Ana De Jesus-Acosta

2023

A platform trial of neoadjuvant and adjuvant antitumor vaccination alone or in combination with PD-1 antagonist and CD137 agonist antibodies in patients with resectable pancreatic adenocarcinoma

Heumann, T., Judkins, C., Li, K., Lim, S. J., Hoare, J., Parkinson, R., Cao, H., Zhang, T., Gai, J., Celiker, B., Zhu, Q., McPhaul, T., Durham, J., Purtell, K., Klein, R., Laheru, D., De Jesus-Acosta, A., Le, D. T., Narang, A., Anders, R., & 9 othersBurkhart, R., Burns, W., Soares, K., Wolfgang, C., Thompson, E., Jaffee, E., Wang, H., He, J. & Zheng, L., Dec 2023, In: Nature communications. 14, 1, 3650.

Research output: Contribution to journal › Article › peer-review

Open Access

Clinical outcomes of liposomal irinotecan in advanced pancreatic adenocarcinoma patients previously treated with conventional irinotecan-based chemotherapy: a real-world study

Gupta, A., De Jesus-Acosta, A., Zheng, L., Lee, V., Kamel, I., Le, D., Pishvaian, M. & Laheru, D., 2023, In: Frontiers in Oncology. 13, 1250136.

Research output: Contribution to journal › Article › peer-review

Open Access

Solid Organ Transplantation Is Associated with an Increased Rate of Mismatch Repair Deficiency and PIK3CA Mutations in Colorectal Cancer

Christenson, E. S., Lee, V., Wang, H., Yarchoan, M., De Jesus-Acosta, A., Azad, N., Gurakar, A., Lin, M. T., Le, D. T., Brennan, D. C., Jaffee, E. M. & Bever, K., Jan 2023, In: Current Oncology. 30, 1, p. 75-84 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2022

Genetics of Pancreatic Neuroendocrine Tumors

Mohindroo, C., McAllister, F. & De Jesus-Acosta, A., Oct 2022, In: Hematology/Oncology Clinics of North America. 36, 5, p. 1033-1051 19 p.

Research output: Contribution to journal › Review article › peer-review

Health-related quality of life in patients treated with pembrolizumab for microsatellite instability–high/mismatch repair–deficient advanced solid tumours: Results from the KEYNOTE-158 study

Maio, M., Amonkar, M. M., Norquist, J. M., Ascierto, P. A., Manzyuk, L., Motola-Kuba, D., Penel, N., Cassier, P. A., Bariani, G. M., De Jesus Acosta, A., Doi, T., Longo, F., Miller, W. H., Oh, D. Y., Gottfried, M., Wang, R., Norwood, K. & Marabelle, A., Jul 2022, In: European Journal of Cancer. 169, p. 188-197 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Health-related quality of life with pembrolizumab monotherapy in patients with previously treated advanced microsatellite instability high/mismatch repair deficient endometrial cancer in the KEYNOTE-158 study

O'Malley, D. M., Bariani, G. M., Cassier, P. A., Marabelle, A., Hansen, A. R., De Jesus Acosta, A., Miller, W. H., Safra, T., Italiano, A., Mileshkin, L., Amonkar, M., Yao, L., Jin, F., Norwood, K. & Maio, M., Aug 2022, In: Gynecologic oncology. 166, 2, p. 245-253 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

High local failure rates despite high margin-negative resection rates in a cohort of borderline resectable and locally advanced pancreatic cancer patients treated with stereotactic body radiation therapy following multi-agent chemotherapy

Hill, C., Sehgal, S., Fu, W., Hu, C., Reddy, A., Thompson, E., Hacker-Prietz, A., Le, D., De Jesus-Acosta, A., Lee, V., Zheng, L., Laheru, D. A., Burns, W., Weiss, M., Wolfgang, C., He, J., Herman, J. M., Meyer, J. & Narang, A., Apr 2022, In: Cancer medicine. 11, 7, p. 1659-1668 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Neoadjuvant Stereotactic Body Radiotherapy After Upfront Chemotherapy Improves Pathologic Outcomes Compared With Chemotherapy Alone for Patients With Borderline Resectable or Locally Advanced Pancreatic Adenocarcinoma Without Increasing Perioperative Toxicity

Hill, C. S., Rosati, L. M., Hu, C., Fu, W., Sehgal, S., Hacker-Prietz, A., Wolfgang, C. L., Weiss, M. J., Burkhart, R. A., Hruban, R. H., De Jesus-Acosta, A., Le, D. T., Zheng, L., Laheru, D. A., He, J., Narang, A. K. & Herman, J. M., Apr 2022, In: Annals of surgical oncology. 29, 4, p. 2456-2468 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Pembrolizumab in microsatellite instability high or mismatch repair deficient cancers: updated analysis from the phase II KEYNOTE-158 study

Maio, M., Ascierto, P. A., Manzyuk, L., Motola-Kuba, D., Penel, N., Cassier, P. A., Bariani, G. M., De Jesus Acosta, A., Doi, T., Longo, F., Miller, W. H., Oh, D. Y., Gottfried, M., Xu, L., Jin, F., Norwood, K. & Marabelle, A., Sep 2022, In: Annals of Oncology. 33, 9, p. 929-938 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Pembrolizumab in Patients With Microsatellite Instability–High Advanced Endometrial Cancer: Results From the KEYNOTE-158 Study

O’Malley, D. M., Bariani, G. M., Cassier, P. A., Marabelle, A., Hansen, A. R., De Jesus Acosta, A., Miller, W. H., Safra, T., Italiano, A., Mileshkin, L., Xu, L., Jin, F., Norwood, K. & Maio, M., Mar 1 2022, In: Journal of Clinical Oncology. 40, 7, p. 752-761 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Post-radiation neutrophil-to-lymphocyte ratio is a prognostic marker in patients with localized pancreatic adenocarcinoma treated with anti-PD-1 antibody and stereotactic body radiation therapy

Reddy, A. V., Hill, C. S., Sehgal, S., Zheng, L., He, J., Laheru, D. A., De Jesus-Acosta, A., Herman, J. M., Meyer, J. & Narang, A. K., Jun 2022, In: Radiation Oncology Journal. 40, 2, p. 111-119 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

The Evolving Paradigm of Germline Testing in Pancreatic Ductal Adenocarcinoma and Implications for Clinical Practice

Mohindroo, C., De Jesus-Acosta, A., Yurgelun, M. B., Maitra, A., Mork, M. & McAllister, F., Sep 2022, In: Surgical Pathology Clinics. 15, 3, p. 491-502 12 p.

Research output: Contribution to journal › Review article › peer-review

2021

A Rare Case of Subcutaneous Insulin Resistance Presumed to be due to Paraneoplastic Process in Pancreatic Adenocarcinoma

Chae, K., Perlman, J., Fransman, R. B., Wolfgang, C. L., De Jesus-Acosta, A. & Mathioudakis, N., Nov 1 2021, In: AACE Clinical Case Reports. 7, 6, p. 379-382 4 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Challenges of the current precision medicine approach for pancreatic cancer: A single institution experience between 2013 and 2017

Ding, D., Javed, A. A., Cunningham, D., Teinor, J., Wright, M., Javed, Z. N., Wilt, C., Parish, L., Hodgin, M., Ryan, A., Judkins, C., McIntyre, K., Klein, R., Azad, N., Lee, V., Donehower, R., De Jesus-Acosta, A., Murphy, A., Le, D. T., Shin, E. J., & 30 othersLennon, A. M., Khashab, M., Singh, V., Klein, A. P., Roberts, N. J., Hacker-Prietz, A., Manos, L., Walsh, C., Groshek, L., Brown, C., Yuan, C., Blair, A. B., Groot, V., Gemenetzis, G., Yu, J., Weiss, M. J., Burkhart, R. A., Burns, W. R., He, J., Cameron, J. L., Narang, A., Zaheer, A., Fishman, E. K., Thompson, E. D., Anders, R., Hruban, R. H., Jaffee, E., Wolfgang, C. L., Zheng, L. & Laheru, D. A., Jan 28 2021, In: Cancer Letters. 497, p. 221-228 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Scopus citations

Combining tumor deposits with the number of lymph node metastases to improve the prognostic accuracy in stage III colon cancer: a post hoc analysis of the CALGB/SWOG 80702 phase III study (Alliance)^☆

Cohen, R., Shi, Q., Meyers, J., Jin, Z., Svrcek, M., Fuchs, C., Couture, F., Kuebler, P., Ciombor, K. K., Bendell, J., De Jesus-Acosta, A., Kumar, P., Lewis, D., Tan, B., Bertagnolli, M. M., Philip, P., Blanke, C., O'Reilly, E. M., Shields, A. & Meyerhardt, J. A., Oct 2021, In: Annals of Oncology. 32, 10, p. 1267-1275 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Prognostic Implications of the Immune Tumor Microenvironment in Patients with Pancreatic and Gastrointestinal Neuroendocrine Tumors

Baretti, M., Zhu, Q., Zahurak, M., Bhaijee, F., Xu, H., Engle, E. L., Kotte, A., Pawlik, T. M., Anders, R. A. & De Jesus-Acosta, A., 2021, In: Pancreas. 50, 5, p. 719-726 8 p.

Research output: Contribution to journal › Article › peer-review

Survival Outcomes of Adjuvant Chemotherapy Combined with Radiation Versus Chemotherapy Alone after Pancreatectomy for Distal Pancreatic Adenocarcinoma: A Single-Institution Experience

Batukbhai, B., Herman, J. M., Zahurak, M., Laheru, D. A., Le, D. T., Wolfgang, C. L., Zheng, L. & De Jesus-Acosta, A., 2021, In: Pancreas. 50, 1, p. 64-70 7 p.

Research output: Contribution to journal › Article › peer-review

Usefulness of an immunohistochemical score in advanced pancreatic neuroendocrine tumors treated with CAPTEM or everolimus

Viúdez, A., Crespo, G., Gómez Dorronsoro, M. L., Arozarena, I., Marín-Méndez, J. J., Custodio, A., Benavent, M., Goñi, S., García-Paredes, B., Hernando, J., Durantez, M., Alonso, V., Riesco, M. D. C., López, C., Jiménez-Fonseca, P., San Vicente, B. L., González-Borja, I., Sevilla, I., Hernández-Garcia, I., Carmona-Bayonas, A., & 7 othersCapdevila, J., Pérez-Sanz, J., García-Carbonero, R., Pérez-Ricarte, L., Llanos, M., Vera, R. & De Jesús Acosta, A., Jan 2021, In: Pancreatology. 21, 1, p. 215-223 9 p.

Research output: Contribution to journal › Article › peer-review

Vaccine-induced intratumoral lymphoid aggregates correlate with survival following treatment with a neoadjuvant and adjuvant vaccine in patients with resectable pancreatic adenocarcinoma

Zheng, L., Ding, D., Edil, B. H., Judkins, C., Durham, J. N., Thomas, D. L., Bever, K. M., Mo, G., Solt, S. E., Hoare, J. A., Bhattacharya, R., Zhu, Q., Osipov, A., Onner, B., Purtell, K. A., Cai, H., Parkinson, R., Hacker-Prietz, A., Herman, J. M., Le, D. T., & 17 othersAzad, N. S., de Jesus-Acosta, A. M. C., Blair, A. B., Kim, V., Soares, K. C., Manos, L., Cameron, J. L., Makary, M. A., Weiss, M. J., Schulick, R. D., He, J., Wolfgang, C. L., Thompson, E. D., Anders, R. A., Sugar, E., Jaffee, E. M. & Laheru, D. A., Mar 1 2021, In: Clinical Cancer Research. 27, 5, p. 1278-1286 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Scopus citations

2020

An exploratory study of metformin with or without rapamycin as maintenance therapy after induction chemotherapy in patients with metastatic pancreatic adenocarcinoma

Bever, K. M., Borazanci, E. H., Thompson, E. A., Durham, J. N., Pinero, K., Jameson, G. S., Vrana, A., Liu, M., Wilt, C., Wu, A. A., Fu, W., Wang, H., Yin, Y., Leal, J. P., de Jesus-Acosta, A., Zheng, L., Laheru, D. A., von Hoff, D. D., Jaffee, E. M., Powell, J. D., & 1 othersLe, D. T., May 26 2020, In: Oncotarget. 11, 21, p. 1929-1941 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

A phase 2 study of GVAX colon vaccine with cyclophosphamide and pembrolizumab in patients with mismatch repair proficient advanced colorectal cancer

Yarchoan, M., Huang, C. Y., Zhu, Q., Ferguson, A. K., Durham, J. N., Anders, R. A., Thompson, E. D., Rozich, N. S., Thomas, D. L., Nauroth, J. M., Rodriguez, C., Osipov, A., De Jesus-Acosta, A., Le, D. T., Murphy, A. G., Laheru, D., Donehower, R. C., Jaffee, E. M., Zheng, L. & Azad, N. S., Feb 1 2020, In: Cancer medicine. 9, 4, p. 1485-1494 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

9 Scopus citations

Efficacy of pembrolizumab in patients with noncolorectal high microsatellite instability/ mismatch repair–deficient cancer: Results from the phase II KEYNOTE-158 study

Marabelle, A., Le, D. T., Ascierto, P. A., Di Giacomo, A. M., de Jesus-Acosta, A., Delord, J. P., Geva, R., Gottfried, M., Penel, N., Hansen, A. R., Piha-Paul, S. A., Doi, T., Gao, B., Chung, H. C., Lopez-Martin, J., Bang, Y. J., Frommer, R. S., Shah, M., Ghori, R., Joe, A. K., & 2 othersPruitt, S. K. & Diaz, L. A., 2020, In: Journal of Clinical Oncology. 38, 1, p. 1-10 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

317 Scopus citations

Phase 2 study of vismodegib, a hedgehog inhibitor, combined with gemcitabine and nab-paclitaxel in patients with untreated metastatic pancreatic adenocarcinoma

De Jesus-Acosta, A., Sugar, E. A., O’Dwyer, P. J., Ramanathan, R. K., Von Hoff, D. D., Rasheed, Z., Zheng, L., Begum, A., Anders, R., Maitra, A., McAllister, F., Rajeshkumar, N. V., Yabuuchi, S., de Wilde, R. F., Batukbhai, B., Sahin, I. & Laheru, D. A., Feb 18 2020, In: British journal of cancer. 122, 4, p. 498-505 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

25 Scopus citations

2019

Carcinoma of the Pancreas

De Jesus-Acosta, A., Narang, A., Mauro, L., Herman, J., Jaffee, E. M. & Laheru, D. A., Jan 1 2019, Abeloff’s Clinical Oncology. Elsevier, p. 1342-1360.e7

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Effect of Gemcitabine and nab-Paclitaxel with or Without Hydroxychloroquine on Patients with Advanced Pancreatic Cancer: A Phase 2 Randomized Clinical Trial

Karasic, T. B., O'Hara, M. H., Loaiza-Bonilla, A., Reiss, K. A., Teitelbaum, U. R., Borazanci, E., De Jesus-Acosta, A., Redlinger, C., Burrell, J. A., Laheru, D. A., Von Hoff, D. D., Amaravadi, R. K., Drebin, J. A. & O'Dwyer, P. J., Jul 2019, In: JAMA Oncology. 5, 7, p. 993-998 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

54 Scopus citations

Molecular characterization and treatment of pancreatic neuroendocrine tumors

de Jesus-Acosta, A. M. C., Dec 2019, In: ONCOLOGY (United States). 33, 12, p. 500-502 3 p.

Research output: Contribution to journal › Comment/debate › peer-review

Programmed cell death ligand-1 (PD-L1) and CD8 expression profiling identify an immunologic subtype of pancreatic ductal adenocarcinomas with favorable survival

Danilova, L., Ho, W. J., Zhu, Q., Vithayathil, T., De Jesus-Acosta, A., Azad, N. S., Laheru, D. A., Fertig, E. J., Anders, R., Jaffee, E. M. & Yarchoan, M., Jun 2019, In: Cancer Immunology Research. 7, 6, p. 886-895 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

28 Scopus citations

The Molecular and Clinical Landscape of Pancreatic Neuroendocrine Tumors

Batukbhai, B. D. O. & De Jesus-Acosta, A., Jan 1 2019, In: Pancreas. 48, 1, p. 9-21 13 p.

Research output: Contribution to journal › Review article › peer-review

8 Scopus citations

The Significance of Ascites in Patients with Pancreatic Ductal Adenocarcinoma: A Case-Control Study

Baretti, M., Pulluri, B., Tsai, H. L., Blackford, A. L., Wolfgang, C. L., Laheru, D., Zheng, L., Herman, J., Le, D. T., Narang, A. K. & De Jesus-Acosta, A., Apr 1 2019, In: Pancreas. 48, 4, p. 585-589 5 p.

Research output: Contribution to journal › Article › peer-review

Open Access

3 Scopus citations

2018

A phase I trial of a guadecitabine (SGI-110) and irinotecan in metastatic colorectal cancer patients previously exposed to irinotecan

Lee, V., Wang, J., Zahurak, M., Gootjes, E., Verheul, H. M., Parkinson, R., Kerner, Z., Sharma, A., Rosner, G., De Jesus-Acosta, A., Laheru, D., Le, D. T., Oganesian, A., Lilly, E., Brown, T., Jones, P., Baylin, S., Ahuja, N. & Azad, N., Dec 15 2018, In: Clinical Cancer Research. 24, 24, p. 6160-6167 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

20 Scopus citations

Diagnostic intervals and pancreatic ductal adenocarcinoma (PDAC) resectability: A single-center retrospective analysis

Deshwar, A. B., Sugar, E., Torto, D., De Jesus-Acosta, A., Weiss, M. J., Wolfgang, C. L., Le, D., He, J., Burkhart, R., Zheng, L., Laheru, D. & Yarchoan, M., Feb 2018, In: Annals of Pancreatic Cancer. 1

Research output: Contribution to journal › Review article › peer-review

Multiplex Proximity Ligation Assay to Identify Potential Prognostic Biomarkers for Improved Survival in Locally Advanced Pancreatic Cancer Patients Treated With Stereotactic Body Radiation Therapy

Rao, A. D., Liu, Y., von Eyben, R., Hsu, C. C., Hu, C., Rosati, L. M., Parekh, A., Ng, K., Hacker-Prietz, A., Zheng, L., Pawlik, T. M., Laheru, D. A., Jaffee, E. M., Weiss, M. J., Le, D. T., Hruban, R. H., De Jesus-Acosta, A., Wolfgang, C. L., Narang, A. K., Chang, D. T., & 2 othersKoong, A. C. & Herman, J., Feb 1 2018, In: International Journal of Radiation Oncology Biology Physics. 100, 2, p. 486-489 4 p.

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

2017

Correction to "A new immunohistochemistry prognostic score (IPS) for recurrence and survival in resected pancreatic neuroendocrine tumors (PanNET)" [Oncotarget. 2016; 7(18):25950-61]. doi: 10.18632/oncotarget.7436

Viúdez, A., Carvalho, F. L. F., Maleki, Z., Zahurak, M., Laheru, D., Stark, A., Azad, N. S., Wolfgang, C., Baylin, S., Herman, J. G. & De Jesus-Acosta, A. D., 2017, In: Oncotarget. 8, 11, p. 18617 1 p.

Research output: Contribution to journal › Comment/debate › peer-review

Open Access

1 Scopus citations

Long-term survival benefit of upfront chemotherapy in patients with newly diagnosed borderline resectable pancreatic cancer

Shrestha, B., Sun, Y., Faisal, F., Kim, V., Soares, K., Blair, A., Herman, J. M., Narang, A., Dholakia, A. S., Rosati, L., Hacker-Prietz, A., Chen, L., Laheru, D. A., De Jesus-Acosta, A., Le, D. T., Donehower, R., Azad, N., Diaz, L. A., Murphy, A., Lee, V., & 11 othersFishman, E. K., Hruban, R. H., Liang, T., Cameron, J. L., Makary, M., Weiss, M. J., Ahuja, N., He, J., Wolfgang, C. L., Huang, C. Y. & Zheng, L., Jul 2017, In: Cancer medicine. 6, 7, p. 1552-1562 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

12 Scopus citations

Olaparib in combination with irinotecan, cisplatin, and mitomycin c in patients with advanced pancreatic cancer

Yarchoan, M., Myzak, M. C., Johnson, B. A., De Jesus-Acosta, A. D., Le, D. T., Jaffee, E. M., Azad, N. S., Donehower, R. C., Zheng, L., Oberstein, P. E., Fine, R. L., Laheru, D. A. & Goggins, M., 2017, In: Oncotarget. 8, 27, p. 44073-44081 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

35 Scopus citations

The extracellular matrix and focal adhesion kinase signaling regulate cancer stem cell function in pancreatic ductal adenocarcinoma

Begum, A., Ewachiw, T., Jung, C., Huang, A., Norberg, K. J., Marchionni, L., McMillan, R., Penchev, V., Rajeshkumar, N. V., Maitra, A., Wood, L., Wang, C., Wolfgang, C., Dejesus-Acosta, A., Laheru, D., Shapiro, I. M., Padval, M., Pachter, J. A., Weaver, D. T., Rasheed, Z. A., & 1 othersMatsui, W., Jul 2017, In: PloS one. 12, 7, e0180181.

Research output: Contribution to journal › Article › peer-review

Open Access

34 Scopus citations

2016

A new immunohistochemistry prognostic score (IPS) for recurrence and survival in resected pancreatic neuroendocrine tumors (PanNET)

Viúdez, A., Carvalho, F. L. F., Maleki, Z., Zahurak, M., Laheru, D., Stark, A., Azad, N. Z., Wolfgang, C. L., Baylin, S., Herman, J. G. & De Jesus-Acosta, A., May 1 2016, In: Oncotarget. 7, 18, p. 24950-24961 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

14 Scopus citations

Longer course of induction chemotherapy followed by chemoradiation favors better survival outcomes for patients with locally advanced pancreatic cancer

Faisal, F., Tsai, H. L., Blackford, A., Olino, K., Xia, C., De Jesus-Acosta, A., Le, D. T., Cosgrove, D., Azad, N., Rasheed, Z., Diaz, L. A., Donehower, R., Laheru, D., Hruban, R. H., Fishman, E. K., Edil, B. H., Schulick, R., Wolfgang, C., Herman, J. & Zheng, L., 2016, In: American Journal of Clinical Oncology: Cancer Clinical Trials. 39, 1, p. 18-26 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

12 Scopus citations

Pancreatic neuroendocrine tumors: Challenges in an underestimated disease

Viúdez, A., De Jesus-Acosta, A., Carvalho, F. L., Vera, R., Martín-Algarra, S. & Ramírez, N., May 1 2016, In: Critical Reviews in Oncology/Hematology. 101, p. 193-206 14 p.

Research output: Contribution to journal › Review article › peer-review

14 Scopus citations

2015

Efficacy of platinum chemotherapy agents in the adjuvant setting for adenosquamous carcinoma of the pancreas

Wild, A. T., Dholakia, A. S., Fan, K. Y., Kumar, R., Moningi, S., Rosati, L. M., Laheru, D. A., Zheng, L., De Jesus-Acosta, A., Ellsworth, S. G., Hacker-Prietz, A., Voong, K. R., Tran, P. T., Hruban, R. H., Pawlik, T. M., Wolfgang, C. L. & Herman, J., 2015, In: Journal of Gastrointestinal Oncology. 6, 2, p. 115-125 11 p.

Research output: Contribution to journal › Article › peer-review

15 Scopus citations

Erratum to Depletion of Carcinoma-Associated Fibroblasts and Fibrosis Induces Immunosuppression and Accelerates Pancreas Cancer with Reduced Survival [Cancer Cell 25, 719-734; (2014)]

Özdemir, B. C., Pentcheva-Hoang, T., Carstens, J. L., Zheng, X., Wu, C. C., Simpson, T. R., Laklai, H., Sugimoto, H., Kahlert, C., Novitskiy, S. V., De Jesus-Acosta, A., Sharma, P., Heidari, P., Mahmood, U., Chin, L., Moses, H. L., Weaver, V. M., Maitra, A., Allison, J. P., LeBleu, V. S., & 1 othersKalluri, R., Dec 14 2015, In: Cancer cell. 28, 6, p. 831-833 3 p.

Research output: Contribution to journal › Comment/debate › peer-review

Open Access

62 Scopus citations

Resected pancreatic ductal adenocarcinomas with recurrence limited in lung have a significantly better prognosis than those with other recurrence patterns

Wangjam, T., Zhang, Z., Zhou, X. C., Lyer, L., Faisal, F., Soares, K. C., Fishman, E., Hruban, R. H., Herman, J. M., Laheru, D., Weiss, M., Li, M., De Jesus-Acosta, A., Wolfgang, C. L. & Zheng, L., 2015, In: Oncotarget. 6, 34, p. 36903-36910 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

35 Scopus citations

The prognostic value of stroma in pancreatic cancer in patients receiving adjuvant therapy

Bever, K. M., Sugar, E. A., Bigelow, E., Sharma, R., Laheru, D., Wolfgang, C. L., Jaffee, E. M., Anders, R. A., De Jesus-Acosta, A. & Zheng, L., Apr 1 2015, In: HPB. 17, 4, p. 292-298 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

44 Scopus citations

The Role of Stereotactic Body Radiation Therapy for Pancreatic Cancer: A Single-Institution Experience

Moningi, S., Dholakia, A. S., Raman, S. P., Blackford, A., Cameron, J. L., Le, D. T., De Jesus-Acosta, A. M. C., Hacker-Prietz, A., Rosati, L. M., Assadi, R. K., Dipasquale, S., Pawlik, T. M., Zheng, L., Weiss, M. J., Laheru, D. A., Wolfgang, C. L. & Herman, J. M., Jul 8 2015, In: Annals of surgical oncology. 22, 7, p. 2352-2358 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

103 Scopus citations

2014

A phase II study of the gamma secretase inhibitor RO4929097 in patients with previously treated metastatic pancreatic adenocarcinoma

De Jesus-Acosta, A., Laheru, D., Maitra, A., Arcaroli, J., Rudek, M. A., Dasari, A., Blatchford, P. J., Quackenbush, K. & Messersmith, W., Aug 2014, In: Investigational New Drugs. 32, 4, p. 739-745 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

77 Scopus citations

Baseline hemoglobin-A1c impacts clinical outcomes in patients with pancreatic cancer

Fan, K. Y., Dholakia, A. S., Wild, A. T., Su, Z., Hacker-Prietz, A., Kumar, R., Hodgin, M., Hsu, C. C., Le, D. T., De Jesus-Acosta, A., Diaz, L. A., Laheru, D. A., Hruban, R. H., Fishman, E. K., Brown, T. D., Pawlik, T. M., Wolfgang, C. L., Tran, P. T. & Herman, J. M., Jan 1 2014, In: JNCCN Journal of the National Comprehensive Cancer Network. 12, 1, p. 50-57 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

9 Scopus citations

dCK expression correlates with 5-fluorouracil efficacy and HuR cytoplasmic expression in pancreatic cancer: A dual-institutional follow-up with the RTOG 9704 trial

McAllister, F., Pineda, D. M., Jimbo, M., Lal, S., Burkhart, R. A., Moughan, J., Winter, K. A., Abdelmohsen, K., Gorospe, M., De Jesus Acosta, A., Lankapalli, R. H., Winter, J. M., Yeo, C. J., Witkiewicz, A. K., Iacobuzio-Donahue, C. A., Laheru, D. & Brody, J. R., Jun 2014, In: Cancer Biology and Therapy. 15, 6, p. 688-698 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

29 Scopus citations

Depletion of carcinoma-associated fibroblasts and fibrosis induces immunosuppression and accelerates pancreas cancer with reduced survival

Özdemir, B. C., Pentcheva-Hoang, T., Carstens, J. L., Zheng, X., Wu, C. C., Simpson, T. R., Laklai, H., Sugimoto, H., Kahlert, C., Novitskiy, S. V., DeJesus-Acosta, A., Sharma, P., Heidari, P., Mahmood, U., Chin, L., Moses, H. L., Weaver, V. M., Maitra, A., Allison, J. P., LeBleu, V. S., & 1 othersKalluri, R., Jun 16 2014, In: Cancer cell. 25, 6, p. 719-734 16 p.

Research output: Contribution to journal › Article › peer-review

Open Access

1062 Scopus citations

PAK1 mediates pancreatic cancer cell migration and resistance to MET inhibition

Zhou, W., Jubb, A. M., Lyle, K., Xiao, Q., Ong, C. C., Desai, R., Fu, L., Gnad, F., Song, Q., Haverty, P. M., Aust, D., Grützmann, R., Romero, M., Totpal, K., Neve, R. M., Yan, Y., Forrest, W. F., Wang, Y., Raja, R., Pilarsky, C., & 8 othersDe Jesus-Acosta, A., Belvin, M., Friedman, L. S., Merchant, M., Jaffee, E. M., Zheng, L., Koeppen, H. & Hoeflich, K. P., Dec 1 2014, In: Journal of Pathology. 234, 4, p. 502-513 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

32 Scopus citations

2013

Phase 2 study of erlotinib combined with adjuvant chemoradiation and chemotherapy in patients with resectable pancreatic cancer

Herman, J. M., Fan, K. Y., Wild, A. T., Hacker-Prietz, A., Wood, L. D., Blackford, A. L., Ellsworth, S., Zheng, L., Le, D. T., De Jesus-Acosta, A., Hidalgo, M., Donehower, R. C., Schulick, R. D., Edil, B. H., Choti, M. A., Hruban, R. H., Pawlik, T. M., Cameron, J. L., Laheru, D. A. & Wolfgang, C. L., Jul 15 2013, In: International Journal of Radiation Oncology Biology Physics. 86, 4, p. 678-685 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

25 Scopus citations

Ana De Jesus-Acosta

Research output

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