cancer
Igusa, T., Hummers, L. K., Visvanathan, K., Richardson, C., Wigley, F. M., Casciola-Rosen, L., Rosen, A. & Shah, A. A., Aug 1 2018, In: Annals of the rheumatic diseases. 77, 8, p. 1180-1187 8 p.Research output: Contribution to journal › Article › peer-review
36 Scopus citations -
IFI16 filament formation in salivary epithelial cells shapes the anti-IFI16 immune response in Sjögren's syndrome
Antiochos, B., Matyszewski, M., Sohn, J., Casciola-Rosen, L. & Rosen, A., Sep 20 2018, In: JCI Insight. 3, 18Research output: Contribution to journal › Article › peer-review
Open Access10 Scopus citations -
Moments of Wonder
Rosen, A., Jul 2018, In: American Journal of Medicine. 131, 7, p. 852-853 2 p.Research output: Contribution to journal › Comment/debate › peer-review
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Rare loss of function variants in candidate genes and risk of colorectal cancer
NHLBI GO Exome Sequencing Project, Pulmonary Arterial Hypertension (PAH), Severe Asthma Research Program (SARP), Women’s Health Initiative (WHI), Anthropometry Project Team, Blood Count/Hematology Project Team, Blood Pressure Project Team, Data Flow Working Group, Early MI Project Team, ELSI Working Group, Executive Committee, Family Study Project Team, Lipids Project Team, Lung Project Team, Personal Genomics Project Team, Phenotype and Harmonization Working Group, Population Genetics and Statistical Analysis Working Group, Publications and Presentations Working Group, Quantitative Analysis Ad Hoc Task Group, Sequencing and Genotyping Working Group, & 15 others, Oct 1 2018, In: Human genetics. 137, 10, p. 795-806 12 p.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
2017
Brief Report: Anti–RNPC-3 Antibodies As a Marker of Cancer-Associated Scleroderma
Shah, A. A., Xu, G., Rosen, A., Hummers, L. K., Wigley, F. M., Elledge, S. J. & Casciola-Rosen, L., Jun 2017, In: Arthritis and Rheumatology. 69, 6, p. 1306-1312 7 p.Research output: Contribution to journal › Article › peer-review
Open Access28 Scopus citations -
Creating a purpose-driven learning and improving health system: The Johns Hopkins Medicine quality and safety experience
Pronovost, P. J., Mathews, S. C., Chute, C. G. & Rosen, A., Jan 2017, In: Learning Health Systems. 1, 1, e10018.Research output: Contribution to journal › Article › peer-review
Open Access14 Scopus citations -
Evaluation of cancer-associated myositis and scleroderma autoantibodies in breast cancer patients without rheumatic disease
Shah, A. A., Rosen, A., Hummers, L. K., May, B. J., Kaushiva, A., Roden, R. B. S., Armstrong, D. K., Wigley, F. M., Casciola-Rosen, L. & Visvanathan, K., 2017, In: Clinical and experimental rheumatology. 35, p. S71-S74Research output: Contribution to journal › Article › peer-review
11 Scopus citations -
Proteolysis by Granzyme B Enhances Presentation of Autoantigenic Peptidylarginine Deiminase 4 Epitopes in Rheumatoid Arthritis
Darrah, E., Kim, A., Zhang, X., Boronina, T., Cole, R. N., Fava, A., Giles, J. T., Bingham, C. O., Chalmers, M. J., Griffin, P. R., Sadegh-Nasseri, S. & Rosen, A., Jan 6 2017, In: Journal of proteome research. 16, 1, p. 355-365 11 p.Research output: Contribution to journal › Article › peer-review
Open Access12 Scopus citations -
Reply
Baer, A. N., Petri, M., Sohn, J., Rosen, A. & Casciola-Rosen, L., Mar 1 2017, In: Arthritis Care and Research. 69, 3, p. 454 1 p.Research output: Contribution to journal › Letter › peer-review
Open Access -
Reply
Shah, A. A., Rosen, A., Hummers, L. K., Wigley, F. M., Xu, G., Elledge, S. J. & Casciola-Rosen, L., Sep 2017, In: Arthritis and Rheumatology. 69, 9, p. 1915-1916 2 p.Research output: Contribution to journal › Letter › peer-review
Open Access -
2016
Aggregatibacter actinomycetemcomitans-induced hypercitrullination links periodontal infection to autoimmunity in rheumatoid arthritis
Konig, M. F., Abusleme, L., Reinholdt, J., Palmer, R. J., Teles, R. P., Sampson, K., Rosen, A., Nigrovic, P. A., Sokolove, J., Giles, J. T., Moutsopoulos, N. M. & Andrade, F., Dec 14 2016, In: Science translational medicine. 8, 369, 369ra176.Research output: Contribution to journal › Article › peer-review
Open Access208 Scopus citations -
Anti-Interferon-Inducible Protein 16 Antibodies Associate with Digital Gangrene in Patients with Scleroderma
McMahan, Z. H., Shah, A. A., Vaidya, D., Wigley, F. M., Rosen, A. & Casciola-Rosen, L., May 1 2016, In: Arthritis and Rheumatology. 68, 5, p. 1262-1271 10 p.Research output: Contribution to journal › Article › peer-review
Open Access11 Scopus citations -
Association of Acroosteolysis with Enhanced Osteoclastogenesis and Higher Blood Levels of Vascular Endothelial Growth Factor in Systemic Sclerosis
Park, J. K., Fava, A., Carrino, J., Del Grande, F., Rosen, A. & Boin, F., Jan 1 2016, In: Arthritis and Rheumatology. 68, 1, p. 201-209 9 p.Research output: Contribution to journal › Article › peer-review
Open Access12 Scopus citations -
Association of Antibodies to Interferon-Inducible Protein-16 with Markers of More Severe Disease in Primary Sjögren's Syndrome
Baer, A. N., Petri, M., Sohn, J., Rosen, A. & Casciola-Rosen, L., Feb 1 2016, In: Arthritis Care and Research. 68, 2, p. 254-260 7 p.Research output: Contribution to journal › Article › peer-review
Open Access20 Scopus citations -
Association of anti-peptidyl arginine deiminase antibodies with radiographic severity of rheumatoid arthritis in African Americans
CLEAR Investigators, Oct 22 2016, In: Arthritis Research and Therapy. 18, 1, 241.Research output: Contribution to journal › Article › peer-review
Open Access19 Scopus citations -
Autoantibodies as markers and possible mediators of scleroderma pathogenesis
Maurer, K. D. & Rosen, A., Jan 1 2016, Scleroderma: From Pathogenesis to Comprehensive Management. Springer International Publishing, p. 197-205 9 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter
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Autoantibodies in Rheumatoid Arthritis
Andrade, F., Darrah, E. D. & Rosen, A., Jan 1 2016, Kelley and Firestein's Textbook of Rheumatology: Volumes 1-2, Tenth Edition. Elsevier, Vol. 1. p. 831-845.e5Research output: Chapter in Book/Report/Conference proceeding › Chapter
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Autoantigens as Partners in Initiation and Propagation of Autoimmune Rheumatic Diseases
Rosen, A. & Casciola-Rosen, L., May 20 2016, In: Annual review of immunology. 34, p. 395-420 26 p.Research output: Contribution to journal › Review article › peer-review
19 Scopus citations -
Enrichment of Scleroderma Vascular Disease–Associated Autoantigens in Endothelial Lineage Cells
McMahan, Z. H., Cottrell, T. R., Wigley, F. M., Antiochos, B., Zambidis, E. T., Soon Park, T., Halushka, M. K., Gutierrez-Alamillo, L., Cimbro, R., Rosen, A. & Casciola-Rosen, L., Oct 1 2016, In: Arthritis and Rheumatology. 68, 10, p. 2540-2549 10 p.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Frequency of circulating topoisomerase-I-specific CD4 T cells predicts presence and progression of interstitial lung disease in scleroderma
Fava, A., Cimbro, R., Wigley, F. M., Liu, Q. R., Rosen, A. & Boin, F., May 4 2016, In: Arthritis Research and Therapy. 18, 1, 99.Research output: Contribution to journal › Article › peer-review
Open Access15 Scopus citations -
Improving the physical examination: In reply
Nelson, W. G., Rosen, A. & Pronovost, P. J., Oct 4 2016, In: JAMA - Journal of the American Medical Association. 316, 13, p. 1410-1411 2 p.Research output: Contribution to journal › Letter › peer-review
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PUF60: A prominent new target of the autoimmune response in dermatomyositis and Sjögren's syndrome
Fiorentino, D. F., Presby, M., Baer, A. N., Petri, M., Rieger, K. E., Soloski, M., Rosen, A., Mammen, A. L., Christopher-Stine, L. & Casciola-Rosen, L., Jun 2016, In: Annals of the rheumatic diseases. 75, 6, p. 1145-1151 7 p.Research output: Contribution to journal › Article › peer-review
Open Access20 Scopus citations