Fingerprint Fingerprint is based on mining the text of the persons scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

Modulators Chemical Compounds
Metabotropic Glutamate 5 Receptor Medicine & Life Sciences
Allosteric Site Medicine & Life Sciences
Fear Medicine & Life Sciences
Pharmacology Medicine & Life Sciences
Pregnanolone Medicine & Life Sciences
Oxadiazoles Medicine & Life Sciences
Arginine Vasopressin Medicine & Life Sciences

Research Output 2004 2013

N-aryl piperazine metabotropic glutamate receptor 5 positive allosteric modulators possess efficacy in preclinical models of NMDA hypofunction and cognitive enhancement

Gregory, K. J. , Herman, E. J. , Ramsey, A. J. , Hammond, A. S. , Byun, N. E. , Stauffer, S. R. , Manka, J. T. , Jadhav, S. , Bridges, T. M. , Weaver, C. D. , Niswender, C. M. , Steckler, T. , Drinkenburg, W. H. , Ahnaou, A. , Lavreysen, H. , Macdonald, G. J. , Bartolomé, J. M. , Mackie, C. , Hrupka, B. J. , Caron, M. G. & 4 others Daigle, T. L., Lindsley, C. W., Conn, P. J. & Jones, C. K. Nov 2013 In : Journal of Pharmacology and Experimental Therapeutics. 347, 2, p. 438-457 20 p.

Research output: Contribution to journalArticle

Metabotropic Glutamate 5 Receptor
Startle Reflex
Allosteric Site

Discovery of a novel chemical class of mGlu5 allosteric ligands with distinct modes of pharmacology

Hammond, A. S., Rodriguez, A. L., Townsend, S. D., Niswender, C. M., Gregory, K. J., Lindsley, C. W. & Conn, P. J. Oct 20 2010 In : ACS Chemical Neuroscience. 1, 10, p. 702-716 15 p.

Research output: Contribution to journalArticle

Allosteric Site
Chemical activation

Synthesis, SAR and unanticipated pharmacological profiles of analogues of the mGluR5 ago-potentiator ADX-47273

Engers, D. W., Rodriguez, A. L., Williams, R., Hammond, A. S., Venable, D., Oluwatola, O., Sulikowski, G. A., Conn, P. J. & Lindsley, C. W. Apr 17 2009 In : ChemMedChem. 4, 4, p. 505-511 7 p.

Research output: Contribution to journalArticle

Glutamic Acid

Sex differences in hormonal modulation of anxiety measured with light-enhanced startle: Possible role for arginine vasopressin in the male

Toufexis, D., Davis, C., Hammond, A. & Davis, M. Sep 28 2005 In : Journal of Neuroscience. 25, 39, p. 9010-9016 7 p.

Research output: Contribution to journalArticle

Arginine Vasopressin
Sex Characteristics

Progesterone attenuates corticotropin-releasing factor-enhanced but not fear-potentiated startle via the activity of its neuroactive metabolite, allopregnanolone

Toufexis, D. J., Davis, C., Hammond, A. & Davis, M. Nov 10 2004 In : Journal of Neuroscience. 24, 45, p. 10280-10287 8 p.

Research output: Contribution to journalArticle

Corticotropin-Releasing Hormone
Intraventricular Infusions