Alan Keith Meeker

Associate Professor

1984 …2019
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  • 6 Similar Profiles
Telomere Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Prostatic Neoplasms Medicine & Life Sciences
Telomere Homeostasis Medicine & Life Sciences
Telomerase Medicine & Life Sciences
Telomere Shortening Medicine & Life Sciences
Prostate Medicine & Life Sciences
Micrococcal Nuclease Medicine & Life Sciences

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Research Output 1984 2019

Translational Medical Research
Biomarkers
Prostatic Neoplasms
Telomere
Tissue

A unique telomere DNA expansion phenotype in human retinal rod photoreceptors associated with aging and disease

Bell, W. R., Meeker, A. K., Rizzo, A., Rajpara, S., Rosenthal, I. M., Flores Bellver, M., Aparicio Domingo, S., Zhong, X., Barber, J. R., Joshu, C. E., Canto-Soler, M. V., Eberhart, C. G. & Heaphy, C. M., Jan 1 2019, In : Brain Pathology. 29, 1, p. 45-52 8 p.

Research output: Contribution to journalArticle

Retinal Rod Photoreceptor Cells
Telomere
Phenotype
DNA
Retina

IDH1-R132H acts as a tumor suppressor in glioma via epigenetic up-regulation of the DNA damage response

Núñez, F. J., Mendez, F. M., Kadiyala, P., Alghamri, M. S., Savelieff, M. G., Garcia-Fabiani, M. B., Haase, S., Koschmann, C., Calinescu, A. A., Kamran, N., Saxena, M., Patel, R., Carney, S., Guo, M. Z., Edwards, M., Ljungman, M., Qin, T., Sartor, M. A., Tagett, R., Venneti, S. & 15 others, Brosnan-Cashman, J., Meeker, A. K., Gorbunova, V., Zhao, L., Kremer, D. M., Zhang, L., Lyssiotis, C. A., Jones, L., Herting, C. J., Ross, J. L., Hambardzumyan, D., Hervey-Jumper, S., Figueroa, M. E., Lowenstein, P. R. & Castro, M. G., Feb 13 2019, In : Science translational medicine. 11, 479, eaaq1427.

Research output: Contribution to journalArticle

alpha-Thalassemia
X-Linked Genes
Epigenomics
Glioma
DNA Damage

Molecular Pathology of High-Grade Prostatic Intraepithelial Neoplasia: Challenges and Opportunities

Trabzonlu, L., Kulac, I., Zheng, Q., Hicks, J. L., Haffner, M. C., Nelson, W. G., Sfanos, K., Ertunc, O., Lotan, T., Heaphy, C. M., Meeker, A. K., Yegnasubramanian, S. & Demarzo, A. M., Apr 1 2019, In : Cold Spring Harbor Perspectives in Medicine. 9, 4

Research output: Contribution to journalReview article

Prostatic Intraepithelial Neoplasia
Molecular Pathology
Pathology
Prostatic Neoplasms
Carcinoma in Situ

Telomere Dysfunction Induces Sirtuin Repression that Drives Telomere-Dependent Disease

Amano, H., Chaudhury, A., Rodriguez-Aguayo, C., Lu, L., Akhanov, V., Catic, A., Popov, Y. V., Verdin, E., Johnson, H., Stossi, F., Sinclair, D. A., Nakamaru-Ogiso, E., Lopez-Berestein, G., Chang, J. T., Neilson, J. R., Meeker, A. K., Finegold, M., Baur, J. A. & Sahin, E., Jun 4 2019, In : Cell Metabolism. 29, 6, p. 1274-1290.e9

Research output: Contribution to journalArticle

Sirtuins
Telomere
Telomere Shortening
NAD
DNA Damage