Albena Dinkova Kostova

Associate Professor

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Research Output 1993 2018

C151 in KEAP1 is the main cysteine sensor for the cyanoenone class of NRF2 activators, irrespective of molecular size or shape

Dayalan Naidu, S., Muramatsu, A., Saito, R., Asami, S., Honda, T., Hosoya, T., Itoh, K., Yamamoto, M., Suzuki, T. & Dinkova-Kostova, A. T., Dec 1 2018, In : Scientific Reports. 8, 1, 8037

Research output: Contribution to journalArticle


Experimental Nonalcoholic Steatohepatitis and Liver Fibrosis Are Ameliorated by Pharmacologic Activation of Nrf2 (NF-E2 p45-Related Factor 2)

Sharma, R. S., Harrison, D. J., Kisielewski, D., Cassidy, D. M., McNeilly, A. D., Gallagher, J. R., Walsh, S. V., Honda, T., McCrimmon, R. J., Dinkova-Kostova, A. T., Ashford, M. L. J., Dillon, J. F. & Hayes, J. D., Mar 1 2018, In : CMGH. 5, 3, p. 367-398 32 p.

Research output: Contribution to journalArticle

NF-E2-Related Factor 2
Liver Cirrhosis
Endoplasmic Reticulum Stress

KEAP1 inhibition is neuroprotective and suppresses the development of epilepsy

Shekh-Ahmad, T., Eckel, R., Dayalan Naidu, S., Higgins, M., Yamamoto, M., DInkova-Kostova, A. T., Kovac, S., Abramov, A. Y. & Walker, M. C., May 1 2018, In : Brain. 141, 5, p. 1390-1403 14 p.

Research output: Contribution to journalArticle

Status Epilepticus
Reactive Oxygen Species

The role of Nrf2 signaling in counteracting neurodegenerative diseases

Dinkova-Kostova, A. T., Kostov, R. V. & Kazantsev, A. G., Jan 1 2018, (Accepted/In press) In : FEBS Journal.

Research output: Contribution to journalArticle

Marine biology
Neurodegenerative Diseases
Oxidative Stress
NF-E2 Transcription Factor

Activation of Nrf2 Signaling Augments Vesicular Stomatitis Virus Oncolysis via Autophagy-Driven Suppression of Antiviral Immunity

Olagnier, D., Lababidi, R. R., Hadj, S. B., Sze, A., Liu, Y., Naidu, S. D., Ferrari, M., Jiang, Y., Chiang, C., Beljanski, V., Goulet, M. L., Knatko, E. V., Dinkova-Kostova, A. T., Hiscott, J. & Lin, R., Aug 2 2017, In : Molecular Therapy. 25, 8, p. 1900-1916 17 p.

Research output: Contribution to journalArticle

Vesicular Stomatitis
Antiviral Agents
Oncolytic Viruses