Ahizechukwu Eke

Assistant Professor

20102019
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Research Output 2010 2019

2019
17-alpha-Hydroxyprogesterone
Glucose Intolerance
Meta-Analysis
Gestational Diabetes
Pregnancy

Cobicistat as a Pharmacoenhancer in Pregnancy and Postpartum: Progress to Date and Next Steps

Eke, A. & Mirochnick, M. H., Jun 1 2019, In : Journal of clinical pharmacology. 59, 6, p. 779-783 5 p.

Research output: Contribution to journalComment/debate

Ritonavir
Postpartum Period
Pregnancy
Cobicistat

Intrauterine cleaning after placental delivery at cesarean section: a randomized controlled trial

Eke, A., Drnec, S., Buras, A., Woo, J., Martin, D. & Roth, S., Jan 17 2019, In : Journal of Maternal-Fetal and Neonatal Medicine. 32, 2, p. 236-242 7 p.

Research output: Contribution to journalArticle

Cesarean Section
Randomized Controlled Trials
Endometritis
Intraoperative Complications
Patient Readmission

Oral or Vaginal Misoprostol for Labor Induction and Cesarean Delivery Risk

Handal-Orefice, R. C., Friedman, A. M., Chouinard, S. M., Eke, A., Feinberg, B., Politch, J., Iverson, R. E. & Yarrington, C. D., Jul 1 2019, In : Obstetrics and gynecology. 134, 1, p. 10-16 7 p.

Research output: Contribution to journalArticle

Induced Labor
Misoprostol
Odds Ratio
Cervical Ripening
Tertiary Healthcare

Palliative interventions for controlling vaginal bleeding in advanced cervical cancer

Eleje, G. U., Eke, A., Igberase, G. O., Igwegbe, A. O. & Eleje, L. I., Mar 19 2019, In : Cochrane Database of Systematic Reviews. 2019, 3, CD011000.

Research output: Contribution to journalReview article

Uterine Hemorrhage
Uterine Cervical Neoplasms
Radiotherapy
Interventional Radiology
Palliative Care

Performance indices of AmnioQuick Duo+ versus placental α-microglobulin-1 tests for women with prolonged premature rupture of membranes

Eleje, G. U., Ezugwu, E. C., Ezebialu, I. U., Ojiegbe, N. O., Egeonu, R. O., Obiora, C. C., Okafor, C. G., Ikechebelu, J. I. & Eke, A., Feb 1 2019, In : International Journal of Gynecology and Obstetrics. 144, 2, p. 180-186 7 p.

Research output: Contribution to journalArticle

Rupture
Membranes
Chorioamnionitis
Nigeria
France

Pharmacokinetics of Increased Nelfinavir Plasma Concentrations in Women During Pregnancy and Postpartum

IMPAACT P1026s Protocol Team, Mar 1 2019, In : Journal of clinical pharmacology. 59, 3, p. 386-393 8 p.

Research output: Contribution to journalArticle

Nelfinavir
Third Pregnancy Trimester
Postpartum Period
Pharmacokinetics
Pregnancy

Pharmacologic research in pregnant women — Time to get it right

Eke, A., Dooley, K. E. & Sheffield, J., Apr 4 2019, In : New England Journal of Medicine. 380, 14, p. 1293-1295 3 p.

Research output: Contribution to journalReview article

Live Birth
Pregnant Women
Research

Ritonavir and cobicistat as pharmacokinetic enhancers in pregnant women

Eke, A. & Mirochnick, M., Jul 3 2019, In : Expert Opinion on Drug Metabolism and Toxicology. 15, 7, p. 523-525 3 p.

Research output: Contribution to journalArticle

Ritonavir
Pharmacokinetics
Pregnant Women
Pregnancy
Cobicistat

Single versus Double-Balloon Transcervical Catheter for Labor Induction: A Systematic Review and Meta-Analysis

De Los Reyes, S. X., Sheffield, J. & Eke, A., Jan 1 2019, In : American journal of perinatology. 36, 8, p. 790-797 8 p.

Research output: Contribution to journalArticle

Induced Labor
Meta-Analysis
Catheters
Confidence Intervals
MEDLINE
2018
17-alpha-Hydroxyprogesterone
Premature Birth
Meta-Analysis
History
Necrotizing Enterocolitis
Meta-Analysis
Odds Ratio
Confidence Intervals
Pregnancy
Fetal Death

Connect the dots - February 2018

Eke, A., Link, H., Zertuche, A. D. & Chescheir, N. C., Feb 1 2018, In : Obstetrics and gynecology. 131, 2, p. 395-396 2 p.

Research output: Contribution to journalShort survey

Connect the Dots-November 2018

Sinning, K., Eke, A., Spellman, C. & Chescheir, N. C., Jan 1 2018, In : Obstetrics and gynecology. 132, 5, p. 1300-1301 2 p.

Research output: Contribution to journalComment/debate

Connect the Dots-October 2018

Arroyo Sánchez, G., Langhorne, O. J., Eke, A. C. & Chescheir, N. C., Oct 1 2018, In : Obstetrics and gynecology. 132, 4, p. 1059-1060 2 p.

Research output: Contribution to journalArticle

Connect the Dots-September 2018

Eke, A. C., Dixon, A. M., Heyrana, K. & Chescheir, N. C., Sep 1 2018, In : Obstetrics and gynecology. 132, 3, p. 775-776 2 p.

Research output: Contribution to journalArticle

Fruit and vegetable consumption and risk of endometriosis

Harris, H. R., Eke, A., Chavarro, J. E. & Missmer, S. A., Apr 1 2018, In : Human Reproduction. 33, 4, p. 715-727 13 p.

Research output: Contribution to journalArticle

Open Access
Endometriosis
Vegetables
Fruit
Citrus
Food

Rilpivirine plasma and cervicovaginal concentrations in women during pregnancy and postpartum

Eke, A., Chakhtoura, N., Kashuba, A., Best, B. M., Sykes, C., Wang, J., Stek, A. M., Smith, E., Calabrese, S., Capparelli, E. V. & Mirochnick, M., Jan 1 2018, In : Journal of Acquired Immune Deficiency Syndromes. 78, 3, p. 308-313 6 p.

Research output: Contribution to journalArticle

Rilpivirine
Postpartum Period
Pregnancy
Third Pregnancy Trimester
Clinical Protocols
Brain Hypoxia-Ischemia
Chorioamnionitis
Parity
Morbidity
Odds Ratio

Risk-reducing bilateral salpingo-oophorectomy in women with BRCA1 or BRCA2 mutations

Eleje, G. U., Eke, A., Ezebialu, I. U., Ikechebelu, J. I., Ugwu, E. O. & Okonkwo, O. O., Aug 24 2018, In : The Cochrane database of systematic reviews. 8, p. CD012464

Research output: Contribution to journalArticle

Neoplasm Genes
Ovariectomy
Breast Neoplasms
Mutation
Confidence Intervals
2017

Accuracy and response time of dual biomarker model of insulin-like growth factor binding protein-1/ alpha fetoprotein (Amnioquick duo+) in comparison to placental alpha-microglobulin-1 test in diagnosis of premature rupture of membranes

Eleje, G. U., Ezugwu, E. C., Eke, A., Ikechebelu, J. I., Ezeama, C. O., Ezebialu, I. U., Ojiegbe, N. O., Obiora, C. C., Okafor, C. I., Udigwe, G. O., Nwosu, B. O. & Ezugwu, F. O., May 1 2017, In : Journal of Obstetrics and Gynaecology Research. 43, 5, p. 825-833 9 p.

Research output: Contribution to journalArticle

Insulin-Like Growth Factor Binding Protein 1
alpha-Fetoproteins
Reaction Time
Rupture
Biomarkers

Accuracy of a combined insulin-like growth factor-binding protein-1/interleukin-6 test (Premaquick) in predicting delivery in women with threatened preterm labor

Eleje, G. U., Ezugwu, E. C., Eke, A., Eleje, L. I., Ikechebelu, J. I., Ezebialu, I. U., Obiora, C. C., Nwosu, B. O., Ezeama, C. O., Udigwe, G. O., Okafor, C. I. & Ezugwu, F. O., Nov 27 2017, In : Journal of Perinatal Medicine. 45, 8, p. 915-924 10 p.

Research output: Contribution to journalReview article

Insulin-Like Growth Factor Binding Protein 1
Premature Obstetric Labor
Interleukin-6
Pregnancy
Biomarkers

Antiphospholipid antibody profile based obstetric outcomes of primary antiphospholipid syndrome: the PREGNANTS study

on behalf of the & PREGNANTS (PREGNancy in women with ANTiphospholipid Syndrome) working group, May 1 2017, In : American journal of obstetrics and gynecology. 216, 5, p. 525.e1-525.e12

Research output: Contribution to journalArticle

Antiphospholipid Antibodies
Antiphospholipid Syndrome
Obstetrics
Lupus Coagulation Inhibitor
Anticardiolipin Antibodies

Cervical cerclage in combination with other treatments for preventing preterm birth in singleton pregnancies

Eleje, G. U., Ikechebelu, J. I., Eke, A., Okam, P. C., Ezebialu, I. U. & Ilika, C. P., Nov 15 2017, In : Cochrane Database of Systematic Reviews. 2017, 11, CD012871.

Research output: Contribution to journalArticle

Cervical Cerclage
Intravaginal Administration
Pessaries
Tocolytic Agents
High-Risk Pregnancy

Comparison of the duo of insulin-like growth factor binding protein-1/alpha fetoprotein (Amnioquick duo+®) and traditional clinical assessment for diagnosing premature rupture of fetal membranes

Eleje, G. U., Ezugwu, E. C., Eke, A., Ikechebelu, J. I., Obiora, C. C., Ojiegbe, N. O., Ezebialu, I. U., Ezeama, C. O., Nwosu, B. O., Udigwe, G. O., Okafor, C. I. & Ezugwu, F. O., Jan 1 2017, In : Journal of Perinatal Medicine. 45, 1, p. 105-112 8 p.

Research output: Contribution to journalArticle

Premature Rupture Fetal Membranes
Insulin-Like Growth Factor Binding Protein 1
alpha-Fetoproteins
Rupture
Membranes

Effect of on-site training on the accuracy of blood loss estimation in a simulated obstetrics environment

Mbachu, I. I., Udigwe, G. O., Ezeama, C. O., Eleje, G. U. & Eke, A., Jun 1 2017, In : International Journal of Gynecology and Obstetrics. 137, 3, p. 345-349 5 p.

Research output: Contribution to journalArticle

Obstetrics
Blood Volume
Nigeria
Tertiary Care Centers
Health Personnel

Hepatitis B immunoglobulin during pregnancy for prevention of mother-to-child transmission of hepatitis B virus

Eke, A., Eleje, G. U., Eke, U. A., Xia, Y. & Liu, J., Feb 11 2017, In : Cochrane Database of Systematic Reviews. 2017, 2, CD008545.

Research output: Contribution to journalReview article

Hepatitis B
Hepatitis B virus
Immunoglobulins
Mothers
Pregnancy
17-alpha-Hydroxyprogesterone
Progesterone
Meta-Analysis
Randomized Controlled Trials
Pregnancy
Progesterone
Meta-Analysis
Randomized Controlled Trials
17-alpha-hydroxy-progesterone caproate
2016

A systematic review and meta-analysis of progestogen use for maintenance tocolysis after preterm labor in women with intact membranes

Eke, A., Chalaan, T., Shukr, G., Eleje, G. U. & Okafor, C. I., Jan 1 2016, In : International Journal of Gynecology and Obstetrics. 132, 1, p. 11-16 6 p.

Research output: Contribution to journalReview article

Tocolysis
Premature Obstetric Labor
Progestins
Meta-Analysis
Maintenance

Connect the Dots - November 2016

Miller, L. A., Chen, M. J., Eke, A. & Chescheir, N. C., Nov 1 2016, In : Obstetrics and gynecology. 128, 5, p. 1177-1178 2 p.

Research output: Contribution to journalComment/debate

Diagnostic performance of placental alpha-microglobulin-1 test in women with prolonged pre-labour rupture of membranes

Eleje, G. U., Ezugwu, E. C., Eke, A., Eleje, L. I., Ikechebelu, J. I., Afiadigwe, E. A., Ezugwu, F. O., Udigwe, G. O., Okafor, C. I. & Ezeama, C. O., Apr 17 2016, In : Journal of Maternal-Fetal and Neonatal Medicine. 29, 8, p. 1291-1296 6 p.

Research output: Contribution to journalArticle

Rupture
Membranes
Nigeria
Teaching Hospitals
Signs and Symptoms

Intra-abdominal saline irrigation at cesarean section: A systematic review and meta-analysis

Eke, A., Shukr, G. H., Chaalan, T. T., Nashif, S. K. & Eleje, G. U., May 18 2016, In : Journal of Maternal-Fetal and Neonatal Medicine. 29, 10, p. 1588-1594 7 p.

Research output: Contribution to journalArticle

Cesarean Section
Meta-Analysis
Confidence Intervals
Nausea
Vomiting

Risk-reducing bilateral salpingo-oophorectomy in women with BRCA1 or BRCA2 mutations

Eleje, G. U., Eke, A., Ezebialu, I. U., Ikechebelu, J. I., Ugwu, E. O. & Okonkwo, O. O., Dec 15 2016, In : Cochrane Database of Systematic Reviews. 2016, 12, CD012464.

Research output: Contribution to journalArticle

Ovariectomy
Mutation

Selective serotonin reuptake inhibitor (SSRI) use during pregnancy and risk of preterm birth: a systematic review and meta-analysis

Eke, A., Saccone, G. & Berghella, V., Nov 1 2016, In : BJOG: An International Journal of Obstetrics and Gynaecology. 123, 12, p. 1900-1907 8 p.

Research output: Contribution to journalReview article

Premature Birth
Serotonin Uptake Inhibitors
Meta-Analysis
Pregnancy
Serotonin
2015

Methods for assessing pre-induction cervical ripening

Ezebialu, I. U., Eke, A., Eleje, G. U. & Nwachukwu, C. E., Jun 12 2015, In : Cochrane Database of Systematic Reviews. 2015, 6, CD010762.

Research output: Contribution to journalReview article

Cervical Ripening
Induced Labor
Randomized Controlled Trials
Perinatal Mortality
Uterine Rupture

Palliative interventions for controlling vaginal bleeding in advanced cervical cancer

Eleje, G. U., Eke, A., Igberase, G. O., Igwegbe, A. O. & Eleje, L. I., May 1 2015, In : Cochrane Database of Systematic Reviews. 2015, 5, CD011000.

Research output: Contribution to journalReview article

Uterine Hemorrhage
Uterine Cervical Neoplasms
Radiotherapy
Interventional Radiology
Palliative Care

Perceptions of focused prenatal care among women attending two tertiary centers in Nigeria

Eleje, G. U., Onwusulu, D. N., Ezeama, C. O., Afiadigwe, E. A., Eke, A., Ikechebelu, J. I., Ugboaja, J. O. & Okwuosa, A. O., Nov 1 2015, In : International Journal of Gynecology and Obstetrics. 131, 2, p. 174-177 4 p., 8415.

Research output: Contribution to journalArticle

Prenatal Care
Nigeria
Obstetrics
Pregnant Women
Odds Ratio

Skilled birth attendance in Nigeria: A function of frequency and content of antenatal care

Okigbo, C. C. & Eke, A., Mar 1 2015, In : African Journal of Reproductive Health. 19, 1, p. 25-33 9 p.

Research output: Contribution to journalArticle

Prenatal Care
Nigeria
Parturition
Maternal Mortality
Africa South of the Sahara
2014

A comparison of prophylactic intramuscular ergometrine and oxytocin for women in the third stage of labor

Ezeama, C. O., Eleje, G. U., Ezeama, N. N., Igwegbe, A. O., Ikechebelu, J. I., Ugboaja, J. O., Ezebialu, I. U. & Eke, A., Jan 1 2014, In : International Journal of Gynecology and Obstetrics. 124, 1, p. 67-71 5 p.

Research output: Contribution to journalArticle

Third Labor Stage
Ergonovine
Oxytocin
Postpartum Hemorrhage
Oxytocics

Amnioinfusion for meconium-stained liquor in labour

Hofmeyr, G. J., Xu, H. & Eke, A., Jan 23 2014, In : Cochrane Database of Systematic Reviews. 2014, 1, CD000014.

Research output: Contribution to journalReview article

Meconium
Peripartum Period
Meconium Aspiration Syndrome
Fetal Distress
Vocal Cords

Amnioinfusion for third trimester preterm premature rupture of membranes

Hofmeyr, G. J., Eke, A. & Lawrie, T. A., Mar 30 2014, In : Cochrane Database of Systematic Reviews. 2014, 3, CD000942.

Research output: Contribution to journalReview article

Third Pregnancy Trimester
Confidence Intervals
Odds Ratio
Morbidity
Umbilical Arteries

Elderly primigravidae versus young primigravidae: a review of pregnancy outcome in a low resource setting.

Eleje, G. U., lgwegbe, A. O., Okonkwo, J. E. N., Udigwe, G. O. & Eke, A., Jan 1 2014, In : Nigerian journal of medicine : journal of the National Association of Resident Doctors of Nigeria. 23, 3, p. 220-229 10 p.

Research output: Contribution to journalArticle

Pregnancy Outcome
Pregnancy
Obstetrics
Incidence
Cephalopelvic Disproportion

Palliative interventions for controlling vaginal bleeding in cervical cancer

Eleje, G. U., Eke, A., Igberase, G. O., Igwegbe, A. O. & Eleje, L. I., Feb 21 2014, In : Cochrane Database of Systematic Reviews. 2014, 2, CD011000.

Research output: Contribution to journalArticle

Tranexamic Acid
Interventional Radiology
Uterine Hemorrhage
Palliative Care
Uterine Cervical Neoplasms
2013

Methods for assessing pre-induction cervical ripening

Ezebialu, I. U., Eke, A., Eleje, G. U. & Nwachukwu, C. E., Oct 8 2013, In : Cochrane Database of Systematic Reviews. 2013, 10, CD010762.

Research output: Contribution to journalArticle

Cervical Ripening
Induced Labor
2012

Prevalence, pattern, and determinants of placental malaria in a population of southeastern Nigerian parturients

Ezebialu, I. U., Eke, A., Ezeagwuna, D. A., Nwachukwu, C. E., Ifediata, F. & Ezebialu, C. U., Dec 1 2012, In : International Journal of Infectious Diseases. 16, 12

Research output: Contribution to journalArticle

Open Access
Malaria
Parturition
Population
Nigeria
Parity
Coitus
Postpartum Period
Population
Fear
Mothers
2011

Adult granulosa cell tumor associated with endometrial carcinoma: A case report

Ukah, C. O., Ikpeze, O. C., Eleje, G. U. & Eke, A., Aug 4 2011, In : Journal of Medical Case Reports. 5, 340.

Research output: Contribution to journalArticle

Open Access
Granulosa Cell Tumor
Endometrial Neoplasms
Endometrioid Carcinoma
Ovariectomy
Endometrium

Long-acting reversible contraception (LARC) use among adolescent females in secondary institutions in Nnewi, Nigeria

Eke, A. & Alabi-Isama, L., Feb 1 2011, In : Journal of Obstetrics and Gynaecology. 31, 2, p. 164-168 5 p.

Research output: Contribution to journalArticle

Nigeria
Contraception
Contraceptive Agents
Reproductive Health Services
Unwanted Pregnancies

Male infertility management in a Nigerian tertiary hospital

Eke, A., Okafor, C. I. & Ezebialu, I. U., Jan 1 2011, In : International Journal of Gynecology and Obstetrics. 114, 1, p. 85-86 2 p.

Research output: Contribution to journalArticle

Male Infertility
Nigeria
Tertiary Care Centers