Ami Shah

Associate Professor

20062020

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Advances at the interface of cancer and systemic sclerosis

Mecoli, C. A., Rosen, A., Casciola-Rosen, L. & Shah, A. A., Jan 1 2020, (Accepted/In press) In : Journal of Scleroderma and Related Disorders.

Research output: Contribution to journalArticle

Open Access

ANCA-associated vasculitis in scleroderma: A renal perspective

Kant, S., Shah, A., Hummers, L., Wigley, F. & Geetha, D., Dec 1 2018, In : Clinical Nephrology. 90, 6, p. 413-418 6 p.

Research output: Contribution to journalArticle

Anti–RNPC-3 (U11/U12) Antibodies in Systemic Sclerosis in Patients With Moderate-to-Severe Gastrointestinal Dysmotility

McMahan, Z., Domsic, R. T., Zhu, L., Medsger, T. A., Casciola Rosen, L. A. & Shah, A., Sep 1 2019, In : Arthritis Care and Research. 71, 9, p. 1164-1170 7 p.

Research output: Contribution to journalArticle

Association of anti-RNA polymerase III autoantibodies and cancer in scleroderma

Moinzadeh, P., Fonseca, C., Hellmich, M., Shah, A. A., Chighizola, C., Denton, C. P. & Ong, V. H., Feb 14 2014, In : Arthritis Research and Therapy. 16, 1, R53.

Research output: Contribution to journalArticle

Association of Fibrosing Myopathy in Systemic Sclerosis and Higher Mortality

Paik, J., Wigley, F., Shah, A., Corse, A. M., Casciola Rosen, L. A., Hummers, L. & Mammen, A. L., Nov 1 2017, In : Arthritis Care and Research. 69, 11, p. 1764-1770 7 p.

Research output: Contribution to journalArticle

Open Access

Association of the autoimmune disease scleroderma with an immunologic response to cancer

Joseph, C. G., Darrah, E., Shah, A. A., Skora, A. D., Casciola-Rosen, L. A., Wigley, F. M., Boin, F., Fava, A., Thoburn, C., Kinde, I., Jiao, Y., Papadopoulos, N., Kinzler, K. W., Vogelstein, B. & Rosen, A., Jan 1 2014, In : Science. 343, 6167, p. 152-157 6 p.

Research output: Contribution to journalArticle

Barriers and Facilitators of Mentoring for Trainees and Early Career Investigators in Rheumatology Research: Current State, Identification of Needs, and Road Map to an Inter-Institutional Adult Rheumatology Mentoring Program

for the American College of Rheumatology Early Career Investigator Subcommittee of the Committee on Research, Mar 2018, In : Arthritis Care and Research. 70, 3, p. 445-453 9 p.

Research output: Contribution to journalArticle

Barriers to and facilitators of a career as a physician-scientist among rheumatologists in the US

Ogdie, A., Shah, A. A., Makris, U. E., Jiang, Y., Nelson, A. E., Kim, A. H. J., Angeles-Han, S. T., Castelino, F. V., Golding, A., Muscal, E., Kahlenberg, J. M. & Barg, F. K., Sep 1 2015, In : Arthritis Care and Research. 67, 9, p. 1191-1201 11 p.

Research output: Contribution to journalArticle

Brief Report: Anti–RNPC-3 Antibodies As a Marker of Cancer-Associated Scleroderma

Shah, A., Xu, G., Rosen, A., Hummers, L., Wigley, F., Elledge, S. J. & Casciola Rosen, L. A., Jun 1 2017, In : Arthritis and Rheumatology. 69, 6, p. 1306-1312 7 p.

Research output: Contribution to journalArticle

Brief Report: Whole-Exome Sequencing to Identify Rare Variants and Gene Networks That Increase Susceptibility to Scleroderma in African Americans

Gourh, P., Remmers, E. F., Boyden, S. E., Alexander, T., Morgan, N. D., Shah, A. A., Mayes, M. D., Doumatey, A., Bentley, A. R., Shriner, D., Domsic, R. T., Medsger, T. A., Steen, V. D., Ramos, P. S., Silver, R. M., Korman, B., Varga, J., Schiopu, E., Khanna, D., Hsu, V. & 22 others, Gordon, J. K., Saketkoo, L. A., Gladue, H., Kron, B., Criswell, L. A., Derk, C. T., Bridges, S. L., Shanmugam, V. K., Kolstad, K. D., Chung, L., Jan, R., Bernstein, E. J., Goldberg, A., Trojanowski, M., Kafaja, S., Maksimowicz-McKinnon, K. M., Mullikin, J. C., Adeyemo, A., Rotimi, C., Boin, F., Kastner, D. L. & Wigley, F. M., Oct 2018, In : Arthritis and Rheumatology. 70, 10, p. 1654-1660 7 p.

Research output: Contribution to journalArticle

Cancer and autoimmunity: Harnessing longitudinal cohorts to probe the link

Egiziano, G., Bernatsky, S. & Shah, A., 2016, (Accepted/In press) In : Best Practice and Research: Clinical Rheumatology.

Research output: Contribution to journalArticle

Cardiac metabolomics and autopsy in a patient with early diffuse systemic sclerosis presenting with dyspnea: A case report

Frech, T. M., Revelo, M. P., Ryan, J. J., Shah, A. A., Gordon, J., Domsic, R., Hant, F., Assassi, S., Shanmugam, V. K., Hinchcliff, M., Steen, V., Khanna, D., Bernstein, E. J., Cox, J., Luem, N. & Drakos, S., Jun 10 2015, In : Journal of Medical Case Reports. 9, 1, 136.

Research output: Contribution to journalArticle

Clinical and serological features of systemic sclerosis in a multicenter African American cohort: Analysis of the genome research in African American scleroderma patients clinical database

Morgan, N. D., Shah, A. A., Mayes, M. D., Domsic, R. T., Medsger, T. A., Steen, V. D., Varga, J., Carns, M., Ramos, P. S., Silver, R. M., Schiopu, E., Khanna, DI., Hsu, V., Gordon, J. K., Gladue, H., Saketkoo, L. A., Criswell, L. A., Derk, C. T., Trojanowski, M. A., Shanmugam, V. K. & 9 others, Chung, L., Valenzuela, A., Jan, R., Goldberg, A., Remmers, E. F., Kastner, D. L., Wigley, F. M., Gourh, P. & Boin, F., Dec 1 2017, In : Medicine (United States). 96, 51, e8980.

Research output: Contribution to journalArticle

Collaborative National Quality and Efficacy Registry (CONQUER) for Scleroderma: outcomes from a multicenter US-based systemic sclerosis registry

Shanmugam, V. K., Frech, T. M., Steen, V. D., Hummers, L. K., Shah, A. A., Bernstein, E. J., Khanna, D., Gordon, J. K., Castelino, F. V., Chung, L., Hant, F. N., Startup, E., VanBuren, J. M., Evnin, L. B. & Assassi, S., Jan 1 2019, (Accepted/In press) In : Clinical rheumatology.

Research output: Contribution to journalArticle

Connective tissue disease related interstitial lung diseases and idiopathic pulmonary fibrosis: Provisional core sets of domains and instruments for use in clinical trials

Saketkoo, L. A., Mittoo, S., Huscher, D., Khanna, D., Dellaripa, P. F., Distler, O., Flaherty, K. R., Frankel, S., Oddis, C. V., Denton, C. P., Fischer, A., Kowal-Bielecka, O. M., Lesage, D., Merkel, P. A., Phillips, K., Pittrow, D., Swigris, J., Antoniou, K., Baughman, R. P., Castelino, F. V. & 21 others, Christmann, R. B., Christopher-Stine, L., Collard, H. R., Cottin, V., Danoff, S., Highland, K. B., Hummers, L., Shah, A. A., Kim, D. S., Lynch, D. A., Miller, F. W., Proudman, S. M., Richeldi, L., Ryu, J. H., Sandorfi, N., Sarver, C., Wells, A. U., Strand, V., Matteson, E. L., Brown, K. K. & Seibold, J. R., May 2014, In : Thorax. 69, 5, p. 428-436 9 p.

Research output: Contribution to journalArticle

Consensus opinion of a North American Working Group regarding the classification of digital ulcers in systemic sclerosis

Baron, M., Chung, L., Gyger, G., Hummers, L., Khanna, D., Mayes, M. D., Pope, J. E., Shah, A. A., Steen, V. D., Steele, R., Tatibouet, S., Herrick, A., Müller-Ladner, U. & Hudson, M., Feb 1 2014, In : Clinical rheumatology. 33, 2, p. 207-214 8 p.

Research output: Contribution to journalArticle

Epigenetic activation and memory at a TGFB2 enhancer in systemic sclerosis

Shin, J. Y., Beckett, J. D., Bagirzadeh, R., Creamer, T. J., Shah, A. A., McMahan, Z., Paik, J. J., Sampedro, M. M., MacFarlane, E. G., Beer, M. A., Warren, D., Wigley, F. M. & Dietz, H. C., Jan 1 2019, In : Science translational medicine. 11, 497, eaaw0790.

Research output: Contribution to journalArticle

Estimating autoantibody signatures to detect autoimmune disease patient subsets

Wu, Z., Casciola-Rosen, L., Shah, A. A., Rosen, A. & Zeger, S. L., Jan 1 2019, In : Biostatistics. 20, 1, p. 30-47 18 p.

Research output: Contribution to journalArticle

Exhaled nitric oxide in pulmonary arterial hypertension associated with systemic sclerosis

Cao, Z., Mathai, S. C., Hummers, L. K., Shah, A. A., Wigley, F. M., Lechtzin, N., Hassoun, P. M. & Girgis, R. E., Dec 1 2016, In : Pulmonary Circulation. 6, 4, p. 545-550 6 p.

Research output: Contribution to journalArticle

Generation of a Core Set of Items to Develop Classification Criteria for Scleroderma Renal Crisis Using Consensus Methodology

the Scleroderma Clinical Trials Consortium Scleroderma Renal Crisis Working Group, Jun 2019, In : Arthritis and Rheumatology. 71, 6, p. 964-971 8 p.

Research output: Contribution to journalArticle

Genetic susceptibility loci of idiopathic interstitial pneumonia do not represent risk for systemic sclerosis: A case control study in Caucasian patients

Wu, M., Assassi, S., Salazar, G. A., Pedroza, C., Gorlova, O. Y., Chen, W. V., Charles, J., Taing, M. L., Liao, K., Wigley, F. M., Hummers, L. K., Shah, A. A., Hinchcliff, M., Khanna, D., Schiopu, E., Phillips, K., Furst, D. E., Steen, V., Baron, M., Hudson, M. & 17 others, Zhou, X., Pope, J., Jones, N., Docherty, P., Khalidi, N. A., Robinson, D., Simms, R. W., Silver, R. M., Frech, T. M., Fessler, B. J., Fritzler, M. J., Molitor, J. A., Segal, B. M., Movahedian, M., Martín, J., Varga, J. & Mayes, M. D., Jan 20 2016, In : Arthritis Research and Therapy. 18, 1, 20.

Research output: Contribution to journalArticle

Global skin gene expression analysis of early diffuse cutaneous systemic sclerosis shows a prominent innate and adaptive inflammatory profile

Skaug, B., Khanna, D., Swindell, W. R., Hinchcliff, M. E., Frech, T. M., Steen, V. D., Hant, F. N., Gordon, J. K., Shah, A. A., Zhu, L., Zheng, W. J., Browning, J. L., Barron, A. M. S., Wu, M., Visvanathan, S., Baum, P., Franks, J. M., Whitfield, M. L., Shanmugam, V. K., Domsic, R. T. & 8 others, Castelino, F. V., Bernstein, E. J., Wareing, N., Lyons, M. A., Ying, J., Charles, J., Mayes, M. D. & Assassi, S., Jan 1 2019, (Accepted/In press) In : Annals of the rheumatic diseases.

Research output: Contribution to journalArticle

HLA and autoantibodies define scleroderma subtypes and risk in African and European Americans and suggest a role for molecular mimicry

Gourh, P., Safran, S. A., Alexander, T., Boyden, S. E., Morgan, N. D., Shah, A. A., Mayes, M. D., Doumatey, A., Bentley, A. R., Shriner, D., Domsic, R. T., Medsger, T. A., Ramos, P. S., Silver, R. M., Steen, V. D., Varga, J., Hsu, V., Saketkoo, L. A., Schiopu, E., Khanna, D. & 24 others, Gordon, J. K., Kron, B., Criswell, L. A., Gladue, H., Derk, C. T., Bernstein, E. J., Bridges, S. L., Shanmugam, V. K., Kolstad, K. D., Chung, L., Kafaja, S., Jan, R., Trojanowski, M., Goldberg, A., Korman, B. D., Steinbach, P. J., Chandrasekharappa, S. C., Mullikin, J. C., Adeyemo, A., Rotimi, C., Wigley, F. M., Kastner, D. L., Boin, F. & Remmers, E. F., Jan 7 2020, In : Proceedings of the National Academy of Sciences of the United States of America. 117, 1, p. 552-562 11 p.

Research output: Contribution to journalArticle

Open Access

Impact of Radiation Therapy on Scleroderma and Cancer Outcomes in Scleroderma Patients With Breast Cancer

Shah, D. J., Hirpara, R., Poelman, C. L., Woods, A., Hummers, L., Wigley, F., Wright, J., Parekh, A., Steen, V. D., Domsic, R. T. & Shah, A., Oct 1 2018, In : Arthritis Care and Research. 70, 10, p. 1517-1524 8 p.

Research output: Contribution to journalArticle

Intravenous immunoglobulin may be an effective therapy for refractory, active diffuse cutaneous systemic sclerosis

Poelman, C. L., Hummers, L. K., Wigley, F. M., Anderson, C., Boin, F. & Shah, A. A., Feb 1 2015, In : Journal of Rheumatology. 42, 2, p. 236-242 7 p.

Research output: Contribution to journalArticle

IRF5 polymorphism predicts prognosis in patients with systemic sclerosis

Sharif, R., Mayes, M. D., Tan, F. K., Gorlova, O. Y., Hummers, L. K., Shah, A. A., Furst, D. E., Khanna, D., Martin, J., Bossini-Castillo, L., Gonzalez, E. B., Ying, J., Draeger, H. T., Agarwal, S. K., Reveille, J. D., Arnett, F. C., Wigley, F. M. & Assassi, S., Jul 1 2012, In : Annals of the rheumatic diseases. 71, 7, p. 1197-1202 6 p.

Research output: Contribution to journalArticle

Long-term experience of mycophenolate mofetil for treatment of diffuse cutaneous systemic sclerosis

Le, E. N., Wigley, F. M., Shah, A. A., Boin, F. & Hummers, L. K., Jun 1 2011, In : Annals of the rheumatic diseases. 70, 6, p. 1104-1107 4 p.

Research output: Contribution to journalArticle

Metastatic knee

Gelber, A. C. & Shah, A. A., Sep 1 2008, In : Journal of Rheumatology. 35, 9, 1 p.

Research output: Contribution to journalArticle

Molecular subsetting of interferon pathways in Sjögren's syndrome

Hall, J. C., Baer, A. N., Shah, A. A., Criswell, L. A., Shiboski, C. H., Rosen, A. & Casciola-Rosen, L., Sep 1 2015, In : Arthritis and Rheumatology. 67, 9, p. 2437-2446 10 p.

Research output: Contribution to journalArticle

My approach to the treatment of scleroderma

Shah, A. A. & Wigley, F. M., Apr 2013, In : Mayo Clinic proceedings. 88, 4, p. 377-393 17 p.

Research output: Contribution to journalArticle

Open label study of escalating doses of oral treprostinil diethanolamine in patients with systemic sclerosis and digital ischemia: Pharmacokinetics and correlation with digital perfusion

Shah, A. A., Schiopu, E., Hummers, L. K., Wade, M., Phillips, K., Anderson, C., Wise, R., Boin, F., Seibold, J. R., Wigley, F. & Rollins, K. D., Apr 18 2013, In : Arthritis Research and Therapy. 15, 1, R54.

Research output: Contribution to journalArticle

Outcome of pregnancies complicated by systemic sclerosis and mixed connective tissue disease

Chung, L., Flyckt, R. L. R., Colón, I., Shah, A. A., Druzin, M. & Chakravarty, E. F., Nov 7 2006, In : Lupus. 15, 9, p. 595-599 5 p.

Research output: Contribution to journalArticle

Patient perspectives in OMERACT provide an anchor for future metric development and improved approaches to healthcare delivery in connective tissue disease related interstitial lung disease (CTD-ILD)

Mittoo, S., Frankel, S., Lesage, D., Strand, V., Shah, A. A., Christopher-Stine, L., Danoff, S., Hummers, L. K., Swigris, J. J., Huscher, D., Christensen, A. M., Cenac, S. L., Erbil, J. K., Ferguson, S., Garcia-Valladares, I., Grewal, H. K., Orbai, A. M., Smith, K. C., Tran, M., Bingham, C. O. & 3 others, Castelino, F. V., Fischer, A. & Saketkoo, L. A., Sep 1 2015, In : Current Respiratory Medicine Reviews. 11, 2, p. 175-183 9 p.

Research output: Contribution to journalArticle