Kennedy Krieger Institute

Research Output 1963 2018

Filter
Article
2018

Accelerating locomotor savings in learning: Compressing four training days to one

Day, K. A., Leech, K. A., Roemmich, R. T. & Bastian, A. J. Jun 1 2018 In : Journal of neurophysiology. 119, 6, p. 2100-2113 14 p.

Research output: Contribution to journalArticle

Walking
Learning
Space Simulation
Aptitude
Nervous System

Altered task-related modulation of long-range connectivity in children with autism

Pillai, A. S., McAuliffe, D., Lakshmanan, B. M., Mostofsky, S. H., Crone, N. E. & Ewen, J. B. Feb 1 2018 In : Autism Research. 11, 2, p. 245-257 13 p.

Research output: Contribution to journalArticle

Autistic Disorder
Task Performance and Analysis
Electroencephalography
Autism Spectrum Disorder
Attention Deficit Disorder with Hyperactivity
Brain
Frontal Lobe
Temporal Lobe
Parietal Lobe

Anxiety and mood disorder in children with autism spectrum disorder and ADHD

Gordon-Lipkin, E., Marvin, A. R., Law, J. K. & Lipkin, P. H. Apr 1 2018 In : Pediatrics. 141, 4, e20171377

Research output: Contribution to journalArticle

Attention Deficit Disorder with Hyperactivity
Anxiety Disorders
Mood Disorders
Autistic Disorder
Autism Spectrum Disorder

Are dopamine receptor and transporter changes in Rett syndrome reflected in Mecp2-deficient mice?

Wong, D. F., Blue, M. E., Brašić, J. R., Nandi, A., Valentine, H., Stansfield, K. H., Rousset, O., Bibat, G., Yablonski, M. E., Johnston, M. V., Gjedde, A. & Naidu, S. B. Sep 1 2018 In : Experimental Neurology. 307, p. 74-81 8 p.

Research output: Contribution to journalArticle

Rett Syndrome
Dopamine Plasma Membrane Transport Proteins
Dopamine Receptors
Positron-Emission Tomography
Autoradiography

Association of early postresuscitation hypotension with survival to discharge after targeted temperature management for pediatric out-of-hospital cardiac arrest secondary analysis of a randomized clinical trial

Topjian, A. A. , Moler, F. W. , Telford, R. , Holubkov, R. , Nadkarni, V. M. , Berg, R. A. , Dean, J. M. , Meert, K. L. , Hutchinson, J. S. , Newth, C. J. L. , Bennett, K. S. , Berger, J. T. , Pineda, J. A. , Koch, J. D. , Schleien, C. L. , Dalton, H. J. , Ofori-Amanfo, G. , Goodman, D. M. , Fink, E. L. , McQuillen, P. & 24 others Zimmerman, J. J., Thomas, N. J., Van Der Jagt, E. W., Porter, M. B., Meyer, M. T., Harrison, R., Pham, N., Schwarz, A. J., Nowak, J. E., Alten, J., Wheeler, D. S., Bhalala, U. S., Lidsky, K., Lloyd, E., Mathur, M., Shah, S., Wu, T., Theodorou, A. A., Sanders, R. C., Silverstein, F. S., Christensen, J. R., Slomine, B. S., Pemberton, V. L. & Browning, B. Feb 1 2018 In : JAMA Pediatrics. 172, 2, p. 143-153 11 p.

Research output: Contribution to journalArticle

Out-of-Hospital Cardiac Arrest
Pediatric Hospitals
Hypotension
Randomized Controlled Trials
Heart Arrest
Cranial Irradiation
Corpus Callosum
Anisotropy
Irradiation
Prospective Studies

ATAC-Seq analysis reveals a widespread decrease of chromatin accessibility in age-related macular degeneration

Wang, J., Zibetti, C., Shang, P., Sripathi, S. R., Zhang, P., Cano, M., Hoang, T., Xia, S., Ji, H., Merbs, S. L., Zack, D. J., Handa, J. T., Sinha, D., Blackshaw, S. & Qian, J. Dec 1 2018 In : Nature Communications. 9, 1, 1364

Research output: Contribution to journalArticle

Efflorescence
chromatin
degeneration
Macular Degeneration
Chromatin

Brief Report: Self-Injurious Behaviors in Preschool Children with Autism Spectrum Disorder Compared to Other Developmental Delays and Disorders

Soke, G. N., Rosenberg, S. A., Rosenberg, C. R., Vasa, R. A., Lee, L. C. & DiGuiseppi, C. Feb 10 2018 (Accepted/In press) In : Journal of Autism and Developmental Disorders. p. 1-9 9 p.

Research output: Contribution to journalArticle

Self-Injurious Behavior
Developmental Disabilities
Preschool Children
Odds Ratio
Confidence Intervals

Burden of caregiving after a child's in-hospital cardiac arrest

Meert, K., Slomine, B. S., Christensen, J. R., Telford, R., Holubkov, R., Dean, J. M. & Moler, F. W. Jun 1 2018 In : Resuscitation. 127, p. 44-50 7 p.

Research output: Contribution to journalArticle

Heart Arrest
Caregivers
Pediatrics
Induced Hypothermia
Psychological Adaptation
Preschool Children
Caregivers
Post-Concussion Syndrome
Brain Concussion
Enuresis

Correction to: Reduced Value-Driven Attentional Capture among Children with ADHD Compared to Typically Developing Control

Sali, A. W., Anderson, B. A., Yantis, S., Mostofsky, S. H. & Rosch, K. S. Apr 11 2018 (Accepted/In press) In : Journal of Abnormal Child Psychology. p. 1-2 2 p.

Research output: Contribution to journalArticle

Correlating Oxygen Delivery During Cardiopulmonary Bypass With the Neurologic Injury Biomarker Ubiquitin C-Terminal Hydrolase L1 (UCH-L1)

Magruder, J. T., Fraser, C. D., Grimm, J. C., Crawford, T. C., Beaty, C. A., Suarez-Pierre, A., Hayes, R. L., Johnston, M. V. & Baumgartner, W. A. Jan 1 2018 (Accepted/In press) In : Journal of Cardiothoracic and Vascular Anesthesia.

Research output: Contribution to journalArticle

Ubiquitin Thiolesterase
Nervous System Trauma
Cardiopulmonary Bypass
Biomarkers
Oxygen

Creating flexible motor memories in human walking

Leech, K. A., Roemmich, R. T. & Bastian, A. J. Dec 1 2018 In : Scientific Reports. 8, 1, 94

Research output: Contribution to journalArticle

Walking
Learning
Aptitude
Gait
Nervous System

Crizotinib and erlotinib inhibits growth of c-Met+/EGFRvIII+ primary human glioblastoma xenografts

Goodwin, C. R., Rath, P., Oyinlade, O., Lopez, H., Mughal, S., Xia, S., Li, Y., Kaur, H., Zhou, X., Ahmed, A. K., Ho, S., Olivi, A. & Lal, B. Aug 1 2018 In : Clinical Neurology and Neurosurgery. 171, p. 26-33 8 p.

Research output: Contribution to journalArticle

Glioblastoma
Heterografts
Growth
Epidermal Growth Factor Receptor
Neoplasms
Developmental Disabilities
Intellectual Disability
Epilepsy
Mutation

Detection and differentiation of Cys, Hcy and GSH mixtures by 19F NMR probe

Yang, S., Zeng, Q., Guo, Q., Chen, S., Liu, H., Liu, M., McMahon, M. T. & Zhou, X. Jul 1 2018 In : Talanta. 184, p. 513-519 7 p.

Research output: Contribution to journalArticle

Urea fertilizers
Nuclear magnetic resonance
Negative impedance converters
Addition reactions
Cyclization

Developmental Trajectory of Motor Deficits in Preschool Children with ADHD

Sweeney, K. L., Ryan, M., Schneider, H., Ferenc, L., Denckla, M. B. & Mark Mahone, E. May 13 2018 (Accepted/In press) In : Developmental Neuropsychology. p. 1-11 11 p.

Research output: Contribution to journalArticle

Preschool Children
Fingers
Neurologic Examination
Physical Examination
Longitudinal Studies

Early detection of hypothermic neuroprotection using T2-weighted magnetic resonance imaging in a mouse model of hypoxic ischemic encephalopathy

Doman, S. E., Girish, A., Nemeth, C. L., Drummond, G. T., Carr, P., Garcia, M. S., Johnston, M. V., Kannan, S., Fatemi, A., Zhang, J. & Wilson, M. A. May 8 2018 In : Frontiers in Neurology. 9, MAY, 304

Research output: Contribution to journalArticle

Brain Hypoxia-Ischemia
Ischemia
Magnetic Resonance Imaging
Hypothermia
Wounds and Injuries

ECT for Self-Injurious Behavior in Autism: A New Indication

Wachtel, L. E., Kellner, C. H. & Fink, M. Feb 1 2018 In : Psychiatric Times. 35, 2, p. 6-9 4 p.

Research output: Contribution to journalArticle

Self-Injurious Behavior
Autistic Disorder

Engineering functional and histological regeneration of vascularized skeletal muscle

Gilbert-Honick, J., Iyer, S. R., Somers, S. M., Lovering, R. M., Wagner, K., Mao, H. Q. & Grayson, W. L. May 1 2018 In : Biomaterials. 164, p. 70-79 10 p.

Research output: Contribution to journalArticle

Muscle
Regeneration
Skeletal Muscle
Scaffolds
Muscles

Exploring Relationships Between Negative Cognitions and Anxiety Symptoms in Youth With Autism Spectrum Disorder

Keefer, A., Kreiser, N. L., Singh, V., Blakeley-Smith, A., Reaven, J. & Vasa, R. A. Jan 1 2018 (Accepted/In press) In : Behavior Therapy.

Research output: Contribution to journalArticle

Cognition
Anxiety
Autism Spectrum Disorder
Uncertainty
Depression
Tourette Syndrome
gamma-Aminobutyric Acid
Glutamic Acid
Magnetic Resonance Spectroscopy
Motor Cortex

Global identification of Small Ubiquitin-related Modifier (SUMO) substrates reveals crosstalk between SUMOylation and phosphorylation promotes cell migration

Uzoma, I., Hu, J., Cox, E., Xia, S., Zhou, J., Rho, H. S., Guzzo, C., Paul, C., Ajala, O., Goodwin, C. R., Jeong, J., Moore, C., Zhang, H., Meluh, P., Blackshaw, S., Matunis, M., Qian, J. & Zhu, H. May 1 2018 In : Molecular and Cellular Proteomics. 17, 5, p. 871-888 18 p.

Research output: Contribution to journalArticle

Sumoylation
Ubiquitin
Cell Movement
Phosphorylation
Rotary engines

Heterozygous IDH1R132H/WT created by “single base editing” inhibits human astroglial cell growth by downregulating YAP

Wei, S., Wang, J., Oyinlade, O., Ma, D., Wang, S., Kratz, L., Lal, B., Xu, Q., Liu, S., Shah, S. R., Zhang, H., Li, Y., Quiñones-Hinojosa, A., Zhu, H., Huang, Z. Y., Cheng, L., Qian, J. & Xia, S. May 30 2018 (Accepted/In press) In : Oncogene. p. 1-15 15 p.

Research output: Contribution to journalArticle

Isocitrate Dehydrogenase
Down-Regulation
Growth
Proteins
Mutation
Self-Injurious Behavior
behavior analysis
Biomarkers
Therapeutics
physician's care

Improved estimation of subject-level functional connectivity using full and partial correlation with empirical Bayes shrinkage

Mejia, A. F., Nebel, M. B., Barber, A. D., Choe, A. S., Pekar, J. J., Caffo, B. S. & Lindquist, M. A. May 15 2018 In : NeuroImage. 172, p. 478-491 14 p.

Research output: Contribution to journalArticle

Bayes Theorem
Connectome
Research Design
Magnetic Resonance Imaging

Krüppel-like factor 4 (KLF4) induces mitochondrial fusion and increases spare respiratory capacity of human glioblastoma cells

Wang, S., Shi, X., Wei, S., Ma, D., Oyinlade, O., Lv, S. Q., Ying, M., Zhang, Y. A., Claypool, S. M., Watkins, P. & Xia, S. Jan 1 2018 In : Journal of Biological Chemistry. 293, 17, p. 6544-6555 12 p.

Research output: Contribution to journalArticle

Mitochondrial Dynamics
Glioblastoma
Metabolism
Fusion reactions
Cells
Postnatal Care
Health Behavior
Postpartum Period
Mothers
Dental Care

MeDReaders: A database for transcription factors that bind to methylated DNA

Wang, G., Luo, X., Wang, J., Wan, J., Xia, S., Zhu, H., Qian, J. & Wang, Y. Jan 1 2018 In : Nucleic acids research. 46, D1, p. D146-D151

Research output: Contribution to journalArticle

Transcription Factors
Databases
DNA
Methylation
Biological Phenomena
Molecular imaging
Molecular Imaging
Reporter Genes
Gene expression
Magnetic resonance imaging

Monogenic disorders that mimic the phenotype of Rett syndrome

Srivastava, S., Desai, S., Cohen, J., Smith-Hicks, C., Barañano, K., Fatemi, A. & Naidu, S. B. Jan 10 2018 (Accepted/In press) In : Neurogenetics. p. 1-7 7 p.

Research output: Contribution to journalArticle

Rett Syndrome
Methyl-CpG-Binding Protein 2
Phenotype
Exome
Hand

MRI detection of bacterial brain abscesses and monitoring of antibiotic treatment using bacCEST

Liu, J., Bai, R., Li, Y., Staedtke, V., Zhang, S., van Zijl, P. C. M. & Liu, G. Jan 1 2018 (Accepted/In press) In : Magnetic resonance in medicine.

Research output: Contribution to journalArticle

Brain Abscess
Anti-Bacterial Agents
Bacterial Infections
Bacteria
Therapeutics

Multivoxel proton magnetic resonance spectroscopy in facioscapulohumeral muscular dystrophy

Leung, D. G., Wang, X., Barker, P. B., Carrino, J. A. & Wagner, K. R. Jun 1 2018 In : Muscle and Nerve. 57, 6, p. 958-963 6 p.

Research output: Contribution to journalArticle

Facioscapulohumeral Muscular Dystrophy
Creatine
Muscle Strength
Muscles
Thigh

Narp Mediates Antidepressant-Like Effects of Electroconvulsive Seizures

Chang, A. D., Vaidya, P. V., Retzbach, E. P., Chung, S. J., Kim, U., Baselice, K., Maynard, K., Stepanian, A., Staley, M., Xiao, L., Blouin, A., Han, S., Lee, J., Worley, P. F., Tamashiro, K. L., Hempstead, B. L., Martinowich, K., Wilson, M. A., Baraban, J. M. & Reti, I. M. Apr 1 2018 In : Neuropsychopharmacology. 43, 5, p. 1088-1098 11 p.

Research output: Contribution to journalArticle

Antidepressive Agents
Seizures
Electroconvulsive Therapy
Neuronal Plasticity
Immediate-Early Genes

Neurobehavioural outcomes in children after In-Hospital cardiac arrest

Slomine, B. S., Silverstein, F. S., Christensen, J. R., Holubkov, R., Telford, R., Dean, J. M., Moler, F. W. & on behalf of the Therapeutic Hypothermia after Paediatric Cardiac Arrest (THAPCA) Trial Investigators Mar 1 2018 In : Resuscitation. 124, p. 80-89 10 p.

Research output: Contribution to journalArticle

Heart Arrest
Psychological Adaptation
Survivors
Pediatric Hospitals
Coma

Paediatric in-hospital cardiac arrest: Factors associated with survival and neurobehavioural outcome one year later

Meert, K., Telford, R., Holubkov, R., Slomine, B. S., Christensen, J. R., Berger, J., Ofori-Amanfo, G., Newth, C. J. L., Dean, J. M. & Moler, F. W. Mar 1 2018 In : Resuscitation. 124, p. 96-105 10 p.

Research output: Contribution to journalArticle

Pediatric Hospitals
Psychological Adaptation
Heart Arrest
Thorax
Lactic Acid

Phenols as Diamagnetic T2-Exchange Magnetic Resonance Imaging Contrast Agents

Zhang, J., Li, Y., Slania, S., Yadav, N. N., Liu, J., Wang, R., Zhang, J., Pomper, M. G., van Zijl, P. C., Yang, X. & Liu, G. Jan 26 2018 In : Chemistry - A European Journal. 24, 6, p. 1259-1263 5 p.

Research output: Contribution to journalArticle

Hole mobility
Chemical modification
Chemical shift
Enzyme activity
Magnetic resonance imaging

Predicting changes in adaptive functioning and behavioral adjustment following treatment for a pediatric brain tumor: A report from the Brain Radiation Investigative Study Consortium

Hoskinson, K. R., Wolfe, K. R., Yeates, K. O., Mahone, E. M., Cecil, K. M. & Ris, M. D. Jan 1 2018 In : Psycho-Oncology. 27, 1, p. 178-186 9 p.

Research output: Contribution to journalArticle

Social Adjustment
Brain Neoplasms
Radiation
Pediatrics
Brain
Neurologic Examination
Physical Examination
Sports
Wounds and Injuries
Social Class

Processing speed in children treated for brain tumors: effects of radiation therapy and age

Jacobson, L. A., Mahone, E. M., Yeates, K. O. & Ris, M. D. Apr 7 2018 (Accepted/In press) In : Child Neuropsychology. p. 1-15 15 p.

Research output: Contribution to journalArticle

Brain Neoplasms
Radiotherapy
Brain
Therapeutics
Brain Injuries
Psychometrics
Mental Health
Psychiatric Emergency Services
Parents
Autism Spectrum Disorder

Rapid and quantitative chemical exchange saturation transfer (CEST) imaging with magnetic resonance fingerprinting (MRF)

Cohen, O., Huang, S., Mcmahon, M. T., Rosen, M. S. & Farrar, C. T. Jan 1 2018 (Accepted/In press) In : Magnetic resonance in medicine.

Research output: Contribution to journalArticle

Protons
Magnetic Resonance Imaging
Magnetic Resonance Spectroscopy
Amides
Amines

Relationships between autism spectrum disorder and intolerance of uncertainty

Vasa, R. A., Kreiser, N. L., Keefer, A., Singh, V. & Mostofsky, S. H. Apr 1 2018 In : Autism Research. 11, 4, p. 636-644 9 p.

Research output: Contribution to journalArticle

Uncertainty
Anxiety
Emotions
Autistic Disorder
Intellectual Disability

Risk Factors for Self-injurious Behavior in an Inpatient Psychiatric Sample of Children with Autism Spectrum Disorder: A Naturalistic Observation Study

The Autism And Developmental Disorders Inpatient Research Collaborative (Addirc) Jan 24 2018 (Accepted/In press) In : Journal of Autism and Developmental Disorders. p. 1-11 11 p.

Research output: Contribution to journalArticle

Self-Injurious Behavior
Psychiatry
Inpatients
Observation
Caregivers

Salicylic Acid-Based Polymeric Contrast Agents for Molecular Magnetic Resonance Imaging of Prostate Cancer

Banerjee, S. R., Song, X., Yang, X., Minn, I., Lisok, A., Chen, Y., Bui, A., Chatterjee, S., Chen, J., vanZijl, P. C. M., Mcmahon, M. T. & Pomper, M. G. Jan 1 2018 (Accepted/In press) In : Chemistry - A European Journal.

Research output: Contribution to journalArticle

Salicylic acid
Hole mobility
Imaging techniques
Magnetic resonance
Protons

Sleep dysfunction following neonatal ischemic seizures are differential by neonatal age of insult as determined by qEEG in a mouse model

Kang, S. K., Ammanuel, S., Thodupunuri, S., Adler, D. A., Johnston, M. V. & Kadam, S. D. Aug 1 2018 In : Neurobiology of Disease. 116, p. 1-12 12 p.

Research output: Contribution to journalArticle

Sleep
Seizures
Age Groups
Brain Hypoxia-Ischemia
Phenobarbital
Motor Skills
Reading
Neurobehavioral Manifestations
Phenotype

Spondylolisthesis is Common, Early, and Severe in Loeys-Dietz Syndrome

Kirby, D. J., Dietz, H. C. & Sponseller, P. D. Jun 8 2018 (Accepted/In press) In : Journal of Pediatric Orthopaedics.

Research output: Contribution to journalArticle

Loeys-Dietz Syndrome
Spondylolisthesis
Spondylolysis
Spinal Fusion
Arthrodesis

Targeting UDP-α-d-glucose 6-dehydrogenase inhibits glioblastoma growth and migration

Oyinlade, O., Wei, S., Lal, B., Laterra, J., Zhu, H., Goodwin, C. R., Wang, S., Ma, D., Wan, J. & Xia, S. Feb 26 2018 (Accepted/In press) In : Oncogene. p. 1-15 15 p.

Research output: Contribution to journalArticle

Uridine Diphosphate Glucose Dehydrogenase
Glucose 1-Dehydrogenase
Uridine Diphosphate
Glioblastoma
Growth