Kennedy Krieger Institute

Research Output 1963 2020

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2019

Free-base porphyrins as CEST MRI contrast agents with highly upfield shifted labile protons

Zhang, X., Yuan, Y., Li, S., Zeng, Q., Guo, Q., Liu, N., Yang, M., Yang, Y., Liu, M., Mcmahon, M. T. & Zhou, X., Aug 1 2019, In : Magnetic resonance in medicine. 82, 2, p. 577-585 9 p.

Research output: Contribution to journalArticle

Porphyrins
Contrast Media
Protons
Water
Neoplasm Grading

Furin-mediated intracellular self-assembly of olsalazine nanoparticles for enhanced magnetic resonance imaging and tumour therapy

Yuan, Y., Zhang, J., Qi, X., Li, S., Liu, G., Siddhanta, S., Barman, I., Song, X., McMahon, M. T. & Bulte, J. W. M., Jan 1 2019, (Accepted/In press) In : Nature Materials.

Research output: Contribution to journalArticle

Furin
Magnetic resonance
Self assembly
magnetic resonance
self assembly

High-resolution creatine mapping of mouse brain at 11.7 T using non-steady-state chemical exchange saturation transfer

Chen, L., Wei, Z., Cai, S., Li, Y., Liu, G., Lu, H., Weiss, R. G., van Zijl, P. C. M. & Xu, J., Jan 1 2019, (Accepted/In press) In : NMR in biomedicine. e4168.

Research output: Contribution to journalArticle

Brain Mapping
Creatine
Magnetization
Brain
Bovine Serum Albumin

Histologic severity of liver cirrhosis: A key factor affecting surgical outcomes of hepatocellular carcinoma in patients with portal hypertension

Dong, K. S., Liang, B. Y., Zhang, Z. Y., Zhang, E. L., Yang, G., Xia, S., Chen, X. P. & Huang, Z. Y., Jan 1 2019, In : Asian Journal of Surgery.

Research output: Contribution to journalArticle

Open Access
Portal Hypertension
Liver Cirrhosis
Hepatocellular Carcinoma
Fibrosis
Propensity Score

Hypothesis: Presymptomatic treatment of Sturge-Weber Syndrome With Aspirin and Antiepileptic Drugs May Delay Seizure Onset

National Institutes of Health Sponsor: Rare Diseases Clinical Research Network (RDCRN) Brain and Vascular Malformation Consortium (BVMC) SWS Investigator Group, Jan 1 2019, In : Pediatric Neurology. 90, p. 8-12 5 p.

Research output: Contribution to journalArticle

Sturge-Weber Syndrome
Intellectual Disability
Anticonvulsants
Aspirin
Epilepsy

Identification of the hyaluronic acid pathway as a therapeutic target for facioscapulohumeral muscular dystrophy

DeSimone, A. M., Leszyk, J., Wagner, K. & Emerson, C. P., Dec 11 2019, In : Science Advances. 5, 12, eaaw7099.

Research output: Contribution to journalArticle

Open Access
pathology
acids
etiology
skeletal muscle
biosynthesis

Improved state change estimation in dynamic functional connectivity using hidden semi-Markov models

Shappell, H., Caffo, B. S., Pekar, J. J. & Lindquist, M., May 1 2019, In : NeuroImage. 191, p. 243-257 15 p.

Research output: Contribution to journalArticle

Magnetic Resonance Imaging
Brain
Connectome
Brain Diseases
Anxiety

Increased mirror overflow movements in ADHD are associated with altered EEG alpha/beta band desynchronization

McAuliffe, D., Hirabayashi, K., Adamek, J. H., Luo, Y., Crocetti, D., Pillai, A. S., Zhao, Y., Crone, N. E., Mostofsky, S. H. & Ewen, J. B., Jan 1 2019, (Accepted/In press) In : European Journal of Neuroscience.

Research output: Contribution to journalArticle

Electroencephalography
Behavioral Symptoms
Fingers

Increased protein insolubility in brains from a subset of patients with schizophrenia

Nucifora, L., MacDonald, M. L., Lee, B. J., Peters, M., Norris, A. L., Orsburn, B. C., Yang, K., Gleason, K., Margolis, R. L., Pevsner, J. A., Tamminga, C. A., Sweet, R. A., Ross, C. A., Sawa, A. & Nucifora, F., Jan 1 2019, In : American Journal of Psychiatry. 176, 9, p. 730-743 14 p.

Research output: Contribution to journalArticle

Schizophrenia
Brain
Proteins
Ubiquitination
Mass Spectrometry

Individualized feedback to change multiple gait deficits in chronic stroke

Day, K. A., Cherry-Allen, K. M. & Bastian, A. J., Dec 23 2019, In : Journal of NeuroEngineering and Rehabilitation. 16, 1, 158.

Research output: Contribution to journalArticle

Open Access
Gait
Stroke
Walking
Sensory Feedback
Principal Component Analysis

Infant motor skill predicts later expressive language and autism spectrum disorder diagnosis

LeBarton, E. S. & Landa, R., Feb 1 2019, In : Infant Behavior and Development. 54, p. 37-47 11 p.

Research output: Contribution to journalArticle

Motor Skills
Language
Autism Spectrum Disorder
Caregivers
Research
Registries
Ambulatory Care Facilities
Cross-Sectional Studies

Investigating functional brain network integrity using a traditional and novel categorical scheme for neurodevelopmental disorders

Dajani, D. R., Burrows, C. A., Odriozola, P., Baez, A., Nebel, M. B., Mostofsky, S. H. & Uddin, L. Q., Jan 1 2019, In : NeuroImage: Clinical. 21, 101678.

Research output: Contribution to journalArticle

Attention Deficit Disorder with Hyperactivity
Brain
Executive Function
Aptitude
Neurobiology

Investigating Mental Health Crisis in Youth with Autism Spectrum Disorder

Vasa, R. A., Hagopian, L. & Kalb, L. G., Jan 1 2019, (Accepted/In press) In : Autism Research.

Research output: Contribution to journalArticle

Mental Health
Parents
Autistic Disorder
Quality of Life
Depression

Investigating the factor structure of the child behavior checklist dysregulation profile in children and adolescents with autism spectrum disorder

Keefer, A., Singh, V., Kalb, L. G., Mazefsky, C. A. & Vasa, R. A., Jan 1 2019, (Accepted/In press) In : Autism Research.

Research output: Contribution to journalArticle

Child Behavior
Checklist
Anxiety
Depression
Autistic Disorder

Investigating the impact of autocorrelation on time-varying connectivity

Honari, H., Choe, A., Pekar, J. J. & Lindquist, M., Aug 15 2019, In : NeuroImage. 197, p. 37-48 12 p.

Research output: Contribution to journalArticle

Brain
Noise
Magnetic Resonance Imaging

Lamin B receptor-related disorder is associated with a spectrum of skeletal dysplasia phenotypes

Thompson, E., Abdalla, E., Superti-Furga, A., McAlister, W., Kratz, L., Unger, S., Royer-Bertrand, B., Campos-Xavier, B., Mittaz-Crettol, L., Amin, A. K., DeSanto, C., Wilson, D. B., Douglas, G., Kozel, B. & Shinawi, M., Mar 1 2019, In : Bone. 120, p. 354-363 10 p.

Research output: Contribution to journalArticle

Exome
Phenotype
Sterols
Exons
Extremities

Learning of skilled movements via imitation in ASD

McAuliffe, D., Zhao, Y., Pillai, A. S., Ament, K., Adamek, J., Caffo, B. S., Mostofsky, S. H. & Ewen, J. B., Jan 1 2019, (Accepted/In press) In : Autism Research.

Research output: Contribution to journalArticle

Gestures
Learning
Autistic Disorder
Motor Skills
Learning Curve

Long-read single-molecule maps of the functional methylome

Sharim, H., Grunwald, A., Gabrieli, T., Michaeli, Y., Margalit, S., Torchinsky, D., Arielly, R., Nifker, G., Juhasz, M., Gularek, F., Almalvez, M., Dufault, B., Chandra, S. S., Liu, A., Bhattacharya, S., Chen, Y. W., Vilain, E., Wagner, K. R., Pevsner, J. A., Reifenberger, J. & 6 others, Lam, E. T., Hastie, A. R., Cao, H., Barseghyan, H., Weinhold, E. & Ebenstein, Y., Apr 1 2019, In : Genome Research. 29, 4, p. 646-656 11 p.

Research output: Contribution to journalArticle

Open Access
Methylation
Facioscapulohumeral Muscular Dystrophy
Genome
Workflow
Chromosome Mapping

Mentoring the mentors of students from diverse backgrounds for research.

Wyatt, G. E., Chin, D., Milburn, N., Hamilton, A., Lopez, S., Kim, A., Stone, J. D. & Belcher, H. M. E., Jan 1 2019, In : American Journal of Orthopsychiatry. 89, 3, p. 321-328 8 p.

Research output: Contribution to journalArticle

Racism
Mentors
Color Vision Defects
Students
Ego

Modifying constraint induced movement therapy for diverse populations

Whiston, N., Reidy, T. G., Naber, E., Carney, J. & Salorio, C. F., Jun 1 2019, In : Journal of Interprofessional Education and Practice. 15, p. 88-93 6 p.

Research output: Contribution to journalArticle

rehabilitation
motor function
performance
occupation
profession

Molecular imaging of deoxycytidine kinase activity using deoxycytidine-enhanced CEST MRI

Han, Z., Li, Y., Zhang, J., Liu, J., Chen, C., Van Zijl, P. C. & Liu, G., Jan 1 2019, In : Cancer Research. 79, 10, p. 2775-2783 9 p.

Research output: Contribution to journalArticle

Deoxycytidine Kinase
Deoxycytidine
Molecular Imaging
gemcitabine
Neoplasms
Dentate Gyrus
Intellectual Disability
Research Design
Kabuki syndrome
Cognitive Profile

Motor cortex inhibition and modulation in children with ADHD

Gilbert, D. L., Huddleston, D. A., Wu, S. W., Pedapati, E. V., Horn, P. S., Hirabayashi, K., Crocetti, D., Wassermann, E. M. & Mostofsky, S. H., Aug 6 2019, In : Neurology. 93, 6, p. e599-e610

Research output: Contribution to journalArticle

Motor Cortex
Attention Deficit Disorder with Hyperactivity
Motor Evoked Potentials
Transcranial Magnetic Stimulation
Neurobehavioral Manifestations

Mss51 deletion enhances muscle metabolism and glucose homeostasis in mice

Rovira Gonzalez, Y. I., Moyer, A. L., LeTexier, N. J., Bratti, A. D., Feng, S., Sun, C., Liu, T., Mula, J., Jha, P., Iyer, S. R., Lovering, R., O’Rourke, B., Noh, H. L., Suk, S., Kim, J. K., Essien Umanah, G. K. & Wagner, K. R., Sep 17 2019, In : JCI Insight. 4, 20, e122247.

Research output: Contribution to journalArticle

Open Access
Homeostasis
Glucose
Muscles
Skeletal Muscle
Myostatin

Neutrophils homing into the retina trigger pathology in early age-related macular degeneration

Ghosh, S., Padmanabhan, A., Vaidya, T., Watson, A. M., Bhutto, I. A., Hose, S., Shang, P., Stepicheva, N., Yazdankhah, M., Weiss, J., Das, M., Gopikrishna, S., Aishwarya, Yadav, N., Berger, T., Mak, T. W., Xia, S., Qian, J., Lutty, G. A., Jayagopal, A. & 6 others, Zigler, J. S., Sethu, S., Handa, J. T., Watkins, S. C., Ghosh, A. & Sinha, D., Dec 1 2019, In : Communications Biology. 2, 1, 348.

Research output: Contribution to journalArticle

Open Access
Lipocalins
Macular Degeneration
Pathology
retina
Infiltration

Noninvasive monitoring of chronic kidney disease using pH and perfusion imaging

Pavuluri, K. D., Manoli, I., Pass, A., Li, Y., Vernon, H. J., Venditti, C. P. & McMahon, M. T., Aug 14 2019, In : Science Advances. 5, 8, eaaw8357.

Research output: Contribution to journalArticle

Open Access
kidney diseases
mice
renal function
creatinine
kidneys

Non-suicidal self-injury and electroconvulsive therapy: Outcomes in adolescent and young adult populations

Rootes-Murdy, K., Carlucci, M., Tibbs, M., Wachtel, L. E., Sherman, M. F., Zandi, P. P. & Reti, I. M., May 1 2019, In : Journal of Affective Disorders. 250, p. 94-98 5 p.

Research output: Contribution to journalArticle

Electroconvulsive Therapy
Young Adult
Wounds and Injuries
Population
Borderline Personality Disorder

One-year cognitive and neurologic outcomes in survivors of paediatric extracorporeal cardiopulmonary resuscitation

for the Therapeutic Hypothermia after Paediatric Cardiac Arrest (THAPCA) Trial Investigatorss, Jan 1 2019, In : Resuscitation.

Research output: Contribution to journalArticle

Cardiopulmonary Resuscitation
Extracorporeal Membrane Oxygenation
Nervous System
Survivors
Psychological Adaptation

One-Year Survival and Neurologic Outcomes After Pediatric Open-Chest Cardiopulmonary Resuscitation

Therapeutic Hypothermia after Pediatric Cardiac Arrest Trial Investigators, Jan 1 2019, In : Annals of Thoracic Surgery.

Research output: Contribution to journalArticle

Psychological Adaptation
Cardiopulmonary Resuscitation
Nervous System
Thorax
Pediatrics

Parent versus teacher ratings on the BRIEF-preschool version in children with and without ADHD

Schneider, H., Ryan, M. & Mahone, E. M., Jan 1 2019, In : Child Neuropsychology.

Research output: Contribution to journalArticle

Attention Deficit Disorder with Hyperactivity
Executive Function
Parents
Equipment and Supplies
Short-Term Memory

Parsing Heterogeneity in Autism Spectrum Disorder and Attention-Deficit/Hyperactivity Disorder with Individual Connectome Mapping

Dajani, D. R., Burrows, C. A., Nebel, M. B., Mostofsky, S. H., Gates, K. M. & Uddin, L. Q., Nov 2019, In : Brain connectivity. 9, 9, p. 673-691 19 p.

Research output: Contribution to journalArticle

Connectome
Attention Deficit Disorder with Hyperactivity
Aptitude
Executive Function
Autism Spectrum Disorder
Contact Tracing
Pelvic Inflammatory Disease
Condoms
Community Health Nursing
Therapeutics

Pediatric out-of-hospital cardiac arrest: Time to goal target temperature and outcomes

for the THAPCA Trial Investigators, Feb 1 2019, In : Resuscitation. 135, p. 88-97 10 p.

Research output: Contribution to journalArticle

Out-of-Hospital Cardiac Arrest
Pediatric Hospitals
Hypothermia
Temperature
Survival

Performing Human Skeletal Muscle Xenografts in Immunodeficient Mice

Britson, K. A., Black, A. D., Wagner, K. R. & Lloyd, T., Sep 16 2019, In : Journal of visualized experiments : JoVE. 151

Research output: Contribution to journalArticle

Heterografts
Muscle
Skeletal Muscle
Muscles
Research Ethics Committees

Physical and Family History Variables Associated With Neurological and Cognitive Development in Sturge-Weber Syndrome

National Institute of Health Sponsor: Rare Disease Clinical Research Consortium (RDCRN) Brain and Vascular Malformation Consortium (BVMC) SWS Investigator Group, Jan 1 2019, In : Pediatric Neurology.

Research output: Contribution to journalArticle

Sturge-Weber Syndrome
Seizures
Learning Disorders
Brain
Age of Onset

Preschool Language Outcomes following Perinatal Hypoxic-Ischemic Encephalopathy in the Age of Therapeutic Hypothermia

Chin, E. M., Jayakumar, S., Ramos, E., Gerner, G., Soares, B. P., Cristofalo, E., Leppert, M. L., Allen, M. C., Parkinson, C., Johnston, M. V., Northington, F. & Burton, V. J., Jan 1 2019, In : Developmental Neuroscience.

Research output: Contribution to journalArticle

Open Access
Brain Hypoxia-Ischemia
Induced Hypothermia
Language
Language Development
Social Class

Prevalence of Anxiety or Depression Diagnosis in Deaf Adults

Kushalnagar, P., Reesman, J., Holcomb, T. & Ryan, C., Oct 1 2019, In : Journal of deaf studies and deaf education. 24, 4, p. 378-385 8 p.

Research output: Contribution to journalArticle

Open Access
Anxiety Disorders
Anxiety
Depression
anxiety
Health Personnel

Protein aggregation linked to Alzheimer's disease revealed by saturation transfer MRI

Chen, L., Wei, Z., Chan, K. W. Y., Cai, S., Liu, G., Lu, H., Wong, P. C., Van Zijl, P. C., Li, T. & Xu, J., Mar 1 2019, In : NeuroImage. 188, p. 380-390 11 p.

Research output: Contribution to journalArticle

Alzheimer Disease
Proteins
Protons
Water
Brain
Open Access
Sensory Feedback
Walking
Learning
Aptitude
Principal Component Analysis

Psychometric Validation of the Autism Impact Measure (AIM)

Houghton, R., Monz, B., Law, J. K., Loss, G., Le Scouiller, S., de Vries, F. & Willgoss, T., Jun 15 2019, In : Journal of Autism and Developmental Disorders. 49, 6, p. 2559-2570 12 p.

Research output: Contribution to journalArticle

Open Access
Autistic Disorder
Psychometrics
Caregivers
Aptitude
Interpersonal Relations

Quality of Life in Children With Sturge-Weber Syndrome

National Institutes of Health Sponsor: Rare Disease Clinical Research Consortium (RDCRN) Brain and Vascular Malformation Consortium (BVMC) SWS Investigator Group, Jan 1 2019, (Accepted/In press) In : Pediatric Neurology.

Research output: Contribution to journalArticle

Sturge-Weber Syndrome
Cognition
Quality of Life
Seizures
Pediatrics

Relationships between three and twelve month outcomes in children enrolled in the therapeutic hypothermia after pediatric cardiac arrest trials

for the Therapeutic Hypothermia after Pediatric Cardiac Arrest (THAPCA) Trial Investigators, Jan 1 2019, In : Resuscitation.

Research output: Contribution to journalArticle

Induced Hypothermia
Psychological Adaptation
Heart Arrest
Pediatrics
Out-of-Hospital Cardiac Arrest

Reliable change in pediatric brain tumor: A preliminary investigation

Duda, T. A., Ris, M. D., Yeates, K. O., Mahone, E. M., Haut, J. S. & Raghubar, K. P., Jan 1 2019, In : Child Neuropsychology.

Research output: Contribution to journalArticle

Brain Neoplasms
Pediatrics
Aptitude
Short-Term Memory
Analysis of Variance

Response control correlates of anomalous basal ganglia morphology in boys, but not girls, with attention-deficit/hyperactivity disorder

Tang, X., Seymour, K. E., Crocetti, D., Miller, M. I., Mostofsky, S. H. & Rosch, K. S., Jul 23 2019, In : Behavioural Brain Research. 367, p. 117-127 11 p.

Research output: Contribution to journalArticle

Attention Deficit Disorder with Hyperactivity
Basal Ganglia
Globus Pallidus
Putamen
Motor Cortex

Rett syndrome and CDKL5 deficiency disorder: From bench to clinic

Kadam, S. D., Sullivan, B. J., Goyal, A., Blue, M. E. & Smith-Hicks, C., Oct 2 2019, In : International journal of molecular sciences. 20, 20, 5098.

Research output: Contribution to journalArticle

Open Access
Cyclin-Dependent Kinase 5
Rett Syndrome
Cyclin-Dependent Kinases
seats
Methyl-CpG-Binding Protein 2

Schooling in survivorship: Understanding caregiver challenges when survivors return to school

Paré-Blagoev, E. J., Ruble, K., Bryant, C. & Jacobson, L. A., Apr 1 2019, In : Psycho-Oncology. 28, 4, p. 847-853 7 p.

Research output: Contribution to journalArticle

Caregivers
Survivors
Survival Rate
Communication
Interviews

Sex differences in employment and supports for adults with autism spectrum disorder

Taylor, J. L., Smith DaWalt, L., Marvin, A. R., Law, J. K. & Lipkin, P. H., Jan 1 2019, In : Autism.

Research output: Contribution to journalArticle

Sex Characteristics
Unemployment
Financial Support
Autistic Disorder
Internet
Open Access
Consciousness Disorders
Electroencephalography
Biomarkers
Pediatrics
Safety

SmartTots Outcomes Workshop 2017: Notes from a Round Table Discussion about Outcome Measures

Jackson, W. M., McCullough, A. K., Rauh, V. & Salorio, C. F., Jan 1 2019, In : Journal of Neurosurgical Anesthesiology. 31, 1, p. 115-118 4 p.

Research output: Contribution to journalArticle

Outcome Assessment (Health Care)
Anesthetics
Education
Research
Public-Private Sector Partnerships