Research output per year
Research output per year
- 44 results
Search results
-
2023
Bacterial meningitis in the early postnatal mouse studied at single-cell resolution
Wang, J., Rattner, A. & Nathans, J., 2023, In: eLife. 12, e86130.Research output: Contribution to journal › Article › peer-review
Open Access -
Normal and Sjogren's syndrome models of the murine lacrimal gland studied at single-cell resolution
Rattner, A., Heng, J. S., Winer, B. L., Goff, L. A. & Nathans, J., 2023, In: Proceedings of the National Academy of Sciences of the United States of America. 120, 42, e2311983120.Research output: Contribution to journal › Article › peer-review
Open Access -
2022
Signaling Pathways in Neurovascular Development
Rattner, A., Wang, Y. & Nathans, J., Jul 2022, In: Annual review of neuroscience. 45, p. 87-108 22 p.Research output: Contribution to journal › Review article › peer-review
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2021
A transcriptome atlas of the mouse iris at single-cell resolution defines cell types and the genomic response to pupil dilation
Wang, J., Rattner, A. & Nathans, J., Nov 2021, In: eLife. 10, e73477.Research output: Contribution to journal › Article › peer-review
Open Access -
2020
Developmental, cellular, and behavioral phenotypes in a mouse model of congenital hypoplasia of the dentate gyrus
Rattner, A., Terrillion, C. E., Jou, C., Kleven, T., Hu, S. F., Williams, J., Hou, Z., Aggarwal, M., Mori, S., Shin, G., Goff, L. A., Witter, M. P., Pletnikov, M., Fenton, A. A. & Nathans, J., Oct 2020, In: eLife. 9, p. 1-30 30 p., e62766.Research output: Contribution to journal › Article › peer-review
Open Access -
2019
Beta-catenin signaling regulates barrier- specific gene expression in circumventricular organ and ocular vasculatures
Wang, Y., Sabbagh, M. F., Gu, X., Rattner, A., Williams, J. & Nathans, J., Apr 2019, In: eLife. 8, e43257.Research output: Contribution to journal › Article › peer-review
Open Access21 Scopus citations -
Hypoxia tolerance in the Norrin-deficient retina and the chronically hypoxic brain studied at single-cell resolution
Heng, J. S., Rattner, A., Stein-O’Brien, G. L., Winer, B. L., Jones, B. W., Vernon, H. J., Goff, L. A. & Nathans, J., Apr 30 2019, In: Proceedings of the National Academy of Sciences of the United States of America. 116, 18, p. 9103-9114 12 p.Research output: Contribution to journal › Article › peer-review
Open Access17 Scopus citations -
Roles of HIFs and VEGF in angiogenesis in the retina and brain
Rattner, A., Williams, J. & Nathans, J., Sep 3 2019, In: Journal of Clinical Investigation. 129, 9, p. 3807-3820 14 p.Research output: Contribution to journal › Article › peer-review
Open Access26 Scopus citations -
2018
Affinity capture of polyribosomes followed by RNAseq (ACAPseq), a discovery platform for protein-protein interactions
Peng, X., Emiliani, F., Smallwood, P. M., Rattner, A., Lei, H., Sabbagh, M. F. & Nathans, J., Oct 2018, In: eLife. 7, e40982.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
Transcriptional and epigenomic landscapes of CNS and non-CNS vascular endothelial cells
Sabbagh, M. F., Heng, J. S., Luo, C., Castanon, R. G., Nery, J. R., Rattner, A., Goff, L. A., Ecker, J. R. & Nathans, J., Sep 2018, In: eLife. 7, e36187.Research output: Contribution to journal › Article › peer-review
Open Access70 Scopus citations -
2016
Frizzled Receptors in Development and Disease
Wang, Y., Chang, H., Rattner, A. & Nathans, J., Dec 1 2016, Current Topics in Developmental Biology. Academic Press Inc., p. 113-139 27 p. (Current Topics in Developmental Biology; vol. 117).Research output: Chapter in Book/Report/Conference proceeding › Chapter
Open Access59 Scopus citations -
Patterning of papillae on the mouse tongue: A system for the quantitative assessment of planar cell polarity signaling
Wang, Y., Williams, J., Rattner, A., Wu, S., Bassuk, A. G., Goffinet, A. M. & Nathans, J., Nov 15 2016, In: Developmental biology. 419, 2, p. 298-310 13 p.Research output: Contribution to journal › Article › peer-review
Open Access16 Scopus citations -
2014
Canonical WNT signaling components in vascular development and barrier formation
Zhou, Y., Wang, Y., Tischfield, M., Williams, J., Smallwood, P. M., Rattner, A., Taketo, M. M. & Nathans, J., Sep 2 2014, In: Journal of Clinical Investigation. 124, 9, p. 3825-3846 22 p.Research output: Contribution to journal › Article › peer-review
Open Access150 Scopus citations -
Cellular Resolution Maps of X Chromosome Inactivation: Implications for Neural Development, Function, and Disease
Wu, H., Luo, J., Yu, H., Rattner, A., Mo, A., Wang, Y., Smallwood, P. M., Erlanger, B., Wheelan, S. J. & Nathans, J., Jan 8 2014, In: Neuron. 81, 1, p. 103-119 17 p.Research output: Contribution to journal › Article › peer-review
Open Access121 Scopus citations -
The role of the hypoxia response in shaping retinal vascular development in the absence of norrin/frizzled4 signaling
Rattner, A., Wang, Y., Zhou, Y., Williams, J. & Nathans, J., 2014, In: Investigative Ophthalmology and Visual Science. 55, 12, p. 8614-8625 12 p.Research output: Contribution to journal › Article › peer-review
Open Access20 Scopus citations -
2013
Endothelin-2 deficiency causes growth retardation, hypothermia, and emphysema in mice
Chang, I., Bramall, A. N., Baynash, A. G., Rattner, A., Rakheja, D., Post, M., Joza, S., McKerlie, C., Stewart, D. J., McInnes, R. R. & Yanagisawa, M., Jun 3 2013, In: Journal of Clinical Investigation. 123, 6, p. 2643-2653 11 p.Research output: Contribution to journal › Article › peer-review
Open Access18 Scopus citations -
Endothelin-2 signaling in the neural retina promotes the endothelial tip cell state and inhibits angiogenesis
Rattner, A., Yu, H., Williams, J., Smallwood, P. M. & Nathans, J., Oct 1 2013, In: Proceedings of the National Academy of Sciences of the United States of America. 110, 40, p. E3830-E3839Research output: Contribution to journal › Article › peer-review
Open Access24 Scopus citations -
How to draw the line in biomedical research
Huang, L., Rattner, A., Liu, H. & Nathans, J., Mar 19 2013, In: eLife. 2013, 2, e00638.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
2012
Injury-independent induction of reactive gliosis in retina by loss of function of the LIM homeodomain transcription factor Lhx2
De Melo, J., Miki, K., Rattner, A., Smallwood, P., Zibetti, C., Hirokawa, K., Monuki, E. S., Campochiaro, P. A. & Blackshaw, S., Mar 20 2012, In: Proceedings of the National Academy of Sciences of the United States of America. 109, 12, p. 4657-4662 6 p.Research output: Contribution to journal › Article › peer-review
Open Access45 Scopus citations -
Norrin/Frizzled4 signaling in retinal vascular development and blood brain barrier plasticity
Wang, Y., Rattner, A., Zhou, Y., Williams, J., Smallwood, P. M. & Nathans, J., Dec 7 2012, In: Cell. 151, 6, p. 1332-1344 13 p.Research output: Contribution to journal › Article › peer-review
Open Access196 Scopus citations -
2011
Genetic mosaic analysis reveals a major role for frizzled 4 and frizzled 8 in controlling ureteric growth in the developing kidney
Ye, X., Wang, Y., Rattner, A. & Nathans, J., Mar 2011, In: Development. 138, 6, p. 1161-1172 12 p.Research output: Contribution to journal › Article › peer-review
43 Scopus citations -
Preclinical assessment of CNS drug action using eye movements in mice
Cahill, H., Rattner, A. & Nathans, J., Sep 1 2011, In: Journal of Clinical Investigation. 121, 9, p. 3528-3541 14 p.Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations -
2008
The genomic response of the retinal pigment epithelium to light damage and retinal detachment
Rattner, A., Toulabi, L., Williams, J., Yu, H. & Nathans, J., Sep 24 2008, In: Journal of Neuroscience. 28, 39, p. 9880-9889 10 p.Research output: Contribution to journal › Article › peer-review
Open Access33 Scopus citations -
2006
An evolutionary perspective on the photoreceptor damage response
Rattner, A. & Nathans, J., Mar 2006, In: American journal of ophthalmology. 141, 3, p. 558-562.e2Research output: Contribution to journal › Article › peer-review
11 Scopus citations -
Effects of L1 retrotransposon insertion on transcript processing, localization and accumulation: Lessons from the retinal degeneration 7 mouse and implications for the genomic ecology of L1 elements
Chen, J., Rattner, A. & Nathans, J., Jul 2006, In: Human molecular genetics. 15, 13, p. 2146-2156 11 p.Research output: Contribution to journal › Article › peer-review
51 Scopus citations -
Macular degeneration: Recent advances and therapeutic opportunities
Rattner, A. & Nathans, J., Nov 2006, In: Nature Reviews Neuroscience. 7, 11, p. 860-872 13 p.Research output: Contribution to journal › Review article › peer-review
169 Scopus citations -
2005
The genomic response to retinal disease and injury: Evidence for endothelin signaling from photoreceptors to glia
Rattner, A. & Nathans, J., May 4 2005, In: Journal of Neuroscience. 25, 18, p. 4540-4549 10 p.Research output: Contribution to journal › Article › peer-review
Open Access153 Scopus citations -
The rod photoreceptor-specific nuclear receptor Nr2e3 represses transcription of multiple cone-specific genes
Chen, J., Rattner, A. & Nathans, J., Jan 5 2005, In: Journal of Neuroscience. 25, 1, p. 118-129 12 p.Research output: Contribution to journal › Article › peer-review
Open Access200 Scopus citations -
2004
An Outer Segment Localization Signal at the C Terminus of the Photoreceptor-Specific Retinol Dehydrogenase
Luo, W., Marsh-Armstrong, N., Rattner, A. & Nathans, J., Mar 17 2004, In: Journal of Neuroscience. 24, 11, p. 2623-2632 10 p.Research output: Contribution to journal › Article › peer-review
Open Access44 Scopus citations -
Proteolytic shedding of the extracellular domain of photoreceptor cadherin: Implications for outer segment assembly
Rattner, A., Chen, J. & Nathans, J., Oct 1 2004, In: Journal of Biological Chemistry. 279, 40, p. 42202-42210 9 p.Research output: Contribution to journal › Article › peer-review
Open Access36 Scopus citations -
2001
A photoreceptor-specific cadherin is essential for the structural integrity of the outer segment and for photoreceptor survival
Rattner, A., Smallwood, P. M., Williams, J., Cooke, C., Savchenko, A., Lyubarsky, A., Pugh, E. N. & Nathans, J., Dec 6 2001, In: Neuron. 32, 5, p. 775-786 12 p.Research output: Contribution to journal › Article › peer-review
Open Access90 Scopus citations -
Insights into Wnt binding and signalling from the structures of two Frizzled cysteine-rich domains
Dann, C. E., Hsieh, J. C., Rattner, A., Sharma, D., Nathans, J. & Leahy, D. J., Jul 5 2001, In: Nature. 412, 6842, p. 86-90 5 p.Research output: Contribution to journal › Article › peer-review
343 Scopus citations -
2000
Identification and characterization of all-trans-retinol dehydrogenase from photoreceptor outer segments, the visual cycle enzyme that reduces all- trans-retinal to all-trans-retinol
Rattner, A., Smallwood, P. M. & Nathans, J., Apr 14 2000, In: Journal of Biological Chemistry. 275, 15, p. 11034-11043 10 p.Research output: Contribution to journal › Article › peer-review
Open Access162 Scopus citations -
1999
A new secreted protein that binds to Wnt proteins and inhibits their activites
Hsieh, J. C., Kodjabachian, L., Rebbert, M. L., Rattner, A., Smallwood, P. M., Samos, C. H., Nusse, R., Dawid, I. B. & Nathans, J., Apr 1 1999, In: Nature. 398, 6726, p. 431-436 6 p.Research output: Contribution to journal › Article › peer-review
549 Scopus citations -
Biochemical characterization of Wnt-frizzled interactions using a soluble, biologically active vertebrate Wnt protein
Hsieh, J. C., Rattner, A., Smallwood, P. M. & Nathans, J., Mar 30 1999, In: Proceedings of the National Academy of Sciences of the United States of America. 96, 7, p. 3546-3551 6 p.Research output: Contribution to journal › Article › peer-review
Open Access276 Scopus citations -
Cloning and characterization of a secreted frizzled-related protein that is expressed by the retinal pigment epithelium
Chang, J. T., Esumi, N., Moore, K., Li, Y., Zhang, S., Chew, C., Goodman, B., Rattner, A., Moody, S., Stetten, G., Campochiaro, P. A. & Zack, D. J., 1999, In: Human molecular genetics. 8, 4, p. 575-583 9 p.Research output: Contribution to journal › Article › peer-review
Open Access90 Scopus citations -
CPG16, a novel protein serine/threonine kinase downstream of cAMP- dependent protein kinase
Silverman, M. A., Benard, O., Jaaro, H., Rattner, A., Citri, Y. & Seger, R., Jan 29 1999, In: Journal of Biological Chemistry. 274, 5, p. 2631-2636 6 p.Research output: Contribution to journal › Article › peer-review
Open Access49 Scopus citations -
Molecular genetics of human retinal disease
Rattner, A., Sun, H. & Nathans, J., 1999, In: Annual review of genetics. 33, p. 89-131 43 p.Research output: Contribution to journal › Review article › peer-review
186 Scopus citations -
1998
Hippocampal plasticity involves extensive gene induction and multiple cellular mechanisms
Hevroni, D., Rattner, A., Bundman, M., Lederfein, D., Gabarah, A., Mangelus, M., Silverman, M. A., Kedar, H., Naor, C., Kornuc, M., Hanoch, T., Seger, R., Theill, L. E., Nedivi, E., Richter-Levin, G. & Citri, Y., 1998, In: Journal of Molecular Neuroscience. 10, 2, p. 75-98 24 p.Research output: Contribution to journal › Article › peer-review
136 Scopus citations -
1997
A family of secreted proteins contains homology to the cysteine-rich ligand-binding domain of frizzled receptors
Rattner, A., Hsieh, J. C., Smallwood, P. M., Gilbert, D. J., Copeland, N. G., Jenkins, N. A. & Nathans, J., Apr 1 1997, In: Proceedings of the National Academy of Sciences of the United States of America. 94, 7, p. 2859-2863 5 p.Research output: Contribution to journal › Article › peer-review
Open Access468 Scopus citations -
A photoreceptor cell-specific ATP-binding transporter gene (ABCR) is mutated in recessive Stargardt macular dystrophy
Allikmets, R., Singh, N., Sun, H., Shroyer, N. F., Hutchinson, A., Chidambaram, A., Gerrard, B., Baird, L., Stauffer, D., Peiffer, A., Rattner, A., Smallwood, P., Li, Y., Anderson, K. L., Lewis, R. A., Nathans, J., Leppert, M., Dean, M. & Lupski, J. R., Mar 1997, In: Nature genetics. 15, 3, p. 236-246 11 p.Research output: Contribution to journal › Article › peer-review
1006 Scopus citations -
1993
NF-κB activates the HIV promoter in neurons
Rattner, A., Korner, M., Walker, M. D. & Citri, Y., 1993, In: EMBO Journal. 12, 11, p. 4261-4267 7 p.Research output: Contribution to journal › Article › peer-review
Open Access77 Scopus citations -
1991
Nuclear Factor κB Activates Proenkephalin Transcription in T Lymphocytes
Rattner, A., Korner, M., Rosen, H., Baeuerle, P. A. & Citri, Y., Feb 1991, In: Molecular and cellular biology. 11, 2, p. 1017-1022 6 p.Research output: Contribution to journal › Article › peer-review
Open Access50 Scopus citations -
1989
A brain-specific transcription activator
Korner, M., Rattner, A., Mauxion, F., Sen, R. & Citri, Y., Nov 1989, In: Neuron. 3, 5, p. 563-572 10 p.Research output: Contribution to journal › Article › peer-review
102 Scopus citations