1967 …2018
If you made any changes in Pure, your changes will be visible here soon.

Research Output 1967 2018

2018

Consensus statement on the need for innovation, transition and implementation of developmental neurotoxicity (DNT) testing for regulatory purposes

Fritsche, E., Grandjean, P., Crofton, K. M., Aschner, M., Goldberg, A., Heinonen, T., Hessel, E. V. S., Hogberg, H., Bennekou, S. H., Lein, P. J., Leist, M., Mundy, W. R., Paparella, M., Piersma, A. H., Sachana, M., Schmuck, G., Solecki, R., Terron, A., Monnet-Tschudi, F., Wilks, M. F. & 3 others, Witters, H., Zurich, M. G. & Bal-Price, A., Jan 1 2018, (Accepted/In press) In : Toxicology and Applied Pharmacology.

Research output: Contribution to journalArticle

Consensus
Innovation
Needs Assessment
Environmental Exposure
Testing
2017

Foreword

Goldberg, A., Jan 1 2017, Alternatives for Dermal Toxicity Testing. Springer International Publishing, p. v-vii

Research output: Chapter in Book/Report/Conference proceedingForeword/postscript

From in vivo to in vitro: The medical device testing paradigm shift

Myers, D. K., Goldberg, A., Poth, A., Wolf, M. F., Carraway, J., McKim, J., Coleman, K. P., Hutchinson, R., Brown, R., Krug, H. F., Bahinski, A. & Hartung, T., Jan 1 2017, In : Altex. 34, 4, p. 479-500 22 p.

Research output: Contribution to journalArticle

Equipment and Supplies
Animal Testing Alternatives
Toxicity Tests
Practice Guidelines
Industry
2016

Farm Animal Welfare and Human Health

Goldberg, A., Sep 1 2016, In : Current environmental health reports. 3, 3, p. 313-321 9 p.

Research output: Contribution to journalReview article

Animal Welfare
Domestic Animals
Health
Meat
Fishes
2014

Consensus report on the future of animal-free systemic toxicity testing

Leist, M., Hasiwa, N., Rovida, C., Daneshian, M., Basketter, D., Kimber, I., Clewell, H., Gocht, T., Goldberg, A., Busquet, F., Rossi, A. M., Schwarz, M., Stephens, M. L., Taalman, R., Knudsen, T. B., McKim, J., Harris, G., Pamies, D. & Hartung, T., 2014, In : Altex. 31, 3, p. 341-356 16 p.

Research output: Contribution to journalArticle

Consensus
Systems Biology
Information Dissemination
Cosmetics
Hypersensitivity

Green toxicology

Maertens, A., Anastas, N., Spencer, P. J., Stephens, M. L., Goldberg, A. & Hartung, T., 2014, In : Altex. 31, 3, p. 243-249 7 p.

Research output: Contribution to journalArticle

Toxicology
Computer Simulation
Forensic Toxicology
Ecotoxicology
Organizational Culture

State-of-the-art of 3D cultures (Organs-on-a-Chip) in safety testing and pathophysiology

Alépée, N., Bahinski, A., Daneshian, M., De Wever, B., Fritsche, E., Goldberg, A., Hansmann, J., Hartung, T., Haycock, J., Hogberg, H., Hoelting, L., Kelm, J. M., Kadereit, S., McVey, E., Landsiedel, R., Leist, M., Lübberstedt, M., Noor, F., Pellevoisin, C., Petersohn, D. & 7 others, Pfannenbecker, U., Reisinger, K., Ramirez, T., Rothen-Rutishauser, B., Schäfer-Korting, M., Zeilinger, K. & Zurich, M. G., 2014, In : Archivos de Medicina Veterinaria. 46, 4, p. 441-477 37 p.

Research output: Contribution to journalArticle

safety testing
organ culture
Organ Culture Techniques
pathophysiology
Safety
2012

Advancing the science of developmental neurotoxicity (DNT): Testing for better safety evaluation

Bal-Price, A. K., Coecke, S., Costa, L., Crofton, K. M., Fritsche, E., Goldberg, A., Grandjean, P., Lein, P. J., Li, A., Lucchini, R., Mundy, W. R., Padilla, S., Persico, A. M., Seiler, A. E. M. & Kreysa, J., 2012, In : Altex. 29, 2, p. 202-215 14 p.

Research output: Contribution to journalArticle

A roadmap for the development of alternative (non-animal) methods for systemic toxicity testing

Basketter, D. A., Clewell, H., Kimber, I., Rossi, A., Blaauboer, B., Burrier, R., Daneshian, M., Eskes, C., Goldberg, A., Hasiwa, N., Hoffmann, S., Jaworska, J., Knudsen, T. B., Landsiedel, R., Leist, M., Locke, P., Maxwell, G., McKim, J., McVey, E. A., Ouédraogo, G. & 15 others, Patlewicz, G., Pelkonen, O., Roggen, E., Rovida, C., Ruhdel, I., Schwarz, M., Schepky, A., Schoeters, G., Skinner, N., Trentz, K., Turner, M., Vanparys, P., Yager, J. D., Zurlo, J. & Hartung, T., 2012, In : Altex. 29, 1, p. 5-91 87 p.

Research output: Contribution to journalArticle

Animal Welfare
Cell- and Tissue-Based Therapy
Marketing
Cosmetics
Nanoparticles

A roadmap for the development of alternative (non-animal) methods for systemic toxicity testing - t4 report*.

Basketter, D. A., Clewell, H., Kimber, I., Rossi, A., Blaauboer, B., Burrier, R., Daneshian, M., Eskes, C., Goldberg, A., Hasiwa, N., Hoffmann, S., Jaworska, J., Knudsen, T. B., Landsiedel, R., Leist, M., Locke, P., Maxwell, G., McKim, J., McVey, E. A., Ouédraogo, G. & 15 others, Patlewicz, G., Pelkonen, O., Roggen, E., Rovida, C., Ruhdel, I., Schwarz, M., Schepky, A., Schoeters, G., Skinner, N., Trentz, K., Turner, M., Vanparys, P., Yager, J. D., Zurlo, J. & Hartung, T., 2012, In : Altex. 29, 1, p. 3-91 89 p.

Research output: Contribution to journalArticle

Animal Welfare
Cell- and Tissue-Based Therapy
Marketing
Cosmetics
Nanoparticles

The use of biomarkers of toxicity for integrating in vitro hazard estimates into risk assessment for humans

Blaauboer, B. J., Boekelheide, K., Clewell, H. J., Daneshian, M., Dingemans, M. M. L., Goldberg, A., Heneweer, M., Jaworska, J., Kramer, N. I., Leist, M., Seibert, H., Testai, E., Vandebriel, R. J., Yager, J. D. & Zurlo, J., 2012, In : Altex. 29, 4, p. 411-425 15 p.

Research output: Contribution to journalArticle

Biomarkers
In Vitro Techniques
Toxicology
Education
2011

A framework program for the teaching of alternative methods (replacement, reduction, refinement) to animal experimentation

Daneshian, M., Akbarsha, M. A., Blaauboer, B., Caloni, F., Cosson, P., Curren, R., Goldberg, A., Gruber, F., Ohl, F., Pfaller, W., Van Der Valk, J., Vinardell, P., Zurlo, J., Hartung, T. & Leist, M., 2011, In : Altex. 28, 4, p. 341-352 12 p.

Research output: Contribution to journalArticle

Teaching
Education
Toxicology
Animal Use Alternatives
Animal Testing Alternatives

Developmental neurotoxicity testing: Recommendations for developing alternative methods for the screening and prioritization of chemicals

Crofton, K. M., Mundy, W. R., Lein, P. J., Bal-Price, A., Coecke, S., Seiler, A. E. M., Knaut, H., Buzanska, L. & Goldberg, A., 2011, In : Altex. 28, 1, p. 9-15 7 p.

Research output: Contribution to journalArticle

Social Planning
Guidelines
Education
Research

Food for thought... on validation. A puzzle or a mystery: An approach founded on new science

Wilcox, N. & Goldberg, A., 2011, In : Altex. 28, 1, p. 3-8 6 p.

Research output: Contribution to journalArticle

Toxicity Tests
Legislation
Cosmetics
Toxicology
Publications
2010

Alternatives to Conventional Toxicology Testing

Bressler, J., Bader, J. & Goldberg, A., Aug 12 2010, Toxicology Testing and Evaluation. Elsevier Inc., Vol. 3. p. 247-259 13 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Toxicology
Computer Simulation
Animal Testing Alternatives
Animal Rights
Animal Welfare

First alternative method validated by a retrospective weight-of-evidence approach to replace the Draize eye test for the identification of non-irritant substances for a defined applicability domain.

Hartung, T., Bruner, L., Curren, R., Eskes, C., Goldberg, A., McNamee, P., Scott, L. & Zuang, V., 2010, In : Altex. 27, 1, p. 43-51 9 p.

Research output: Contribution to journalArticle

Weights and Measures
Surface-Active Agents
Water
Validation Studies
Evidence-Based Medicine

New infectious diseases and industrial food animal production

Silbergeld, E., Davis, M., Feingold, B., Goldberg, A., Graham, J., Leibler, J., Peterson, A. & Price, L. B., 2010, In : Emerging Infectious Diseases. 16, 9, p. 1503 1 p.

Research output: Contribution to journalArticle

Disease Reservoirs
Animal Husbandry
Emerging Communicable Diseases
Food Contamination
Food Industry
2009

The role of an academic centre

Goldberg, A., Dec 2009, In : ATLA Alternatives to Laboratory Animals. 37, SUPPL. 2, p. 19-21 3 p.

Research output: Contribution to journalArticle

Education
Anniversaries and Special Events
Research
2008

Emerging new toxicology: An opportunity for contract research

Goldberg, A. & Hartung, T., Dec 2008, In : European Pharmaceutical Contractor. 49, p. 42-46 5 p.

Research output: Contribution to journalArticle

Contracts
Toxicology
Research
2007

Meeting report: Alternatives for developmental neurotoxicity testing

Lein, P., Locke, P. & Goldberg, A., May 2007, In : Environmental Health Perspectives. 115, 5, p. 764-768 5 p.

Research output: Contribution to journalArticle

Animal Testing Alternatives
Toxicology
Testing
United States Environmental Protection Agency
Animal Welfare

Meeting report: Hazard assessment for nanoparticles-report from an interdisciplinary workshop

Balbus, J. M., Maynard, A. D., Colvin, V. L., Castranova, V., Daston, G. P., Denison, R. A., Dreher, K. L., Goering, P. L., Goldberg, A., Kulinowski, K. M., Monteiro-Riviere, N. A., Oberdörster, G., Omenn, G. S., Pinkerton, K. E., Ramos, K. S., Rest, K. M., Sass, J. B., Silbergeld, E. & Wong, B. A., Nov 2007, In : Environmental Health Perspectives. 115, 11, p. 1654-1659 6 p.

Research output: Contribution to journalArticle

hazard assessment
Nanoparticles
Hazards
Education
Toxicity

Workgroup report: Incorporating In Vitro Alternative Methods for Developmental Neurotoxicity into International Hazard and Risk Assessment Strategies

Coecke, S., Goldberg, A., Allen, S., Buzanska, L., Calamandrei, G., Crofton, K., Hareng, L., Hartung, T., Knaut, H., Honegger, P., Jacobs, M., Lein, P., Li, A., Mundy, W., Owen, D., Schneider, S., Silbergeld, E., Reum, T., Trnovec, T., Monnet-Tschudi, F. & 1 others, Bal-Price, A., Jun 2007, In : Environmental Health Perspectives. 115, 6, p. 924-931 8 p.

Research output: Contribution to journalArticle

hazard assessment
Risk assessment
Hazards
risk assessment
Testing
2006

Alternatives in toxicology

Locke, P. & Goldberg, A., Jan 1 2006, Toxicology and Regulatory Process. CRC Press, p. 245-260 16 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Toxicology
Posters
History
Pharmacology
Pain

Protecting more than animals

Goldberg, A. & Hartung, T., Jan 2006, In : Scientific American. 294, 1, p. 84-91 8 p.

Research output: Contribution to journalArticle

Agrochemicals
Psychological Stress
Cell Culture Techniques
Safety

Report of an ISRTP Workshop: Progress and barriers to incorporating alternative toxicological methods in the U.S.

Becker, R. A., Borgert, C. J., Webb, S., Ansell, J., Amundson, S., Portier, C. J., Goldberg, A., Bruner, L. H., Rowan, A., Curren, R. D. & Stott, W. T., Oct 2006, In : Regulatory Toxicology and Pharmacology. 46, 1, p. 18-22 5 p.

Research output: Contribution to journalArticle

Toxicology
Education
Toxicity
Animals
Decision making
2005
Neurobiology
Testing
Nervous System
Mammals
Research
2004

Animals and alternatives: Societal expectations and scientific need

Goldberg, A., Dec 2004, In : ATLA Alternatives to Laboratory Animals. 32, 6, p. 545-551 7 p.

Research output: Contribution to journalArticle

animal experimentation
distress
pain
Animals
animals

Strategies to replace in vivo acute systemic toxicity testing: The report and recommendations of ECVAM workshop 50

Gennari, A., Van Den Berghe, C., Casati, S., Castell, J., Clemedson, C., Coecke, S., Colombo, A., Curren, R., Dal Negro, G., Goldberg, A., Gosmore, C., Hartung, T., Langezaal, I., Lessigiarska, I., Maas, W., Mangelsdorf, I., Parchment, R., Prieto, P., Sintes, J. R., Ryan, M. & 5 others, Schmuck, G., Stitzel, K., Stokes, W., Vericat, J. A. & Gribaldo, L., Oct 2004, In : ATLA Alternatives to Laboratory Animals. 32, 4, p. 437-459 23 p.

Research output: Contribution to journalArticle

Cosmetics
Cell death
Toxicity
Animals
Testing

TestSmart and toxic ignorance

Green, S. & Goldberg, A., 2004, In : ATLA Alternatives to Laboratory Animals. 32, SUPPL. 1A, p. 359-363 5 p.

Research output: Contribution to journalArticle

Endocrine Disruptors
Decision Trees
Poisons
toxicity
endocrine-disrupting chemicals
2003

Recognizing signs of pain [2] (multiple letters)

Karas, A. Z., Goldberg, A., Tranquilli, W. & Gross, D., Aug 1 2003, In : Journal of the American Veterinary Medical Association. 223, 3, p. 298-299 2 p.

Research output: Contribution to journalArticle

Drug Dose Response Relationship
Laboratory Animals
analgesics
Pain Measurement
normal values
2002

Alternatives: Refinement, reduction, and replacement of animal use in the life sciences

Goldberg, A. & Drnec, K., Jan 1 2002, Handbook of Laboratory Animal Science, Second Edition: Essential Principles and Practices. CRC Press, Vol. 1. p. 539-545 7 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

animal use replacement
animal use refinement
animal use reduction
Biological Science Disciplines
Animal Welfare

Use of animals in research: a science--society controversy? The American perspective: animal welfare issues.

Goldberg, A., 2002, In : Altex. 19, 3, p. 137-139 3 p.

Research output: Contribution to journalArticle

Animal Welfare
Birds
Japan
Public Sector
Laboratory Animals
2001

TestSmart-high production volume chemicals: An approach to implementing alternatives into regulatory toxicology

Green, S., Goldberg, A. & Zurlo, J., 2001, In : Toxicological Sciences. 63, 1, p. 6-14 9 p.

Research output: Contribution to journalArticle

Toxicology
Toxicity
Research
Screening
Assays

The TestSmart-HPV program - Development of an integrated approach for testing high production volume chemicals

Green, S., Goldberg, A. & Zurlo, J., Apr 2001, In : Regulatory Toxicology and Pharmacology. 33, 2, p. 105-109 5 p.

Research output: Contribution to journalArticle

Program Development
Screening
Testing
Animal Testing Alternatives
Animals
2000

The effects of pH and PEG 400-water cosolvents on oxytetracycline- magnesium complex formation and stability

Tongaree, S., Goldberg, A., Flanagan, D. R. & Poust, R. I., 2000, In : Pharmaceutical Development and Technology. 5, 2, p. 189-199 11 p.

Research output: Contribution to journalArticle

Oxytetracycline
Magnesium
Water
Circular Dichroism
High Pressure Liquid Chromatography
1999

The role of an academic center in promoting common goals

Zurlo, J. & Goldberg, A., 1999, In : Cambridge Quarterly of Healthcare Ethics. 8, 1, p. 58-63 6 p.

Research output: Contribution to journalArticle

Animal Testing Alternatives
Organizational Objectives
Animal Welfare
Federal Government
Laboratory Animals
1998

13th meeting of the Scientific Group on Methodologies for the Safety Evaluation of Chemicals (SGOMSEC): Validation and acute toxicity testing

Curren, R., Bruner, L., Goldberg, A. & Walum, E., 1998, In : Environmental Health Perspectives. 106, SUPPL. 2, p. 419-425 7 p.

Research output: Contribution to journalArticle

Chemical Safety
Group Processes
Toxicity
Poisons
safety

Cell-substratum interactions as a predictor of cytotoxicity

Keese, C. R., Karra, N., Dillon, B., Goldberg, A. & Giaever, I., Jun 1998, In : In Vitro and Molecular Toxicology: Journal of Basic and Applied Research. 11, 2, p. 183-192 10 p.

Research output: Contribution to journalArticle

Electric batteries
Cytotoxicity
Electric Impedance
Cell Communication
Detergents

Dermal toxicity: Alternative methods for risk assessment

Goldberg, A. & Maibach, H. I., 1998, In : Environmental Health Perspectives. 106, SUPPL. 2, p. 493-496 4 p.

Research output: Contribution to journalArticle

Dermatitis
Irritant Dermatitis
Risk assessment
Toxicity
Allergic Contact Dermatitis
1997

Confronting animal research issues

Zurlo, J. & Goldberg, A., May 26 1997, In : Scientist. 11, 11

Research output: Contribution to journalArticle

1996

Public support for research depends on humane treatment of lab animals

Zurlo, J., Goldberg, A. & Rudacille, D., Jul 22 1996, In : Scientist. 10, 15

Research output: Contribution to journalArticle

Seeking alternatives to whole-animal tests

Zurlo, J. & Goldberg, A., Mar 1996, In : Forum for Applied Research and Public Policy. 11, 1, p. 31-34 4 p.

Research output: Contribution to journalArticle

Animals

The three Rs: The way forward

Zurlo, J., Rodacille, D. & Goldberg, A., 1996, In : Environmental Health Perspectives. 104, 8, p. 878-880 3 p.

Research output: Contribution to journalArticle

The three Rs and biomedical research

Goldberg, A., Zurlo, J. & Rudacille, D., 1996, In : Science. 272, 5267, p. 1403 1 p.

Research output: Contribution to journalArticle

Animal Testing Alternatives
Animal Welfare
Laboratory Animals
Psychological Stress
Biomedical Research
1995

A modular approach to validation: A work in progress

Goldberg, A., Epstein, L. D. & Zurlo, J., 1995, In : In Vitro Toxicology: Journal of Molecular and Cellular Toxicology. 8, 4, p. 431-435 5 p.

Research output: Contribution to journalArticle

Assays
In Vitro Techniques
Validation Studies
Animals

Development of alternative methods

Goldberg, A., 1995, In : Journal of Toxicological Sciences. 20, 4, p. 443-449 7 p.

Research output: Contribution to journalArticle

Risk assessment
Toxicology
Safety
In Vitro Techniques

Responsible animal research: a riff of Rs.

Rowan, A. & Goldberg, A., May 1995, In : ATLA Alternatives to Laboratory Animals. 23, 3, p. 306-311 6 p.

Research output: Contribution to journalArticle

Animal Testing Alternatives
animal use alternatives
Moral Obligations
Animal Care Committees
social responsibility

The three Rs: the way forward: the report and recommendations of ECVAM Workshop 11.

Balls, M., Goldberg, A., Fentem, J. H., Broadhead, C. L., Burch, R. L., Festing, M. F. W., Frazier, J. M., Hendriksen, C. F. M., Jennings, M., van der Kamp, M. D. O., Morton, D. B., Rowan, A. N., Russell, C., Russell, W. M. S., Spielmann, H., Stephens, M. L., Stokes, W. S., Straughan, D. W., Yager, J. D., Zurlo, J. & 1 others, van Zutphen, B. F. M., Nov 1995, In : ATLA Alternatives to Laboratory Animals. 23, 6, p. 838-866 29 p.

Research output: Contribution to journalArticle

animal use alternatives
information dissemination
Institutional Animal Care and Use Committee
information services
international cooperation
1993

Framework for validation and implementation of in vitro toxicity tests

Goldberg, A., Frazier, J. M., Brusick, D., Dickens, M. S., Flint, O., Gettings, S. D., Hill, R. N., Lipnick, R. L., Renskers, K. J., Bradlaw, J. A., Scala, R. A., Veronesi, B., Green, S., Wilcox, N. L. & Curren, R. D., 1993, In : In Vitro Cellular and Developmental Biology - Animal. 29, 9, p. 688-692 5 p.

Research output: Contribution to journalArticle

Toxicity Tests
Toxicity
Animals
Tissue Banks
Acceptance tests

Framework for validation and implementation of in vitro toxicity tests: Report of the Validation and Technology Transfer Committee of the Johns Hopkins Center for Alternatives to Animal Testing

Goldberg, A., Frazier, J. M., Brusick, D., Dickens, M. S., Flint, O., Gettings, S. D., Hill, R. N., Lipnick, R. L., Renskers, K. J., Bradlaw, J. A., Scala, R. A., Veronesi, B., Green, S., Wilcox, N. L. & Curren, R. D., 1993, In : In Vitro Toxicology: Journal of Molecular and Cellular Toxicology. 6, 1, p. 47-55 9 p.

Research output: Contribution to journalArticle

Animal Testing Alternatives
Technology Transfer
Toxicity Tests
Technology transfer
Toxicity