Research output per year
Research output per year
- 1 - 50 out of 83 results
Search results
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2022
A high-affinity cocaine binding site associated with the brain acid soluble protein 1
Harraz, M. M., Malla, A. P., Semenza, E. R., Shishikura, M., Singh, M., Hwang, Y., Kang, I. G., Song, Y. J., Snowman, A. M., Cortés, P., Karuppagounder, S. S., Dawson, T. M., Dawson, V. L. & Snyder, S. H., Apr 19 2022, In: Proceedings of the National Academy of Sciences of the United States of America. 119, 16, 2200545119.Research output: Contribution to journal › Article › peer-review
Open Access -
Biliverdin reductase bridges focal adhesion kinase to Src to modulate synaptic signaling
Vasavda, C., Semenza, E. R., Liew, J., Kothari, R., Dhindsa, R. S., Shanmukha, S., Lin, A., Tokhunts, R., Ricco, C., Snowman, A. M., Albacarys, L., Pastore, F., Ripoli, C., Grassi, C., Barone, E., Kornberg, M. D., Dong, X., Paul, B. D. & Snyder, S. H., May 10 2022, In: Science signaling. 15, 733, eabh3066.Research output: Contribution to journal › Article › peer-review
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Identification of the NRF2 transcriptional network as a therapeutic target for trigeminal neuropathic pain
Vasavda, C., Xu, R., Liew, J., Kothari, R., Dhindsa, R. S., Semenza, E. R., Paul, B. D., Green, D. P., Sabbagh, M. F., Shin, J. Y., Yang, W., Snowman, A. M., Albacarys, L. K., Moghekar, A., Pardo-Villamizar, C. A., Luciano, M., Huang, J., Bettegowda, C., Kwatra, S. G., Dong, X., & 2 others, Aug 2022, In: Science Advances. 8, 31, eabo5633.Research output: Contribution to journal › Article › peer-review
Open Access -
2021
Hydrogen sulfide is neuroprotective in Alzheimer’s disease by sulfhydrating GSK3β and inhibiting Tau hyperphosphorylation
Giovinazzo, D., Bursac, B., Sbodio, J. I., Nalluru, S., Vignane, T., Snowman, A. M., Albacarys, L. M., Sedlak, T. W., Torregrossa, R., Whiteman, M., Filipovic, M. R., Snyder, S. H. & Paul, B. D., Jan 26 2021, In: Proceedings of the National Academy of Sciences of the United States of America. 118, 4, e2017225118.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
2019
Bilirubin Links Heme Metabolism to Neuroprotection by Scavenging Superoxide
Vasavda, C., Kothari, R., Malla, A. P., Tokhunts, R., Lin, A., Ji, M., Ricco, C., Xu, R., Saavedra, H. G., Sbodio, J. I., Snowman, A. M., Albacarys, L., Hester, L., Sedlak, T. W., Paul, B. D. & Snyder, S. H., Oct 17 2019, In: Cell Chemical Biology. 26, 10, p. 1450-1460.e7Research output: Contribution to journal › Article › peer-review
Open Access23 Scopus citations -
The glutathione cycle shapes synaptic glutamate activity
Sedlak, T. W., Paul, B. D., Parker, G. M., Hester, L. D., Snowman, A. M., Taniguchi, Y., Kamiya, A., Snyder, S. H. & Sawa, A., Feb 12 2019, In: Proceedings of the National Academy of Sciences of the United States of America. 116, 7, p. 2701-2706 6 p.Research output: Contribution to journal › Article › peer-review
Open Access31 Scopus citations -
2018
Dimethyl fumarate targets GAPDH and aerobic glycolysis to modulate immunity
Kornberg, M. D., Bhargava, P., Kim, P. M., Putluri, V., Snowman, A. M., Putluri, N., Calabresi, P. A. & Snyder, S. H., Apr 27 2018, In: Science. 360, 6387, p. 449-453 5 p.Research output: Contribution to journal › Article › peer-review
Open Access195 Scopus citations -
Histone H2AX deficiency causes neurobehavioral deficits and impaired redox homeostasis
Weyemi, U., Paul, B. D., Snowman, A. M., Jailwala, P., Nussenzweig, A., Bonner, W. M. & Snyder, S. H., Dec 1 2018, In: Nature communications. 9, 1, 1526.Research output: Contribution to journal › Article › peer-review
Open Access12 Scopus citations -
Inositol polyphosphate multikinase inhibits angiogenesis via inositol pentakisphosphate-induced HIF-1α degradation
Fu, C., Tyagi, R., Chin, A. C., Rojas, T., Li, R. J., Guha, P., Bernstein, I. A., Rao, F., Xu, R., Cha, J. Y., Xu, J., Snowman, A. M., Semenza, G. L. & Snyder, S. H., Feb 2 2018, In: Circulation research. 122, 3, p. 457-472 16 p.Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations -
2017
Neuronal migration is mediated by inositol hexakisphosphate kinase 1 via α-actinin and focal adhesion kinase
Fu, C., Xu, J., Cheng, W., Rojas, T., Chin, A. C., Snowman, A. M., Harraz, M. M. & Snyder, S. H., Feb 21 2017, In: Proceedings of the National Academy of Sciences of the United States of America. 114, 8, p. 2036-2041 6 p.Research output: Contribution to journal › Article › peer-review
Open Access14 Scopus citations -
2015
Inositol hexakisphosphate kinase-3 regulates the morphology and synapse formation of cerebellar purkinje cells via spectrin/adducin
Fu, C., Xu, J., Li, R. J., Crawford, X. A., Khan, A. B., Ma, T. M., Cha, J. Y., Snowman, A. M., Pletnikov, M. V. & Snyder, S. H., Aug 5 2015, In: Journal of Neuroscience. 35, 31, p. 11056-11067 12 p.Research output: Contribution to journal › Article › peer-review
Open Access32 Scopus citations -
2014
Cystathionine γ-lyase deficiency mediates neurodegeneration in Huntington's disease
Paul, B. D., Sbodio, J. I., Xu, R., Vandiver, M. S., Cha, J. Y., Snowman, A. M. & Snyder, S. H., 2014, In: Nature. 508, 7498, p. 96-100 5 p.Research output: Contribution to journal › Article › peer-review
Open Access208 Scopus citations -
2013
Erratum: Inositol polyphosphate multikinase is a coactivator of p53-mediated transcription and cell death (Science Signaling (2013) 6: 273 (er1) Doi: 10.1126/scisignal.6273er1)
Xu, R., Sen, N., Paul, B. D., Snowman, A. M., Rao, F., Vandiver, M. S., Xu, J. & Snyder, S. H., Apr 30 2013, In: Science signaling. 6, 273, p. er1Research output: Contribution to journal › Comment/debate › peer-review
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Inositol polyphosphate multikinase is a coactivator of p53-mediated transcription and cell death
Xu, R., Sen, N., Paul, B. D., Snowman, A. M., Rao, F., Vandiver, M. S., Xu, J. & Snyder, S. H., Apr 2 2013, In: Science signaling. 6, 269, p. ra22Research output: Contribution to journal › Article › peer-review
Open Access35 Scopus citations -
Sulfhydration mediates neuroprotective actions of parkin
Vandiver, M. S., Paul, B. D., Xu, R., Karuppagounder, S., Rao, F., Snowman, A. M., Seok Ko, H., Il Lee, Y., Dawson, V. L., Dawson, T. M., Sen, N. & Snyder, S. H., 2013, In: Nature communications. 4, 1626.Research output: Contribution to journal › Article › peer-review
Open Access166 Scopus citations -
2012
Erratum: Protein pyrophosphorylation by inositol pyrophosphates is a posttranslational event (Proceedings of the National Academy of Sciences of the United States of America (2007) 104, 39, (15305-15310) DOI: 10.1073/pnas. 0707338104)
Bhandari, R., Saiardi, A., Ahmadibeni, Y., Snowman, A. M., Resnick, A. C., Kristiansen, T. Z., Molina, H., Pandey, A., Werner, J. K., Juluri, K. R., Xu, Y., Prestwich, G. D., Parang, K. & Snyder, S. H., Dec 18 2012, In: Proceedings of the National Academy of Sciences of the United States of America. 109, 51, p. 21171-21173 3 p.Research output: Contribution to journal › Comment/debate › peer-review
Open Access -
2011
Amino acid signaling to mTOR mediated by inositol polyphosphate multikinase
Kim, S., Kim, S. F., Maag, D., Maxwell, M. J., Resnick, A. C., Juluri, K. R., Chakraborty, A., Koldobskiy, M. A., Cha, S. H., Barrow, R., Snowman, A. M. & Snyder, S. H., Feb 2 2011, In: Cell Metabolism. 13, 2, p. 215-221 7 p.Research output: Contribution to journal › Article › peer-review
Open Access96 Scopus citations -
Casein kinase-2 mediates cell survival through phosphorylation and degradation of inositol hexakisphosphate kinase-2
Chakraborty, A., Werner, J. K., Koldobskiy, M. A., Mustafa, A. K., Juluri, K. R., Pietropaoli, J., Snowman, A. M. & Snyder, S. H., Feb 8 2011, In: Proceedings of the National Academy of Sciences of the United States of America. 108, 6, p. 2205-2209 5 p.Research output: Contribution to journal › Article › peer-review
Open Access33 Scopus citations -
Inositol polyphosphate multikinase is a physiologic PI3-kinase that activates Akt/PKB
Maag, D., Maxwell, M. J., Hardesty, D. A., Boucher, K. L., Choudhari, N., Hanno, A. G., Ma, J. F., Snowman, A. S., Pietropaoli, J. W., Xu, R., Storm, P. B., Saiardi, A., Snyder, S. H. & Resnick, A. C., Jan 25 2011, In: Proceedings of the National Academy of Sciences of the United States of America. 108, 4, p. 1391-1396 6 p.Research output: Contribution to journal › Article › peer-review
Open Access70 Scopus citations -
2010
GAPDH mediates nitrosylation of nuclear proteins
Kornberg, M. D., Sen, N., Hara, M. R., Juluri, K. R., Nguyen, J. V. K., Snowman, A. M., Law, L., Hester, L. D. & Snyder, S. H., Nov 2010, In: Nature cell biology. 12, 11, p. 1094-1100 7 p.Research output: Contribution to journal › Article › peer-review
Open Access262 Scopus citations -
Inositol pyrophosphates inhibit akt signaling, thereby regulating insulin sensitivity and weight gain
Chakraborty, A., Koldobskiy, M. A., Bello, N. T., Maxwell, M., Potter, J. J., Juluri, K. R., Maag, D., Kim, S., Huang, A. S., Dailey, M. J., Saleh, M., Snowman, A. M., Moran, T. H., Mezey, E. & Snyder, S. H., Dec 10 2010, In: Cell. 143, 6, p. 897-910 14 p.Research output: Contribution to journal › Article › peer-review
Open Access230 Scopus citations -
P53-mediated apoptosis requires inositol hexakisphosphate kinase-2
Koldobskiy, M. A., Chakraborty, A., Werner, J. K., Snowman, A. M., Juluri, K. R., Vandiver, M. S., Kim, S., Heletz, S. & Snyder, S. H., Dec 7 2010, In: Proceedings of the National Academy of Sciences of the United States of America. 107, 49, p. 20947-20951 5 p.Research output: Contribution to journal › Article › peer-review
Open Access66 Scopus citations -
2008
HSP90 regulates cell survival via inositol hexakisphosphate kinase-2
Chakraborty, A., Koldobskiy, M. A., Sixt, K. M., Juluri, K. R., Mustafa, A. K., Snowman, A. M., Van Rossum, D. B., Patterson, R. L. & Snyder, S. H., Jan 29 2008, In: Proceedings of the National Academy of Sciences of the United States of America. 105, 4, p. 1134-1139 6 p.Research output: Contribution to journal › Article › peer-review
Open Access83 Scopus citations -
2007
Antipsychotic drug-induced weight gain mediated by histamine H1 receptor-linked activation of hypothalamic AMP-kinase
Kim, S. F., Huang, A. S., Snowman, A. M., Teuscher, C. & Snyder, S. H., Feb 27 2007, In: Proceedings of the National Academy of Sciences of the United States of America. 104, 9, p. 3456-3459 4 p.Research output: Contribution to journal › Article › peer-review
Open Access296 Scopus citations -
Protein pyrophosphorylation by inositol pyrophosphates is a posttranslational event
Bhandari, R., Saiardi, A., Ahmadibeni, Y., Snowman, A. M., Adam, R. C., Kristiansen, T. Z., Molina, H., Pandey, A., Werner, J. K., Juluri, K. R., Ku, Y., Prestwich, G. D., Parang, K. & Snyder, S. H., Sep 25 2007, In: Proceedings of the National Academy of Sciences of the United States of America. 104, 39, p. 15305-15310 6 p.Research output: Contribution to journal › Article › peer-review
Open Access147 Scopus citations -
2005
Inositol polyphosphate multikinase is a nuclear PI3-kinase with transcriptional regulatory activity
Resnick, A. C., Snowman, A. M., Kang, B. M., Hurt, K. J., Snyder, S. H. & Saiardi, A., Sep 6 2005, In: Proceedings of the National Academy of Sciences of the United States of America. 102, 36, p. 12783-12788 6 p.Research output: Contribution to journal › Article › peer-review
Open Access89 Scopus citations -
Inositol pyrophosphates regulate cell death and telomere length through phosphoinositide 3-kinase-related protein kinases
Saiardi, A., Resnick, A. C., Snowman, A. M., Wendland, B. & Snyder, S. H., Feb 8 2005, In: Proceedings of the National Academy of Sciences of the United States of America. 102, 6, p. 1911-1914 4 p.Research output: Contribution to journal › Article › peer-review
Open Access130 Scopus citations -
Protein phophorylation mechanism involving IP7 instead of ATP holds clues for new drugs
Saiardi, Bhandari, Snyder, Resnick, A. & Snowman, A., Jan 2005, In: Cancer Biology and Therapy. 4, 1Research output: Contribution to journal › Comment/debate › peer-review
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2004
Phosphorylation of proteins by inositol pyrophosphates
Saiardi, A., Bhandari, R., Resnick, A. C., Snowman, A. M. & Snyder, S. H., Dec 17 2004, In: Science. 306, 5704, p. 2101-2105 5 p.Research output: Contribution to journal › Article › peer-review
225 Scopus citations -
2002
Neuronal nitric-oxide synthase localization mediated by a ternary complex with synapsin and CAPON
Jaffrey, S. R., Benfenati, F., Snowman, A. M., Czernik, A. J. & Snyder, S. H., Mar 5 2002, In: Proceedings of the National Academy of Sciences of the United States of America. 99, 5, p. 3199-3204 6 p.Research output: Contribution to journal › Article › peer-review
Open Access96 Scopus citations -
2001
Identification and Characterization of a Novel Inositol Hexakisphosphate Kinase
Saiardi, A., Nagata, E., Luo, H. R., Snowman, A. M. & Snyder, S. H., Oct 19 2001, In: Journal of Biological Chemistry. 276, 42, p. 39179-39185 7 p.Research output: Contribution to journal › Article › peer-review
Open Access109 Scopus citations -
Mammalian inositol polyphosphate multikinase synthesizes inositol 1,4,5-trisphosphate and an inositol pyrophosphate
Saiardi, A., Nagata, E., Luo, H. R., Sawa, A., Luo, X., Snowman, A. M. & Snyder, S. H., Feb 27 2001, In: Proceedings of the National Academy of Sciences of the United States of America. 98, 5, p. 2306-2311 6 p.Research output: Contribution to journal › Article › peer-review
Open Access90 Scopus citations -
1999
Synthesis of diphosphoinositol pentakisphosphate by a newly identified family of higher inositol polyphosphate kinases
Saiardi, A., Erdjument-Bromage, H., Snowman, A. M., Tempst, P. & Snyder, S. H., Nov 18 1999, In: Current Biology. 9, 22, p. 1323-1326 4 p.Research output: Contribution to journal › Article › peer-review
Open Access286 Scopus citations -
1998
CAPON: A protein associated with neuronal nitric oxide synthase that regulates its interactions with PSD95
Jaffrey, S. R., Snowman, A. M., Eliasson, M. J. L., Cohen, N. A. & Snyder, S. H., Jan 1998, In: Neuron. 20, 1, p. 115-124 10 p.Research output: Contribution to journal › Article › peer-review
Open Access284 Scopus citations -
Profiling established cell lines as a means to screening diversity
Good, E., Perschke, S., Lopez, R., Chang, S., Kinsler, A., Snowman, A., Lacombe, J., Fedock, M., Zeppetello, R. & Zysk, J. R., 1998, In: Journal of Biomolecular Screening. 3, 3, p. 231-236 6 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
1996
Cloned and expressed rat Ca2+-sensing receptor: Differential cooperative responses to calcium and magnesium
Ruat, M., Snowman, A. M., Hester, L. D. & Snyder, S. H., Mar 15 1996, In: Journal of Biological Chemistry. 271, 11, p. 5972-5975 4 p.Research output: Contribution to journal › Article › peer-review
Open Access109 Scopus citations -
1995
Calcium sensing receptor: Molecular cloning in rat and localization to nerve terminals
Ruat, M., Molliver, M. E., Snowman, A. M. & Snyder, S. H., Apr 11 1995, In: Proceedings of the National Academy of Sciences of the United States of America. 92, 8, p. 3161-3165 5 p.Research output: Contribution to journal › Article › peer-review
Open Access335 Scopus citations -
Clozapine: Selective Labeling of Sites Resembling 5HT6 Serotonin Receptors May Reflect Psychoactive Profile
Glatt, C. E., Snowman, A. M., Sibley, D. R. & Snyder, S. H., May 1995, In: Molecular Medicine. 1, 4, p. 398-406 9 p.Research output: Contribution to journal › Article › peer-review
Open Access57 Scopus citations -
Receptor binding profile suggests multiple mechanisms of action are responsible for ibogaine's putative anti-addictive activity
Sweetnam, P. M., Lancaster, J., Snowman, A., Collins, J. L., Perschke, S., Bauer, C. & Ferkany, J., Apr 1995, In: Psychopharmacology. 118, 4, p. 369-376 8 p.Research output: Contribution to journal › Article › peer-review
86 Scopus citations -
1994
Endothelial nitric oxide synthase localized to hippocampal pyramidal cells: Implications for synaptic plasticity
Dinerman, J. L., Dawson, T. M., Schell, M. J., Snowman, A. & Snyder, S. H., May 10 1994, In: Proceedings of the National Academy of Sciences of the United States of America. 91, 10, p. 4214-4218 5 p.Research output: Contribution to journal › Article › peer-review
Open Access599 Scopus citations -
The association of endogenous Goα with the purified ω-conotoxin GVIA receptor
McEnery, M. W., Snowman, A. M. & Snyder, S. H., Jan 7 1994, In: Journal of Biological Chemistry. 269, 1, p. 5-8 4 p.Research output: Contribution to journal › Article › peer-review
23 Scopus citations -
1993
Immunological Characterization of Proteins Associated with the Purified Omega‐conotoxin GVIA Receptor
McENERY, M. W., SNOWMAN, A. M., SEAGAR, M. J., COPELAND, T. D. & TAKAHASHI, M., Dec 1993, In: Annals of the New York Academy of Sciences. 707, 1, p. 386-391 6 p.Research output: Contribution to journal › Article › peer-review
5 Scopus citations -
Macrophage nitric oxide synthase gene: Two upstream regions mediate induction by interferon γ and lipopolysaccharide
Lowenstein, C. J., Alley, E. W., Raval, P., Snowman, A. M., Snyder, S. H., Russell, S. W. & Murphy, W. J., Oct 15 1993, In: Proceedings of the National Academy of Sciences of the United States of America. 90, 20, p. 9730-9734 5 p.Research output: Contribution to journal › Article › peer-review
982 Scopus citations -
1992
Erratum: Purified ω-conotoxin GVIA receptor of rat brain resembles a dihydropyridine-sensitive L-type calcium channel (Proc. Natl. Acad. Sci. USA (December 15, 1991) 88 (11095-11099))
McEnery, M. W., Snowman, A. M., Sharp, A. H., Adams, M. E. & Snyder, S. H., 1992, In: Proceedings of the National Academy of Sciences of the United States of America. 89, 7, p. 3164 1 p.Research output: Contribution to journal › Comment/debate › peer-review
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High brain densities of the immunophilin FKBP colocalized with calcineurin
Steiner, J. P., Dawson, T. M., Fotuhi, M., Glatt, C. E., Snowman, A. M., Cohen, N. & Snyder, S. H., 1992, In: Nature. 358, 6387, p. 584-587 4 p.Research output: Contribution to journal › Article › peer-review
316 Scopus citations -
Isolation of the mitochondrial benzodiazepine receptor: Association with the voltage-dependent anion channel and the adenine nucleotide carrier
Mcenery, M. W., Snowman, A. M., Trifiletti, R. R. & Snyder, S. H., 1992, In: Proceedings of the National Academy of Sciences of the United States of America. 89, 8, p. 3170-3174 5 p.Research output: Contribution to journal › Article › peer-review
Open Access647 Scopus citations -
1991
[3H]opipramol labels a novel binding site and a receptors in rat brain membranes
Ferris, C. D., Hirsch, D. J., Brooks, B. P., Snowman, A. M. & Snyder, S. H., Feb 1991, In: Molecular Pharmacology. 39, 2, p. 199-204 6 p.Research output: Contribution to journal › Article › peer-review
22 Scopus citations -
Evidence for Subtypes of the ω‐Conotoxin GVIA Receptor: Identification of the Properties Intrinsic to the High‐Affinity Receptor
McENERY, MAUREEN. W., SNOWMAN, ADELE. M. & SNYDER, SOLOMON. H., Oct 1991, In: Annals of the New York Academy of Sciences. 635, 1, p. 435-437 3 p.Research output: Contribution to journal › Article › peer-review
6 Scopus citations -
Purified ω-conotoxin GVIA receptor of rat brain resembles a dihydropyridine-sensitive L-type calcium channel
Mcenery, M. W., Snowman, A. M., Sharp, A. H., Adams, M. E. & Snyder, S. H., 1991, In: Proceedings of the National Academy of Sciences of the United States of America. 88, 24, p. 11095-11099 5 p.Research output: Contribution to journal › Article › peer-review
89 Scopus citations -
1990
Cetirizine: Actions on neurotransmitter receptors
Snowman, A. M. & Snyder, S. H., Dec 1990, In: The Journal of allergy and clinical immunology. 86, 6 PART 2, p. 1025-1028 4 p.Research output: Contribution to journal › Article › peer-review
40 Scopus citations