Kennedy Krieger Institute

Research Output 1963 2020

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Article
2016

A dual-learning paradigm can simultaneously train multiple characteristics of walking

Statton, M. A., Toliver, A. & Bastian, A. J., May 1 2016, In : Journal of Neurophysiology. 115, 5, p. 2692-2700 9 p.

Research output: Contribution to journalArticle

Walking
Learning
Joints
Sensory Feedback
Gait

A framework of care in multiple sclerosis, part 1: Updated disease classification and disease-modifying therapy use in specific circumstances

Newsome, S., Aliotta, P. J., Bainbridge, J., Bennett, S. E., Cutter, G., Fenton, K., Lublin, F., Northrop, D., Rintell, D., Walker, B. D., Weigel, M., Zackowski, K. & Jones, D. E., 2016, In : International Journal of MS Care. 18, 6, p. 314-323 10 p.

Research output: Contribution to journalArticle

Multiple Sclerosis
Therapeutics
Practice Guidelines
Health Personnel
Magnetic Resonance Imaging

Age-related forgetting in locomotor adaptation

Malone, L. A. & Bastian, A. J., Feb 1 2016, In : Neurobiology of Learning and Memory. 128, p. 1-6 6 p.

Research output: Contribution to journalArticle

Walking
Learning
Aptitude

Altered cholesterol biosynthesis causes precocious neurogenesis in the developing mouse forebrain

Driver, A. M., Kratz, L., Kelley, R. I. & Stottmann, R. W., Jul 1 2016, In : Neurobiology of Disease. 91, p. 69-82 14 p.

Research output: Contribution to journalArticle

Neurogenesis
Prosencephalon
Cholesterol
17-Hydroxysteroid Dehydrogenases
Embryonic Structures

A model-based approach to assess the exposure-response relationship of Lorenzo's oil in adrenoleukodystrophy

Ahmed, M. A., Kartha, R. V., Brundage, R. C., Cloyd, J., Basu, C., Carlin, B. P., Jones, R. O., Moser, A. B., Fatemi, A. & Raymond, G. V., 2016, (Accepted/In press) In : British Journal of Clinical Pharmacology.

Research output: Contribution to journalArticle

Adrenoleukodystrophy
Erucic Acids
Fatty Acids
Peroxisomal Disorders
Brain

A monoclonal antibody against KCNK9 K+ channel extracellular domain inhibits tumour growth and metastasis

Sun, H., Luo, L., Lal, B., Ma, X., Chen, L., Hann, C., Fulton, A. M., Leahy, D. J., Laterra, J. J. & Li, M., Feb 4 2016, In : Nature Communications. 7, 10339.

Research output: Contribution to journalArticle

metastasis
antibodies
Tumors
tumors
cancer

Analysis of differential gene expression mediated by clozapine in human postmortem brains

Lee, B. J., Marchionni, L., Andrews, C. E., Norris, A. L., Nucifora, L., Wu, Y. C., Wright, R. A., Pevsner, J. A., Ross, C. A., Margolis, R. L., Sawa, A. & Nucifora, F., Oct 28 2016, (Accepted/In press) In : Schizophrenia Research.

Research output: Contribution to journalArticle

Clozapine
Antipsychotic Agents
Gene Expression
Brain
Schizophrenia

Anomalous Putamen Volume in Children With Complex Motor Stereotypies

Mahone, E. M., Crocetti, D., Tochen, L., Kline, T., Mostofsky, S. H. & Singer, H., May 20 2016, (Accepted/In press) In : Pediatric Neurology.

Research output: Contribution to journalArticle

Putamen
Corpus Striatum
Caudate Nucleus
Nucleus Accumbens
Frontal Lobe

A prospective study of cerebral, frontal lobe, and temporal lobe volumes and neuropsychological performance in children with primary brain tumors treated with cranial radiation

Agbahiwe, H., Rashid, A., Horska, A., Mahone, E. M., Lin, D., McNutt, T., Cohen, K. J., Redmond, K. A., Wharam, M. & Terezakis, S. A., 2016, (Accepted/In press) In : Cancer.

Research output: Contribution to journalArticle

Frontal Lobe
Temporal Lobe
Brain Neoplasms
Radiotherapy
Prospective Studies

A specific mutation in TBL1XR1 causes Pierpont syndrome

Heinen, C. A., Jongejan, A., Watson, P. J., Redeker, B., Boelen, A., Boudzovitch-Surovtseva, O., Forzano, F., Hordijk, R., Kelley, R., Olney, A. H., Pierpont, M. E., Schaefer, G. B., Stewart, F., van Trotsenburg, A. S. P., Fliers, E., Schwabe, J. W. R. & Hennekam, R. C., Jan 14 2016, (Accepted/In press) In : Journal of Medical Genetics.

Research output: Contribution to journalArticle

Autistic Disorder
Mutation
Messenger RNA
Lymphocytes
Transducin

Assessment and treatment of anxiety in youth with Autism spectrum disorders

Vasa, R. A., Mazurek, M. O., Mahajan, R., Bennett, A. E., Bernal, M. P., Nozzolillo, A. A., Arnold, L. E. & Coury, D. L., Feb 1 2016, In : Pediatrics. 137, p. S115-S123

Research output: Contribution to journalArticle

Anxiety
Autistic Disorder
Therapeutics
Autism Spectrum Disorder
Primary Health Care

Association between a single general anesthesia exposure before age 36 months and neurocognitive outcomes in later childhood

Sun, L. S., Li, G., Miller, T. L. K., Salorio, C. F., Byrne, M. W., Bellinger, D. C., Ing, C., Park, R., Radcliffe, J., Hays, S. R., DiMaggio, C. J., Cooper, T. J., Rauh, V., Maxwell, L. G., Youn, A. & McGowan, F. X., Jun 7 2016, In : JAMA - Journal of the American Medical Association. 315, 21, p. 2312-2320 9 p.

Research output: Contribution to journalArticle

General Anesthesia
Siblings
Anesthesia
Anesthetics
Cohort Studies

Association of health professional leadership behaviors on health promotion practice beliefs

Stone, J. D., Belcher, H. M. E., Attoh, P., D'Abundo, M. & Gong, T., May 11 2016, (Accepted/In press) In : Disability and Health Journal.

Research output: Contribution to journalArticle

Health Promotion
Health
Disabled Persons
Professional Practice
Licensure

Associations among treatment-related neurological risk factors and neuropsychological functioning in survivors of childhood brain tumor

McCurdy, M. D., Rane, S., Daly, B. P. & Jacobson, L. A., Mar 1 2016, In : Journal of Neuro-Oncology. 127, 1, p. 137-144 8 p.

Research output: Contribution to journalArticle

Brain Neoplasms
Survivors
Short-Term Memory
Caregivers
Morbidity

Atypical lateralization of motor circuit functional connectivity in children with autism is associated with motor deficits

Floris, D. L., Barber, A. D., Nebel, M. B., Martinelli, M., Lai, M. C., Crocetti, D., Baron-Cohen, S., Suckling, J., Pekar, J. J. & Mostofsky, S. H., Jul 14 2016, In : Molecular Autism. 7, 1, 35.

Research output: Contribution to journalArticle

Autistic Disorder
Language
Neurologic Examination
Physical Examination
Fingers

Autism screening with online decision support by primary care pediatricians aided by M-CHAT/F

Sturner, R., Howard, B. J., Bergmann, P., Morrel, T., Andon, L., Marks, D., Rao, P. & Landa, R., Sep 1 2016, In : Pediatrics. 138, 3, e20153036.

Research output: Contribution to journalArticle

Autistic Disorder
Checklist
Primary Health Care
Research
Pediatricians

Autism spectrum disorder in the scope of tactile processing

Mikkelsen, M., Wodka, E. L., Mostofsky, S. H. & Puts, N., Jul 29 2016, (Accepted/In press) In : Developmental Cognitive Neuroscience.

Research output: Contribution to journalArticle

Touch
Neurobiology
Autism Spectrum Disorder
Central Nervous System
Phenotype

A verbal strength in children with Tourette syndrome? Evidence from a non-word repetition task

Dye, C. D., Walenski, M., Mostofsky, S. H. & Ullman, M. T., Sep 1 2016, In : Brain and Language. 160, p. 61-70 10 p.

Research output: Contribution to journalArticle

Tourette Syndrome
evidence
Tics
phonology
Basal Ganglia

Behavioral problems and service utilization in children with chronic illnesses referred for trauma-related mental health services

Wilcox, H., Rains, M., Belcher, H. M. E., Kassam-Adams, N., Kazak, A., Lee, R., Briggs, E. C., Bethel, T., Trunzo, C. P. & Wissow, L. S., 2016, In : Journal of Developmental and Behavioral Pediatrics. 37, 1, p. 62-70 9 p.

Research output: Contribution to journalArticle

Mental Health Services
Chronic Disease
Wounds and Injuries
Demography
Disabled Children

Behavior analytic approaches to problem behavior in intellectual disabilities

Hagopian, L. P. & Gregory, M. K., Mar 1 2016, In : Current Opinion in Psychiatry. 29, 2, p. 126-132 7 p.

Research output: Contribution to journalArticle

Intellectual Disability
Research
Meta-Analysis
Problem Behavior
Research Personnel

Benefits and risks of antiretroviral therapy for perinatal HIV prevention

Fowler, M. G., Qin, M., Fiscus, S. A., Currier, J. S., Flynn, P. M., Chipato, T., McIntyre, J., Gnanashanmugam, D., Siberry, G. K., Coletti, A. S., Taha, T. E., Klingman, K. L., Martinson, F. E., Owor, M., Violari, A., Moodley, D., Theron, G. B., Bhosale, R., Bobat, R., Chi, B. H. & 9 others, Strehlau, R., Mlay, P., Loftis, A. J., Browning, R., Fenton, T., Purdue, L., Basar, M., Shapiro, D. E. & Mofenson, L. M., Nov 3 2016, In : New England Journal of Medicine. 375, 18, p. 1726-1737 12 p.

Research output: Contribution to journalArticle

Zidovudine
Tenofovir
HIV
Therapeutics
CD4 Lymphocyte Count

Blocking trial-by-trial error correction does not interfere with motor learning in human walking

Long, A. W., Roemmich, R. T. & Bastian, A. J., May 1 2016, In : Journal of Neurophysiology. 115, 5, p. 2341-2348 8 p.

Research output: Contribution to journalArticle

Walking
Learning
Foot

BRAT1 mutations present with a spectrum of clinical severity

Srivastava, S., Olson, H. E., Cohen, J. S., Gubbels, C. S., Lincoln, S., Davis, B. T., Shahmirzadi, L., Gupta, S., Picker, J., Yu, T. W., Miller, D. T., Soul, J. S., Poretti, A. & Naidu, S., 2016, (Accepted/In press) In : American Journal of Medical Genetics, Part A.

Research output: Contribution to journalArticle

Mutation
Apraxias
Epilepsy
Microcephaly
Seizures

Case 236: Middle interhemispheric variant of holoprosencephaly

Yahyavi-Firouz-Abadi, N., Poretti, A., Idowu, O. R., Hoon, A. H., Huisman, T. A. & Izbudak, I., Dec 1 2016, In : Radiology. 281, 3, p. 969-974 6 p.

Research output: Contribution to journalArticle

Holoprosencephaly

Cellular and Molecular Imaging Using Chemical Exchange Saturation Transfer

Mcmahon, M. T. & Gilad, A. A., Jun 29 2016, (Accepted/In press) In : Topics in Magnetic Resonance Imaging.

Research output: Contribution to journalArticle

Molecular Imaging
Technology Transfer
Reporter Genes
Protons
Technology

Cerebellar gray matter differentiates children with early language delay in autism

D'Mello, A. M., Moore, D. M., Crocetti, D., Mostofsky, S. H. & Stoodley, C. J., 2016, (Accepted/In press) In : Autism Research.

Research output: Contribution to journalArticle

Language Development Disorders
Autistic Disorder
Appointments and Schedules
Observation
Gray Matter

Cerebellar Transcranial Direct Current Stimulation (ctDCS): A Novel Approach to Understanding Cerebellar Function in Health and Disease

Grimaldi, G., Argyropoulos, G. P., Bastian, A. J., Cortes, M., Davis, N. J., Edwards, D. J., Ferrucci, R., Fregni, F., Galea, J. M., Hamada, M., Manto, M., Miall, R. C., Morales-Quezada, L., Pope, P. A., Priori, A., Rothwell, J., Tomlinson, S. P. & Celnik, P. A., Feb 1 2016, In : Neuroscientist. 22, 1, p. 83-97 15 p.

Research output: Contribution to journalArticle

Cerebellum
Health
Cerebellar Nuclei
Cerebellar Cortex
Aptitude

Cerebral plasticity: Windows of opportunity in the developing brain

Ismail, F. Y., Fatemi, A. & Johnston, M. V., 2016, (Accepted/In press) In : European Journal of Paediatric Neurology.

Research output: Contribution to journalArticle

Neuronal Plasticity
Brain
Brain Diseases
Pediatrics
Central Nervous System

Cerebral reorganization after hemispherectomy: A DTI study

Meoded, A., Faria, A. V., Hartman, A. L., Jallo, G., Mori, S., Johnston, M. V., Huisman, T. A. G. M. & Andrea, P., May 1 2016, In : American Journal of Neuroradiology. 37, 5, p. 924-931 8 p.

Research output: Contribution to journalArticle

Hemispherectomy
Anisotropy
Pathology
Linear Models
Neurosurgical Procedures

CEST-MRI detects metabolite levels altered by breast cancer cell aggressiveness and chemotherapy response

Chan, K. W. Y., Jiang, L., Cheng, M., Wijnen, J. P., Liu, G., Huang, P., Van Zijl, P. C., Mcmahon, M. T. & Glunde, K., 2016, (Accepted/In press) In : NMR in Biomedicine.

Research output: Contribution to journalArticle

Chemotherapy
Metabolites
Magnetic resonance imaging
Cells
Breast Neoplasms

CEST theranostics: Label-free MR imaging of anticancer drugs

Li, Y., Chen, H., Xu, J., Yadav, N. N., Chan, K. W. Y., Luo, L., Mcmahon, M. T., Vogelstein, B., Van Zijl, P. C., Zhou, S. & Liu, G., 2016, In : Oncotarget. 7, 6, p. 6369-6378 10 p.

Research output: Contribution to journalArticle

Pharmaceutical Preparations
gemcitabine
Folic Acid Antagonists
Neoplasms
Liposomes

Chemical Exchange Saturation Transfer (CEST) Agents: Quantum Chemistry and MRI

Li, J., Feng, X., Zhu, W., Oskolkov, N., Zhou, T., Kim, B. K., Baig, N., Mcmahon, M. T. & Oldfield, E., Jan 4 2016, In : Chemistry - A European Journal. 22, 1, p. 264-271 8 p.

Research output: Contribution to journalArticle

Quantum chemistry
Magnetic resonance imaging
Contrast Media
Toxicity
Protons

Chlamydia trachomatis growth and development requires the activity of host Long-chain Acyl-CoA Synthetases (ACSLs)

Recuero-Checa, M. A., Sharma, M., Lau, C., Watkins, P. A., Gaydos, C. A. & Dean, D., Mar 18 2016, In : Scientific Reports. 6, 23148.

Research output: Contribution to journalArticle

Coenzyme A Ligases
Acyl Coenzyme A
Chlamydia trachomatis
Growth and Development
Fatty Acids

Clinical practice considerations in facioscapulohumeral muscular dystrophy Sydney, Australia, 21 September 2015

Tawil, R., Mah, J. K., Baker, S., Wagner, K. R. & Ryan, M. M., 2016, (Accepted/In press) In : Neuromuscular Disorders.

Research output: Contribution to journalArticle

Clinical trial preparedness in facioscapulohumeral muscular dystrophy: Clinical, tissue, and imaging outcome measures 29-30 May 2015, Rochester, New York

The FSHD Workshop Participants, Feb 1 2016, In : Neuromuscular Disorders. 26, 2, p. 181-186 6 p.

Research output: Contribution to journalArticle

Facioscapulohumeral Muscular Dystrophy
Electromyography
Biomarkers
Magnetic Resonance Imaging
Outcome Assessment (Health Care)

Cognitive Load Differentially Impacts Response Control in Girls and Boys with ADHD

Seymour, K. E., Mostofsky, S. H. & Rosch, K. S., Jan 1 2016, In : Journal of Abnormal Child Psychology. 44, 1, p. 141-154 14 p.

Research output: Contribution to journalArticle

Attention Deficit Disorder with Hyperactivity
Research

Copy number variants associated with 14 cases of self-injurious behavior

Shirley, M. D., Frelin, L., López, J. S., Jedlicka, A. E., Dziedzic, A., Frank-Crawford, M. A., Silverman, W. P., Hagopian, L. P. & Pevsner, J. A., Mar 1 2016, In : PLoS One. 11, 3, e0149646.

Research output: Contribution to journalArticle

Self-Injurious Behavior
Serotonin Receptors
Intellectual Disability
Transcription Factors
Genes

Cross-sectional and longitudinal growth patterns in osteogenesis imperfecta: Implications for clinical care

Germain-Lee, E. L., Brennen, F. S., Stern, D., Kantipuly, A., Melvin, P., Terkowitz, M. S. & Shapiro, J., Mar 1 2016, In : Pediatric Research. 79, 3, p. 489-495 7 p.

Research output: Contribution to journalArticle

Osteogenesis Imperfecta
Growth
Weights and Measures
Puberty
Life Style

Dataset for a case report of a homozygous PEX16 F332del mutation

Bacino, C., Chao, Y. H., Seto, E., Lotze, T., Xia, F., Jones, R. O., Moser, A. B. & Wangler, M. F., Mar 1 2016, In : Data in Brief. 6, p. 722-727 6 p.

Research output: Contribution to journalArticle

diagnostic

Decoupling of reaction time-related default mode network activity with cognitive demand

Barber, A. D., Caffo, B. S., Pekar, J. J. & Mostofsky, S. H., Mar 22 2016, (Accepted/In press) In : Brain Imaging and Behavior. p. 1-11 11 p.

Research output: Contribution to journalArticle

Reaction Time
Oxygen
Short-Term Memory

Decreased modulation of EEG oscillations in high-functioning autism during a motor control task

Ewen, J. B., Lakshmanan, B. M., Pillai, A. S., McAuliffe, D., Nettles, C., Hallett, M., Crone, N. E. & Mostofsky, S. H., May 6 2016, In : Frontiers in Human Neuroscience. 10, MAY2016, 198.

Research output: Contribution to journalArticle

Autistic Disorder
Electroencephalography
Imagery (Psychotherapy)
Autism Spectrum Disorder

Demonstration of Brain Tumor-Induced Neurovascular Uncoupling in Resting-State fMRI at Ultrahigh Field

Agarwal, S., Sair, H., Airan, R., Hua, J., Jones, C., Heo, H. Y., Olivi, A., Lindquist, M., Pekar, J. J. & Pillai, J., May 1 2016, In : Brain Connectivity. 6, 4, p. 267-272 6 p.

Research output: Contribution to journalArticle

Brain Neoplasms
Magnetic Resonance Imaging
Oxygen
Linear Models
Neoplasms

Developing a pro-regenerative biomaterial scaffold microenvironment requires T helper 2 cells

Sadtler, K., Estrellas, K., Allen, B. W., Wolf, M. T., Fan, H., Tam, A. J., Patel, C. H., Luber, B. S., Wang, H., Wagner, K. R., Powell, J. D., Housseau, F., Pardoll, D. M. & Elisseeff, J. H., Apr 15 2016, In : Science. 352, 6283, p. 366-370 5 p.

Research output: Contribution to journalArticle

Th2 Cells
Biocompatible Materials
Regeneration
Muscles
Interleukin-4

Developing imidazoles as CEST MRI pH sensors

Yang, X., Song, X., Ray, S., Li, Y., Byun, Y., Liu, G., Bhujwalla, Z. M., Pomper, M. G. & Mcmahon, M. T., Jul 1 2016, In : Contrast Media and Molecular Imaging. 11, 4, p. 304-312 9 p.

Research output: Contribution to journalArticle

Imidazoles
Magnetic Resonance Imaging
Heterocyclic Compounds
Intravenous Administration
Hydrogen

Development, behavior, and biomarker characterization of Smith-Lemli-Opitz syndrome: An update

Thurm, A., Tierney, E., Farmer, C., Albert, P., Joseph, L., Swedo, S., Bianconi, S., Bukelis, I., Wheeler, C., Sarphare, G., Lanham, D., Wassif, C. A. & Porter, F. D., Apr 5 2016, In : Journal of Neurodevelopmental Disorders. 8, 1, 12.

Research output: Contribution to journalArticle

Smith-Lemli-Opitz Syndrome
Biomarkers
Autistic Disorder
Cholesterol
Intellectual Disability

Development and validation of a streamlined autism case confirmation approach for use in epidemiologic risk factor research in prospective cohorts

Newschaffer, C. J., Schriver, E., Berrigan, L., Landa, R., Stone, W. L., Bishop, S., Burkom, D., Golden, A., Ibanez, L., Kuo, A., Lakes, K. D., Messinger, D. S., Paterson, S. & Warren, Z. E., 2016, (Accepted/In press) In : Autism Research.

Research output: Contribution to journalArticle

Epidemiologic Factors
Autistic Disorder
Research
Interviews
Sensitivity and Specificity

Diagnosis of a mild peroxisomal phenotype with next-generation sequencing

Ventura, M. J., Wheaton, D., Xu, M., Birch, D., Bowne, S. J., Sullivan, L. S., Daiger, S. P., Whitney, A. E., Jones, R. O., Moser, A. B., Chen, R. & Wangler, M. F., Dec 1 2016, In : Molecular Genetics and Metabolism Reports. 9, p. 75-78 4 p.

Research output: Contribution to journalArticle

Peroxisomal Disorders
Retinitis Pigmentosa
Phenotype
Usher Syndromes
Sensorineural Hearing Loss

Diffusion Tensor Imaging Abnormalities in the Cerebral White Matter Correlate with Sex-Dependent Neurobehavioral Deficits in Adult Mice with Neonatal Ischemia

Breu, M., Zhang, J., Porambo, M., Pletnikov, M., Goeral, K., Kakara, M., Johnston, M. V. & Fatemi, A., Mar 16 2016, (Accepted/In press) In : Developmental Neuroscience.

Research output: Contribution to journalArticle

Diffusion Tensor Imaging
Anisotropy
Ischemia
Wounds and Injuries
Cerebral Palsy

Do clinical features of Lesch-Nyhan disease correlate more closely with hypoxanthine or guanine recycling?

Schretlen, D., Callon, W., Ward, R. E., Fu, R., Ho, T., Gordon, B., Harris, J. C. O. & Jinnah, H. A., Jan 1 2016, In : Journal of Inherited Metabolic Disease. 39, 1, p. 85-91 7 p.

Research output: Contribution to journalArticle

Lesch-Nyhan Syndrome
Hypoxanthine
Guanine
Recycling
Phenotype