Andrew Jaffe

Assistant Professor

20092018
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DNA Methylation Medicine & Life Sciences
Schizophrenia Medicine & Life Sciences
Epigenomics Medicine & Life Sciences
Genes Medicine & Life Sciences
Brain Medicine & Life Sciences
Genome Medicine & Life Sciences
RNA Sequence Analysis Medicine & Life Sciences
Transcriptome Medicine & Life Sciences

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Research Output 2009 2018

Convergence of placenta biology and genetic risk for schizophrenia article

Ursini, G., Punzi, G., Chen, Q., Marenco, S., Robinson, J. F., Porcelli, A., Hamilton, E. G., Mitjans, M., Maddalena, G., Begemann, M., Seidel, J., Yanamori, H., Jaffe, A., Berman, K. F., Egan, M. F., Straub, R. E., Colantuoni, C., Blasi, G., Hashimoto, R., Rujescu, D. & 3 othersEhrenreich, H., Bertolino, A. & Weinberger, D., Jun 1 2018, In : Nature Medicine. 24, 6, p. 792-801 10 p.

Research output: Contribution to journalArticle

Genes
Set theory
Trajectories

Developmental and genetic regulation of the human cortex transcriptome illuminate schizophrenia pathogenesis

The BrainSeq Consortium, Aug 1 2018, In : Nature Neuroscience. 21, 8, p. 1117-1125 9 p.

Research output: Contribution to journalArticle

Medical Genetics
Transcriptome
Schizophrenia
Quantitative Trait Loci
RNA Sequence Analysis

Developmental effects of maternal smoking during pregnancy on the human frontal cortex transcriptome

Semick, S. A., Collado-Torres, L., Markunas, C. A., Shin, J. H., Deep-Soboslay, A., Tao, R., Huestis, M. A., Bierut, L. J., Maher, B., Johnson, E. O., Hyde, T., Weinberger, D. R., Hancock, D. B., Kleinman, J. & Jaffe, A., Jan 1 2018, (Accepted/In press) In : Molecular psychiatry.

Research output: Contribution to journalArticle

Frontal Lobe
Transcriptome
Smoking
Mothers
Pregnancy

GAD1 alternative transcripts and DNA methylation in human prefrontal cortex and hippocampus in brain development, schizophrenia

Tao, R., Davis, K. N., Li, C., Shin, J. H., Gao, Y., Jaffe, A., Gondré-Lewis, M. C., Weinberger, D., Kleinman, J. E. & Hyde, T., Jun 1 2018, In : Molecular Psychiatry. 23, 6, p. 1496-1505 10 p.

Research output: Contribution to journalArticle

DNA Methylation
Prefrontal Cortex
Hippocampus
Schizophrenia
gamma-Aminobutyric Acid

Investigating the neuroimmunogenic architecture of schizophrenia

Birnbaum, R., Jaffe, A., Chen, Q., Shin, J. H., Kleinman, J., Hyde, T. & Weinberger, D., May 1 2018, In : Molecular Psychiatry. 23, 5, p. 1251-1260 10 p.

Research output: Contribution to journalArticle

Schizophrenia
Prefrontal Cortex
Genes
Immune System
Hippocampus