Ameya Gokhale

Research Associate

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Peptidomimetics Medicine & Life Sciences
Experimental Arthritis Medicine & Life Sciences
Peptides Medicine & Life Sciences
Cell Adhesion Medicine & Life Sciences
Cell adhesion Chemical Compounds
Regulatory T-Lymphocytes Medicine & Life Sciences
Arthritis Medicine & Life Sciences
Proteins Medicine & Life Sciences

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Research Output 2010 2019

Selective deletion of Eos (Ikzf4) in T-regulatory cells leads to loss of suppressive function and development of systemic autoimmunity

Gokhale, A., Gangaplara, A., Lopez-Occasio, M., Thornton, A. M. & Shevach, E. M., Jan 1 2019, In : Journal of Autoimmunity.

Research output: Contribution to journalArticle

Regulatory T-Lymphocytes
Ikaros Transcription Factor
Myelin-Oligodendrocyte Glycoprotein

Type I interferon signaling attenuates regulatory T cell function in viral infection and in the tumor microenvironment

Gangaplara, A., Martens, C., Dahlstrom, E., Metidji, A., Gokhale, A., Glass, D. D., Lopez-Ocasio, M., Baur, R., Kanakabandi, K., Porcella, S. F. & Shevach, E. M., Apr 1 2018, In : PLoS pathogens. 14, 4, e1006985.

Research output: Contribution to journalArticle

Open Access
Interferon Type I
Tumor Microenvironment
Virus Diseases
Regulatory T-Lymphocytes
Lymphocytic choriomeningitis virus

CD74/DQA1 dimers predispose to the development of arthritis in humanized mice

David, L., Gokhale, A., Jois, S., Johnson, A., Behrens, M., Luthra, H. & Taneja, V., Feb 1 2016, In : Immunology. 147, 2, p. 204-211 8 p.

Research output: Contribution to journalArticle

Rheumatoid Arthritis
Collagen Type II

Inhibition of cell adhesion and immune responses in the mouse model of collagen-induced arthritis with a peptidomimetic that blocks CD2-CD58 interface interactions

Gokhale, A., Sable, R., Walker, J. D., McLaughlin, L., Kousoulas, K. G. & Jois, S. D., Nov 1 2015, In : Biopolymers. 104, 6, p. 733-742 10 p.

Research output: Contribution to journalArticle

Experimental Arthritis
Cell adhesion
Cell Adhesion

Novel peptidomimetics for inhibition of HER2:HER3 heterodimerization in HER2-positive breast cancer

Kanthala, S., Banappagari, S., Gokhale, A., Liu, Y. Y., Xin, G., Zhao, Y. & Jois, S., Jun 1 2015, In : Chemical Biology and Drug Design. 85, 6, p. 702-714 13 p.

Research output: Contribution to journalArticle

Breast Neoplasms