Alison Klein

Professor

19992019
If you made any changes in Pure, your changes will be visible here soon.

Research Output 1999 2019

Filter
Article
2014

Association of PD-1, PD-1 ligands, and other features of the tumor immune microenvironment with response to anti-PD-1 therapy

Taube, J. M., Klein, A., Brahmer, J., Xu, H., Pan, X., Kim, J. H., Chen, L., Pardoll, A. M., Topalian, S. & Anders, R. A., Oct 1 2014, In : Clinical Cancer Research. 20, 19, p. 5064-5074 11 p.

Research output: Contribution to journalArticle

Tumor Microenvironment
Ligands
Neoplasms
Renal Cell Carcinoma
Programmed Cell Death 1 Ligand 2 Protein

Familial and sporadic pancreatic cancer share the same molecular pathogenesis

Norris, A. L., Roberts, N., Jones, S., Wheelan, S., Papadopoulos, N., Vogelstein, B., Kinzler, K. W., Hruban, R. H., Klein, A. & Eshleman, J., Sep 21 2014, In : Familial Cancer. 14, 1, p. 95-103 9 p.

Research output: Contribution to journalArticle

Pancreatic Neoplasms
Adenocarcinoma
Age of Onset
Genes
RNA Sequence Analysis

Genome-wide association study identifies multiple susceptibility loci for pancreatic cancer

Wolpin, B. M., Rizzato, C., Kraft, P., Kooperberg, C., Petersen, G. M., Wang, Z., Arslan, A. A., Beane-Freeman, L., Bracci, P. M., Buring, J., Canzian, F., Duell, E. J., Gallinger, S., Giles, G. G., Goodman, G. E., Goodman, P. J., Jacobs, E. J., Kamineni, A., Klein, A., Kolonel, L. N. & 97 others, Kulke, M. H., Li, D., Malats, N., Olson, S. H., Risch, H. A., Sesso, H. D., Visvanathan, K., White, E., Zheng, W., Abnet, C. C., Albanes, D., Andreotti, G., Austin, M. A., Barfield, R., Basso, D., Berndt, S. I., Boutron-Ruault, M. C., Brotzman, M., Büchler, M. W., Bueno-De-Mesquita, H. B., Bugert, P., Burdette, L., Campa, D., Caporaso, N. E., Capurso, G., Chung, C., Cotterchio, M., Costello, E., Elena, J., Funel, N., Gaziano, J. M., Giese, N. A., Giovannucci, E. L., Goggins, M. S., Gorman, M. J., Gross, M., Haiman, C. A., Hassan, M., Helzlsouer, K. J., Henderson, B. E., Holly, E. A., Hu, N., Hunter, D. J., Innocenti, F., Jenab, M., Kaaks, R., Key, T. J., Khaw, K. T., Klein, E. A., Kogevinas, M., Krogh, V., Kupcinskas, J., Kurtz, R. C., Lacroix, A., Landi, M. T., Landi, S., Le Marchand, L., Mambrini, A., Mannisto, S., Milne, R. L., Nakamura, Y., Oberg, A. L., Owzar, K., Patel, A. V., Peeters, P. H. M., Peters, U., Pezzilli, R., Piepoli, A., Porta, M., Real, F. X., Riboli, E., Rothman, N., Scarpa, A., Shu, X. O., Silverman, D. T., Soucek, P., Sund, M., Talar-Wojnarowska, R., Taylor, P. R., Theodoropoulos, G. E., Thornquist, M., Tjønneland, A., Tobias, G. S., Trichopoulos, D., Vodicka, P., Wactawski-Wende, J., Wentzensen, N., Wu, C., Yu, H., Yu, K., Zeleniuch-Jacquotte, A., Hoover, R., Hartge, P., Fuchs, C., Chanock, S. J., Stolzenberg-Solomon, R. S. & Amundadottir, L. T., 2014, In : Nature Genetics. 46, 9, p. 994-1000 7 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Pancreatic Neoplasms
Odds Ratio
Confidence Intervals
Alleles

Germline rearrangements in families with strong family history of glioma and malignant melanoma colon, and breast cancer

Andersson, U., Wibom, C., Cederquist, K., Aradottir, S., Borg, Å., Armstrong, G. N., Shete, S., Lau, C. C., Bainbridge, M. N., Claus, E. B., Barnholtz-Sloan, J., Lai, R., Il'yasova, D., Houlston, R. S., Schildkraut, J., Bernstein, J. L., Olson, S. H., Jenkins, R. B., Lachance, D. H., Wrensch, M. & 158 others, Davis, F. G., Merrell, R., Johansen, C., Sadetzki, S., Bondy, M. L., Melin, B. S., Adatto, P., Morice, F., Payen, S., McQuinn, L., McGaha, R., Guerra, S., Paith, L., Roth, K., Zeng, D., Zhang, H., Yung, A., Aldape, K., Gilbert, M., Weinberger, J., Colman, H., Conrad, C., de Groot, J., Forman, A., Groves, M., Levin, V., Loghin, M., Puduvalli, V., Sawaya, R., Heimberger, A., Lang, F., Levine, N., Tolentino, L., Saunders, K., Thach, T. T., Iacono, D. D., Sloan, A., Gerson, S., Selman, W., Bambakidis, N., Hart, D., Miller, J., Hoffer, A., Cohen, M., Rogers, L., Nock, C. J., Wolinsky, Y., Devine, K., Fulop, J., Barrett, W., Shimmel, K., Ostrom, Q., Barnett, G., Rosenfeld, S., Vogelbaum, M., Weil, R., Ahluwalia, M., Peereboom, D., Staugaitis, S., Schilero, C., Brewer, C., Smolenski, K., McGraw, M., Naska, T., Ram, Z., Blumenthal, D. T., Bokstein, F., Umansky, F., Zaaroor, M., Cohen, A., Tzuk-Shina, T., Voldby, B., Laursen, R., Andersen, C., Brennum, J., Henriksen, M. B., Marzouk, M., Davis, M. E., Boland, E., Smith, M., Eze, O., Way, M., Lada, P., Miedzianowski, N., Frechette, M., Paleologos, N., Byström, G., Svedberg, E., Huggert, S., Kimdal, M., Sandström, M., Brännström, N., Hayat, A., Tihan, T., Zheng, S., Berger, M., Butowski, N., Chang, S., Clarke, J., Prados, M., Rice, T., Sison, J., Kivett, V., Duo, X., Hansen, H., Hsuang, G., Lamela, R., Ramos, C., Patoka, J., Wagenman, K., Zhou, M., Klein, A., McGee, N., Pfefferle, J., Wilson, C., Morris, P., Hughes, M., Britt-Williams, M., Foft, J., Madsen, J., Polony, C., McCarthy, B., Zahora, C., Villano, J., Engelhard, H., Chanock, S. K., Collins, P., Elston, R., Kleihues, P., Kruchko, C., Petersen, G., Plon, S., Thompson, P., Scheurer, M. E., Liu, Y., Yu, R. K., Aldape, K. D., Gilbert, M. R., Weinberg, J., Hosking, F. J., Robertson, L., Papaemmanuil, E., Sloan, A. E., McKean-Cowdin, R., Yechezkel, G. H., Bruchim, R. B., Aslanov, L., Kosteljanetz, M., Broholm, H., Schubert, E., DeAngelis, L., Yang, P., Rynearson, A., Henriksson, R., Wiencke, J., Wiemels, J., McCoy, L. & McCarthy, B. J., Jan 1 2014, In : Neuro-oncology. 16, 10, p. 1333-1340 8 p.

Research output: Contribution to journalArticle

Open Access
Glioma
Colonic Neoplasms
Melanoma
Breast Neoplasms
Neoplasms

Having pancreatic cancer with tumoral loss of ATM and normal TP53 protein expression is associated with a poorer prognosis

Kim, H., Saka, B., Knight, S., Borges, M., Childs, E., Klein, A., Wolfgang, C., Herman, J., Adsay, V. N., Hruban, R. H. & Goggins, M. S., Apr 1 2014, In : Clinical Cancer Research. 20, 7, p. 1865-1872 8 p.

Research output: Contribution to journalArticle

Tumor Suppressor Protein p53
Ataxia Telangiectasia
Pancreatic Neoplasms
Survival
Ataxia Telangiectasia Mutated Proteins

Imputation and subset-based association analysis across different cancer types identifies multiple independent risk loci in the TERT-CLPTM1L region on chromosome 5p15.33

Wang, Z., Zhu, B., Zhang, M., Parikh, H., Jia, J., Chung, C. C., Sampson, J. N., Hoskins, J. W., Hutchinson, A., Burdette, L., Ibrahim, A., Hautman, C., Raj, P. S., Abnet, C. C., Adjei, A. A., Ahlbom, A., Albanes, D., Allen, N. E., Ambrosone, C. B., Aldrich, M. & 331 others, Amiano, P., Amos, C., Andersson, U., Gerald Andriole, G. A., Andrulis, I. L., Arici, C., Arslan, A. A., Austin, M. A., Baris, D., Barkauskas, D. A., Bassig, B. A., Freeman, L. E. B., Berg, C. D., Berndt, S. I., Bertazzi, P. A., Biritwum, R. B., Black, A., Blot, W., Boeing, H., Boffetta, P., Bolton, K., Boutron-Ruault, M. C., Bracci, P. M., Brennan, P., Brinton, L. A., Brotzman, M., Bueno-de-Mesquita, H. B., Buring, J. E., Butler, M. A., Cai, Q., Cancel-Tassin, G., Canzian, F., Cao, G., Caporaso, N. E., Carrato, A., Carreon, T., Carta, A., Chang, G. C., Chang, I. S., Chang-Claude, J., Che, X., Chen, C. J., Chen, C. Y., Chen, C. H., Chen, C., Chen, K. Y., Chen, Y. M., Chokkalingam, A. P., Chu, L. W., Clavel-Chapelon, F., Colditz, G. A., Colt, J. S., Conti, D., Cook, M. B., Cortessis, V. K., Crawford, E. D., Cussenot, O., Davis, F. G., De Vivo, I., Deng, X., Ding, T., Dinney, C. P., Di Stefano, A. L., Diver, W. R., Duell, E. J., Elena, J. W., Fan, J. H., Feigelson, H. S., Feychting, M., Figueroa, J. D., Flanagan, A. M., Fraumeni, J. F., Freedman, N. D., Fridley, B. L., Fuchs, C. S., Gago-Dominguez, M., Gallinger, S., Gao, Y. T., Gapstur, S. M., Garcia-Closas, M., Garcia-Closas, R., Gastier-Foster, J. M., Gaziano, J. M., Gerhard, D. S., Giffen, C. A., Giles, G. G., Gillanders, E. M., Giovannucci, E. L., Goggins, M. S., Gokgoz, N., Goldstein, A. M., Gonzalez, C., Gorlick, R., Greene, M. H., Gross, M., Grossman, H. B., Grubb, R., Gu, J., Guan, P., Haiman, C. A., Hallmans, G., Hankinson, S. E., Harris, C. C., Hartge, P., Hattinger, C., Hayes, R. B., He, Q., Helman, L. J., Henderson, B. E., Henriksson, R., Hoffman-Bolton, J., Hohensee, C., Holly, E. A., Hong, Y. C., Hoover, R. N., Dean Hosgood, H., Hsiao, C. F., Hsing, A. W., Hsiung, C. A., Hu, N., Hu, W., Hu, Z., Huang, M. S., Hunter, D. J., Inskip, P. D., Ito, H., Jacobs, E. J., Jacobs, K. B., Jenab, M., Ji, B. T., Johansen, C., Johansson, M., Johnson, A., Kaaks, R., Kamat, A. M., Kamineni, A., Karagas, M., Khanna, C., Khaw, K. T., Kim, C., Kim, I. S., Kim, J. H., Kim, Y. H., Kim, Y. C., Kim, Y. T., Kang, C. H., Jung, Y. J., Kitahara, C. M., Klein, A., Klein, R., Kogevinas, M., Koh, W. P., Kohno, T., Kolonel, L. N., Kooperberg, C., Kratz, C. P., Krogh, V., Kunitoh, H., Kurtz, R. C., Kurucu, N., Lan, Q., Lathrop, M., Lau, C. C., Lecanda, F., Lee, K. M., Lee, M. P., Marchand, L. L., Lerner, S. P., Li, D., Liao, L. M., Lim, W. Y., Lin, D., Lin, J., Lindstrom, S., Linet, M. S., Lissowska, J., Liu, J., Ljungberg, B., Lloreta, J., Lu, D., Ma, J., Malats, N., Mannisto, S., Marina, N., Mastrangelo, G., Matsuo, K., McGlynn, K. A., McKean-Cowdin, R., McNeil, L. H., McWilliams, R. R., Melin, B. S., Meltzer, P. S., Mensah, J. E., Miao, X., Michaud, D. S., Mondul, A. M., Moore, L. E., Muir, K., Niwa, S., Olson, S. H., Orr, N., Panico, S., Park, J. Y., Patel, A. V., Patino-Garcia, A., Pavanello, S., Peeters, P. H. M., Peplonska, B., Peters, U., Petersen, G. M., Picci, P., Pike, M. C., Porru, S., Prescott, J., Pu, X., Purdue, M. P., Qiao, Y. L., Rajaraman, P., Riboli, E., Risch, H. A., Rodabough, R. J., Rothman, N., Ruder, A. M., Ryu, J. S., Sanson, M., Schned, A., Schumacher, F. R., Schwartz, A. G., Schwartz, K. L., Schwenn, M., Scotlandi, K., Seow, A., Serra, C., Serra, M., Sesso, H. D., Severi, G., Shen, H., Shen, M., Shete, S., Shiraishi, K., Shu, X. O., Siddiq, A., Sierrasesumaga, L., Sierri, S., Sihoe, A. D. L., Silverman, D. T., Simon, M., Southey, M. C., Spector, L., Spitz, M., Stampfer, M., Stattin, P., Stern, M. C., Stevens, V. L., Stolzenberg-Solomon, R. Z., Stram, D. O., Strom, S. S., Su, W. C., Sund, M., Sung, S. W., Swerdlow, A., Tan, W., Tanaka, H., Tang, W., Tang, Z. Z., Tardon, A., Tay, E., Taylor, P. R., Tettey, Y., Thomas, D. M., Tirabosco, R., Tjonneland, A., Tobias, G. S., Toro, J. R., Travis, R. C., Trichopoulos, D., Troisi, R., Truelove, A., Tsai, Y. H., Tucker, M. A., Tumino, R., Van Den Berg, D., Van Den Eeden, S. K., Vermeulen, R., Vineis, P., Visvanathan, K., Vogel, U., Wang, C., Wang, C., Wang, J., Wang, S. S., Weiderpass, E., Weinstein, S. J., Wentzensen, N., Wheeler, W., White, E., Wiencke, J. K., Wolk, A., Wolpin, B. M., Wong, M. P., Wrensch, M., Wu, C., Wu, T., Wu, X., Wu, Y. L., Wunder, J. S., Xiang, Y. B., Xu, J., Yang, H. P., Yang, P. C., Yatabe, Y., Ye, Y., Yeboah, E. D., Yin, Z., Ying, C., Yu, C. J., Yu, K., Yuan, J. M., Zanetti, K. A., Zeleniuch-Jacquotte, A., Zheng, W., Zhou, B., Mirabello, L., Savage, S. A., Kraft, P., Chanock, S. J., Yeager, M., Landi, M. T., Shi, J., Chatterjee, N. & Amundadottir, L. T., Nov 15 2014, In : Human Molecular Genetics. 23, 24, p. 6616-6633 18 p.

Research output: Contribution to journalArticle

Chromosomes
Alleles
Neoplasms
Genome-Wide Association Study
Telomerase
Pancreatic Neoplasms
Early Detection of Cancer
Neoplasms
Molecular Evolution
Molecular Biology
2013

An Absolute Risk Model to Identify Individuals at Elevated Risk for Pancreatic Cancer in the General Population

Klein, A., Lindström, S., Mendelsohn, J. B., Steplowski, E., Arslan, A. A., Bueno-de-Mesquita, H. B., Fuchs, C. S., Gallinger, S., Gross, M., Helzlsouer, K., Holly, E. A., Jacobs, E. J., LaCroix, A., Li, D., Mandelson, M. T., Olson, S. H., Petersen, G. M., Risch, H. A., Stolzenberg-Solomon, R. Z., Zheng, W. & 42 others, Amundadottir, L., Albanes, D., Allen, N. E., Bamlet, W. R., Boutron-Ruault, M. C., Buring, J. E., Bracci, P. M., Canzian, F., Clipp, S., Cotterchio, M., Duell, E. J., Elena, J., Gaziano, J. M., Giovannucci, E. L., Goggins, M. S., Hallmans, G., Hassan, M., Hutchinson, A., Hunter, D. J., Kooperberg, C., Kurtz, R. C., Liu, S., Overvad, K., Palli, D., Patel, A. V., Rabe, K. G., Shu, X. O., Slimani, N., Tobias, G. S., Trichopoulos, D., Van Den Eeden, S. K., Vineis, P., Virtamo, J., Wactawski-Wende, J., Wolpin, B. M., Yu, H., Yu, K., Zeleniuch-Jacquotte, A., Chanock, S. J., Hoover, R. N., Hartge, P. & Kraft, P., Sep 13 2013, In : PLoS One. 8, 9, e72311.

Research output: Contribution to journalArticle

pancreatic neoplasms
Pancreatic Neoplasms
odds ratio
Odds Ratio
Population

Erratum: The deubiquitinase USP9X suppresses pancreatic ductal adenocarcinoma (Nature (2012) 486 (266-270) DOI: 10.1038/nature11114)

Pérez-Mancera, P. A., Rust, A. G., Van Der Weyden, L., Kristiansen, G., Li, A., Sarver, A. L., Silverstein, K. A. T., Grützmann, R., Aust, D., Rümmele, P., Knösel, T., Herd, C., Stemple, D. L., Kettleborough, R., Brosnan, J. A., Li, A., Morgan, R., Knight, S., Yu, J., Stegeman, S. & 17 others, Collier, L. S., Ten Hoeve, J. J., De Ridder, J., Klein, A., Goggins, M. S., Hruban, R. H., Chang, D. K., Biankin, A. V., Grimmond, S. M., Initiative, A. P. C. G., Wessels, L. F. A., Wood, S. A., Iacobuzio-Donahue, C. A., Pilarsky, C., Largaespada, D. A., Adams, D. J. & Tuveson, D. A., Feb 21 2013, In : Nature. 494, 7437, p. 390 1 p.

Research output: Contribution to journalArticle

Adenocarcinoma
Deubiquitinating Enzymes
Hereditary Neoplastic Syndromes
Pancreatic Neoplasms
Genome
Human Genome
Technology

Identifying people at a high risk of developing pancreatic cancer

Klein, A., Jan 2013, In : Nature Reviews Cancer. 13, 1, p. 66-74 9 p.

Research output: Contribution to journalArticle

Pancreatic Neoplasms
Registries
Cause of Death
Neoplasms
Research

Polymorphisms in genes related to one-carbon metabolism are not related to pancreatic cancer in PanScan and PanC4

Leenders, M., Bhattacharjee, S., Vineis, P., Stevens, V., Bueno-De-Mesquita, H. B., Shu, X. O., Amundadottir, L., Gross, M., Tobias, G. S., Wactawski-Wende, J., Arslan, A. A., Duell, E. J., Fuchs, C. S., Gallinger, S., Hartge, P., Hoover, R. N., Holly, E. A., Jacobs, E. J., Klein, A., Kooperberg, C. & 45 others, Lacroix, A., Li, D., Mandelson, M. T., Olson, S. H., Petersen, G., Risch, H. A., Yu, K., Wolpin, B. M., Zheng, W., Agalliu, I., Albanes, D., Boutron-Ruault, M. C., Bracci, P. M., Buring, J. E., Canzian, F., Chang, K., Chanock, S. J., Cotterchio, M., Gaziano, J. M., Giovanucci, E. L., Goggins, M. S., Hallmans, G., Hankinson, S. E., Hoffman-Bolton, J. A., Hunter, D. J., Hutchinson, A., Jacobs, K. B., Jenab, M., Khaw, K. T., Kraft, P., Krogh, V., Kurtz, R. C., McWilliams, R. R., Mendelsohn, J. B., Patel, A. V., Rabe, K. G., Riboli, E., Tjønneland, A., Trichopoulos, D., Virtamo, J., Visvanathan, K., Elena, J. W., Yu, H., Zeleniuch-Jacquotte, A. & Stolzenberg-Solomon, R. Z., Mar 2013, In : Cancer Causes and Control. 24, 3, p. 595-602 8 p.

Research output: Contribution to journalArticle

Pancreatic Neoplasms
Single Nucleotide Polymorphism
Carbon
Genes
Folic Acid

Prognosis of minimally invasive carcinoma arising in mucinous cystic neoplasms of the pancreas

Lewis, G. H., Wang, H., Bellizzi, A. M., Klein, A., Askin, F. B., Schwartz, L. E., Schulick, R. D., Wolfgang, C., Cameron, J. L., O'Reilly, E. M., Yu, K. H. & Hruban, R. H., Apr 2013, In : American Journal of Surgical Pathology. 37, 4, p. 601-605 5 p.

Research output: Contribution to journalArticle

Pancreatic Neoplasms
Carcinoma
Neoplasms
Adenocarcinoma
Lymph Nodes

Recent progress in pancreatic cancer

Wolfgang, C., Herman, J. M., Laheru, D., Klein, A., Erdek, M., Fishman, E. K. & Hruban, R. H., Sep 2013, In : Ca-A Cancer Journal for Clinicians. 63, 5, p. 318-348 31 p.

Research output: Contribution to journalArticle

Pancreatic Neoplasms
Hope
Drug Combinations
Radiotherapy
Survival
2012

Analysis of polymorphisms and haplotype structure of the human thymidylate synthase genetic region: A tool for pharmacogenetic studies

Ghosh, S., Hossain, M. Z., Borges, M., Goggins, M. S., Ingersoll, R. G., Eshleman, J., Klein, A. & Kern, S. E., Apr 5 2012, In : PLoS One. 7, 4, e34426.

Research output: Contribution to journalArticle

thymidylate synthase
pharmacogenomics
Thymidylate Synthase
Minisatellite Repeats
minisatellite repeats

ATM mutations in patients with hereditary pancreatic cancer

Roberts, N., Jiao, Y., Yu, J., Kopelovich, L., Petersen, G. M., Bondy, M. L., Gallinger, S., Schwartz, A. G., Syngal, S., Cote, M. L., Axilbund, J., Schulick, R., Ali, S. Z., Eshleman, J., Velculescu, V. E., Goggins, M. S., Vogelstein, B., Papadopoulos, N., Hruban, R. H., Kinzler, K. W. & 1 others, Klein, A., Jan 2012, In : Cancer Discovery. 2, 1, p. 41-46 6 p.

Research output: Contribution to journalArticle

Ataxia Telangiectasia
Pancreatic Neoplasms
Mutation
Genes
Adenocarcinoma

Clinical significance of the genetic landscape of pancreatic cancer and implications for identification of potential long-term survivors

Yachida, S., White, C. M., Naito, Y., Zhong, Y., Brosnan, J. A., Macgregor-Das, A. M., Morgan, R. A., Saunders, T., Laheru, D., Herman, J. M., Hruban, R. H., Klein, A., Jones, S., Velculescu, V. E., Wolfgang, C. & Iacobuzio-Donahue, C. A., Nov 15 2012, In : Clinical Cancer Research. 18, 22, p. 6339-6347 9 p.

Research output: Contribution to journalArticle

Pancreatic Neoplasms
Survivors
Genes
Carcinoma
Survival
Tumor-Infiltrating Lymphocytes
Melanoma
Neoplasms
Melanocytes
Nevus

Detectable clonal mosaicism and its relationship to aging and cancer

Jacobs, K. B., Yeager, M., Zhou, W., Wacholder, S., Wang, Z., Rodriguez-Santiago, B., Hutchinson, A., Deng, X., Liu, C., Horner, M. J., Cullen, M., Epstein, C. G., Burdett, L., Dean, M. C., Chatterjee, N., Sampson, J., Chung, C. C., Kovaks, J., Gapstur, S. M., Stevens, V. L. & 169 others, Teras, L. T., Gaudet, M. M., Albanes, D., Weinstein, S. J., Virtamo, J., Taylor, P. R., Freedman, N. D., Abnet, C. C., Goldstein, A. M., Hu, N., Yu, K., Yuan, J. M., Liao, L., Ding, T., Qiao, Y. L., Gao, Y. T., Koh, W. P., Xiang, Y. B., Tang, Z. Z., Fan, J. H., Aldrich, M. C., Amos, C., Blot, W. J., Bock, C. H., Gillanders, E. M., Harris, C. C., Haiman, C. A., Henderson, B. E., Kolonel, L. N., Le Marchand, L., McNeill, L. H., Rybicki, B. A., Schwartz, A. G., Signorello, L. B., Spitz, M. R., Wiencke, J. K., Wrensch, M., Wu, X., Zanetti, K. A., Ziegler, R. G., Figueroa, J. D., Garcia-Closas, M., Malats, N., Marenne, G., Prokunina-Olsson, L., Baris, D., Schwenn, M., Johnson, A., Landi, M. T., Goldin, L., Consonni, D., Bertazzi, P. A., Rotunno, M., Rajaraman, P., Andersson, U., Freeman, L. E. B., Berg, C. D., Buring, J. E., Butler, M. A., Carreon, T., Feychting, M., Ahlbom, A., Gaziano, J. M., Giles, G. G., Hallmans, G., Hankinson, S. E., Hartge, P., Henriksson, R., Inskip, P. D., Johansen, C., Landgren, A., McKean-Cowdin, R., Michaud, D. S., Melin, B. S., Peters, U., Ruder, A. M., Sesso, H. D., Severi, G., Shu, X. O., Visvanathan, K., White, E., Wolk, A., Zeleniuch-Jacquotte, A., Zheng, W., Silverman, D. T., Kogevinas, M., Gonzalez, J. R., Villa, O., Li, D., Duell, E. J., Risch, H. A., Olson, S. H., Kooperberg, C., Wolpin, B. M., Jiao, L., Hassan, M., Wheeler, W., Arslan, A. A., Bueno-De-Mesquita, H. B., Fuchs, C. S., Gallinger, S., Gross, M. D., Holly, E. A., Klein, A., Lacroix, A., Mandelson, M. T., Petersen, G., Boutron-Ruault, M. C., Bracci, P. M., Canzian, F., Chang, K., Cotterchio, M., Giovannucci, E. L., Goggins, M. S., Bolton, J. A. H., Jenab, M., Khaw, K. T., Krogh, V., Kurtz, R. C., McWilliams, R. R., Mendelsohn, J. B., Rabe, K. G., Riboli, E., Tjønneland, A., Tobias, G. S., Trichopoulos, D., Elena, J. W., Yu, H., Amundadottir, L., Stolzenberg-Solomon, R. Z., Kraft, P., Schumacher, F., Stram, D., Savage, S. A., Mirabello, L., Andrulis, I. L., Wunder, J. S., García, A. P., Sierrasesà maga, L., Barkauskas, D. A., Gorlick, R. G., Purdue, M., Chow, W. H., Moore, L. E., Schwartz, K. L., Davis, F. G., Hsing, A. W., Berndt, S. I., Black, A., Wentzensen, N., Brinton, L. A., Lissowska, J., Peplonska, B., McGlynn, K. A., Cook, M. B., Graubard, B. I., Kratz, C. P., Greene, M. H., Erickson, R. L., Hunter, D. J., Thomas, G., Hoover, R. N., Real, F. X., Fraumeni, J. F., Caporaso, N. E., Tucker, M., Rothman, N., Pérez-Jurado, L. A. & Chanock, S. J., Jun 2012, In : Nature Genetics. 44, 6, p. 651-658 8 p.

Research output: Contribution to journalArticle

Mosaicism
Neoplasms
Odds Ratio
DNA
Cheek

Expression of Yes-associated protein modulates Survivin expression in primary liver malignancies

Bai, H., Gayyed, M. F., Lam-Himlin, D. M., Klein, A., Nayar, S. K., Xu, Y., Khan, M., Argani, P., Pan, D. & Anders, R. A., Sep 2012, In : Human Pathology. 43, 9, p. 1376-1385 10 p.

Research output: Contribution to journalArticle

Cholangiocarcinoma
Liver
Hepatocellular Carcinoma
Neoplasms
Proteins

Frequent detection of pancreatic lesions in asymptomatic high-risk individuals

Canto, M., Hruban, R. H., Fishman, E. K., Kamel, I. R., Schulick, R., Zhang, Z., Topazian, M., Takahashi, N., Fletcher, J., Petersen, G., Klein, A., Axilbund, J., Griffin, C., Syngal, S., Saltzman, J. R., Mortele, K. J., Lee, J., Tamm, E., Vikram, R., Bhosale, P. & 3 others, Margolis, D., Farrell, J. & Goggins, M. S., Apr 2012, In : Gastroenterology. 142, 4, p. 796-804 9 p.

Research output: Contribution to journalArticle

Pancreatic Neoplasms
Endosonography
Germ-Line Mutation
Pancreatic Ducts
Cysts

Genetic susceptibility to pancreatic cancer

Klein, A., Jan 2012, In : Molecular Carcinogenesis. 51, 1, p. 14-24 11 p.

Research output: Contribution to journalArticle

Genetic Predisposition to Disease
Pancreatic Neoplasms
Neoplasm Genes
BRCA2 Gene
Penetrance

Genome-wide somatic copy number alterations in low-grade panINs and IPMNs from individuals with a family history of pancreatic cancer

Hong, S. M., Vincent, A., Kanda, M., Leclerc, J., Omura, N., Borges, M., Klein, A., Canto, M., Hruban, R. H. & Goggins, M. S., Aug 15 2012, In : Clinical Cancer Research. 18, 16, p. 4303-4312 10 p.

Research output: Contribution to journalArticle

Pancreatic Neoplasms
Genome
Neoplasms
Single Nucleotide Polymorphism
Primitive Neuroectodermal Tumors

Identification of germline genomic copy number variation in familial pancreatic cancer

Al-Sukhni, W., Joe, S., Lionel, A. C., Zwingerman, N., Zogopoulos, G., Marshall, C. R., Borgida, A., Holter, S., Gropper, A., Moore, S., Bondy, M., Klein, A., Petersen, G. M., Rabe, K. G., Schwartz, A. G., Syngal, S., Scherer, S. W. & Gallinger, S., Sep 2012, In : Human Genetics. 131, 9, p. 1481-1494 14 p.

Research output: Contribution to journalArticle

Pancreatic Neoplasms
Genes
Adenocarcinoma
Genetic Predisposition to Disease
Pancreas

Pathway analysis of genome-wide association study data highlights pancreatic development genes as susceptibility factors for pancreatic cancer

Li, D., Duell, E. J., Yu, K., Risch, H. A., Olson, S. H., Kooperberg, C., Wolpin, B. M., Jiao, L., Dong, X., Wheeler, B., Arslan, A. A., Bueno-de-Mesquita, H. B., Fuchs, C. S., Gallinger, S., Gross, M., Hartge, P., Hoover, R. N., Holly, E. A., Jacobs, E. J., Klein, A. & 43 others, LaCroix, A., Mandelson, M. T., Petersen, G., Zheng, W., Agalliu, I., Albanes, D., Boutron-Ruault, M. C., Bracci, P. M., Buring, J. E., Canzian, F., Chang, K., Chanock, S. J., Cotterchio, M., Gaziano, J. M., Giovannucci, E. L., Goggins, M. S., Hallmans, G., Hankinson, S. E., Hoffman Bolton, J. A., Hunter, D. J., Hutchinson, A., Jacobs, K. B., Jenab, M., Khaw, K. T., Kraft, P., Krogh, V., Kurtz, R. C., Robert, R. M., Mendelsohn, J. B., Patel, A. V., Rabe, K. G., Riboli, E., Shu, X. O., Tjønneland, A., Tobias, G. S., Trichopoulos, D., Virtamo, J., Visvanathan, K., Watters, J., Yu, H., Zeleniuch-Jacquotte, A., Amundadottir, L. & Stolzenberg-Solomon, R. Z., Jul 2012, In : Carcinogenesis. 33, 7, p. 1384-1390 7 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Pancreatic Neoplasms
Genes
Apoptosis
Pylorus

Serotonin expression in pancreatic neuroendocrine tumors correlates with a trabecular histologic pattern and large duct involvement

McCall, C. M., Shi, C., Klein, A., Konukiewitz, B., Edil, B. H., Ellison, T. A., Wolfgang, C., Schulick, R. D., Klöppel, G. & Hruban, R. H., Aug 2012, In : Human Pathology. 43, 8, p. 1169-1176 8 p.

Research output: Contribution to journalArticle

Neuroendocrine Tumors
Serotonin
Fibrosis
Neoplasm Antibodies
Neoplasms

The deubiquitinase USP9X suppresses pancreatic ductal adenocarcinoma

Pérez-Mancera, P. A., Rust, A. G., Van Der Weyden, L., Kristiansen, G., Li, A., Sarver, A. L., Silverstein, K. A. T., Grützmann, R., Aust, D., Rümmele, P., Knösel, T., Herd, C., Stemple, D. L., Kettleborough, R., Brosnan, J. A., Li, A., Morgan, R., Knight, S., Yu, J., Stegeman, S. & 135 others, Collier, L. S., Ten Hoeve, J. J., De Ridder, J., Klein, A., Goggins, M. S., Hruban, R. H., Chang, D. K., Biankin, A. V. W., Grimmond, S. M., Wessels, L. F. A., Wood, S. A., Iacobuzio-Donahue, C. A., Pilarsky, C., Largaespada, D. A., Adams, D. J., Tuveson, D. A., Bienkin, A. V., Johns, A. L., Mawson, A., Cheng, D. K., Brancato, M. A. L., Rowe, S. J., Simpson, S. L., Martyn-Smith, M., Chantrill, L. A., Chin, V. T., Chou, A., Cowley, M. J., Humphris, J. L., Jones, M. D., Scott Mead, R., Nagrial, A. M., Pajic, M., Pettit, J., Pinese, M., Rooman, I., Wu, J., Daly, R. J., Musgrove, E. A., Sutherland, R. L., Grimond, S. M., Waddell, N., Kassahn, K. S., Miller, D. K., Wilson, P. J., Patch, A. M., Song, S., Harliwong, I., Idrisoglu, S., Nourse, C., Nourbakhsh, E., Manning, S., Wani, S., Gongora, M., Anderson, M., Holmes, O., Leonard, C., Taylor, D., Wood, S., Xu, C., Nones, K., Lynn Fink, J., Christ, A., Bruxner, T., Cloonan, N., Newell, F., Pearson, J. V., Samra, J. S., Gill, A. J., Pavlakis, N., Guminski, A., Toon, C., Blankin, A. V., Asghari, R., Merrett, N. D., Pavey, D. A., Das, A., Cosman, P. H., Ismail, K., O'Connor, C., Lam, V. W., McLeod, D., Pleass, H. C., James, V., Kench, J. G., Cooper, C. L., Joseph, D., Sandroussi, C., Crawford, M., Texler, M., Forrest, C., Laycock, A., Epari, K. P., Ballal, M., Fletcher, D. R., Mukhedkar, S., Spry, N. A., Deboer, B., Chai, M., Feeney, K., Zeps, N., Beilin, M., Nguyen, N. Q., Ruszkiewicz, A. R., Worthley, C., Tan, C. P., Debrencini, T., Chen, J., Brooke-Smith, M. E., Papangelis, V., Tang, H., Barbour, A. P., Clouston, A. D., Martin, P., O'Rourke, T. J., Chiang, A., Fawcett, J. W., Slater, K., Yeung, S., Hatzifotis, M., Hodgkinson, P., Christophi, C., Nikfarjam, M., Cancer Biobank, V., Eshleman, J., Maitra, A., Schulick, R. D., Wolfgang, C., Morgan, R. A., Lawlor, R. T., Beghelli, S., Corbo, V., Scardoni, M., Bassi, C. & Tempero, M. A., Jun 14 2012, In : Nature. 486, 7402, p. 266-270 5 p.

Research output: Contribution to journalArticle

Adenocarcinoma
Neoplasms
trichostatin A
Carcinogenesis
Anoikis
2011

Altered telomeres in tumors with ATRX and DAXX mutations

Heaphy, C. M., De Wilde, R. F., Jiao, Y., Klein, A. P., Edil, B. H., Shi, C., Bettegowda, C., Rodriguez, F. J., Eberhart, C. G., Hebbar, S., Offerhaus, G. J., McLendon, R., Rasheed, B. A., He, Y., Yan, H., Bigner, D. D., Oba-Shinjo, S. M., Marie, S. K. N., Riggins, G. J., Kinzler, K. W. & 5 others, Vogelstein, B., Hruban, R. H., Maitra, A., Papadopoulos, N. & Meeker, A. K., Jul 22 2011, In : Science. 333, 6041, p. 425 1 p.

Research output: Contribution to journalArticle

Signal Transducing Adaptor Proteins
DNA Helicases
Neuroendocrine Carcinoma
Central Nervous System Neoplasms
Chromatin Assembly and Disassembly

Current gene discovery strategies for ocular conditions

Duggal, P., Ibay, G. & Klein, A., Sep 2011, In : Investigative Ophthalmology and Visual Science. 52, 10, p. 7761-7770 10 p.

Research output: Contribution to journalArticle

Genetic Linkage
Eye Diseases
Genetic Association Studies
Genomics

Identification of functional genetic variation in exome sequence analysis

Jaffe, A., Wojcik, G., Chu, A., Golozar, A., Maroo, A., Duggal, P. & Klein, A. P., 2011, In : BMC Proceedings. 5, SUPPL. 9, S13.

Research output: Contribution to journalArticle

Exome
Sequence Analysis
Genes
Genome
Information Storage and Retrieval

Linkage analysis of quantitative refraction and refractive errors in the beaver dam eye study

Klein, A., Duggal, P., Lee, K. E., Cheng, C. Y., Klein, R., Bailey-Wilson, J. E. & Klein, B. E. K., Jul 2011, In : Investigative Ophthalmology and Visual Science. 52, 8, p. 5220-5225 6 p.

Research output: Contribution to journalArticle

Refractive Errors
Myopia
Hyperopia
Rodentia
Genome

Personalizing cancer treatment in the age of global genomic analyses: PALB2 gene mutations and the response to DNA damaging agents in pancreatic cancer

Villarroel, M. C., Rajeshkumar, N. V., Garrido-Laguna, I., De Jesus-Acosta, A., Jones, S., Maitra, A., Hruban, R. H., Eshleman, J., Klein, A., Laheru, D., Donehower, R. C. & Hidalgo, M., Jan 2011, In : Molecular Cancer Therapeutics. 10, 1, p. 3-8 6 p.

Research output: Contribution to journalArticle

Pancreatic Neoplasms
Mutation
DNA
Genes
Neoplasms

Recurrent GNAS mutations define an unexpected pathway for pancreatic cyst development

Wu, J., Matthaei, H., Maitra, A., Dal Molin, M., Wood, L. D., Eshleman, J., Goggins, M. S., Canto, M., Schulick, R. D., Edil, B. H., Wolfgang, C., Klein, A., Diaz, L. A., Allen, P. J., Schmidt, C. M., Kinzler, K. W., Papadopoulos, N., Hruban, R. H. & Vogelstein, B., Jul 20 2011, In : Science Translational Medicine. 3, 92, 92ra66.

Research output: Contribution to journalArticle

Pancreatic Cyst
Mutation
Adenocarcinoma
Pancreatic Neoplasms
Neoplasms

Risk factors of familial pancreatic cancer in Japan: Current smoking and recent onset of diabetes

Matsubayashi, H., Maeda, A., Kanemoto, H., Uesaka, K., Yamazaki, K., Hironaka, S., Miyagi, Y., Ikehara, H., Ono, H., Klein, A. & Goggins, M. S., Aug 2011, In : Pancreas. 40, 6, p. 974-978 5 p.

Research output: Contribution to journalArticle

Pancreatic Neoplasms
Japan
Smoking
Odds Ratio
Diabetes Mellitus

Whole-exome sequencing of neoplastic cysts of the pancreas reveals recurrent mutations in components of ubiquitin-dependent pathways

Wu, J., Jiao, Y., Dal Molin, M., Maitra, A., De Wilde, R. F., Wood, L. D., Eshleman, J., Goggins, M. S., Wolfgang, C., Canto, M., Schulick, R. D., Edil, B. H., Choti, M. A., Adsay, V., Klimstra, D. S., Offerhaus, G. J. A., Klein, A., Kopelovich, L., Carter, H., Karchin, R. & 8 others, Allen, P. J., Schmidt, C. M., Naito, Y., Diaz, L. A., Kinzler, K. W., Papadopoulos, N., Hruban, R. H. & Vogelstein, B., Dec 27 2011, In : Proceedings of the National Academy of Sciences of the United States of America. 108, 52, p. 21188-21193 6 p.

Research output: Contribution to journalArticle

Exome
Ubiquitin
Cysts
Pancreas
Mutation
2010
Blood Group Antigens
Pancreatic Neoplasms
Genome-Wide Association Study
Genes
Telomerase

A genome-wide association study identifies pancreatic cancer susceptibility loci on chromosomes 13q22.1, 1q32.1 and 5p15.33

Petersen, G. M., Amundadottir, L., Fuchs, C. S., Kraft, P., Stolzenberg-Solomon, R. Z., Jacobs, K. B., Arslan, A. A., Bueno-De-Mesquita, H. B., Gallinger, S., Gross, M., Helzlsouer, K., Holly, E. A., Jacobs, E. J., Klein, A., Lacroix, A., Li, D., Mandelson, M. T., Olson, S. H., Risch, H. A., Zheng, W. & 53 others, Albanes, D., Bamlet, W. R., Berg, C. D., Boutron-Ruault, M. C., Buring, J. E., Bracci, P. M., Canzian, F., Clipp, S., Cotterchio, M., De Andrade, M., Duell, E. J., Gaziano, J. M., Giovannucci, E. L., Goggins, M. S., Hallmans, G., Hankinson, S. E., Hassan, M., Howard, B., Hunter, D. J., Hutchinson, A., Jenab, M., Kaaks, R., Kooperberg, C., Krogh, V., Kurtz, R. C., Lynch, S. M., McWilliams, R. R., Mendelsohn, J. B., Michaud, D. S., Parikh, H., Patel, A. V., Peeters, P. H. M., Rajkovic, A., Riboli, E., Rodriguez, L., Seminara, D., Shu, X. O., Thomas, G., Tjønneland, A., Tobias, G. S., Trichopoulos, D., Van Den Eeden, S. K., Virtamo, J., Wactawski-Wende, J., Wang, Z., Wolpin, B. M., Yu, H., Yu, K., Zeleniuch-Jacquotte, A., Fraumeni, J. F., Hoover, R. N., Hartge, P. & Chanock, S. J., Mar 2010, In : Nature Genetics. 42, 3, p. 224-228 5 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Pancreatic Neoplasms
Single Nucleotide Polymorphism
Chromosomes
Alleles

Importance of age of onset in pancreatic cancer kindreds

Brune, K. A., Lau, B. M., Palmisano, E., Canto, M., Goggins, M. S., Hruban, R. H. & Klein, A., Jan 2010, In : Journal of the National Cancer Institute. 102, 2, p. 119-126 8 p.

Research output: Contribution to journalArticle

Pancreatic Neoplasms
Age of Onset
Neoplasms
Incidence
Population Surveillance

Update on familial pancreatic cancer

Hruban, R. H., Canto, M., Goggins, M. S., Schulick, R. & Klein, A., Sep 2010, In : Advances in Surgery. 44, 1, p. 293-311 19 p.

Research output: Contribution to journalArticle

Pancreatic Ductal Carcinoma
BRCA2 Gene
Peutz-Jeghers Syndrome
p16 Genes
Fanconi Anemia
2009

Absence of deleterious palladin mutations in patients with familial pancreatic cancer

Klein, A., Borges, M., Griffith, M., Brune, K., Hong, S. M., Omura, N., Hruban, R. H. & Goggins, M. S., Apr 2009, In : Cancer Epidemiology Biomarkers and Prevention. 18, 4, p. 1328-1330 3 p.

Research output: Contribution to journalArticle

Pancreatic Neoplasms
Mutation
Genes
Germ-Line Mutation

Absence of germline BRCA1 mutations in familial pancreatic cancer patients

Axilbund, J. E., Argani, P., Kamiyama, M., Palmisano, E., Raben, M., Borges, M., Brune, K. A., Goggins, M. S., Hruban, R. H. & Klein, A., Jan 2009, In : Cancer Biology and Therapy. 8, 2, p. 131-135 5 p.

Research output: Contribution to journalArticle

Germ-Line Mutation
Pancreatic Neoplasms
BRCA1 Gene
Ovarian Neoplasms
Breast Neoplasms

DPC4 gene status of the primary carcinoma correlates with patterns of failure in patients with pancreatic cancer

Lacobuzio-Donahue, C. A., Fu, B., Yachida, S., Luo, M., Abe, H., Henderson, C. M., Vilardell, F., Wang, Z., Keller, J. W., Banerjee, P., Herman, J. M., Cameron, J. L., Yeo, C. J., Halushka, M. K., Eshleman, J., Raben, M., Klein, A., Hruban, R. H., Hidalgo, M. & Laheru, D., Apr 10 2009, In : Journal of Clinical Oncology. 27, 11, p. 1806-1813 8 p.

Research output: Contribution to journalArticle

Pancreatic Neoplasms
Carcinoma
Autopsy
Genes
p53 Genes

Elevated cancer mortality in the relatives of patients with pancreatic cancer

Wang, L., Brune, K. A., Visvanathan, K., Laheru, D., Herman, J., Wolfgang, C., Schulick, R., Cameron, J. L., Goggins, M. S., Hruban, R. H. & Klein, A., Nov 2009, In : Cancer Epidemiology Biomarkers and Prevention. 18, 11, p. 2829-2834 6 p.

Research output: Contribution to journalArticle

Pancreatic Neoplasms
Mortality
Neoplasms
Registries
Spouses

EPHA2 is associated with age-related cortical cataract in mice and humans

Jun, G., Guo, H., Klein, B. E. K., Klein, R., Jie, J. W., Mitchell, P., Miao, H., Lee, K. E., Joshi, T., Buck, M., Chugha, P., Bardenstein, D., Klein, A., Bailey-Wilson, J. E., Gong, X., Spector, T. D., Andrew, T., Hammond, C. J., Elston, R. C., Iyengar, S. K. & 1 others, Wang, B., Jul 2009, In : PLoS Genetics. 5, 7, e1000584.

Research output: Contribution to journalArticle

cataract
Cataract
mice
protein
blindness

Exomic sequencing identifies PALB2 as a pancreatic cancer susceptibility gene

Jones, S., Hruban, R. H., Kamiyama, M., Borges, M., Zhang, X., Parsons, D. W., Lin, J. C. H., Palmisano, E., Brune, K., Jaffee, E., Iacobuzio-Donahue, C. A., Maitra, A., Parmigiani, G., Kern, S. E., Velculescu, V. E., Kinzler, K. W., Vogelstein, B., Eshleman, J., Goggins, M. S. & Klein, A., Apr 10 2009, In : Science. 324, 5924, p. 217 1 p.

Research output: Contribution to journalArticle

Tumor Suppressor Proteins
identification method
Germ-Line Mutation
Terminator Codon
Sequence Deletion

Familial pancreatic cancer

Shi, C., Hruban, R. H. & Klein, A., Mar 2009, In : Archives of Pathology and Laboratory Medicine. 133, 3, p. 365-374 10 p.

Research output: Contribution to journalArticle

Pancreatic Neoplasms
Dysplastic Nevus Syndrome
Peutz-Jeghers Syndrome
Information Storage and Retrieval
Genetic Testing

Genetic mutations associated with Cigarette smoking in pancreatic cancer

Blackford, A., Parmigiani, G., Kensler, T. W., Wolfgang, C., Jones, S., Zhang, X., Parsons, D. W., Lin, J. C. H., Leary, R. J., Eshleman, J., Goggins, M. S., Jaffee, E., Iacobuzio-Donahue, C. A., Maitra, A., Klein, A., Cameron, J. L., Olino, K., Schulick, R., Winter, J., Vogelstein, B. & 3 others, Velculescu, V. E., Kinzler, K. W. & Hruban, R. H., Apr 15 2009, In : Cancer Research. 69, 8, p. 3681-3688 8 p.

Research output: Contribution to journalArticle

Pancreatic Neoplasms
Smoking
Mutation
Tobacco Products
Carcinoma

Genome-wide association study identifies variants in the ABO locus associated with susceptibility to pancreatic cancer

Amundadottir, L., Kraft, P., Stolzenberg-Solomon, R. Z., Fuchs, C. S., Petersen, G. M., Arslan, A. A., Bueno-De-Mesquita, H. B., Gross, M., Helzlsouer, K., Jacobs, E. J., LaCroix, A., Zheng, W., Albanes, D., Bamlet, W., Berg, C. D., Berrino, F., Bingham, S., Buring, J. E., Bracci, P. M., Canzian, F. & 51 others, Clavel-Chapelon, F., Clipp, S., Cotterchio, M., De Andrade, M., Duell, E. J., Fox, J. W., Gallinger, S., Gaziano, J. M., Giovannucci, E. L., Goggins, M. S., González, C. A., Hallmans, G., Hankinson, S. E., Hassan, M., Holly, E. A., Hunter, D. J., Hutchinson, A., Jackson, R., Jacobs, K. B., Jenab, M., Kaaks, R., Klein, A., Kooperberg, C., Kurtz, R. C., Li, D., Lynch, S. M., Mandelson, M., McWilliams, R. R., Mendelsohn, J. B., Michaud, D. S., Olson, S. H., Overvad, K., Patel, A. V., Peeters, P. H. M., Rajkovic, A., Riboli, E., Risch, H. A., Shu, X. O., Thomas, G., Tobias, G. S., Trichopoulos, D., Van Den Eeden, S. K., Virtamo, J., Wactawski-Wende, J., Wolpin, B. M., Yu, H., Yu, K., Zeleniuch-Jacquotte, A., Chanock, S. J., Hartge, P. & Hoover, R. N., Sep 2009, In : Nature Genetics. 41, 9, p. 986-990 5 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Pancreatic Neoplasms
Single Nucleotide Polymorphism
Blood Group Antigens
Case-Control Studies

Heritability analysis of spherical equivalent, axial length, corneal curvature, and anterior chamber depth in the Beaver Dam Eye Study

Klein, A., Suktitipat, B., Duggal, P., Lee, K. E., Klein, R., Bailey-Wilson, J. E. & Klein, B. E. K., May 2009, In : Archives of Ophthalmology. 127, 5, p. 649-655 7 p.

Research output: Contribution to journalArticle

Anterior Chamber
Rodentia
Myopia
Sclerosis
Education

Increased prevalence of precursor lesions in familial pancreatic cancer patients

Shi, C., Klein, A., Goggins, M. S., Maitra, A., Canto, M., Ali, S. Z., Schulick, R., Palmisano, E. & Hruban, R. H., Dec 15 2009, In : Clinical Cancer Research. 15, 24, p. 7737-7743 7 p.

Research output: Contribution to journalArticle

Pancreatic Neoplasms
Neoplasms
Pancreas
Confidence Intervals
Research Design