Akira Sawa

2024

A whole-brain neuromark resting-state fMRI analysis of first-episode and early psychosis: Evidence of aberrant cortical-subcortical-cerebellar functional circuitry

Jensen, K. M., Calhoun, V. D., Fu, Z., Yang, K., Faria, A. V., Ishizuka, K., Sawa, A., Andrés-Camazón, P., Coffman, B. A., Seebold, D., Turner, J. A., Salisbury, D. F. & Iraji, A., Jan 2024, In: NeuroImage: Clinical. 41, 103584.

Research output: Contribution to journal › Article › peer-review

Open Access

Inflammation-related pathology in the olfactory epithelium: its impact on the olfactory system in psychotic disorders

Yang, K., Hasegawa, Y., Bhattarai, J. P., Hua, J., Dower, M., Etyemez, S., Prasad, N., Duvall, L., Paez, A., Smith, A., Wang, Y., Zhang, Y. F., Lane, A. P., Ishizuka, K., Kamath, V., Ma, M., Kamiya, A. & Sawa, A., 2024, (Accepted/In press) In: Molecular psychiatry.

Research output: Contribution to journal › Article › peer-review

Longitudinal trajectories of anterior cingulate glutamate and subclinical psychotic experiences in early adolescence: the impact of bullying victimization

Okada, N., Yahata, N., Koshiyama, D., Morita, K., Sawada, K., Kanata, S., Fujikawa, S., Sugimoto, N., Toriyama, R., Masaoka, M., Koike, S., Araki, T., Kano, Y., Endo, K., Yamasaki, S., Ando, S., Nishida, A., Hiraiwa-Hasegawa, M., Edden, R. A. E., Sawa, A., & 1 othersKasai, K., 2024, (Accepted/In press) In: Molecular psychiatry.

Research output: Contribution to journal › Article › peer-review

Open Access

Reduction of N-acetyl aspartate (NAA) in association with relapse in early-stage psychosis: a 7-Tesla MRS study

Mihaljevic, M., Chang, Y. H., Witmer, A. M., Coughlin, J. M., Schretlen, D. J., Barker, P. B., Yang, K. & Sawa, A., Dec 2024, In: Schizophrenia. 10, 1, 29.

Research output: Contribution to journal › Article › peer-review

Open Access

2023

Anterior Insula-Associated Social Novelty Recognition: Pivotal Roles of a Local Retinoic Acid Cascade and Oxytocin Signaling

Kim, S. H., An, K., Namkung, H., Saito, A., Rannals, M. D., Moore, J. R., Mihaljevic, M., Saha, S., Oh, S., Kondo, M. A., Ishizuka, K., Yang, K., Maher, B. J., Niwa, M. & Sawa, A., Apr 1 2023, In: The American journal of psychiatry. 180, 4, p. 305-317 13 p.

Research output: Contribution to journal › Article › peer-review

Apoptotic cell death in disease—Current understanding of the NCCD 2023

Vitale, I., Pietrocola, F., Guilbaud, E., Aaronson, S. A., Abrams, J. M., Adam, D., Agostini, M., Agostinis, P., Alnemri, E. S., Altucci, L., Amelio, I., Andrews, D. W., Aqeilan, R. I., Arama, E., Baehrecke, E. H., Balachandran, S., Bano, D., Barlev, N. A., Bartek, J., Bazan, N. G., & 208 othersBecker, C., Bernassola, F., Bertrand, M. J. M., Bianchi, M. E., Blagosklonny, M. V., Blander, J. M., Blandino, G., Blomgren, K., Borner, C., Bortner, C. D., Bove, P., Boya, P., Brenner, C., Broz, P., Brunner, T., Damgaard, R. B., Calin, G. A., Campanella, M., Candi, E., Carbone, M., Carmona-Gutierrez, D., Cecconi, F., Chan, F. K. M., Chen, G. Q., Chen, Q., Chen, Y. H., Cheng, E. H., Chipuk, J. E., Cidlowski, J. A., Ciechanover, A., Ciliberto, G., Conrad, M., Cubillos-Ruiz, J. R., Czabotar, P. E., D’Angiolella, V., Daugaard, M., Dawson, T. M., Dawson, V. L., De Maria, R., De Strooper, B., Debatin, K. M., Deberardinis, R. J., Degterev, A., Del Sal, G., Deshmukh, M., Di Virgilio, F., Diederich, M., Dixon, S. J., Dynlacht, B. D., El-Deiry, W. S., Elrod, J. W., Engeland, K., Fimia, G. M., Galassi, C., Ganini, C., Garcia-Saez, A. J., Garg, A. D., Garrido, C., Gavathiotis, E., Gerlic, M., Ghosh, S., Green, D. R., Greene, L. A., Gronemeyer, H., Häcker, G., Hajnóczky, G., Hardwick, J. M., Haupt, Y., He, S., Heery, D. M., Hengartner, M. O., Hetz, C., Hildeman, D. A., Ichijo, H., Inoue, S., Jäättelä, M., Janic, A., Joseph, B., Jost, P. J., Kanneganti, T. D., Karin, M., Kashkar, H., Kaufmann, T., Kelly, G. L., Kepp, O., Kimchi, A., Kitsis, R. N., Klionsky, D. J., Kluck, R., Krysko, D. V., Kulms, D., Kumar, S., Lavandero, S., Lavrik, I. N., Lemasters, J. J., Liccardi, G., Linkermann, A., Lipton, S. A., Lockshin, R. A., López-Otín, C., Luedde, T., MacFarlane, M., Madeo, F., Malorni, W., Manic, G., Mantovani, R., Marchi, S., Marine, J. C., Martin, S. J., Martinou, J. C., Mastroberardino, P. G., Medema, J. P., Mehlen, P., Meier, P., Melino, G., Melino, S., Miao, E. A., Moll, U. M., Muñoz-Pinedo, C., Murphy, D. J., Niklison-Chirou, M. V., Novelli, F., Núñez, G., Oberst, A., Ofengeim, D., Opferman, J. T., Oren, M., Pagano, M., Panaretakis, T., Pasparakis, M., Penninger, J. M., Pentimalli, F., Pereira, D. M., Pervaiz, S., Peter, M. E., Pinton, P., Porta, G., Prehn, J. H. M., Puthalakath, H., Rabinovich, G. A., Rajalingam, K., Ravichandran, K. S., Rehm, M., Ricci, J. E., Rizzuto, R., Robinson, N., Rodrigues, C. M. P., Rotblat, B., Rothlin, C. V., Rubinsztein, D. C., Rudel, T., Rufini, A., Ryan, K. M., Sarosiek, K. A., Sawa, A., Sayan, E., Schroder, K., Scorrano, L., Sesti, F., Shao, F., Shi, Y., Sica, G. S., Silke, J., Simon, H. U., Sistigu, A., Stephanou, A., Stockwell, B. R., Strapazzon, F., Strasser, A., Sun, L., Sun, E., Sun, Q., Szabadkai, G., Tait, S. W. G., Tang, D., Tavernarakis, N., Troy, C. M., Turk, B., Urbano, N., Vandenabeele, P., Vanden Berghe, T., Vander Heiden, M. G., Vanderluit, J. L., Verkhratsky, A., Villunger, A., von Karstedt, S., Voss, A. K., Vousden, K. H., Vucic, D., Vuri, D., Wagner, E. F., Walczak, H., Wallach, D., Wang, R., Wang, Y., Weber, A., Wood, W., Yamazaki, T., Yang, H. T., Zakeri, Z., Zawacka-Pankau, J. E., Zhang, L., Zhang, H., Zhivotovsky, B., Zhou, W., Piacentini, M., Kroemer, G. & Galluzzi, L., May 2023, In: Cell death and differentiation. 30, 5, p. 1097-1154 58 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

Brain regions associated with olfactory dysfunction in first episode psychosis patients

Etyemez, S., Narita, Z., Mihaljevic, M., Coughlin, J. M., Nestadt, G., Nucifora, F. C. J., Sedlak, T. W., Cascella, N. G., Batt, F. D., Hua, J., Faria, A., Ishizuka, K., Kamath, V., Yang, K. & Sawa, A., 2023, In: World Journal of Biological Psychiatry. 24, 2, p. 178-186 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Cortical morphology in patients with the deficit and non-deficit syndrome of schizophrenia: a worldwide meta- and mega-analyses

Banaj, N., Vecchio, D., Piras, F., De Rossi, P., Bustillo, J., Ciufolini, S., Dazzan, P., Di Forti, M., Dickie, E. W., Ford, J. M., Fuentes-Claramonte, P., Gruber, O., Guerrero-Pedraza, A., Hamilton, H. K., Howells, F. M., Kraemer, B., Lawrie, S. M., Mathalon, D. H., Murray, R., Pomarol-Clotet, E., & 22 othersPotkin, S. G., Preda, A., Radua, J., Richter, A., Salvador, R., Sawa, A., Scheffler, F., Sim, K., Spaniel, F., Stein, D. J., Temmingh, H. S., Thomopoulos, S. I., Tomecek, D., Uhlmann, A., Voineskos, A., Yang, K., Jahanshad, N., Thompson, P. M., Van Erp, T. G. M., Turner, J. A., Spalletta, G. & Piras, F., Oct 2023, In: Molecular psychiatry. 28, 10, p. 4363-4373 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Identifying canonical and replicable multi-scale intrinsic connectivity networks in 100k+ resting-state fMRI datasets

Iraji, A., Fu, Z., Faghiri, A., Duda, M., Chen, J., Rachakonda, S., DeRamus, T., Kochunov, P., Adhikari, B. M., Belger, A., Ford, J. M., Mathalon, D. H., Pearlson, G. D., Potkin, S. G., Preda, A., Turner, J. A., van Erp, T. G. M., Bustillo, J. R., Yang, K., Ishizuka, K., & 17 othersFaria, A., Sawa, A., Hutchison, K., Osuch, E. A., Theberge, J., Abbott, C., Mueller, B. A., Zhi, D., Zhuo, C., Liu, S., Xu, Y., Salman, M., Liu, J., Du, Y., Sui, J., Adali, T. & Calhoun, V. D., Dec 1 2023, In: Human Brain Mapping. 44, 17, p. 5729-5748 20 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Longitudinal changes in brain metabolites in healthy controls and patients with first episode psychosis: a 7-Tesla MRS study

Wang, M., Barker, P. B., Cascella, N. G., Coughlin, J. M., Nestadt, G., Nucifora, F. C., Sedlak, T. W., Kelly, A., Younes, L., Geman, D., Palaniyappan, L., Sawa, A. & Yang, K., May 2023, In: Molecular psychiatry. 28, 5, p. 2018-2029 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Microglial cannabinoid receptor type 1 mediates social memory deficits in mice produced by adolescent THC exposure and 16p11.2 duplication

Hasegawa, Y., Kim, J., Ursini, G., Jouroukhin, Y., Zhu, X., Miyahara, Y., Xiong, F., Madireddy, S., Obayashi, M., Lutz, B., Sawa, A., Brown, S. P., Pletnikov, M. V. & Kamiya, A., Dec 2023, In: Nature communications. 14, 1, 6559.

Research output: Contribution to journal › Article › peer-review

Open Access

Postsurgical morbidity and mortality favorably informs deep brain stimulation for new indications including schizophrenia and schizoaffective disorder

Gault, J. M., Hosokawa, P., Kramer, D., Saks, E. R., Appelbaum, P. S., Thompson, J. A., Olincy, A., Cascella, N., Sawa, A., Goodman, W., Moukaddam, N., Sheth, S. A., Anderson, W. S. & Davis, R. A., 2023, In: Frontiers in Surgery. 10, 958452.

Research output: Contribution to journal › Article › peer-review

Open Access

Relation between white matter integrity, perfusion, and processing speed in early-stage schizophrenia

Chen, F., Mihaljevic, M., Hou, Z., Li, Y., Lu, H., Mori, S., Sawa, A. & Faria, A. V., Jul 2023, In: Journal of Psychiatric Research. 163, p. 166-171 6 p.

Research output: Contribution to journal › Article › peer-review

The miR-124-AMPAR pathway connects polygenic risks with behavioral changes shared between schizophrenia and bipolar disorder

Namkung, H., Yukitake, H., Fukudome, D., Lee, B. J., Tian, M., Ursini, G., Saito, A., Lam, S., Kannan, S., Srivastava, R., Niwa, M., Sharma, K., Zandi, P., Jaaro-Peled, H., Ishizuka, K., Chatterjee, N., Huganir, R. L. & Sawa, A., Jan 18 2023, In: Neuron. 111, 2, p. 220-235.e9

Research output: Contribution to journal › Article › peer-review

Open Access

Towards a youth mental health paradigm: a perspective and roadmap

Uhlhaas, P. J., Davey, C. G., Mehta, U. M., Shah, J., Torous, J., Allen, N. B., Avenevoli, S., Bella-Awusah, T., Chanen, A., Chen, E. Y. H., Correll, C. U., Do, K. Q., Fisher, H. L., Frangou, S., Hickie, I. B., Keshavan, M. S., Konrad, K., Lee, F. S., Liu, C. H., Luna, B., & 17 othersMcGorry, P. D., Meyer-Lindenberg, A., Nordentoft, M., Öngür, D., Patton, G. C., Paus, T., Reininghaus, U., Sawa, A., Schoenbaum, M., Schumann, G., Srihari, V. H., Susser, E., Verma, S. K., Woo, T. W., Yang, L. H., Yung, A. R. & Wood, S. J., Aug 2023, In: Molecular psychiatry. 28, 8, p. 3171-3181 11 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

Using brain cell-type-specific protein interactomes to interpret neurodevelopmental genetic signals in schizophrenia

Schizophrenia Working Group of the Psychiatric Genomics Consortium, Stanley Global Asia Initiatives, Psychosis Endophenotypes International Consortium & Wellcome Trust Case Control Consortium, May 19 2023, In: iScience. 26, 5, 106701.

Research output: Contribution to journal › Article › peer-review

Open Access

Variability and magnitude of brain glutamate levels in schizophrenia: a meta and mega-analysis

Merritt, K., McCutcheon, R. A., Aleman, A., Ashley, S., Beck, K., Block, W., Bloemen, O. J. N., Borgan, F., Boules, C., Bustillo, J. R., Capizzano, A. A., Coughlin, J. M., David, A., de la Fuente-Sandoval, C., Demjaha, A., Dempster, K., Do, K. Q., Du, F., Falkai, P., Galińska-Skok, B., & 58 othersGallinat, J., Gasparovic, C., Ginestet, C. E., Goto, N., Graff-Guerrero, A., Ho, B. C., Howes, O., Jauhar, S., Jeon, P., Kato, T., Kaufmann, C. A., Kegeles, L. S., Keshavan, M. S., Kim, S. Y., King, B., Kunugi, H., Lauriello, J., León-Ortiz, P., Liemburg, E., Mcilwain, M. E., Modinos, G., Mouchlianitis, E., Nakamura, J., Nenadic, I., Öngür, D., Ota, M., Palaniyappan, L., Pantelis, C., Patel, T., Plitman, E., Posporelis, S., Purdon, S. E., Reichenbach, J. R., Renshaw, P. F., Reyes-Madrigal, F., Russell, B. R., Sawa, A., Schaefer, M., Shungu, D. C., Smesny, S., Stanley, J. A., Stone, J., Szulc, A., Taylor, R., Thakkar, K. N., Théberge, J., Tibbo, P. G., van Amelsvoort, T., Walecki, J., Williamson, P. C., Wood, S. J., Xin, L., Yamasue, H., McGuire, P., Egerton, A., de la Fuente-Sandoval, C., van Amelsvoort, T. & McGuire, P. K., May 2023, In: Molecular psychiatry. 28, 5, p. 2039-2048 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2022

A comparative neuroimaging perspective of olfaction and higher-order olfactory processing: on health and disease

Kulason, S., Ratnanather, J. T., Miller, M. I., Kamath, V., Hua, J., Yang, K., Ma, M., Ishizuka, K. & Sawa, A., Sep 2022, In: Seminars in Cell and Developmental Biology. 129, p. 22-30 9 p.

Research output: Contribution to journal › Review article › peer-review

A multimodal study of a first episode psychosis cohort: potential markers of antipsychotic treatment resistance

Yang, K., Longo, L., Narita, Z., Cascella, N., Nucifora, F. C., Coughlin, J. M., Nestadt, G., Sedlak, T. W., Mihaljevic, M., Wang, M., Kenkare, A., Nagpal, A., Sethi, M., Kelly, A., Di Carlo, P., Kamath, V., Faria, A., Barker, P. & Sawa, A., Feb 2022, In: Molecular psychiatry. 27, 2, p. 1184-1191 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

A Perspective on the Potential Involvement of Impaired Proteostasis in Neuropsychiatric Disorders

Hui, K. K., Endo, R., Sawa, A. & Tanaka, M., Feb 15 2022, In: Biological psychiatry. 91, 4, p. 335-345 11 p.

Research output: Contribution to journal › Review article › peer-review

Author Correction: Improving polygenic prediction in ancestrally diverse populations (Nature Genetics, (2022), 54, 5, (573-580), 10.1038/s41588-022-01054-7)

Stanley Global Asia Initiatives, Aug 2022, In: Nature genetics. 54, 8, p. 1259 1 p.

Research output: Contribution to journal › Comment/debate › peer-review

Open Access

Dysfunction of mitochondria and GABAergic interneurons in the anterior cingulate cortex of individuals with schizophrenia

Kondo, M. A., Norris, A. L., Yang, K., Cheshire, M., Newkirk, I., Chen, X., Ishizuka, K., Jaffe, A. E., Sawa, A. & Pevsner, J., Dec 2022, In: Neuroscience Research. 185, p. 67-72 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Editorial: Immune Associated Mental Illnesses in Adolescents and Young Adults: Pathophysiological Role and Therapeutic Perspectives

Banati, R. B., Rohleder, C., Leweke, F. M., Mueller, N., Sawa, A., Yolken, R. H. & Hickie, I. B., Mar 14 2022, In: Frontiers in Psychiatry. 13, 871719.

Research output: Contribution to journal › Editorial › peer-review

Open Access

Going from lines to triangles: A formulation for time-frequency moments of time-series with application to study fMRI

Faghiri, A., Iraji, A., Lewis, N., Yang, K., Ishizuka, K., Sawa, A., Adali, T. & Calhoun, V., 2022, IVMSP 2022 - 2022 IEEE 14th Image, Video, and Multidimensional Signal Processing Workshop. Institute of Electrical and Electronics Engineers Inc., (IVMSP 2022 - 2022 IEEE 14th Image, Video, and Multidimensional Signal Processing Workshop).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Improving polygenic prediction in ancestrally diverse populations

Stanley Global Asia Initiatives, May 2022, In: Nature genetics. 54, 5, p. 573-580 8 p.

Research output: Contribution to journal › Article › peer-review

Molecular dissection of cognition, emotion and thoughts

Sakurai, T. & Sawa, A., Sep 2022, In: Seminars in Cell and Developmental Biology. 129, p. 1-2 2 p.

Research output: Contribution to journal › Editorial › peer-review

Olfactory dysfunction and face processing of social cognition in first-episode psychosis

Etyemez, S., Narita, Z., Mihaljevic, M., Ishizuka, K., Kamath, V., Yang, K. & Sawa, A., Mar 2022, In: Neuroscience Research. 176, p. 79-84 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Olfactory impairment in psychiatric disorders: Does nasal inflammation impact disease psychophysiology?

Hasegawa, Y., Ma, M., Sawa, A., Lane, A. P. & Kamiya, A., Dec 2022, In: Translational psychiatry. 12, 1, 314.

Research output: Contribution to journal › Review article › peer-review

Open Access

Olfactory modulation of the medial prefrontal cortex circuitry: Implications for social cognition

Bhattarai, J. P., Etyemez, S., Jaaro-Peled, H., Janke, E., Leon Tolosa, U. D., Kamiya, A., Gottfried, J. A., Sawa, A. & Ma, M., Sep 2022, In: Seminars in Cell and Developmental Biology. 129, p. 31-39 9 p.

Research output: Contribution to journal › Review article › peer-review

Olfactory neuronal cells as a promising tool to realize the “druggable genome” approach for drug discovery in neuropsychiatric disorders

Mihaljevic, M., Lam, M., Ayala-Grosso, C., Davis-Batt, F., Schretlen, D. J., Ishizuka, K., Yang, K. & Sawa, A., 2022, In: Frontiers in Neuroscience. 16, 1081124.

Research output: Contribution to journal › Article › peer-review

Open Access

Paradigm shift on the concept of schizophrenia that matches with both academic and clinical needs

Sawa, A., Yang, K. & Cascella, N. G., Apr 2022, In: Schizophrenia Research. 242, p. 123-125 3 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Parsing neural circuits of fear learning and extinction across basic and clinical neuroscience: Towards better translation

Namkung, H., Thomas, K. L., Hall, J. & Sawa, A., Mar 2022, In: Neuroscience and Biobehavioral Reviews. 134, 104502.

Research output: Contribution to journal › Review article › peer-review

Open Access

Prenatal immune stress blunts microglia reactivity, impairing neurocircuitry

Hayes, L. N., An, K., Carloni, E., Li, F., Vincent, E., Trippaers, C., Paranjpe, M., Dölen, G., Goff, L. A., Ramos, A., Kano, S. I. & Sawa, A., Oct 13 2022, In: Nature. 610, 7931, p. 327-334 8 p.

Research output: Contribution to journal › Article › peer-review

Regulation of sensorimotor gating via Disc1/Huntingtin-mediated Bdnf transport in the cortico-striatal circuit

Jaaro-Peled, H., Kumar, S., Hughes, D., Sumitomo, A., Kim, S. H., Zoubovsky, S., Hirota-Tsuyada, Y., Zala, D., Bruyere, J., Katz, B. M., Huang, B., Flores, R., Narayan, S., Hou, Z., Economides, A. N., Hikida, T., Wetsel, W. C., Deisseroth, K., Mori, S., Brandon, N. J., & 7 othersTanaka, M., Ishizuka, K., Houslay, M. D., Saudou, F., Dzirasa, K., Sawa, A. & Tomoda, T., Mar 2022, In: Molecular psychiatry. 27, 3, p. 1805-1815 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Sex-specific involvement of the Notch–JAG pathway in social recognition

Jaaro-Peled, H., Landek-Salgado, M. A., Cascella, N. G., Nucifora, F. C., Coughlin, J. M., Nestadt, G., Sedlak, T. W., Lavoie, J., De Silva, S., Lee, S., Tajinda, K., Hiyama, H., Ishizuka, K., Yang, K. & Sawa, A., Dec 2022, In: Translational psychiatry. 12, 1, 99.

Research output: Contribution to journal › Article › peer-review

Open Access

Tagging active neurons by soma-targeted Cal-Light

Hyun, J. H., Nagahama, K., Namkung, H., Mignocchi, N., Roh, S. E., Hannan, P., Krüssel, S., Kwak, C., McElroy, A., Liu, B., Cui, M., Lee, S., Lee, D., Huganir, R. L., Worley, P. F., Sawa, A. & Kwon, H. B., Dec 2022, In: Nature communications. 13, 1, 7692.

Research output: Contribution to journal › Article › peer-review

Open Access

Virtual Ontogeny of Cortical Growth Preceding Mental Illness

Patel, Y., Shin, J., Abé, C., Agartz, I., Alloza, C., Alnæs, D., Ambrogi, S., Antonucci, L. A., Arango, C., Arolt, V., Auzias, G., Ayesa-Arriola, R., Banaj, N., Banaschewski, T., Bandeira, C., Başgöze, Z., Cupertino, R. B., Bau, C. H. D., Bauer, J., Baumeister, S., & 176 othersBernardoni, F., Bertolino, A., Bonnin, C. D. M., Brandeis, D., Brem, S., Bruggemann, J., Bülow, R., Bustillo, J. R., Calderoni, S., Calvo, R., Canales-Rodríguez, E. J., Cannon, D. M., Carmona, S., Carr, V. J., Catts, S. V., Chenji, S., Chew, Q. H., Coghill, D., Connolly, C. G., Conzelmann, A., Craven, A. R., Crespo-Facorro, B., Cullen, K., Dahl, A., Dannlowski, U., Davey, C. G., Deruelle, C., Díaz-Caneja, C. M., Dohm, K., Ehrlich, S., Epstein, J., Erwin-Grabner, T., Eyler, L. T., Fedor, J., Fitzgerald, J., Foran, W., Ford, J. M., Fortea, L., Fuentes-Claramonte, P., Fullerton, J., Furlong, L., Gallagher, L., Gao, B., Gao, S., Goikolea, J. M., Gotlib, I., Goya-Maldonado, R., Grabe, H. J., Green, M., Grevet, E. H., Groenewold, N. A., Grotegerd, D., Gruber, O., Haavik, J., Hahn, T., Harrison, B. J., Heindel, W., Henskens, F., Heslenfeld, D. J., Hilland, E., Hoekstra, P. J., Hohmann, S., Holz, N., Howells, F. M., Ipser, J. C., Jahanshad, N., Jakobi, B., Jansen, A., Janssen, J., Jonassen, R., Kaiser, A., Kaleda, V., Karantonis, J., King, J. A., Kircher, T., Kochunov, P., Koopowitz, S. M., Landén, M., Landrø, N. I., Lawrie, S., Lebedeva, I., Luna, B., Lundervold, A. J., MacMaster, F. P., Maglanoc, L. A., Mathalon, D. H., McDonald, C., McIntosh, A., Meinert, S., Michie, P. T., Mitchell, P., Moreno-Alcázar, A., Mowry, B., Muratori, F., Nabulsi, L., Nenadić, I., O'Gorman Tuura, R., Oosterlaan, J., Overs, B., Pantelis, C., Parellada, M., Pariente, J. C., Pauli, P., Pergola, G., Piarulli, F. M., Picon, F., Piras, F., Pomarol-Clotet, E., Pretus, C., Quidé, Y., Radua, J., Ramos-Quiroga, J. A., Rasser, P. E., Reif, A., Retico, A., Roberts, G., Rossell, S., Rovaris, D. L., Rubia, K., Sacchet, M., Salavert, J., Salvador, R., Sarró, S., Sawa, A., Schall, U., Scott, R., Selvaggi, P., Silk, T., Sim, K., Skoch, A., Spalletta, G., Spaniel, F., Stein, D. J., Steinsträter, O., Stolicyn, A., Takayanagi, Y., Tamm, L., Tavares, M., Teumer, A., Thiel, K., Thomopoulos, S. I., Tomecek, D., Tomyshev, A. S., Tordesillas-Gutiérrez, D., Tosetti, M., Uhlmann, A., Van Rheenen, T., Vazquez-Bourgón, J., Vernooij, M. W., Vieta, E., Vilarroya, O., Weickert, C., Weickert, T., Westlye, L. T., Whalley, H., Willinger, D., Winter, A., Wittfeld, K., Yang, T. T., Yoncheva, Y., Zijlmans, J. L., Hoogman, M., Franke, B., van Rooij, D., Buitelaar, J., Ching, C. R. K., Andreassen, O. A., Pozzi, E., Veltman, D., Schmaal, L., van Erp, T. G. M., Turner, J., Castellanos, F. X., Pausova, Z., Thompson, P. & Paus, T., Aug 15 2022, In: Biological psychiatry. 92, 4, p. 299-313 15 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2021

A biomarker-authenticated model of schizophrenia implicating NPTX2 loss of function

Xiao, M. F., Roh, S. E., Zhou, J., Chien, C. C., Lucey, B. P., Craig, M. T., Hayes, L. N., Coughlin, J. M., Markus Leweke, F., Jia, M., Xu, D., Zhou, W., Conover Talbot, J., Arnold, D. B., Staley, M., Jiang, C., Reti, I. M., Sawa, A., Pelkey, K. A., McBain, C. J., & 2 othersSavonenko, A. & Worley, P. F., Nov 2021, In: Science Advances. 7, 48, eabf6935.

Research output: Contribution to journal › Article › peer-review

Open Access

A lrrk2 gtp binding inhibitor, 68, reduces lps‐induced signaling events and tnf‐α release in human lymphoblasts

Li, T., Ning, B., Kong, L., Dai, B., He, X., Thomas, J. M., Sawa, A., Ross, C. A. & Smith, W. W., Feb 2021, In: Cells. 10, 2, p. 1-12 12 p., 480.

Research output: Contribution to journal › Article › peer-review

Open Access

A multimodal approach to studying the relationship between peripheral glutathione, brain glutamate, and cognition in health and in schizophrenia

Coughlin, J. M., Yang, K., Marsman, A., Pradhan, S., Wang, M., Ward, R. E., Bonekamp, S., Ambinder, E. B., Higgs, C. P., Kim, P. K., Edwards, J. A., Varvaris, M., Wang, H., Posporelis, S., Ma, S., Tsujimura, T., Edden, R. A. E., Pomper, M. G., Sedlak, T. W., Fournier, M., & 4 othersSchretlen, D. J., Cascella, N. G., Barker, P. B. & Sawa, A., Jul 2021, In: Molecular psychiatry. 26, 7, p. 3502-3511 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

3 Scopus citations

Association of Age, Antipsychotic Medication, and Symptom Severity in Schizophrenia with Proton Magnetic Resonance Spectroscopy Brain Glutamate Level: A Mega-analysis of Individual Participant-Level Data

Merritt, K., McGuire, P. K., Egerton, A., Aleman, A., Block, W., Bloemen, O. J. N., Borgan, F., Bustillo, J. R., Capizzano, A. A., Coughlin, J. M., De La Fuente-Sandoval, C., Demjaha, A., Dempster, K., Do, K. Q., Du, F., Falkai, P., Galinska-Skok, B., Gallinat, J., Gasparovic, C., Ginestet, C. E., & 46 othersGoto, N., Graff-Guerrero, A., Ho, B. C., Howes, O. D., Jauhar, S., Jeon, P., Kato, T., Kaufmann, C. A., Kegeles, L. S., Keshavan, M., Kim, S. Y., Kunugi, H., Lauriello, J., Liemburg, E. J., McIlwain, M. E., Modinos, G., Mouchlianitis, E. D., Nakamura, J., Nenadic, I., Öngür, D., Ota, M., Palaniyappan, L., Pantelis, C., Plitman, E., Posporelis, S., Purdon, S. E., Reichenbach, J. R., Renshaw, P. F., Russell, B. R., Sawa, A., Schaefer, M., Shungu, D. C., Smesny, S., Stanley, J. A., Stone, J. M., Szulc, A., Taylor, R., Thakkar, K., Théberge, J., Tibbo, P. G., Van Amelsvoort, T., Walecki, J., Williamson, P. C., Wood, S. J., Xin, L. & Yamasue, H., Jun 2021, In: JAMA psychiatry. 78, 6, p. 667-681 15 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Better functional capacity and cognitive performance in clozapine responders compared to non-responders: A cross-sectional study

Nucifora, F. C., Baker, K. K., Stricklin, A., Cuerdo, A., Parke, K. R., DuBois, S., Nucifora, L. G., Margolis, R. L., Sawa, A. & Harvey, P. D., Mar 2021, In: Schizophrenia Research. 229, p. 134-136 3 p.

Research output: Contribution to journal › Letter › peer-review

Causal impact of local inflammation in the nasal cavity on higher brain function and cognition

Hasegawa, Y., Namkung, H., Smith, A., Sakamoto, S., Zhu, X., Ishizuka, K., Lane, A. P., Sawa, A. & Kamiya, A., Nov 2021, In: Neuroscience Research. 172, p. 110-115 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Characterization of antipsychotic medications, amino acid signatures, and platelet-activating factor in first-episode psychosis

Avigdor, B. E., Yang, K., Shinder, I., Orsburn, B. C., Rais, R., Kano, S. I., Sawa, A. & Pevsner, J., Dec 2021, In: Biomarkers in Neuropsychiatry. 5, 100045.

Research output: Contribution to journal › Article › peer-review

Open Access

Deep Brain Stimulation of the Substantia Nigra Pars Reticulata for Treatment-Resistant Schizophrenia: A Case Report

Cascella, N., Butala, A. A., Mills, K., Kim, M. J., Salimpour, Y., Wojtasievicz, T., Hwang, B., Cullen, B., Figee, M., Moran, L., Lenz, F., Sawa, A., Schretlen, D. J. & Anderson, W., Nov 15 2021, In: Biological psychiatry. 90, 10, p. e57-e59

Research output: Contribution to journal › Letter › peer-review

Elevated body fat increases amphetamine accumulation in brain: evidence from genetic and diet-induced forms of adiposity

Fu, X., Shah, A. P., Keighron, J., Mou, T. C. M., Ladenheim, B., Alt, J., Fukudome, D., Niwa, M., Tamashiro, K. L., Tanda, G., Sawa, A., Cadet, J. L., Rais, R. & Baraban, J. M., Dec 2021, In: Translational psychiatry. 11, 1, 427.

Research output: Contribution to journal › Article › peer-review

Open Access

Endoscopy and Barrett’s esophagus: Current perspectives in the US and Japan

Oda, M., Kalloo, A., Mizukami, K., Murakami, K. & Sawa, A., Feb 1 2021, In: Internal Medicine. 60, 3, p. 327-335 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Face processing of social cognition in patients with first episode psychosis: Its deficits and association with the right subcallosal anterior cingulate cortex

Narita, Z., Yang, K., Kuga, H., Piancharoen, P., Etyemez, S., Faria, A., Mihaljevic, M., Longo, L., Namkung, H., Coughlin, J. M., Nestadt, G., Nucifora, F. C., Sedlak, T. W., Schaub, R., Crawford, J., Schretlen, D. J., Miyata, J., Ishizuka, K. & Sawa, A., Dec 2021, In: Schizophrenia Research. 238, p. 99-107 9 p.

Research output: Contribution to journal › Article › peer-review

From population to neuron: exploring common mediators for metabolic problems and mental illnesses

Takayanagi, Y., Ishizuka, K., Laursen, T. M., Yukitake, H., Yang, K., Cascella, N. G., Ueda, S., Sumitomo, A., Narita, Z., Horiuchi, Y., Niwa, M., Taguchi, A., White, M. F., Eaton, W. W., Mortensen, P. B., Sakurai, T. & Sawa, A., Aug 2021, In: Molecular psychiatry. 26, 8, p. 3931-3942 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

Increased novelty-induced locomotion, sensitivity to amphetamine, and extracellular dopamine in striatum of Zdhhc15-deficient mice

Mejias, R., Rodriguez-Gotor, J. J., Niwa, M., Krasnova, I. N., Adamczyk, A., Han, M., Thomas, G. M., Xi, Z. X., Huganir, R. L., Pletnikov, M. V., Sawa, A., Cadet, J. L. & Wang, T., Jun 2021, In: Translational psychiatry. 11, 1, 65.

Research output: Contribution to journal › Article › peer-review

Open Access

Akira Sawa

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