Abhai Tripathi

2023

Author Correction: mRNA-LNP expressing PfCSP and Pfs25 vaccine candidates targeting infection and transmission of Plasmodium falciparum (npj Vaccines, (2022), 7, 1, (155), 10.1038/s41541-022-00577-8)

Hayashi, C. T. H., Cao, Y., Clark, L. C., Tripathi, A. K., Zavala, F., Dwivedi, G., Knox, J., Alameh, M. G., Lin, P. J. C., Tam, Y. K., Weissman, D. & Kumar, N., Dec 2023, In: npj Vaccines. 8, 1, 115.

Research output: Contribution to journal › Comment/debate › peer-review

Open Access

Clinically relevant atovaquone-resistant human malaria parasites fail to transmit by mosquito

Balta, V. A., Stiffler, D., Sayeed, A., Tripathi, A. K., Elahi, R., Mlambo, G., Bakshi, R. P., Dziedzic, A. G., Jedlicka, A. E., Nenortas, E., Romero-Rodriguez, K., Canonizado, M. A., Mann, A., Owen, A., Sullivan, D. J., Prigge, S. T., Sinnis, P. & Shapiro, T. A., Dec 2023, In: Nature communications. 14, 1, 6415.

Research output: Contribution to journal › Article › peer-review

Open Access

Mapping the genomic landscape of multidrug resistance in Plasmodium falciparum and its impact on parasite fitness

Mok, S., Yeo, T., Hong, D., Shears, M. J., Ross, L. S., Ward, K. E., Dhingra, S. K., Kanai, M., Bridgford, J. L., Tripathi, A. K., Mlambo, G., Burkhard, A. Y., Ansbro, M. R., Fairhurst, K. J., Gil-Iturbe, E., Park, H., Rozenberg, F. D., Kim, J., Mancia, F., Fairhurst, R. M., & 4 othersQuick, M., Uhlemann, A. C., Sinnis, P. & Fidock, D. A., Nov 10 2023, In: Science Advances. 9, 45, p. eadi2364

Research output: Contribution to journal › Article › peer-review

Open Access

Novel insights into the role of long non-coding RNA in the human malaria parasite, Plasmodium falciparum

Batugedara, G., Lu, X. M., Hristov, B., Abel, S., Chahine, Z., Hollin, T., Williams, D., Wang, T., Cort, A., Lenz, T., Thompson, T. A., Prudhomme, J., Tripathi, A. K., Xu, G., Cudini, J., Dogga, S., Lawniczak, M., Noble, W. S., Sinnis, P. & Le Roch, K. G., Dec 2023, In: Nature communications. 14, 1, 5086.

Research output: Contribution to journal › Article › peer-review

Open Access

2022

A G358S mutation in the Plasmodium falciparum Na⁺ pump PfATP4 confers clinically-relevant resistance to cipargamin

Qiu, D., Pei, J. V., Rosling, J. E. O., Thathy, V., Li, D., Xue, Y., Tanner, J. D., Penington, J. S., Aw, Y. T. V., Aw, J. Y. H., Xu, G., Tripathi, A. K., Gnadig, N. F., Yeo, T., Fairhurst, K. J., Stokes, B. H., Murithi, J. M., Kümpornsin, K., Hasemer, H., Dennis, A. S. M., & 11 othersRidgway, M. C., Schmitt, E. K., Straimer, J., Papenfuss, A. T., Lee, M. C. S., Corry, B., Sinnis, P., Fidock, D. A., van Dooren, G. G., Kirk, K. & Lehane, A. M., Sep 30 2022, In: Nature communications. 13, 1, p. 5746 1 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Effective Functional Immunogenicity of a DNA Vaccine Combination Delivered via In Vivo Electroporation Targeting Malaria Infection and Transmission

Cao, Y., Hayashi, C. T. H., Zavala, F., Tripathi, A. K., Simonyan, H., Young, C. N., Clark, L. C., Usuda, Y., Van Parys, J. M. & Kumar, N., Jul 2022, In: Vaccines. 10, 7, 1134.

Research output: Contribution to journal › Article › peer-review

Open Access

mRNA-LNP expressing PfCSP and Pfs25 vaccine candidates targeting infection and transmission of Plasmodium falciparum

Hayashi, C. T. H., Cao, Y., Clark, L. C., Tripathi, A. K., Zavala, F., Dwivedi, G., Knox, J., Alameh, M. G., Lin, P. J. C., Tam, Y. K., Weissman, D. & Kumar, N., Dec 2022, In: npj Vaccines. 7, 1, 155.

Research output: Contribution to journal › Article › peer-review

Open Access

Screening the Pathogen Box for Inhibition of Plasmodium falciparum Sporozoite Motility Reveals a Critical Role for Kinases in Transmission Stages

Kanatani, S., Elahi, R., Kanchanabhogin, S., Vartak, N., Tripathi, A. K., Prigge, S. T. & Sinnis, P., Sep 2022, In: Antimicrobial agents and chemotherapy. 66, 9

Research output: Contribution to journal › Article › peer-review

2021

Immunofocusing humoral immunity potentiates the functional efficacy of the AnAPN1 malaria transmission-blocking vaccine antigen

Bender, N. G., Khare, P., Martinez, J., Tweedell, R. E., Nyasembe, V. O., López-Gutiérrez, B., Tripathi, A., Miller, D., Hamerly, T., Vela, E. M., Davis, R. R., Howard, R. F., Nsango, S., Cobb, R. R., Harbers, M. & Dinglasan, R., Dec 2021, In: npj Vaccines. 6, 1, 49.

Research output: Contribution to journal › Article › peer-review

Open Access

Plasmodium falciparum Pf77 and male development gene 1 as vaccine antigens that induce potent transmission-reducing antibodies

Tripathi, A. K., Oakley, M. S., Verma, N., Mlambo, G., Zheng, H., Meredith, S. M., Essuman, E., Puri, A., Skelton, R. A., Takeda, K., Majam, V., Quakyi, I. A., Locke, E., Morin, M., Miura, K., Long, C. A. & Kumar, S., Jun 9 2021, In: Science translational medicine. 13, 597, eabg2112.

Research output: Contribution to journal › Article › peer-review

2020

Plasmodium falciparum gametocyte culture and mosquito infection through artificial membrane feeding

Tripathi, A. K., Mlambo, G., Kanatani, S., Sinnis, P. & Dimopoulos, G., Jul 2020, In: Journal of Visualized Experiments. 2020, 161, p. 1-23 23 p., e61426.

Research output: Contribution to journal › Article › peer-review

2019

Generation of Transmission-Competent Human Malaria Parasites with Chromosomally-Integrated Fluorescent Reporters

McLean, K. J., Straimer, J., Hopp, C. S., Vega-Rodriguez, J., Small-Saunders, J. L., Kanatani, S., Tripathi, A., Mlambo, G., Dumoulin, P. C., Harris, C. T., Tong, X., Shears, M. J., Ankarklev, J., Kafsack, B. F. C., Fidock, D. A. & Sinnis, P., Dec 1 2019, In: Scientific reports. 9, 1, 13131.

Research output: Contribution to journal › Article › peer-review

Open Access

6 Scopus citations

Protein O-Fucosyltransferase 2 Is Not Essential for Plasmodium berghei Development

Sanz, S., Aquilini, E., Tweedell, R. E., Verma, G., Hamerly, T., Hritzo, B., Tripathi, A., Machado, M., Churcher, T. S., Rodrigues, J. A., Izquierdo, L. & Dinglasan, R., 2019, In: Frontiers in Cellular and Infection Microbiology. 9, p. 238 1 p.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

2018

A mosquito salivary gland protein partially inhibits Plasmodium sporozoite cell traversal and transmission

Schleicher, T. R., Yang, J., Freudzon, M., Rembisz, A., Craft, S., Hamilton, M., Graham, M., Mlambo, G., Tripathi, A. K., Li, Y., Cresswell, P., Sinnis, P., Dimopoulos, G. & Fikrig, E., Dec 1 2018, In: Nature communications. 9, 1, 2908.

Research output: Contribution to journal › Article › peer-review

Open Access

11 Scopus citations

Chromobacterium spp. mediate their anti-Plasmodium activity through secretion of the histone deacetylase inhibitor romidepsin

Saraiva, R. G., Huitt-Roehl, C. R., Tripathi, A., Cheng, Y. Q., Bosch, J., Townsend, C. A. & Dimopoulos, G., Dec 1 2018, In: Scientific reports. 8, 1, 6176.

Research output: Contribution to journal › Article › peer-review

Open Access

19 Scopus citations

Immunization with AgTRIO, a Protein in Anopheles Saliva, Contributes to Protection against Plasmodium Infection in Mice

Dragovic, S. M., Agunbiade, T. A., Freudzon, M., Yang, J., Hastings, A. K., Schleicher, T. R., Zhou, X., Craft, S., Chuang, Y. M., Gonzalez, F., Li, Y., Hrebikova, G., Tripathi, A., Mlambo, G., Almeras, L., Ploss, A., Dimopoulos, G. & Fikrig, E., Apr 11 2018, In: Cell Host and Microbe. 23, 4, p. 523-535.e5

Research output: Contribution to journal › Article › peer-review

Open Access

11 Scopus citations

Long-acting injectable atovaquone nanomedicines for malaria prophylaxis

Bakshi, R. P., Tatham, L. M., Savage, A. C., Tripathi, A. K., Mlambo, G., Ippolito, M. M., Nenortas, E., Rannard, S. P., Owen, A. & Shapiro, T. A., Dec 1 2018, In: Nature communications. 9, 1, 315.

Research output: Contribution to journal › Article › peer-review

Open Access

31 Scopus citations

Transcriptome analysis based detection of Plasmodium falciparum development in Anopheles stephensi mosquitoes

Oakley, M. S., Verma, N., Myers, T. G., Zheng, H., Locke, E., Morin, M. J., Tripathi, A. K., Mlambo, G. & Kumar, S., Dec 1 2018, In: Scientific reports. 8, 1, 11568.

Research output: Contribution to journal › Article › peer-review

Open Access

3 Scopus citations

2017

A no film slot blot for the detection of developing P. Falciparum oocysts in mosquitoes

Grabias, B., Verma, N., Zheng, H., Tripathi, A. K., Mlambo, G., Morin, M. J., Locke, E. & Kumar, S., Apr 2017, In: PloS one. 12, 4, 0174229.

Research output: Contribution to journal › Article › peer-review

Open Access

A novel gametocyte biomarker for superior molecular detection of the plasmodium falciparum infectious reservoirs

Essuman, E., Grabias, B., Verma, N., Chorazeczewski, J. K., Tripathi, A. K., Mlambo, G., Addison, E. A., Amoah, A. G. B., Quakyi, I., Oakley, M. S. & Kumar, S., Nov 15 2017, In: Journal of Infectious Diseases. 216, 10, p. 1264-1272 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

8 Scopus citations

Erratum: Plasmodium falciparum CRK4 directs continuous rounds of DNA replication during schizogony

Ganter, M., Goldberg, J. M., Dvorin, J. D., Paulo, J. A., King, J. G., Tripathi, A. K., Paul, A. S., Yang, J., Coppens, I., Jiang, R. H. Y., Elsworth, B., Baker, D. A., Dinglasan, R. R., Gygi, S. P. & Duraisingh, M. T., Mar 6 2017, In: Nature microbiology. 2, p. 17038 1 p.

Research output: Contribution to journal › Comment/debate › peer-review

Open Access

Immune regulation of plasmodium is anopheles species specific and infection intensity dependent

Simões, M. L., Mlambo, G., Tripathi, A., Dong, Y. & Dimopoulos, G., Sep 1 2017, In: mBio. 8, 5, e01631-17.

Research output: Contribution to journal › Article › peer-review

Open Access

14 Scopus citations

Plasmodium falciparum CRK4 directs continuous rounds of DNA replication during schizogony

Ganter, M., Goldberg, J. M., Dvorin, J. D., Paulo, J. A., King, J. G., Tripathi, A. K., Paul, A. S., Yang, J., Coppens, I., Jiang, R. H. Y., Elsworth, B., Baker, D. A., Dinglasan, R. R., Gygi, S. P. & Duraisingh, M. T., Feb 17 2017, In: Nature microbiology. 2, 17017.

Research output: Contribution to journal › Article › peer-review

Open Access

35 Scopus citations

2016

Molecular markers of radiation induced attenuation in intrahepatic plasmodium falciparum parasites

Oakley, M. S., Verma, N., Zheng, H., Anantharaman, V., Takeda, K., Gao, Y., Myers, T. G., Pham, P. T., Mahajan, B., Kumar, N., Sangweme, D., Tripathi, A. K., Mlambo, G., Aravind, L. & Kumar, S., Dec 2016, In: PloS one. 11, 12, e0166814.

Research output: Contribution to journal › Article › peer-review

Open Access

9 Scopus citations

Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond

Van Voorhis, W. C., Adams, J. H., Adelfio, R., Ahyong, V., Akabas, M. H., Alano, P., Alday, A., Alemán Resto, Y., Alsibaee, A., Alzualde, A., Andrews, K. T., Avery, S. V., Avery, V. M., Ayong, L., Baker, M., Baker, S., Ben Mamoun, C., Bhatia, S., Bickle, Q., Bounaadja, L., & 167 othersBowling, T., Bosch, J., Boucher, L. E., Boyom, F. F., Brea, J., Brennan, M., Burton, A., Caffrey, C. R., Camarda, G., Carrasquilla, M., Carter, D., Belen Cassera, M., Chih-Chien Cheng, K., Chindaudomsate, W., Chubb, A., Colon, B. L., Colón-López, D. D., Corbett, Y., Crowther, G. J., Cowan, N., D’Alessandro, S., Le Dang, N., Delves, M., DeRisi, J. L., Du, A. Y., Duffy, S., Abd El-Salam El-Sayed, S., Ferdig, M. T., Fernández Robledo, J. A., Fidock, D. A., Florent, I., Fokou, P. V. T., Galstian, A., Gamo, F. J., Gokool, S., Gold, B., Golub, T., Goldgof, G. M., Guha, R., Guiguemde, W. A., Gural, N., Guy, R. K., Hansen, M. A. E., Hanson, K. K., Hemphill, A., Hooft van Huijsduijnen, R., Horii, T., Horrocks, P., Hughes, T. B., Huston, C., Igarashi, I., Ingram-Sieber, K., Itoe, M. A., Jadhav, A., Naranuntarat Jensen, A., Jensen, L. T., Jiang, R. H. Y., Kaiser, A., Keiser, J., Ketas, T., Kicka, S., Kim, S., Kirk, K., Kumar, V. P., Kyle, D. E., Lafuente, M. J., Landfear, S., Lee, N., Lee, S., Lehane, A. M., Li, F., Little, D., Liu, L., Llinás, M., Loza, M. I., Lubar, A., Lucantoni, L., Lucet, I., Maes, L., Mancama, D., Mansour, N. R., March, S., McGowan, S., Medina Vera, I., Meister, S., Mercer, L., Mestres, J., Mfopa, A. N., Misra, R. N., Moon, S., Moore, J. P., Morais Rodrigues da Costa, F., Müller, J., Muriana, A., Nakazawa Hewitt, S., Nare, B., Nathan, C., Narraidoo, N., Nawaratna, S., Ojo, K. K., Ortiz, D., Panic, G., Papadatos, G., Parapini, S., Patra, K., Pham, N., Prats, S., Plouffe, D. M., Poulsen, S. A., Pradhan, A., Quevedo, C., Quinn, R. J., Rice, C. A., Rizk, M. A., Ruecker, A., St. Onge, R., Salgado Ferreira, R., Samra, J., Robinett, N. G., Schlecht, U., Schmitt, M., Silva Villela, F., Silvestrini, F., Sinden, R., Smith, D. A., Soldati, T., Spitzmüller, A., Stamm, S. M., Sullivan, D. J., Sullivan, W., Suresh, S., Suzuki, B. M., Suzuki, Y., Swamidass, S. J., Taramelli, D., Tchokouaha, L. R. Y., Theron, A., Thomas, D., Tonissen, K. F., Townson, S., Tripathi, A. K., Trofimov, V., Udenze, K. O., Ullah, I., Vallieres, C., Vigil, E., Vinetz, J. M., Voong Vinh, P., Vu, H., Watanabe, N. A., Weatherby, K., White, P. M., Wilks, A. F., Winzeler, E. A., Wojcik, E., Wree, M., Wu, W., Yokoyama, N., Zollo, P. H. A., Abla, N., Blasco, B., Burrows, J., Laleu, B., Leroy, D., Spangenberg, T., Wells, T. & Willis, P. A., Jul 2016, In: PLoS pathogens. 12, 7, e1005763.

Research output: Contribution to journal › Article › peer-review

Open Access

136 Scopus citations

2015

Antimalarial chemotherapy: Orally curative artemisinin-derived trioxane dimer esters

Conyers, R. C., Mazzone, J. R., Tripathi, A. K., Sullivan, D. J. & Posner, G. H., Jan 15 2015, In: Bioorganic and Medicinal Chemistry Letters. 25, 2, p. 245-248 4 p.

Research output: Contribution to journal › Article › peer-review

11 Scopus citations

Antimalarial iron chelator FBS0701 blocks transmission by Plasmodium falciparum gametocyte activation inhibition

Ferrer, P., Vega-Rodriguez, J., Tripathi, A. K., Jacobs-Lorena, M. & Sullivan, D. J., Mar 1 2015, In: Antimicrobial agents and chemotherapy. 59, 3, p. 1418-1426 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

16 Scopus citations

A sensitive enhanced chemiluminescent-ELISA for the detection of Plasmodium falciparum circumsporozoite antigen in midguts of Anopheles stephensi mosquitoes

Grabias, B., Zheng, H., Mlambo, G., Tripathi, A. K. & Kumar, S., Jan 1 2015, In: Journal of Microbiological Methods. 108, p. 19-24 6 p.

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Isoprenoid precursor biosynthesis is the essential metabolic role of the apicoplast during gametocytogenesis in Plasmodium falciparum

Wiley, J. D., Merino, E. F., Krai, P. M., McLean, K. J., Tripathi, A. K., Vega-Rodríguez, J., Jacobs-Lorena, M., Klemba, M. & Cassera, M. B., 2015, In: Eukaryotic Cell. 14, 2, p. 128-139 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

24 Scopus citations

2014

Antimalarial chemotherapy: Artemisinin-derived dimer carbonates and thiocarbonates

Mazzone, J. R., Conyers, R. C., Tripathi, A. K., Sullivan, D. J. & Posner, G. H., Jun 1 2014, In: Bioorganic and Medicinal Chemistry Letters. 24, 11, p. 2440-2443 4 p.

Research output: Contribution to journal › Article › peer-review

15 Scopus citations

Chromobacterium Csp_P Reduces Malaria and Dengue Infection in Vector Mosquitoes and Has Entomopathogenic and In Vitro Anti-pathogen Activities

Ramirez, J. L., Short, S. M., Bahia, A. C., Saraiva, R. G., Dong, Y., Kang, S., Tripathi, A., Mlambo, G. & Dimopoulos, G., Oct 1 2014, In: PLoS pathogens. 10, 10

Research output: Contribution to journal › Article › peer-review

Open Access

128 Scopus citations

Exploring Anopheles gut bacteria for Plasmodium blocking activity

Bahia, A. C., Dong, Y., Blumberg, B. J., Mlambo, G., Tripathi, A., Benmarzouk-Hidalgo, O. J., Chandra, R. & Dimopoulos, G., Sep 2014, In: Environmental Microbiology. 16, 9, p. 2980-2994 15 p.

Research output: Contribution to journal › Article › peer-review

Open Access

77 Scopus citations

Gametocytocidal screen identifies novel chemical classes with Plasmodium falciparum transmission blocking activity

Sanders, N. G., Sullivan, D. J., Mlambo, G., Dimopoulos, G. & Tripathi, A. K., Aug 26 2014, In: PloS one. 9, 8, e105817.

Research output: Contribution to journal › Article › peer-review

Open Access

37 Scopus citations

In vitro and in vivo antimalarial activity of amphiphilic naphthothiazolium salts with amine-bearing side chains

Ulrich, P., Gipson, G. R., Clark, M. A., Tripathi, A., Sullivan, D. J. & Cerami, C., Oct 1 2014, In: American Journal of Tropical Medicine and Hygiene. 91, 4, p. 824-832 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

Sex-partitioning of the Plasmodium falciparum stage V gametocyte proteome provides insight into falciparum-specific cell biology

Tao, D., Ubaida-Mohien, C., Mathias, D. K., King, J. G., Pastrana-Mena, R., Tripathi, A., Goldowitz, I., Graham, D. R., Moss, E., Marti, M. & Dinglasan, R. R., Oct 1 2014, In: Molecular and Cellular Proteomics. 13, 10, p. 2705-2724 20 p.

Research output: Contribution to journal › Article › peer-review

Open Access

44 Scopus citations

The survival times of malaria-infected mice are prolonged more by several new two-carbon-linked artemisinin-derived dimer carbamates than by the trioxane antimalarial drug artemether

Conyers, R. C., Mazzone, J. R., Siegler, M. A., Tripathi, A. K., Sullivan, D. J., Mott, B. T. & Posner, G. H., Mar 1 2014, In: Bioorganic and Medicinal Chemistry Letters. 24, 5, p. 1285-1289 5 p.

Research output: Contribution to journal › Article › peer-review

12 Scopus citations

2013

Model system to define pharmacokinetic requirements for antimalarial drug efficacy

Bakshi, R. P., Nenortas, E., Tripathi, A. K., Sullivan, D. J. & Shapiro, T. A., Oct 2 2013, In: Science translational medicine. 5, 205, 205ra135.

Research output: Contribution to journal › Article › peer-review

19 Scopus citations

Synthesis and antimalarial efficacy of two-carbon-linked, artemisinin-derived trioxane dimers in combination with known antimalarial drugs

Mott, B. T., Tripathi, A., Siegler, M. A., Moore, C. D., Sullivan, D. J. & Posner, G. H., Mar 28 2013, In: Journal of medicinal chemistry. 56, 6, p. 2630-2641 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

33 Scopus citations

2012

Antimalarial iron chelator, FBS0701, shows asexual and gametocyte Plasmodium falciparum activity and single oral dose cure in a murine malaria model

Ferrer, P., Tripathi, A. K., Clark, M. A., Hand, C. C., Rienhoff, H. Y. & Sullivan, D. J., May 21 2012, In: PloS one. 7, 5, e37171.

Research output: Contribution to journal › Article › peer-review

Open Access

29 Scopus citations

A restricted subset of var genes mediates adherence of Plasmodium falciparum-infected erythrocytes to brain endothelial cells

Avril, M., Tripathi, A. K., Brazier, A. J., Andisi, C., Janes, J. H., Soma, V. L., Sullivan, D. J., Bull, P. C., Stins, M. F. & Smith, J. D., Jun 26 2012, In: Proceedings of the National Academy of Sciences of the United States of America. 109, 26, p. E1782-E1790

Research output: Contribution to journal › Article › peer-review

Open Access

124 Scopus citations

Erratum: Malaria-infected mice are completely cured by one 6 mg/kg oral dose of a new monomeric trioxane sulfide combined with mefloquine (Journal of Medicinal Chemistry (2012) 55 (291-296) DOI: 10.1021/jm201214d)

Slack, R. D., Mott, B. T., Woodard, L. E., Tripathi, A., Sullivan, D., Nenortas, E., Girdwood, S. C. T., Shapiro, T. A. & Posner, G. H., Feb 23 2012, In: Journal of medicinal chemistry. 55, 4, p. 1788 1 p.

Research output: Contribution to journal › Comment/debate › peer-review

Malaria-infected mice live until at least day 30 after a new artemisinin-derived thioacetal thiocarbonate combined with mefloquine are administered together in a single, low, oral dose

Jacobine, A. M., Mazzone, J. R., Slack, R. D., Tripathi, A. K., Sullivan, D. J. & Posner, G. H., Sep 13 2012, In: Journal of medicinal chemistry. 55, 17, p. 7892-7899 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

9 Scopus citations

Molecular modeling studies, synthesis and biological evaluation of novel plasmodium falciparum lactate dehydrogenase (pfLDH) inhibitors

Ambre, P. K., Pissurlenkar, R. R. S., Jagyasi, A. S., Fule, A., Khedkar, V., Barhate, C. R., Vivas, L., Tripathi, A. K., Sullivan, D., Birkinshaw, R., Brady, R. L., Iyer, K. & Coutinho, E. C., 2012, In: Anti-Infective Agents. 10, 1, p. 55-71 17 p.

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

2011

A single, low, oral dose of a 5-carbon-linked trioxane dimer orthoester plus mefloquine cures malaria-infected mice

Moon, D. K., Tripathi, A., Sullivan, D., Siegler, M. A., Parkin, S. & Posner, G. H., May 1 2011, In: Bioorganic and Medicinal Chemistry Letters. 21, 9, p. 2773-2775 3 p.

Research output: Contribution to journal › Article › peer-review

17 Scopus citations

2010

Chemical genetics of Plasmodium falciparum

Guiguemde, W. A., Shelat, A. A., Bouck, D., Duffy, S., Crowther, G. J., Davis, P. H., Smithson, D. C., Connelly, M., Clark, J., Zhu, F., Jiménez-Díaz, M. B., Martinez, M. S., Wilson, E. B., Tripathi, A. K., Gut, J., Sharlow, E. R., Bathurst, I., Mazouni, F. E., Fowble, J. W., Forquer, I., & 15 othersMcGinley, P. L., Castro, S., Angulo-Barturen, I., Ferrer, S., Rosenthal, P. J., Derisi, J. L., Sullivan, D. J., Lazo, J. S., Roos, D. S., Riscoe, M. K., Phillips, M. A., Rathod, P. K., Van Voorhis, W. C., Avery, V. M. & Guy, R. K., May 20 2010, In: Nature. 465, 7296, p. 311-315 5 p.

Research output: Contribution to journal › Article › peer-review

Open Access

424 Scopus citations

2009

Analysis of quaternary structure of a [LDH-like] malate dehydrogenase of Plasmodium falciparum with oligomeric mutants

Pradhan, A., Mukherjee, P., Tripathi, A. K., Avery, M. A., Walker, L. A. & Tekwani, B. L., 2009, In: Molecular and Cellular Biochemistry. 325, 1-2, p. 141-148 8 p.

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Plasmodium falciparum-infected erythrocytes induce NF-κB regulated inflammatory pathways in human cerebral endothelium

Tripathi, A. K., Sha, W., Shulaev, V., Stins, M. F. & Sullivan, D. J., Nov 5 2009, In: Blood. 114, 19, p. 4243-4252 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

96 Scopus citations

Structure and function of Plasmodium falciparum malate dehydrogenase: Role of critical amino acids in co-substrate binding pocket

Pradhan, A., Tripathi, A. K., Desai, P. V., Mukherjee, P. K., Avery, M. A., Walker, L. A. & Tekwani, B. L., Nov 2009, In: Biochimie. 91, 11-12, p. 1509-1517 9 p.

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

2008

Platelet Factor 4 Mediates Inflammation in Experimental Cerebral Malaria

Srivastava, K., Cockburn, I. A., Swaim, A. M., Thompson, L. E., Tripathi, A., Fletcher, C. A., Shirk, E. M., Sun, H., Kowalska, M. A., Fox-Talbot, K., Sullivan, D., Zavala, F. & Morrell, C. N., Aug 14 2008, In: Cell Host and Microbe. 4, 2, p. 179-187 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

103 Scopus citations

2007

Plasmodium falciparum-infected erythrocytes decrease the integrity of human blood-brain barrier endothelial cell monolayers

Tripathi, A. K., Sullivan, D. J. & Stins, M. F., Apr 1 2007, In: Journal of Infectious Diseases. 195, 7, p. 942-950 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

78 Scopus citations

Abhai Tripathi

Research output

Search results