Research Output 1998 2017

2017

Cannabidiol Treatment for Refractory Seizures in Sturge-Weber Syndrome

Kaplan, E. H., Offermann, E. A., Sievers, J. W. & Comi, A. M. Jun 1 2017 In : Pediatric Neurology. 71, p. 18-23.e2

Research output: Research - peer-reviewArticle

Cannabidiol
Sturge-Weber Syndrome
Seizures
Epilepsy
Quality of Life
Sturge-Weber Syndrome
Neurocutaneous Syndromes
Tuberous Sclerosis
Neurofibromatosis 1
Epilepsy
2016

Leveraging a Sturge-Weber Gene Discovery: An Agenda for Future Research

Comi, A. M. , Sahin, M. , Hammill, A. , Kaplan, E. H. , Juhász, C. , North, P. , Ball, K. L. , Levin, A. V. , Cohen, B. , Morris, J. , Lo, W. , Roach, E. S. , Abreu, N. , Acosta, M. , Ball, K. L. , Berrocal, A. , Bischoff, J. , Brodie, J. , Burkhart, C. , Cohen, B. & 44 others Comi, A. M., Dymerska, G., Eckstein, D., Enriquez-Algeciras, M., Ewen, J., Fisher, B., Freedman, S., Germain-Lee, E., Geronemus, R., Gold, M., Gopal-Srivastava, R., Hammill, A., Hebert, A., Huang, L., Jampel, H., Juhász, C., Kaplan, E. H., Kaseka, M., Kirkorian, Y., Kossoff, E., Levin, A. V., Lin, D., Lo, W., Loeb, J., Marathe, K., Marchuk, D., Mead, A., Mellis, S., Morris, J., Murray, T., North, P., Phung, T., Pinto, A., Puttgen, K., Ratner, N., Reeve, J., Roach, S., Sahin, M., Swindell, C., Tseng, H., Tune, M., Wetzel-Strong, S., White, M. & Whittemore, V. May 1 2016 In : Pediatric Neurology. 58, p. 12-24 13 p.

Research output: Research - peer-reviewArticle

Sturge-Weber Syndrome
Genetic Association Studies
Research
Wine
Tissue Banks
2015

Anticonvulsant Efficacy in Sturge-Weber Syndrome

Kaplan, E. H., Kossoff, E. H., Bachur, C. D., Gholston, M., Hahn, J., Widlus, M. & Comi, A. M. Oct 30 2015 (Accepted/In press) In : Pediatric Neurology.

Research output: Research - peer-reviewArticle

Sturge-Weber Syndrome
Anticonvulsants
Seizures
etiracetam
Carbamazepine

Correction: Systemic Injection of CD34+ -Enriched Human Cord Blood Cells Modulates Poststroke Neural and Glial Response in a Sex-Dependent Manner in CD1 Mice (Stem Cells and Development (2015) 24, 1 (51-66))

Kadam, S., Chen, H., Markowitz, G. J., Raja, S., George, S., Verina, T., Shotwell, E., Loechelt, B., Johnston, M. V., Kamani, N., Fatemi, A. & Comi, A. M. Apr 1 2015 In : Stem Cells and Development. 24, 7, p. 916 1 p.

Research output: Research - peer-reviewArticle

Current Therapeutic Options in Sturge-Weber Syndrome

Comi, A. Dec 1 2015 In : Seminars in Pediatric Neurology. 22, 4, p. 295-301 7 p.

Research output: Research - peer-reviewArticle

Sturge-Weber Syndrome
Therapeutics
Seizures
Mutation
Vascular Malformations

Intellectual and adaptive functioning in Sturge-Weber Syndrome

Kavanaugh, B., Sreenivasan, A., Bachur, C., Papazoglou, A., Comi, A. & Zabel, T. A. May 3 2015 (Accepted/In press) In : Child Neuropsychology.

Research output: Research - peer-reviewArticle

Sturge-Weber Syndrome
Paresis
Seizures
Motor Skills
Young Adult

Partial hypopituitarism in patients with sturge-weber syndrome

Bachur, C. D., Comi, A. M. & Germain-Lee, E. L. Sep 1 2015 In : Pediatric Neurology. 53, 3, p. e5-e6

Research output: Research - peer-reviewArticle

Risk factors for attention and behavioral issues in pediatric sickle cell disease

Lance, E. I., Comi, A. M., Johnston, M. V., Casella, J. F. & Shapiro, B. K. Oct 11 2015 In : Clinical Pediatrics. 54, 11, p. 1087-1093 7 p.

Research output: Research - peer-reviewArticle

Sickle Cell Anemia
Pediatrics
Sickle Hemoglobin
Learning Disorders
Attention Deficit Disorder with Hyperactivity

Sturge-Weber syndrome

Comi, A. M. 2015 In : Handbook of Clinical Neurology. 132, p. 157-168 12 p.

Research output: Research - peer-reviewArticle

Sturge-Weber Syndrome
Therapeutics
Wine
Mutation
Brain

Systemic injection of CD34+-enriched human cord Blood cells modulates poststroke neural and glial response in a sex-dependent manner in CD1 mice

Kadam, S. D., Chen, H., Markowitz, G. J., Raja, S., George, S., Shotwell, E., Loechelt, B., Johnston, M. V., Kamani, N., Fatemi, A. & Comi, A. M. Jan 1 2015 In : Stem Cells and Development. 24, 1, p. 51-66 16 p.

Research output: Research - peer-reviewArticle

Fetal Blood
Neuroglia
Blood Cells
Stroke
Injections
2014

An overview of current and future treatment options for Sturge-Weber syndrome

Comi, A. M. Oct 1 2014 In : Expert Opinion on Orphan Drugs. 2, 10, p. 1015-1025 11 p.

Research output: Research - peer-reviewArticle

Sturge-Weber Syndrome
Therapeutics
Mutation
Nervous System
Blood Vessels

EEG evolution in Sturge-Weber syndrome

Kossoff, E. H., Bachur, C. D., Quain, A. M., Ewen, J. B. & Comi, A. M. 2014 In : Epilepsy Research. 108, 4, p. 816-819 4 p.

Research output: Research - peer-reviewArticle

Sturge-Weber Syndrome
Electroencephalography
Seizures
Nervous System

Preliminary reliability and validity of a battery for assessing functional skills in children with Sturge-Weber syndrome

Reidy, T. G., Suskauer, S. J., Bachur, C. D., McCulloch, C. E. & Comi, A. M. 2014 In : Child's Nervous System. 30, 12, p. 2027-2036 10 p.

Research output: Research - peer-reviewArticle

Sturge-Weber Syndrome
Reproducibility of Results
Outcome Assessment (Health Care)
Hand
Clinical Trials

Stimulant use in patients with sturge-weber syndrome: Safety and efficacy

Lance, E. I., Lanier, K. E., Zabel, T. A. & Comi, A. M. Nov 1 2014 In : Pediatric Neurology. 51, 5, p. 675-680 6 p.

Research output: Research - peer-reviewArticle

Sturge-Weber Syndrome
Safety
Vital Signs
Headache
Databases

Sturge-Weber Syndrome

Comi, A. M., Marchuk, D. A. & Pevsner, J. Nov 13 2014 Rosenberg's Molecular and Genetic Basis of Neurological and Psychiatric Disease: Fifth Edition. Elsevier Inc., p. 945-953 9 p.

Research output: ResearchChapter

Sturge-Weber Syndrome
Mutation
Capillary Malformations, Congenital, 1
Megalencephaly
Vascular Malformations
2013

A needle in a haystack: Sturge-Weber syndrome gene discovery

Comi, A. M., Marchuk, D. A. & Pevsner, J. Dec 2013 In : Pediatric Neurology. 49, 6, p. 391-392 2 p.

Research output: Research - peer-reviewArticle

Aspirin use in sturge-weber syndrome: Side effects and clinical outcomes

Lance, E. I., Sreenivasan, A. K., Zabel, T. A., Kossoff, E. H. & Comi, A. M. Feb 2013 In : Journal of Child Neurology. 28, 2, p. 213-218 6 p.

Research output: Research - peer-reviewArticle

Sturge-Weber Syndrome
Aspirin
Seizures
Brain
Nervous System

Case report of subdural hematoma in a patient with Sturge-Weber syndrome and literature review: questions and implications for therapy.

Lopez, J., Yeom, K. W., Comi, A. & Van Haren, K. May 2013 In : Journal of Child Neurology. 28, 5, p. 672-675 4 p.

Research output: Research - peer-reviewArticle

Sturge-Weber Syndrome
Subdural Hematoma
Therapeutics
Aspirin
Intracranial Hemorrhages

Corticospinal tract insult alters GABAergic circuitry in the mammalian spinal cord

Russ, J. B., Verina, T., Comer, J. D., Comi, A. M. & Kaltschmidt, J. A. Sep 25 2013 In : Frontiers in Neural Circuits. 7, SEP, 150

Research output: Research - peer-reviewArticle

Pyramidal Tracts
Spinal Cord
Interneurons
Wounds and Injuries
Reflex

Impact of trichostatin A and sodium valproate treatment on post-stroke neurogenesis and behavioral outcomes in immature mice

George, S., Kadam, S. D., Irving, N. D., Markowitz, G. J., Raja, S., Kwan, A., Tu, Y., Chen, H., Rohde, C., Smith, D. R. & Comi, A. M. Jul 13 2013 In : Frontiers in Cellular Neuroscience. JUL

Research output: Research - peer-reviewArticle

trichostatin A
Neurogenesis
Valproic Acid
Stroke
Dentate Gyrus

Importance of utilizing a sensitive free thyroxine assay in sturge-weber syndrome

Siddique, L., Sreenivasan, A., Comi, A. M. & Germain-Lee, E. L. Feb 2013 In : Journal of Child Neurology. 28, 2, p. 269-274 6 p.

Research output: Research - peer-reviewArticle

Sturge-Weber Syndrome
Hypothyroidism
Thyroxine
Anticonvulsants
Dialysis

Increased choroidal thickness in patients with Sturge-Weber syndrome

Arora, K. S., Quigley, H. A., Comi, A. M., Miller, R. B. & Jampel, H. D. Sep 2013 In : JAMA Ophthalmology. 131, 9, p. 1216-1219 4 p.

Research output: Research - peer-reviewArticle

Sturge-Weber Syndrome
Optical Coherence Tomography
Choroid
Hyperemia
Hemangioma

Ischemia-induced neuroinflammation is associated with disrupted development of oligodendrocyte progenitors in a model of periventricular leukomalacia

Falahati, S., Breu, M., Waickman, A. T., Phillips, A. W., Arauz, E. J., Snyder, S., Porambo, M., Goeral, K., Comi, A. M., Wilson, M. A., Johnston, M. V. & Fatemi, A. Jul 2013 In : Developmental Neuroscience. 35, 2-3, p. 182-196 15 p.

Research output: Research - peer-reviewArticle

Periventricular Leukomalacia
Oligodendroglia
Stem Cells
Ischemia
Ligation

Pluripotent possibilities: Human umbilical cord blood cell treatment after neonatal brain injury

Verina, T., Fatemi, A., Johnston, M. V. & Comi, A. M. May 2013 In : Pediatric Neurology. 48, 5, p. 346-354 9 p.

Research output: Research - peer-reviewArticle

Fetal Blood
Brain Injuries
Blood Cells
Therapeutics
Stem Cells

Sturge-weber syndrome

Bachur, C. D. & Comi, A. M. Oct 2013 In : Current Treatment Options in Neurology. 15, 5, p. 607-617 11 p.

Research output: Research - peer-reviewArticle

Sturge-Weber Syndrome
Seizures
Therapeutics
etiracetam
Paresis

Sturge-Weber syndrome and port-wine stains caused by somatic mutation in GNAQ

Shirley, M. D., Tang, H., Gallione, C. J., Baugher, J. D., Frelin, L. P., Cohen, B., North, P. E., Marchuk, D. A., Comi, A. M. & Pevsner, J. 2013 In : New England Journal of Medicine. 368, 21, p. 1971-1979 9 p.

Research output: Research - peer-reviewArticle

Sturge-Weber Syndrome
Port-Wine Stain
Mutation
Neurocutaneous Syndromes
Congenital, Hereditary, and Neonatal Diseases and Abnormalities

Urine vascular biomarkers in Sturge-Weber syndrome

Sreenivasan, A. K., Bachur, C. D., Lanier, K. E., Curatolo, A. S., Connors, S. M., Moses, M. A. & Comi, A. M. Jun 2013 In : Vascular Medicine. 18, 3, p. 122-128 7 p.

Research output: Research - peer-reviewArticle

Sturge-Weber Syndrome
Matrix Metalloproteinase 2
Blood Vessels
Biomarkers
Urine
2012
Sturge-Weber Syndrome
Oxidative Stress
Fibroblasts
Cell Proliferation
Proteins

Updates and future horizons on the understanding, diagnosis, and treatment of Sturge-Weber syndrome brain involvement

Lo, W., Marchuk, D. A., Ball, K. L., Juhász, C., Jordan, L. C., Ewen, J. B. & Comi, A. Mar 2012 In : Developmental Medicine and Child Neurology. 54, 3, p. 214-223 10 p.

Research output: Research - peer-reviewArticle

Sturge-Weber Syndrome
Brain
Therapeutics
Research
Direction compound
2011

Different effects of high- and low-dose phenobarbital on post-stroke seizure suppression and recovery in immature CD1 mice

Markowitz, G. J., Kadam, S. D., Smith, D. R., Johnston, M. V. & Comi, A. M. May 2011 In : Epilepsy Research. 94, 3, p. 138-148 11 p.

Research output: Research - peer-reviewArticle

Phenobarbital
Seizures
Stroke
Anticonvulsants
Weight Gain

Presentation, diagnosis, pathophysiology, and treatment of the neurological features of sturge-weber syndrome

Comi, A. M. Jul 2011 In : Neurologist. 17, 4, p. 179-184 6 p.

Research output: Research - peer-reviewArticle

Sturge-Weber Syndrome
Therapeutics
Capillary Malformations, Congenital, 1
Seizures
Brain

Survey of aspirin use in sturge-weber syndrome

Bay, M. J., Kossoff, E. H., Lehmann, C. U., Zabel, T. A. & Comi, A. M. Jun 2011 In : Journal of Child Neurology. 26, 6, p. 692-702 11 p.

Research output: Research - peer-reviewArticle

Sturge-Weber Syndrome
Aspirin
Surveys and Questionnaires
Seizures
Stroke
2010

A pilot study of the modified Atkins diet for Sturge-Weber syndrome

Kossoff, E. H., Borsage, J. L. & Comi, A. M. Dec 2010 In : Epilepsy Research. 92, 2-3, p. 240-243 4 p.

Research output: Research - peer-reviewArticle

Sturge-Weber Syndrome
Carbohydrate-Restricted Diet
Seizures
Ketogenic Diet
Ketosis

Behavioral and psychiatric features of Sturge-Weber syndrome

Turin, E., Grados, M. A., Tierney, E., Ferenc, L. M., Zabel, A. & Comi, A. M. Dec 2010 In : Journal of Nervous and Mental Disease. 198, 12, p. 905-913 9 p.

Research output: Research - peer-reviewArticle

Sturge-Weber Syndrome
Attention Deficit and Disruptive Behavior Disorders
Psychiatry
Seizures
Adjustment Disorders

Effect of a single application of pulsed dye laser treatment of port-wine birthmarks on intraocular pressure

Quan, S. Y., Comi, A. M., Parsa, C. F., Irving, N. D., Krakowski, A. C. & Cohen, B. A. 2010 In : Archives of Dermatology. 146, 9, p. 1015-1018 4 p.

Research output: Research - peer-reviewArticle

Dye Lasers
Wine
Intraocular Pressure
Therapeutics
Pressure
Comorbidity
Stroke
Neurons
Epilepsy
Hippocampus
Sturge-Weber Syndrome
Diffusion Magnetic Resonance Imaging
Young Adult
White Matter
Angiomatosis

Neonatal stroke in mice causes long-term changes in neuronal notch-2 expression that may contribute to prolonged injury

Albéri, L., Chi, Z., Kadam, S. D., Mulholland, J. D., Dawson, V. L., Gaiano, N. & Comi, A. M. Oct 2010 In : Stroke. 41, 10 SUPPL. 1

Research output: Research - peer-reviewArticle

Cell Death
Up-Regulation
Ischemia
Stroke
Oxygen

Neuropsychological features and risk factors in children with sturge-weber syndrome: Four case reports

Andrew Zabel, T., Reesman, J., Wodka, E. L., Gray, R., Suskauer, S. J., Turin, E., Ferenc, L. M., Lin, D. D. M., Kossoff, E. H. & Comi, A. M. Jul 2010 In : Clinical Neuropsychologist. 24, 5, p. 841-859 19 p.

Research output: Research - peer-reviewArticle

Syndrome
Risk Factors
Sturge-Weber Syndrome
Seizures
Impairment
Sturge-Weber Syndrome
Physical and Rehabilitation Medicine
Paresis
Seizures
Therapeutics

Stroke: Neonate vs: Adult

Comi, A. M. & Johnston, M. V. 2010 Encyclopedia of Neuroscience. Elsevier Ltd, p. 587-590 4 p.

Research output: ResearchChapter

Sturge-weber syndrome: Ear, nose, and throat issues and neurologic status

Irving, N. D., Lim, J. H., Cohen, B., Ferenc, L. M. & Comi, A. M. Oct 2010 In : Pediatric Neurology. 43, 4, p. 241-244 4 p.

Research output: Research - peer-reviewArticle

Sturge-Weber Syndrome
Pharynx
Nose
Nervous System
Ear

The pharmacokinetics of commonly used antiepileptic drugs in immature CD1 mice

Markowitz, G. J., Kadam, S. D., Boothe, D. M., Irving, N. D. & Comi, A. M. 2010 In : NeuroReport. 21, 6, p. 452-456 5 p.

Research output: Research - peer-reviewArticle

Anticonvulsants
Pharmacokinetics
Brain
Therapeutics
etiracetam
2009

An infantile-onset, severe, yet sporadic seizure pattern is common in Sturge-Weber syndrome

Kossoff, E. H., Ferenc, L. & Comi, A. M. Sep 2009 In : Epilepsia. 50, 9, p. 2154-2157 4 p.

Research output: Research - peer-reviewArticle

Sturge-Weber Syndrome
Seizures
Age of Onset

Chronic brain injury and behavioral impairments in a mouse model of term neonatal strokes

Kadam, S. D., Mulholland, J. D., Smith, D. R., Johnston, M. V. & Comi, A. M. Jan 30 2009 In : Behavioural Brain Research. 197, 1, p. 77-83 7 p.

Research output: Research - peer-reviewArticle

Chronic Brain Injury
Stroke
Brain Injuries
Ligation
Forelimb
Sturge-Weber Syndrome
Paresis
Neurologic Examination
Nervous System
Brain
Brain Injuries
Ligation
Seizures
Wounds and Injuries
Stroke

Poststroke subgranular and rostral subventricular zone proliferation in a mouse model of neonatal stroke

Kadam, S. D., Mulholland, J. D., McDonald, J. W. & Comi, A. M. Sep 2009 In : Journal of Neuroscience Research. 87, 12, p. 2653-2666 14 p.

Research output: Research - peer-reviewArticle

Lateral Ventricles
Stroke
Ischemia
Nestin
Bromodeoxyuridine

Sturge-Weber syndrome with cerebellar involvement

Smith Pearl, M., Abdalla, W. M. A., Lin, D. D. M., Comi, A. M., Boltshauser, E., Gailloud, P. & Huisman, T. A. G. M. Mar 2009 In : Journal of Neuroradiology. 36, 1, p. 57-60 4 p.

Research output: Research - peer-reviewArticle

Sturge-Weber Syndrome
Neurocutaneous Syndromes
Choroid
Hemangioma
Angiography