Ami Shah

Associate Professor

20062020
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Research Output 2006 2020

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Article
Article
Open Access
Immunotherapy
Referral and Consultation
Neoplasms
Odds Ratio
Educational Models

ANCA-associated vasculitis in scleroderma: A renal perspective

Kant, S., Shah, A., Hummers, L., Wigley, F. & Geetha, D., Dec 1 2018, In : Clinical Nephrology. 90, 6, p. 413-418 6 p.

Research output: Contribution to journalArticle

Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis
Kidney
Glomerulonephritis
Antineutrophil Cytoplasmic Antibodies
Immunosuppression
Gangrene
Interferons
Antibodies
Proteins
Case-Control Studies

Anti–RNPC-3 (U11/U12) Antibodies in Systemic Sclerosis in Patients With Moderate-to-Severe Gastrointestinal Dysmotility

McMahan, Z., Domsic, R. T., Zhu, L., Medsger, T. A., Casciola Rosen, L. A. & Shah, A., Sep 1 2019, In : Arthritis Care and Research. 71, 9, p. 1164-1170 7 p.

Research output: Contribution to journalArticle

Systemic Scleroderma
Antibodies
Interstitial Lung Diseases
Gastrointestinal Diseases
African Americans

Association of anti-RNA polymerase III autoantibodies and cancer in scleroderma

Moinzadeh, P., Fonseca, C., Hellmich, M., Shah, A., Chighizola, C., Denton, C. P. & Ong, V. H., Feb 14 2014, In : Arthritis Research and Therapy. 16, 1, R53.

Research output: Contribution to journalArticle

RNA Polymerase III
Autoantibodies
Neoplasms
Antibodies
Systemic Scleroderma

Association of Fibrosing Myopathy in Systemic Sclerosis and Higher Mortality

Paik, J., Wigley, F., Shah, A., Corse, A. M., Casciola Rosen, L. A., Hummers, L. & Mammen, A. L., Nov 1 2017, In : Arthritis Care and Research. 69, 11, p. 1764-1770 7 p.

Research output: Contribution to journalArticle

Systemic Scleroderma
Muscular Diseases
Muscles
Myositis
Mortality
Open Access
HLA-DRB1 Chains
Arthritis
Epitopes
Alleles
Immunogenetics

Association of the autoimmune disease scleroderma with an immunologic response to cancer

Joseph, C. G., Darrah, E., Shah, A., Skora, A. D., Casciola Rosen, L. A., Wigley, F., Boin, F., Fava, A., Thoburn, C., Kinde, I., Jiao, Y., Papadopoulos, N., Kinzler, K. W., Vogelstein, B. & Rosen, A., 2014, In : Science. 343, 6167, p. 152-157 6 p.

Research output: Contribution to journalArticle

Autoimmune Diseases
Neoplasms
Antibodies
Antigens
Connective Tissue Diseases
Autoantibodies
Phenotype
Neoplasms
Set theory
Incidence

Barriers and Facilitators of Mentoring for Trainees and Early Career Investigators in Rheumatology Research: Current State, Identification of Needs, and Road Map to an Inter-Institutional Adult Rheumatology Mentoring Program

Ogdie, A., Sparks, J. A., Angeles-Han, S. T., Bush, K., Castelino, F. V., Golding, A., Jiang, Y., Kahlenberg, J. M., Kim, A. H. J., Lee, Y. C., Machireddy, K., Ombrello, M. J., Shah, A., Wallace, Z. S., Nigrovic, P. A. & Makris, U. E., Jan 1 2018, (Accepted/In press) In : Arthritis Care and Research.

Research output: Contribution to journalArticle

Mentors
Rheumatology
Research Personnel
Research
Focus Groups

Barriers to and facilitators of a career as a physician-scientist among rheumatologists in the US

Ogdie, A., Shah, A., Makris, U. E., Jiang, Y., Nelson, A. E., Kim, A. H. J., Angeles-Han, S. T., Castelino, F. V., Golding, A., Muscal, E., Kahlenberg, J. M. & Barg, F. K., Sep 1 2015, In : Arthritis Care and Research. 67, 9, p. 1191-1201 11 p.

Research output: Contribution to journalArticle

Rheumatology
Physicians
Research
Research Personnel
Mentors

Brief Report: Whole-Exome Sequencing to Identify Rare Variants and Gene Networks That Increase Susceptibility to Scleroderma in African Americans

Gourh, P., Remmers, E. F., Boyden, S. E., Alexander, T., Morgan, N., Shah, A., Mayes, M. D., Doumatey, A., Bentley, A. R., Shriner, D., Domsic, R. T., Medsger, T. A., Steen, V. D., Ramos, P. S., Silver, R. M., Korman, B., Varga, J., Schiopu, E., Khanna, D., Hsu, V. & 22 others, Gordon, J. K., Saketkoo, L. A., Gladue, H., Kron, B., Criswell, L. A., Derk, C. T., Bridges, S. L., Shanmugam, V. K., Kolstad, K. D., Chung, L., Jan, R., Bernstein, E. J., Goldberg, A., Trojanowski, M., Kafaja, S., Maksimowicz-McKinnon, K. M., Mullikin, J. C., Adeyemo, A., Rotimi, C., Boin, F., Kastner, D. L. & Wigley, F., Oct 1 2018, In : Arthritis and Rheumatology. 70, 10, p. 1654-1660 7 p.

Research output: Contribution to journalArticle

Exome
Gene Regulatory Networks
African Americans
Systemic Scleroderma
Genes

Brief Report: Anti–RNPC-3 Antibodies As a Marker of Cancer-Associated Scleroderma

Shah, A., Xu, G., Rosen, A., Hummers, L., Wigley, F., Elledge, S. J. & Casciola Rosen, L. A., Jun 1 2017, In : Arthritis and Rheumatology. 69, 6, p. 1306-1312 7 p.

Research output: Contribution to journalArticle

Antibodies
Autoantibodies
Neoplasms
Cytidine Triphosphate
Odds Ratio

Cancer and autoimmunity: Harnessing longitudinal cohorts to probe the link

Egiziano, G., Bernatsky, S. & Shah, A., 2016, (Accepted/In press) In : Best Practice and Research: Clinical Rheumatology.

Research output: Contribution to journalArticle

Autoimmunity
Rheumatic Diseases
Neoplasms
Knowledge Bases
Rare Diseases
RNA Polymerase III
Neoplasms
Autoantibodies
Mutation
Early Detection of Cancer

Cancer and systemic sclerosis: Novel insights into pathogenesis and clinical implications

Shah, A. & Rosen, A., Nov 2011, In : Current Opinion in Rheumatology. 23, 6, p. 530-535 6 p.

Research output: Contribution to journalArticle

Systemic Scleroderma
Autoantigens
Neoplasms
RNA Polymerase III
Autoantibodies

Cardiac metabolomics and autopsy in a patient with early diffuse systemic sclerosis presenting with dyspnea: A case report

Frech, T. M., Revelo, M. P., Ryan, J. J., Shah, A., Gordon, J., Domsic, R., Hant, F., Assassi, S., Shanmugam, V. K., Hinchcliff, M., Steen, V., Khanna, D., Bernstein, E. J., Cox, J., Luem, N. & Drakos, S., Jun 10 2015, In : Journal of Medical Case Reports. 9, 1, 136.

Research output: Contribution to journalArticle

Diffuse Scleroderma
Metabolomics
Dyspnea
Autopsy
Respiratory Function Tests
Ventricular Pressure
Pulmonary Hypertension
Blood Pressure
Mortality
Hazards

Clinical and serological features of systemic sclerosis in a multicenter African American cohort: Analysis of the genome research in African American scleroderma patients clinical database

Morgan, N., Shah, A., Mayes, M. D., Domsic, R. T., Medsger, T. A., Steen, V. D., Varga, J., Carns, M., Ramos, P. S., Silver, R. M., Schiopu, E., Khanna, DI., Hsu, V., Gordon, J. K., Gladue, H., Saketkoo, L. A., Criswell, L. A., Derk, C. T., Trojanowski, M. A., Shanmugam, V. K. & 9 others, Chung, L., Valenzuela, A., Jan, R., Goldberg, A., Remmers, E. F., Kastner, D. L., Wigley, F., Gourh, P. & Boin, F., Dec 1 2017, In : Medicine (United States). 96, 51, e8980.

Research output: Contribution to journalArticle

Systemic Scleroderma
African Americans
Cohort Studies
Genome
Databases
Immunotherapy
Arthritis
Immunosuppression
Neoplasms
Phenotype
RNA Polymerase I
RNA Polymerase III
Antibodies
Autoantibodies
Neoplasms

Collaborative National Quality and Efficacy Registry (CONQUER) for Scleroderma: outcomes from a multicenter US-based systemic sclerosis registry

Shanmugam, V. K., Frech, T. M., Steen, V. D., Hummers, L. K., Shah, A. A., Bernstein, E. J., Khanna, D., Gordon, J. K., Castelino, F. V., Chung, L., Hant, F. N., Startup, E., VanBuren, J. M., Evnin, L. B. & Assassi, S., Jan 1 2019, (Accepted/In press) In : Clinical rheumatology.

Research output: Contribution to journalArticle

Systemic Scleroderma
Registries
Longitudinal Studies
Specimen Handling
Respiratory Function Tests

Connective tissue disease related interstitial lung diseases and idiopathic pulmonary fibrosis: Provisional core sets of domains and instruments for use in clinical trials

Saketkoo, L. A., Mittoo, S., Huscher, D., Khanna, D., Dellaripa, P. F., Distler, O., Flaherty, K. R., Frankel, S., Oddis, C. V., Denton, C. P., Fischer, A., Kowal-Bielecka, O. M., Lesage, D., Merkel, P. A., Phillips, K., Pittrow, D., Swigris, J., Antoniou, K., Baughman, R. P., Castelino, F. V. & 21 others, Christmann, R. B., Christopher-Stine, L., Collard, H. R., Cottin, V., Danoff, S., Highland, K. B., Hummers, L., Shah, A., Kim, D. S., Lynch, D. A., Miller, F. W., Proudman, S. M., Richeldi, L., Ryu, J. H., Sandorfi, N., Sarver, C., Wells, A. U., Strand, V., Matteson, E. L., Brown, K. K. & Seibold, J. R., 2014, In : Thorax. 69, 5, p. 428-436 9 p.

Research output: Contribution to journalArticle

Idiopathic Pulmonary Fibrosis
Connective Tissue Diseases
Interstitial Lung Diseases
Clinical Trials
Outcome Assessment (Health Care)

Consensus opinion of a North American Working Group regarding the classification of digital ulcers in systemic sclerosis

Baron, M., Chung, L., Gyger, G., Hummers, L., Khanna, D., Mayes, M. D., Pope, J. E., Shah, A., Steen, V. D., Steele, R., Tatibouet, S., Herrick, A., Müller-Ladner, U. & Hudson, M., Feb 2014, In : Clinical Rheumatology. 33, 2, p. 207-214 8 p.

Research output: Contribution to journalArticle

Systemic Scleroderma
Ulcer
Linear Models
Hand

Epigenetic activation and memory at a TGFB2 enhancer in systemic sclerosis

Shin, J. Y., Beckett, J. D., Bagirzadeh, R., Creamer, T. J., Shah, A. A., McMahan, Z., Paik, J. J., Sampedro, M. M., MacFarlane, E. G., Beer, M. A., Warren, D., Wigley, F. M. & Dietz, H. C., Jan 1 2019, In : Science translational medicine. 11, 497, eaaw0790.

Research output: Contribution to journalArticle

Systemic Scleroderma
Epigenomics
Fibrosis
Skin
Autocrine Communication

Estimating autoantibody signatures to detect autoimmune disease patient subsets

Wu, Z., Casciola Rosen, L. A., Shah, A., Rosen, A. & Zeger, S., Jan 1 2019, In : Biostatistics (Oxford, England). 20, 1, p. 30-47 18 p.

Research output: Contribution to journalArticle

Autoantibodies
Signature
Subset
Warping
Immune Response
Myositis
Rheumatic Diseases
Autoantibodies
Dermatomyositis
Breast Neoplasms
Autoantibodies
RNA Polymerase III
Neoplasms
Age of Onset
Type I DNA Topoisomerase

Exhaled nitric oxide in pulmonary arterial hypertension associated with systemic sclerosis

Cao, Z., Mathai, S., Hummers, L., Shah, A., Wigley, F., Lechtzin, N., Hassoun, P. M. & Girgis, R. E., Dec 1 2016, In : Pulmonary Circulation. 6, 4, p. 545-550 6 p.

Research output: Contribution to journalArticle

Systemic Scleroderma
Pulmonary Hypertension
Nitric Oxide
Healthy Volunteers
Lung

Generation of a Core Set of Items to Develop Classification Criteria for Scleroderma Renal Crisis Using Consensus Methodology

the Scleroderma Clinical Trials Consortium Scleroderma Renal Crisis Working Group, Jun 1 2019, In : Arthritis and Rheumatology. 71, 6, p. 964-971 8 p.

Research output: Contribution to journalArticle

Kidney
Hemolytic Anemia
Hemolysis
Proteinuria
Acute Kidney Injury

Genetic susceptibility loci of idiopathic interstitial pneumonia do not represent risk for systemic sclerosis: A case control study in Caucasian patients

Wu, M., Assassi, S., Salazar, G. A., Pedroza, C., Gorlova, O. Y., Chen, W. V., Charles, J., Taing, M. L., Liao, K., Wigley, F., Hummers, L., Shah, A., Hinchcliff, M., Khanna, D., Schiopu, E., Phillips, K., Furst, D. E., Steen, V., Baron, M., Hudson, M. & 17 others, Zhou, X., Pope, J., Jones, N., Docherty, P., Khalidi, N. A., Robinson, D., Simms, R. W., Silver, R. M., Frech, T. M., Fessler, B. J., Fritzler, M. J., Molitor, J. A., Segal, B. M., Movahedian, M., Martín, J., Varga, J. & Mayes, M. D., Jan 20 2016, In : Arthritis Research and Therapy. 18, 1, 20.

Research output: Contribution to journalArticle

Idiopathic Interstitial Pneumonias
Genetic Loci
Systemic Scleroderma
Genetic Predisposition to Disease
Case-Control Studies

Immune checkpoint inhibitor-induced inflammatory arthritis persists after immunotherapy cessation

Braaten, T. J., Brahmer, J., Forde, P., Le, D., Lipson, E., Naidoo, J., Schollenberger, M., Zheng, L., Bingham, C., Shah, A. & Cappelli, L., Jan 1 2019, (Accepted/In press) In : Annals of the rheumatic diseases.

Research output: Contribution to journalArticle

Immunotherapy
Arthritis
Tumors
Immunosuppressive Agents
Logistics

Impact of Radiation Therapy on Scleroderma and Cancer Outcomes in Scleroderma Patients With Breast Cancer

Shah, D. J., Hirpara, R., Poelman, C. L., Woods, A., Hummers, L., Wigley, F., Wright, J., Parekh, A., Steen, V. D., Domsic, R. T. & Shah, A., Oct 1 2018, In : Arthritis Care and Research. 70, 10, p. 1517-1524 8 p.

Research output: Contribution to journalArticle

Radiotherapy
Breast Neoplasms
Neoplasms
Systemic Scleroderma
Erythema
Sjogren's Syndrome
Arthritis
T-cells
Cells
Programmed Cell Death 1 Receptor

Intravenous immunoglobulin may be an effective therapy for refractory, active diffuse cutaneous systemic sclerosis

Poelman, C. L., Hummers, L., Wigley, F., Anderson, C., Boin, F. & Shah, A., Feb 1 2015, In : Journal of Rheumatology. 42, 2, p. 236-242 7 p.

Research output: Contribution to journalArticle

Diffuse Scleroderma
Intravenous Immunoglobulins
Mycophenolic Acid
Relaxin
Skin

IRF5 polymorphism predicts prognosis in patients with systemic sclerosis

Sharif, R., Mayes, M. D., Tan, F. K., Gorlova, O. Y., Hummers, L., Shah, A., Furst, D. E., Khanna, D., Martin, J., Bossini-Castillo, L., Gonzalez, E. B., Ying, J., Draeger, H. T., Agarwal, S. K., Reveille, J. D., Arnett, F. C., Wigley, F. & Assassi, S., Jul 2012, In : Annals of the Rheumatic Diseases. 71, 7, p. 1197-1202 6 p.

Research output: Contribution to journalArticle

Systemic Scleroderma
Polymorphism
Pulmonary diseases
Genes
Single Nucleotide Polymorphism

Laughter-induced Syncope

Shah, A. & Gelber, A., Jul 2010, In : American Journal of Medicine. 123, 7, p. 609-611 3 p.

Research output: Contribution to journalArticle

Vascular Surgical Procedures
Amaurosis Fugax
Laughter
Takayasu Arteritis
Syncope

Long-term experience of mycophenolate mofetil for treatment of diffuse cutaneous systemic sclerosis

Le, E. N., Wigley, F., Shah, A., Boin, F. & Hummers, L., Jun 2011, In : Annals of the Rheumatic Diseases. 70, 6, p. 1104-1107 4 p.

Research output: Contribution to journalArticle

Mycophenolic Acid
Diffuse Scleroderma
Skin
Relaxin
Penicillamine

Metastatic knee

Gelber, A. & Shah, A., Sep 2008, In : Journal of Rheumatology. 35, 9, p. 1894 1 p.

Research output: Contribution to journalArticle

Bone Neoplasms
Knee Joint
Knee
Breast Neoplasms
Neoplasm Metastasis

Molecular subsetting of interferon pathways in Sjögren's syndrome

Hall, J. C., Baer, A., Shah, A., Criswell, L. A., Shiboski, C. H., Rosen, A. & Casciola Rosen, L. A., Sep 1 2015, In : Arthritis and Rheumatology. 67, 9, p. 2437-2446 10 p.

Research output: Contribution to journalArticle

Interferons
Salivary Glands
Lip
Interferon-gamma
Lacrimal Apparatus
Localized Scleroderma
Systemic Scleroderma
Skin Neoplasms
Melanoma

My approach to the treatment of scleroderma

Shah, A. & Wigley, F., 2013, In : Mayo Clinic Proceedings. 88, 4, p. 377-393 17 p.

Research output: Contribution to journalArticle

Systemic Scleroderma
Therapeutics
Quality of Life
Musculoskeletal Pain
Expert Testimony

Often Forgotten Manifestations of Systemic Sclerosis

Shah, A. & Wigley, F., Feb 2008, In : Rheumatic Disease Clinics of North America. 34, 1, p. 221-238 18 p.

Research output: Contribution to journalArticle

Systemic Scleroderma
Oral Manifestations
Fecal Incontinence
Osteolysis
Thyroid Diseases

Open label study of escalating doses of oral treprostinil diethanolamine in patients with systemic sclerosis and digital ischemia: Pharmacokinetics and correlation with digital perfusion

Shah, A., Schiopu, E., Hummers, L., Wade, M., Phillips, K., Anderson, C., Wise, R. A., Boin, F., Seibold, J. R., Wigley, F. & Rollins, K. D., Apr 18 2013, (Accepted/In press) In : Arthritis Research and Therapy.

Research output: Contribution to journalArticle

diethanolamine
Systemic Scleroderma
Ischemia
Pharmacokinetics
Perfusion

Outcome of pregnancies complicated by systemic sclerosis and mixed connective tissue disease

Chung, L., Flyckt, R. L. R., Colón, I., Shah, A., Druzin, M. & Chakravarty, E. F., 2006, In : Lupus. 15, 9, p. 595-599 5 p.

Research output: Contribution to journalArticle

Mixed Connective Tissue Disease
Systemic Scleroderma
Pregnancy Outcome
Pregnancy
Small for Gestational Age Infant

Patient perspectives in OMERACT provide an anchor for future metric development and improved approaches to healthcare delivery in connective tissue disease related interstitial lung disease (CTD-ILD)

Mittoo, S., Frankel, S., Lesage, D., Strand, V., Shah, A., Christopher-Stine, L., Danoff, S., Hummers, L., Swigris, J. J., Huscher, D., Christensen, A. M., Cenac, S. L., Erbil, J. K., Ferguson, S., Garcia-Valladares, I., Grewal, H. K., Orbai, A-M., Smith, K., Tran, M., Bingham, C. & 3 others, Castelino, F. V., Fischer, A. & Saketkoo, L. A., Sep 1 2015, In : Current Respiratory Medicine Reviews. 11, 2, p. 175-183 9 p.

Research output: Contribution to journalArticle

Connective Tissue Diseases
Interstitial Lung Diseases
Delivery of Health Care
Focus Groups
Dyspnea
Raynaud Disease
Antibodies
Body Temperature Regulation
Autoantibodies
Serum
RNA Polymerase I
RNA Polymerase III
Antibodies
Neoplasms
Anti-Idiotypic Antibodies
African Americans
Mortality
Confidence Intervals
Odds Ratio
Systemic Scleroderma