Abhay R Moghekar

Associate Professor

20022020

Research output per year

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2020

Brain Oxygen Extraction Is Differentially Altered by Alzheimer's and Vascular Diseases

Jiang, D., Lin, Z., Liu, P., Sur, S., Xu, C., Hazel, K., Pottanat, G., Darrow, J., Pillai, J. J., Yasar, S., Rosenberg, P., Moghekar, A. R., Albert, M. & Lu, H., 2020, (Accepted/In press) In : Journal of Magnetic Resonance Imaging.

Research output: Contribution to journalArticle

Cognitive reserve and rate of change in Alzheimer's and cerebrovascular disease biomarkers among cognitively normal individuals

Pettigrew, C., Soldan, A., Zhu, Y., Cai, Q., Wang, M. C., Moghekar, A., Miller, M. I., Singh, B., Martinez, O., Fletcher, E., DeCarli, C. & Albert, M., Apr 2020, In : Neurobiology of aging. 88, p. 33-41 9 p.

Research output: Contribution to journalArticle

Open Access

General Anesthesia Alters Intracranial Venous Pressures During Transverse Sinus Stenting

El Mekabaty, A., Gottschalk, A., Moghekar, A., Obusez, E., Khan, M., Chung, C., Spiotta, A., Luciano, M. G. & Hui, F. K., Jun 2020, In : World neurosurgery. 138, p. e712-e717

Research output: Contribution to journalArticle

High-resolution MRI for evaluation of ventriculostomy tubes: Assessment of positioning and proximal patency

Blitz, A. M., Huynh, P. P., Bonham, L. W., Gujar, S. K., Sorte, D. E., Moghekar, A., Luciano, M. G. & Rigamonti, D., Jan 1 2020, In : American Journal of Neuroradiology. 41, 1, p. 57-63 7 p.

Research output: Contribution to journalArticle

Multiplexed Phosphoproteomic Study of Brain in Patients with Alzheimer's Disease and Age-Matched Cognitively Healthy Controls

Sathe, G., Mangalaparthi, K. K., Jain, A., Darrow, J., Troncoso, J., Albert, M., Moghekar, A. & Pandey, A., Apr 2020, In : OMICS A Journal of Integrative Biology. 24, 4, p. 216-227 12 p.

Research output: Contribution to journalArticle

Standardized regression-based clinical change score cutoffs for normal pressure hydrocephalus

Davis, A., Yasar, S., Emerman, I., Gulyani, S., Khingelova, K., Rao, A., Manthripragada, L., Luciano, M. & Moghekar, A., Apr 16 2020, In : BMC neurology. 20, 1, 140.

Research output: Contribution to journalArticle

Open Access

The clinical spectrum of hydrocephalus in adults: Report of the first 517 patients of the Adult Hydrocephalus Clinical Research Network registry

Williams, M. A., Nagel, S. J., Luciano, M. G., Relkin, N., Zwimpfer, T. J., Katzen, H., Holubkov, R., Moghekar, A., Wisoff, J. H., McKhann, G. M., Golomb, J., Edwards, R. J. & Hamilton, M. G., Jun 2020, In : Journal of neurosurgery. 132, 6, p. 1773-1784 12 p.

Research output: Contribution to journalArticle

White matter hyperintensities and CSF Alzheimer disease biomarkers in preclinical Alzheimer disease

BIOCARD Research Team, Mar 3 2020, In : Neurology. 94, 9, p. e950-e960

Research output: Contribution to journalArticle

2019

ATN profiles among cognitively normal individuals and longitudinal cognitive outcomes

Soldan, A., Pettigrew, C., Fagan, A. M., Schindler, S. E., Moghekar, A., Fowler, C., Li, Q. X., Collins, S. J., Carlsson, C., Asthana, S., Masters, C. L., Johnson, S., Morris, J. C., Albert, M. & Gross, A. L., Apr 2 2019, In : Neurology. 92, 14, p. E1567-E1579

Research output: Contribution to journalArticle

Brain oxygen extraction by using MRI in older individuals: Relationship to apolipoprotein e genotype and amyloid burden

Lin, Z., Sur, S., Soldan, A., Pettigrew, C., Miller, M., Oishi, K., Bilgel, M., Moghekar, A., Pillai, J. J., Albert, M. & Lu, H., 2019, In : RADIOLOGY. 292, 1, p. 140-148 9 p.

Research output: Contribution to journalArticle

Identifying changepoints in biomarkers during the preclinical phase of Alzheimer's disease

Younes, L., Albert, M., Moghekar, A. R., Soldan, A., Pettigrew, C. & Miller, M. I., Jan 1 2019, In : Frontiers in Aging Neuroscience. 11, APR, 74.

Research output: Contribution to journalArticle

Open Access
Open Access

Quantitative Proteomic Profiling of Cerebrospinal Fluid to Identify Candidate Biomarkers for Alzheimer's Disease

Sathe, G., Na, C-H., Renuse, S., Madugundu, A. K., Albert, M., Moghekar, A. R. & Pandey, A., Jan 1 2019, (Accepted/In press) In : Proteomics - Clinical Applications. 1800105.

Research output: Contribution to journalArticle

Tau pathology in cognitively normal older adults

Ziontz, J., Bilgel, M., Shafer, A. T., Moghekar, A., Elkins, W., Helphrey, J., Gomez, G., June, D., McDonald, M. A., Dannals, R. F., Azad, B. B., Ferrucci, L., Wong, D. F. & Resnick, S. M., Dec 2019, In : Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring. 11, p. 637-645 9 p.

Research output: Contribution to journalArticle

Open Access

The occipital emissary vein: A possible marker for pseudotumor cerebri

Hedjoudje, A., Piveteau, A., Gonzalez-Campo, C., Moghekar, A., Gailloud, P. & Millán, D. S., Jun 1 2019, In : American Journal of Neuroradiology. 40, 6, p. 973-978 6 p.

Research output: Contribution to journalArticle

2018

Does phase-contrast imaging through the cerebral aqueduct predict the outcome of lumbar CSF drainage or shunt surgery in patients with suspected adult hydrocephalus?

Blitz, A. M., Shin, J., Balédent, O., Pagé, G., Bonham, L. W., Herzka, D. A., Moghekar, A. R. & Rigamonti, D., Dec 1 2018, In : American Journal of Neuroradiology. 39, 12, p. 2224-2230 7 p.

Research output: Contribution to journalArticle

Does the Presence or Absence of DESH Predict Outcomes in Adult Hydrocephalus?

Ahmed, A. K., Luciano, M., Moghekar, A. R., Shin, J., Aygun, N., Sair, H., Rigamonti, D. & Blitz, A. M., Nov 1 2018, In : AJNR. American journal of neuroradiology. 39, 11, p. 2022-2026 5 p.

Research output: Contribution to journalArticle

Neuropathologic, genetic, and longitudinal cognitive profiles in primary age-related tauopathy (PART) and Alzheimer's disease

Bell, W. R., An, Y., Kageyama, Y., English, C., Rudow, G. L., Pletnikova, O., Thambisetty, M., O'Brien, R., Moghekar, A. R., Albert, M., Rabins, P. V., Resnick, S. M. & Troncoso, J. C., Jan 1 2018, (Accepted/In press) In : Alzheimer's and Dementia.

Research output: Contribution to journalArticle

Non-contrast MR imaging of blood-brain barrier permeability to water

Lin, Z., Li, Y., Su, P., Mao, D., Wei, Z., Pillai, J., Moghekar, A. R., van Osch, M., Ge, Y. & Lu, H., Jan 1 2018, (Accepted/In press) In : Magnetic Resonance in Medicine.

Research output: Contribution to journalArticle

Phosphotyrosine profiling of human cerebrospinal fluid

Sathe, G., Na, C. H., Renuse, S., Madugundu, A., Albert, M., Moghekar, A. & Pandey, A., Sep 12 2018, In : Clinical Proteomics. 15, 1, 29.

Research output: Contribution to journalArticle

Predicting progression from normal cognition to mild cognitive impairment for individuals at 5 years

Albert, M., Zhu, Y., Moghekar, A., Mori, S., Miller, M. I., Soldan, A., Pettigrew, C., Selnes, O., Li, S. & Wang, M. C., Mar 1 2018, In : Brain. 141, 3, p. 877-887 11 p.

Research output: Contribution to journalArticle

Sex-specific genetic predictors of Alzheimer’s disease biomarkers

Alzheimer’s Disease Neuroimaging Initiative (ADNI) & The Alzheimer Disease Genetics Consortium (Adgc), Dec 1 2018, In : Acta neuropathologica. 136, 6, p. 857-872 16 p.

Research output: Contribution to journalArticle

Toward dynamic lumbar puncture guidance using needle-based single-element ultrasound imaging

Zhang, H. K., Kim, Y., Lin, M., Paredes, M., Kannan, K., Moghekar, A. R., Durr, N. J. & Boctor, E., Apr 1 2018, In : Journal of Medical Imaging. 5, 2, 021224.

Research output: Contribution to journalArticle

2017

Abstracts from Hydrocephalus 2016

Adam, A., Robison, J., Lu, J., Jose, R., Badran, N., Vivas-Buitrago, T., Rigamonti, D., Sattar, A., Omoush, O., Hammad, M., Dawood, M., Maghaslah, M., Belcher, T., Carson, K., Hoffberger, J., Jusué Torres, I., Foley, S., Yasar, S., Thai, Q. A., Wemmer, J. & 235 others, Klinge, P., Al-Mutawa, L., Al-Ghamdi, H., Carson, K. A., Asgari, M., de Zélicourt, D., Kurtcuoglu, V., Garnotel, S., Salmon, S., Balédent, O., Lokossou, A., Page, G., Balardy, L., Czosnyka, Z., Payoux, P., Schmidt, E. A., Zitoun, M., Sevestre, M. A., Alperin, N., Baudracco, I., Craven, C., Matloob, S., Thompson, S., Haylock Vize, P., Thorne, L., Watkins, L. D., Toma, A. K., Bechter, K., Pong, A. C., Jugé, L., Bilston, L. E., Cheng, S., Bradley, W., Hakim, F., Ramón, J. F., Cárdenas, M. F., Davidson, J. S., García, C., González, D., Bermúdez, S., Useche, N., Mejía, J. A., Mayorga, P., Cruz, F., Martinez, C., Matiz, M. C., Vallejo, M., Ghotme, K., Soto, H. A., Riveros, D., Buitrago, A., Mora, M., Murcia, L., Bermudez, S., Cohen, D., Dasgupta, D., Curtis, C., Domínguez, L., Remolina, A. J., Grijalba, M. A., Whitehouse, K. J., Edwards, R. J., Eleftheriou, A., Lundin, F., Fountas, K. N., Kapsalaki, E. Z., Smisson, H. F., Robinson, J. S., Fritsch, M. J., Arouk, W., Garzon, M., Kang, M., Sandhu, K., Baghawatti, D., Aquilina, K., James, G., Thompson, D., Gehlen, M., Schmid Daners, M., Eklund, A., Malm, J., Gomez, D., Guerra, M., Jara, M., Flores, M., Vío, K., Moreno, I., Rodríguez, S., Ortega, E., Rodríguez, E. M., McAllister, J. P., Guerra, M. M., Morales, D. M., Sival, D., Jimenez, A., Limbrick, D. D., Ishikawa, M., Yamada, S., Yamamoto, K., Junkkari, A., Häyrinen, A., Rauramaa, T., Sintonen, H., Nerg, O., Koivisto, A. M., Roine, R. P., Viinamäki, H., Soininen, H., Luikku, A., Jääskeläinen, J. E., Leinonen, V., Kehler, U., Lilja-Lund, O., Kockum, K., Larsson, E. M., Riklund, K., Söderström, L., Hellström, P., Laurell, K., Kojoukhova, M., Sutela, A., Vanninen, R., Vanha, K. I., Timonen, M., Rummukainen, J., Korhonen, V., Helisalmi, S., Solje, E., Remes, A. M., Huovinen, J., Paananen, J., Hiltunen, M., Kurki, M., Martin, B., Loth, F., Luciano, M., Luikku, A. J., Hall, A., Herukka, S. K., Mattila, J., Lötjönen, J., Alafuzoff, I., Jurjević, I., Miyajima, M., Nakajima, M., Murai, H., Shin, T., Kawaguchi, D., Akiba, C., Ogino, I., Karagiozov, K., Arai, H., Reis, R. C., Teixeira, M. J., Valêncio, C. G., da Vigua, D., Almeida-Lopes, L., Mancini, M. W., Pinto, F. C. G., Maykot, R. H., Calia, G., Tornai, J., Silvestre, S. S. S., Mendes, G., Sousa, V., Bezerra, B., Dutra, P., Modesto, P., Oliveira, M. F., Petitto, C. E., Pulhorn, H., Chandran, A., McMahon, C., Rao, A. S., Jumaly, M., Solomon, D., Moghekar, A., Relkin, N., Hamilton, M., Katzen, H., Williams, M., Bach, T., Zuspan, S., Holubkov, R., Rigamonti, A., Clemens, G., Sharkey, P., Sanyal, A., Sankey, E., Rigamonti, K., Naqvi, S., Hung, A., Schmidt, E., Ory-Magne, F., Gantet, P., Guenego, A., Januel, A. C., Tall, P., Fabre, N., Mahieu, L., Cognard, C., Gray, L., Buttner-Ennever, J. A., Takagi, K., Onouchi, K., Thompson, S. D., Thorne, L. D., Tully, H. M., Wenger, T. L., Kukull, W. A., Doherty, D., Dobyns, W. B., Moran, D., Vakili, S., Patel, M. A., Elder, B., Goodwin, C. R., Crawford, J. A., Pletnikov, M. V., Xu, J., Blitz, A., Herzka, D. A., Guerrero-Cazares, H., Quiñones-Hinojosa, A., Mori, S., Saavedra, P., Treviño, H., Maitani, K., Ziai, W. C., Eslami, V., Nekoovaght-Tak, S., Dlugash, R., Yenokyan, G., McBee, N. & Hanley, D. F., Jun 7 2017, In : Fluids and barriers of the CNS. 14, 1 p.

Research output: Contribution to journalArticle

Open Access

Alpha-2 macroglobulin in Alzheimer's disease: A marker of neuronal injury through the RCAN1 pathway

Varma, V. R., Varma, S., An, Y., Hohman, T. J., Seddighi, S., Casanova, R., Beri, A., Dammer, E. B., Seyfried, N. T., Pletnikova, O., Moghekar, A. R., Wilson, M. R., Lah, J. J., O'Brien, R. J., Levey, A. I., Troncoso, J. C., Albert, M. & Thambisetty, M., Jan 1 2017, In : Molecular Psychiatry. 22, 1, p. 13-23 11 p.

Research output: Contribution to journalArticle

Alzheimer’s disease pathology and shunt surgery outcome in normal pressure hydrocephalus

Yasar, S., Jusue-Torres, I., Lu, J., Robison, J., Patel, M. A., Crain, B., Carson, K. A., Hoffberger, J., Batra, S., Sankey, E., Moghekar, A. & Rigamonti, D., Aug 2017, In : PloS one. 12, 8, e0182288.

Research output: Contribution to journalArticle

Cognitive reserve and long-term change in cognition in aging and preclinical Alzheimer's disease

the BIOCARD Research Team, Dec 1 2017, In : Neurobiology of Aging. 60, p. 164-172 9 p.

Research output: Contribution to journalArticle

Genome-wide association study identifies four novel loci associated with Alzheimer’s endophenotypes and disease modifiers

Alzheimer’s Disease Neuroimaging Initiative (ADNI) & The Alzheimer Disease Genetic Consortium (ADGC), May 1 2017, In : Acta neuropathologica. 133, 5, p. 839-856 18 p.

Research output: Contribution to journalArticle

Predictors for venous sinus stent retreatment in patients with idiopathic intracranial hypertension

El Mekabaty, A., Obuchowski, N. A., Luciano, M., John, S., Chung, C. Y., Moghekar, A. R., Jones, S. & Hui, F., Dec 1 2017, In : Journal of NeuroInterventional Surgery. 9, 12, p. 1228-1232 5 p.

Research output: Contribution to journalArticle

Progressive medial temporal lobe atrophy during preclinical Alzheimer's disease

the BIOCARD Research Team, 2017, In : NeuroImage: Clinical. 16, p. 439-446 8 p.

Research output: Contribution to journalArticle

The impact of surgical resection on headache disability and quality of life in patients with colloid cyst

Kone, L., Chaichana, K. L., Rincon-Torroella, J., Snyman, C., Moghekar, A. & Quiñones-Hinojosa, A., Apr 1 2017, In : Cephalalgia. 37, 5, p. 442-451 10 p.

Research output: Contribution to journalArticle

Venous Sinus Stenting in the Management of Patients with Intracranial Hypertension Manifesting with Skull Base Cerebrospinal Fluid Leaks

Iyer, R. R., Solomon, D., Moghekar, A., Goodwin, C. R., Stewart, C. M., Ishii, M., Gailloud, P. & Gallia, G. L., Oct 1 2017, In : World Neurosurgery. 106, p. 103-112 10 p.

Research output: Contribution to journalArticle

2016

Cortical thickness in relation to clinical symptom onset in preclinical AD

the BIOCARD Research Team, 2016, In : NeuroImage: Clinical. 12, p. 116-122 7 p.

Research output: Contribution to journalArticle

Hypothetical preclinical Alzheimer disease groups and longitudinal cognitive change

Soldan, A., Pettigrew, C., Cai, Q., Wang, M. C., Moghekar, A. R., O'Brien, R. J., Selnes, O. A., Albert, M. S., Rodzon, B., Gottesman, R., Sacktor, N., McKhann, G. M., Turner, S., Farrington, L., Grega, M., Rudow, G., D'Agostino, D., Rudow, S., Miller, M., Mori, S. & 21 others, Ratnanather, T., Brown, T., Chi, H., Kolasny, A., Oishi, K., Reigel, T., Younes, L., Spangler, A., Scherer, R., Shade, D., Ervin, A., Jones, J., Toepfner, M., Parlett, L., Patterson, A., Mohammed, A., Lu, D., Troncoso, J., Crain, B., Pletnikova, O. & Fisher, K., Jun 1 2016, In : JAMA Neurology. 73, 6, p. 698-705 8 p.

Research output: Contribution to journalArticle

Proteomics in India: A report on a brainstorming meeting at Hyderabad, India

Chatterjee, B., Makarov, A., Clemmer, D. E., Steen, H., Steen, J., Saffell-Clemmer, W., Moghekar, A. R., Rao, C. M., Bradshaw, R. A. & Thakur, S. S., Jul 1 2016, In : Molecular and Cellular Proteomics. 15, 7, p. 2229-2235 7 p.

Research output: Contribution to journalArticle

2015

Alzheimer's disease cerebrospinal fluid biomarker in cognitively normal subjects

Toledo, J. B., Zetterberg, H., Van Harten, A. C., Glodzik, L., Martinez-Lage, P., Bocchio-Chiavetto, L., Rami, L., Hansson, O., Sperling, R., Engelborghs, S., Osorio, R. S., Vanderstichele, H., Vandijck, M., Hampel, H., Teipl, S., Moghekar, A., Albert, M., Hu, W. T., Monge Argilés, J. A., Gorostidi, A. & 12 others, Teunissen, C. E., De Deyn, P. P., Hyman, B. T., Molinuevo, J. L., Frisoni, G. B., Linazasoro, G., De Leon, M. J., Van Der Flier, W. M., Scheltens, P., Blennow, K., Shaw, L. M. & Trojanowski, J. Q., Sep 1 2015, In : Brain. 138, 9, p. 2701-2715 15 p.

Research output: Contribution to journalArticle

Changes in Aβ biomarkers and associations with APOE genotype in 2 longitudinal cohorts

Resnick, S. M., Bilgel, M., Moghekar, A., An, Y., Cai, Q., Wang, M. C., Thambisetty, M., Prince, J. L., Zhou, Y., Soldan, A., Wong, D. F., O'Brien, R. J., Ferrucci, L. & Albert, M. S., Jan 1 2015, In : Neurobiology of Aging. 36, 8, p. 2333-2339 7 p.

Research output: Contribution to journalArticle

Perioperative continuous cerebrospinal fluid pressure monitoring in patients with spontaneous cerebrospinal fluid leaks

Xie, Y. J., Shargorodsky, J., Lane, A. P., Ishii, M., Solomon, D., Moghekar, A., Gallia, G. L. & Reh, D. D., Jan 1 2015, In : International Forum of Allergy and Rhinology. 5, 1, p. 71-77 7 p.

Research output: Contribution to journalArticle

Relationship of medial temporal lobe atrophy, APOE genotype, and cognitive reserve in preclinical Alzheimer's disease

the BIOCARD Research Team, Jul 1 2015, In : Human Brain Mapping. 36, 7, p. 2826-2841 16 p.

Research output: Contribution to journalArticle

Venous sinus stenting is a valuable treatment for fulminant idiopathic intracranial hypertension

Elder, B. D., Rory Goodwin, C., Kosztowski, T. A., Radvany, M. G., Gailloud, P., Moghekar, A., Subramanian, P. S., Miller, N. R. & Rigamonti, D., Apr 1 2015, In : Journal of Clinical Neuroscience. 22, 4, p. 685-689 5 p.

Research output: Contribution to journalArticle

2014

Klotho in the cerebrospinal fluid of adults with and without Alzheimer's disease

Semba, R. D., Moghekar, A. R., Hu, J., Sun, K., Turner, R., Ferrucci, L. & O'Brien, R., Jan 13 2014, In : Neuroscience Letters. 558, p. 37-40 4 p.

Research output: Contribution to journalArticle

Neuro-ophthalmic manifestations in adult hydrocephalus

Moghekar, A. R., Jan 1 2014, In : International ophthalmology clinics. 54, 1, p. 115-121 7 p.

Research output: Contribution to journalArticle

Perceived body weight status of youngsters interferes with headache in obese and non-obese subjects: a response

Cha, N. C. I., Scher, A. I., Moghekar, A. R., Bond, D. S. & Peterlin, B. L., Jun 1 2014, In : Headache. 54, 6, p. 1063-1065 3 p.

Research output: Contribution to journalArticle