Alban Latremoliere

Assistant Professor


Research output per year

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Research Output


Sepiapterin Reductase Inhibition Leading to Selective Reduction of Inflammatory Joint Pain in Mice and Increased Urinary Sepiapterin Levels in Humans and Mice

Fujita, M., Scheffer, D. D. L., Turnes, B. L., Cronin, S. J. F., Latrémolière, A., Costigan, M., Woolf, C. J., Latini, A. & Andrews, N. A., Jan 1 2020, In : Arthritis and Rheumatology. 72, 1, p. 57-66 10 p.

Research output: Contribution to journalArticle


Natural Killer Cells Degenerate Intact Sensory Afferents following Nerve Injury

Davies, A. J., Kim, H. W., Gonzalez-Cano, R., Choi, J., Back, S. K., Roh, S. E., Johnson, E., Gabriac, M., Kim, M. S., Lee, J., Lee, J. E., Kim, Y. S., Bae, Y. C., Kim, S. J., Lee, K. M., Na, H. S., Riva, P., Latremoliere, A., Rinaldi, S., Ugolini, S. & 2 others, Costigan, M. & Oh, S. B., Feb 7 2019, In : Cell. 176, 4, p. 716-728.e18

Research output: Contribution to journalArticle


Mechanistic Differences in Neuropathic Pain Modalities Revealed by Correlating Behavior with Global Expression Profiling

Cobos, E. J., Nickerson, C. A., Gao, F., Chandran, V., Bravo-Caparrós, I., González-Cano, R., Riva, P., Andrews, N. A., Latremoliere, A., Seehus, C. R., Perazzoli, G., Nieto, F. R., Joller, N., Painter, M. W., Ma, C. H. E., Omura, T., Chesler, E. J., Geschwind, D. H., Coppola, G., Rangachari, M. & 2 others, Woolf, C. J. & Costigan, M., Jan 30 2018, In : Cell Reports. 22, 5, p. 1301-1312 12 p.

Research output: Contribution to journalArticle

Neuronal-Specific TUBB3 Is Not Required for Normal Neuronal Function but Is Essential for Timely Axon Regeneration

Latremoliere, A., Cheng, L., DeLisle, M., Wu, C., Chew, S., Hutchinson, E. B., Sheridan, A., Alexandre, C., Latremoliere, F., Sheu, S. H., Golidy, S., Omura, T., Huebner, E. A., Fan, Y., Whitman, M. C., Nguyen, E., Hermawan, C., Pierpaoli, C., Tischfield, M. A., Woolf, C. J. & 1 others, Engle, E. C., Aug 14 2018, In : Cell Reports. 24, 7, p. 1865-1879.e9

Research output: Contribution to journalArticle

NMDA Receptor Activation Underlies the Loss of Spinal Dorsal Horn Neurons and the Transition to Persistent Pain after Peripheral Nerve Injury

Inquimbert, P., Moll, M., Latremoliere, A., Tong, C. K., Whang, J., Sheehan, G. F., Smith, B. M., Korb, E., Athié, M. C. P., Babaniyi, O., Ghasemlou, N., Yanagawa, Y., Allis, C. D., Hof, P. R. & Scholz, J., May 29 2018, In : Cell Reports. 23, 9, p. 2678-2689 12 p.

Research output: Contribution to journalArticle

Optical cuff for optogenetic control of the peripheral nervous system

Michoud, F., Sottas, L., Browne, L. E., Asboth, L., Latremoliere, A., Sakuma, M., Courtine, G., Woolf, C. J. & Lacour, S. P., Feb 2018, In : Journal of neural engineering. 15, 1, 015002.

Research output: Contribution to journalArticle

The metabolite BH4 controls T cell proliferation in autoimmunity and cancer

Cronin, S. J. F., Seehus, C., Weidinger, A., Talbot, S., Reissig, S., Seifert, M., Pierson, Y., McNeill, E., Longhi, M. S., Turnes, B. L., Kreslavsky, T., Kogler, M., Hoffmann, D., Ticevic, M., da Luz Scheffer, D., Tortola, L., Cikes, D., Jais, A., Rangachari, M., Rao, S. & 21 others, Paolino, M., Novatchkova, M., Aichinger, M., Barrett, L., Latremoliere, A., Wirnsberger, G., Lametschwandtner, G., Busslinger, M., Zicha, S., Latini, A., Robson, S. C., Waisman, A., Andrews, N., Costigan, M., Channon, K. M., Weiss, G., Kozlov, A. V., Tebbe, M., Johnsson, K., Woolf, C. J. & Penninger, J. M., Nov 22 2018, In : Nature. 563, 7732, p. 564-568 5 p.

Research output: Contribution to journalArticle


Arachidonic acid containing phosphatidylcholine increases due to microglial activation in ipsilateral spinal dorsal horn following spared sciatic nerve injury

Banno, T., Omura, T., Masaki, N., Arima, H., Xu, D., Okamoto, A., Costigan, M., Latremoliere, A., Matsuyama, Y. & Setou, M., May 2017, In : PloS one. 12, 5, e0177595.

Research output: Contribution to journalArticle

Combining Human and Rodent Genetics to Identify New Analgesics

Latremoliere, A. & Costigan, M., Jul 1 2017, (Accepted/In press) In : Neuroscience Bulletin. p. 1-13 13 p.

Research output: Contribution to journalArticle

Decreased alertness due to sleep loss increases pain sensitivity in mice

Alexandre, C., Latremoliere, A., Ferreira, A., Miracca, G., Yamamoto, M., Scammell, T. E. & Woolf, C. J., Jun 1 2017, In : Nature Medicine. 23, 6, p. 768-774 7 p.

Research output: Contribution to journalArticle

Time-Resolved Fast Mammalian Behavior Reveals the Complexity of Protective Pain Responses

Browne, L. E., Latremoliere, A., Lehnert, B. P., Grantham, A., Ward, C., Alexandre, C., Costigan, M., Michoud, F., Roberson, D. P., Ginty, D. D. & Woolf, C. J., Jul 5 2017, In : Cell Reports. 20, 1, p. 89-98 10 p.

Research output: Contribution to journalArticle


Ensuring transparency and minimization of methodologic bias in preclinical pain research: PPRECISE considerations

Andrews, N. A., Latrémolière, A., Basbaum, A. I., Mogil, J. S., Porreca, F., Rice, A. S. C., Woolf, C. J., Currie, G. L., Dworkin, R. H., Eisenach, J. C., Evans, S., Gewandter, J. S., Gover, T. D., Handwerker, H., Huang, W., Iyengar, S., Jensen, M. P., Kennedy, J. D., Lee, N., Levine, J. & 14 others, Lidster, K., MacHin, I., McDermott, M. P., McMahon, S. B., Price, T. J., Ross, S. E., Scherrer, G., Seal, R. P., Sena, E. S., Silva, E., Stone, L., Svensson, C. I., Turk, D. C. & Whiteside, G., Apr 1 2016, In : Pain. 157, 4, p. 901-909 9 p.

Research output: Contribution to journalArticle

Inhibition of the kinase WNK1/HSN2 ameliorates neuropathic pain by restoring GABA inhibition

Kahle, K. T., Schmouth, J. F., Lavastre, V., Latremoliere, A., Zhang, J., Andrews, N., Omura, T., Laganière, J., Rochefort, D., Hince, P., Castonguay, G., Gaudet, R., Mapplebeck, J. C. S., Sotocinal, S. G., Duan, J., Ward, C., Khanna, A. R., Mogil, J. S., Dion, P. A., Woolf, C. J. & 2 others, Inquimbert, P. & Rouleau, G. A., Mar 29 2016, In : Science signaling. 9, 421, ra32.

Research output: Contribution to journalArticle

Lack of motor recovery after prolonged denervation of the neuromuscular junction is not due to regenerative failure

Sakuma, M., Gorski, G., Sheu, S. H., Lee, S., Barrett, L. B., Singh, B., Omura, T., Latremoliere, A. & Woolf, C. J., Feb 1 2016, In : European Journal of Neuroscience. 43, 3, p. 451-462 12 p.

Research output: Contribution to journalArticle


Doublecortin-Like Kinases Promote Neuronal Survival and Induce Growth Cone Reformation via Distinct Mechanisms

Nawabi, H., Belin, S., Cartoni, R., Williams, P. R., Wang, C., Latremolière, A., Wang, X., Zhu, J., Taub, D. G., Fu, X., Yu, B., Gu, X., Woolf, C. J., Liu, J. S., Gabel, C. V., Steen, J. A. & He, Z., Nov 18 2015, In : Neuron. 88, 4, p. 704-719 16 p.

Research output: Contribution to journalArticle

Injury-Induced Decline of Intrinsic Regenerative Ability Revealed by Quantitative Proteomics

Belin, S., Nawabi, H., Wang, C., Tang, S., Latremoliere, A., Warren, P., Schorle, H., Uncu, C., Woolf, C. J., He, Z. & Steen, J. A., May 20 2015, In : Neuron. 86, 4, p. 1000-1014 15 p.

Research output: Contribution to journalArticle

Reduction of Neuropathic and Inflammatory Pain through Inhibition of the Tetrahydrobiopterin Pathway

Latremoliere, A., Latini, A., Andrews, N., Cronin, S. J., Fujita, M., Gorska, K., Hovius, R., Romero, C., Chuaiphichai, S., Painter, M., Miracca, G., Babaniyi, O., Remor, A. P., Duong, K., Riva, P., Barrett, L. B., Ferreirós, N., Naylor, A., Penninger, J. M., Tegeder, I. & 6 others, Zhong, J., Blagg, J., Channon, K. M., Johnsson, K., Costigan, M. & Woolf, C. J., Jun 17 2015, In : Neuron. 86, 6, p. 1393-1406 14 p.

Research output: Contribution to journalArticle

Robust Axonal Regeneration Occurs in the Injured CAST/Ei Mouse CNS

Omura, T., Omura, K., Tedeschi, A., Riva, P., Painter, M. W., Rojas, L., Martin, J., Lisi, V., Huebner, E. A., Latremoliere, A., Yin, Y., Barrett, L. B., Singh, B., Lee, S., Crisman, T., Gao, F., Li, S., Kapur, K., Geschwind, D. H., Kosik, K. S. & 6 others, Coppola, G., He, Z., Carmichael, S. T., Benowitz, L. I., Costigan, M. & Woolf, C. J., Jun 3 2015, In : Neuron. 86, 5, p. 1215-1227 13 p.

Research output: Contribution to journalArticle

The serine protease inhibitor SerpinA3N attenuates neuropathic pain by inhibiting T cell-derived leukocyte elastase

Vicuña, L., Strochlic, D. E., Latremoliere, A., Bali, K. K., Simonetti, M., Husainie, D., Prokosch, S., Riva, P., Griffin, R. S., Njoo, C., Gehrig, S., Mall, M. A., Arnold, B., Devor, M., Woolf, C. J., Liberles, S. D., Costigan, M. & Kuner, R., May 1 2015, In : Nature medicine. 21, 5, p. 518-523 6 p.

Research output: Contribution to journalArticle


Diminished Schwann cell repair responses underlie age-associated impaired axonal regeneration

Painter, M. W., Brosius Lutz, A., Cheng, Y. C., Latremoliere, A., Duong, K., Miller, C. M., Posada, S., Cobos, E. J., Zhang, A. X., Wagers, A. J., Havton, L. A., Barres, B., Omura, T. & Woolf, C. J., Jul 16 2014, In : Neuron. 83, 2, p. 331-343 13 p.

Research output: Contribution to journalArticle


Accelerating axonal growth promotes motor recovery after peripheral nerve injury in mice

Ma, C. H. E., Omura, T., Cobos, E. J., Latrémolière, A., Ghasemlou, N., Brenner, G. J., Van Veen, E., Barrett, L., Sawada, T., Gao, F., Coppola, G., Gertler, F., Costigan, M., Geschwind, D. & Woolf, C. J., Nov 1 2011, In : Journal of Clinical Investigation. 121, 11, p. 4332-4347 16 p.

Research output: Contribution to journalArticle

GCH1, BH4 and pain

Latremoliere, A., Costigan, M. & Kirby, F. M., Oct 2011, In : Current Pharmaceutical Biotechnology. 12, 10, p. 1728-1741 14 p.

Research output: Contribution to journalArticle


Differential anti-neuropathic pain effects of tetrodotoxin in sciatic nerve- versus infraorbital nerve-ligated rats - Behavioral, pharmacological and immunohistochemical investigations

Kayser, V., Viguier, F., Ioannidi, M., Bernard, J. F., Latrémolière, A., Michot, B., Vela, J. M., Buschmann, H., Hamon, M. & Bourgoin, S., Feb 1 2010, In : Neuropharmacology. 58, 2, p. 474-487 14 p.

Research output: Contribution to journalArticle


T-cell infiltration and signaling in the adult dorsal spinal cord is a major contributor to neuropathic pain-like hypersensitivity

Costigan, M., Moss, A., Latremoliere, A., Johnston, C., Verma-Gandhu, M., Herbert, T. A., Barrett, L., Brenner, G. J., Vardeh, D., Woolf, C. J. & Fitzgerald, M., Nov 18 2009, In : Journal of Neuroscience. 29, 46, p. 14415-14422 8 p.

Research output: Contribution to journalArticle


Differential implication of proinflammatory cytokine interleukin-6 in the development of cephalic versus extracephalic neuropathic pain in rats

Latrémolière, A., Mauborgne, A., Masson, J., Bourgoin, S., Kayser, V., Hamon, M. & Pohl, M., Aug 20 2008, In : Journal of Neuroscience. 28, 34, p. 8489-8501 13 p.

Research output: Contribution to journalArticle


Immunolabelling of the 5-HT3B receptor subunit in the central and peripheral nervous systems in rodents

Doucet, E., Latrémolière, A., Darmon, M., Hamon, M. & Emerit, M. B., Jul 1 2007, In : European Journal of Neuroscience. 26, 2, p. 355-366 12 p.

Research output: Contribution to journalArticle

Lentiviral-mediated targeted NF-κB blockade in dorsal spinal cord glia attenuates sciatic nerve injury-induced neuropathic pain in the rat

Meunier, A., Latrémolière, A., Dominguez, E., Mauborgne, A., Philippe, S., Hamon, M., Mallet, J., Benoliel, J. J. & Pohl, M., Apr 1 2007, In : Molecular Therapy. 15, 4, p. 687-697 11 p.

Research output: Contribution to journalArticle


Attenuation of pain-related behavior in a rat model of trigeminal neuropathic pain by viral-driven enkephalin overproduction in trigeminal ganglion neurons

Meunier, A., Latrémolière, A., Mauborgne, A., Bourgoin, S., Kayser, V., Cesselin, F., Hamon, M. & Pohl, M., Apr 1 2005, In : Molecular Therapy. 11, 4, p. 608-616 9 p.

Research output: Contribution to journalArticle