Kennedy Krieger Institute

Research Output 1963 2018

2018

Chapter 3: Chemical Exchange Saturation Transfer (CEST) Contrast Agents

Ferrauto, G., Aime, S., McMahon, M. T., Morrow, J. R., Snyder, E. M., Li, A. & Bartha, R. Jan 1 2018 New Developments in NMR. 13 ed. Royal Society of Chemistry, Vol. 2018-January, p. 243-317 75 p. (New Developments in NMR; vol. 2018-January, no. 13)

Research output: ResearchChapter

Contrast Media
Protons
Water
Hole mobility
Micelles
Psychometrics
Mental Health
Autism Spectrum Disorder
Parents
Psychiatric Emergency Services
2017
Beauty
Medical Genetics

Abnormal grey matter arteriolar cerebral blood volume in schizophrenia measured with 3D inflow-based vascular-space-occupancy MRI at 7T

Hua, J., Brandt, A. S., Lee, S. W., Blair, N. I. S., Wu, Y., Lui, S., Patel, J., Faria, A. V., Lim, I. A. L., Unschuld, P. G., Pekar, J. J., Van Zijl, P. C. M., Ross, C. A. & Margolis, R. L. 2017 In : Schizophrenia Bulletin. 43, 3, p. 620-632 13 p.

Research output: Research - peer-reviewArticle

Blood Vessels
Schizophrenia
Brain
Cerebral Blood Volume
Gray Matter
Hematocrit
Hemodynamics
Cerebrovascular Circulation
Oxygen
Magnetic Resonance Imaging

Accurate Autism Screening at the 18-Month Well-Child Visit Requires Different Strategies than at 24 Months

Sturner, R., Howard, B., Bergmann, P., Morrel, T., Landa, R., Walton, K. & Marks, D. Jul 31 2017 (Accepted/In press) In : Journal of Autism and Developmental Disorders. p. 1-15 15 p.

Research output: Research - peer-reviewArticle

Autistic Disorder
Interviews
Language
Multivariate Analysis
Equipment and Supplies

A dextran-based probe for the targeted magnetic resonance imaging of tumours expressing prostate-specific membrane antigen

Liu, G., Banerjee, S. R., Yang, X., Yadav, N., Lisok, A., Jablonska, A., Xu, J., Li, Y., Pomper, M. G. & Van Zijl, P. Dec 1 2017 In : Nature Biomedical Engineering. 1, 12, p. 977-982 6 p.

Research output: Research - peer-reviewArticle

Dextran
Magnetic resonance
Antigens
Tumors
Membranes
De Lange Syndrome
Neuropsychiatry
Fetal Alcohol Spectrum Disorders
Self-Injurious Behavior
Down Syndrome

A human brain microphysiological system derived from induced pluripotent stem cells to study neurological diseases and toxicity

Pamies, D., Barreras, P., Block, K., Makri, G., Kumar, A., Wiersma, D., Smirnova, L., Zhang, C., Bressler, J., Christian, K. M., Harris, G., Ming, G. L., Berlinicke, C. J., Kyro, K., Song, H., Pardo, C. A., Hartung, T. & Hogberg, H. T. 2017 In : Altex. 34, 3, p. 362-376 15 p.

Research output: Research - peer-reviewArticle

Induced Pluripotent Stem Cells
Brain
Neuroglia
Neurons
Myelin Sheath

Altered tactile sensitivity in children with Attention-Deficit hyperactivity disorder

Puts, N. A. J., Harris, A. D., Mikkelsen, M., Tommerdahl, M., Edden, R. A. E. & Mostofsky, S. H. Nov 1 2017 In : Journal of Neurophysiology. 118, 5, p. 2568-2578 11 p.

Research output: Research - peer-reviewArticle

Touch
Attention Deficit Disorder with Hyperactivity
Inhibition (Psychology)
Reaction Time
Discrimination (Psychology)

Anomalous subcortical morphology in boys, but not girls, with ADHD compared to typically developing controls and correlates with emotion dysregulation

Seymour, K. E., Tang, X., Crocetti, D., Mostofsky, S. H., Miller, M. I. & Rosch, K. S. Mar 30 2017 In : Psychiatry Research - Neuroimaging. 261, p. 20-28 9 p.

Research output: Research - peer-reviewArticle

Emotions
Globus Pallidus
Amygdala
Putamen
Diagnostic and Statistical Manual of Mental Disorders

Antioxidant capacity and superoxide dismutase activity in adrenoleukodystrophy

Turk, B. R., Theisen, B. E., Nemeth, C. L., Marx, J. S., Shi, X., Rosen, M., Jones, R. O., Moser, A. B., Watkins, P. A., Raymond, G. V., Tiffany, C. & Fatemi, A. May 1 2017 In : JAMA Neurology. 74, 5, p. 519-524 6 p.

Research output: Research - peer-reviewArticle

Adrenoleukodystrophy
Superoxide Dismutase
Antioxidants
Heterozygote
Proteins

Aortic Root Replacement for Children With Loeys-Dietz Syndrome

Patel, N. D., Alejo, D., Crawford, T., Hibino, N., Dietz, H. C., Cameron, D. E. & Vricella, L. A. 2017 (Accepted/In press) In : Annals of Thoracic Surgery.

Research output: Research - peer-reviewArticle

Loeys-Dietz Syndrome
Aortic Valve
Prostheses and Implants
Mortality
Coronary Aneurysm

A prospective study of corpus callosum regional volumes and neurocognitive outcomes following cranial radiation for pediatric brain tumors

Rashid, A., Ram, A. N., Kates, W. R., Redmond, K. J., Wharam, M., Mark Mahone, E., Horska, A. & Terezakis, S. Apr 28 2017 (Accepted/In press) In : Child's Nervous System. p. 1-8 8 p.

Research output: Research - peer-reviewArticle

Corpus Callosum
Brain Neoplasms
Prospective Studies
Radiation
Pediatrics

Arbaclofen in fragile X syndrome: Results of phase 3 trials

Berry-Kravis, E., Hagerman, R., Visootsak, J., Budimirovic, D., Kaufmann, W. E., Cherubini, M., Zarevics, P., Walton-Bowen, K., Wang, P., Bear, M. F. & Carpenter, R. L. Jun 12 2017 In : Journal of Neurodevelopmental Disorders. 9, 1, 9

Research output: Research - peer-reviewArticle

Fragile X Syndrome
Placebos
Socialization
Psychological Adaptation
Parenting

A review of repetitive transcranial magnetic stimulation for adolescents with treatment-resistant depression

Magavi, L. R., Reti, I. M. & Vasa, R. A. Mar 4 2017 In : International Review of Psychiatry. 29, 2, p. 79-88 10 p.

Research output: Research - peer-reviewReview article

Treatment-Resistant Depressive Disorder
Transcranial Magnetic Stimulation
Therapeutics
Scalp
Seizures

Associations between Foot Placement Asymmetries and Metabolic Cost of Transport in Hemiparetic Gait

Finley, J. M. & Bastian, A. J. 2017 In : Neurorehabilitation and Neural Repair. 31, 2, p. 168-177 10 p.

Research output: Research - peer-reviewArticle

Gait
Foot
Costs and Cost Analysis
Survivors
Stroke
Waist Circumference
Intercellular Adhesion Molecule-1
Saliva
Methylation
Adipose Tissue
Cerebral Blood Volume
Photic Stimulation
Magnetic Resonance Imaging
Oxygen
Cerebrovascular Circulation

A unified Bayesian approach to extract network-based functional differences from a heterogeneous patient cohort

Venkataraman, A., Wymbs, N., Nebel, M. B. & Mostofsky, S. 2017 Connectomics in NeuroImaging - 1st International Workshop, CNI 2017 Held in Conjunction with MICCAI 2017, Proceedings. Springer Verlag, Vol. 10511 LNCS, p. 60-69 10 p. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); vol. 10511 LNCS)

Research output: ResearchConference contribution

Bayesian Approach
Model
Connectivity
Framework
EM Algorithm

Behavioral Symptoms of Reported Abuse in Children and Adolescents with Autism Spectrum Disorder in Inpatient Settings

Brenner, J. , Pan, Z. , Mazefsky, C. , Smith, K. A. , Gabriels, R. , Siegel, M. , Erickson, C. , Gabriels, R. L. , Kaplan, D. , Mazefsky, C. , Morrow, E. M. , Righi, G. , Santangelo, S. L. , Wink, L. , Benevides, J. , Beresford, C. , Best, C. , Bowen, K. , Dechant, B. , Flis, T. & 26 others Gastgeb, H., Geer, A., Hagopian, L., Handen, B., Klever, A., Lubetsky, M., MacKenzie, K., Meservy, Z., McGonigle, J., McGuire, K., McNeil, F., Pedapati, E., Peura, C., Pierri, J., Rogers, C., Rossman, B., Ruberg, J., Small, C., Smith, K. A., Stuckey, N., Tylenda, B., Verdi, M., Vezzoli, J., Williams, D., Williams, D. & For The Autism And Developmental Disorders Inpatient Research Collaborative (Addirc) Jun 7 2017 (Accepted/In press) In : Journal of Autism and Developmental Disorders. p. 1-9 9 p.

Research output: Research - peer-reviewArticle

Behavioral Symptoms
Child Abuse
Inpatients
Autism Spectrum Disorder
Post-Traumatic Stress Disorders

Behavioral Treatments for Anxiety in Minimally Verbal Children with ASD

Hagopian, L. P., Lilly, M. & Davis, T. E. Jan 4 2017 Anxiety in Children and Adolescents with Autism Spectrum Disorder: Evidence-Based Assessment and Treatment. Elsevier Inc., p. 193-210 18 p.

Research output: ResearchChapter

Anxiety
Therapeutics
Aptitude
Cognitive Therapy
Self Report

Can a Neurosteroid Ameliorate Fragile X-Associated Tremor/Ataxia Syndrome?

Budimirovic, D. B. Sep 7 2017 (Accepted/In press) In : Neurotherapeutics. p. 1-3 3 p.

Research output: Research - peer-reviewArticle

Neurotransmitter Agents
Fragile X Tremor Ataxia Syndrome

Candidate gene analysis for Alzheimer's disease in adults with Down syndrome

Lee, J. H., Lee, A. J., Dang, L. H., Pang, D., Kisselev, S., Krinsky-McHale, S. J., Zigman, W. B., Luchsinger, J. A., Silverman, W., Tycko, B., Clark, L. N. & Schupf, N. Aug 1 2017 In : Neurobiology of Aging. 56, p. 150-158 9 p.

Research output: Research - peer-reviewArticle

Genetic Association Studies
Down Syndrome
Alzheimer Disease
Genes
Single Nucleotide Polymorphism

Candidate gene resequencing in a large bicuspid aortic valve-associated thoracic aortic aneurysm cohort: SMAD6 as an important contributor

Gillis, E. , Kumar, A. A. , Luyckx, I. , Preuss, C. , Cannaerts, E. , Beek, G. V. D. , Wieschendorf, B. , Alaerts, M. , Bolar, N. , Vandeweyer, G. , Meester, J. , Wünnemann, F. , Gould, R. A. , Zhurayev, R. , Zerbino, D. , Mohamed, S. A. , Mital, S. , Mertens, L. , Björck, H. M. , Franco-Cereceda, A. & 20 others McCallion, A. S., Van Laer, L., Verhagen, J. M. A., van de Laar, I. M. B. H., Wessels, M. W., Messas, E., Goudot, G., Nemcikova, M., Krebsova, A., Kempers, M., Salemink, S., Duijnhouwer, T., Jeunemaitre, X., Albuisson, J., Eriksson, P., Andelfinger, G., Dietz, H. C., Verstraeten, A., Loeys, B. L. & Mibava Leducq Consortium Jun 13 2017 In : Frontiers in Physiology. 8, JUN, 400

Research output: Research - peer-reviewArticle

Thoracic Aortic Aneurysm
Genes
Bicuspid Aortic Valve
Exome
Frameshift Mutation

Cannabidiol Treatment for Refractory Seizures in Sturge-Weber Syndrome

Kaplan, E. H., Offermann, E. A., Sievers, J. W. & Comi, A. M. Jun 1 2017 In : Pediatric Neurology. 71, p. 18-23.e2

Research output: Research - peer-reviewArticle

Cannabidiol
Sturge-Weber Syndrome
Seizures
Epilepsy
Quality of Life

Cardiovascular operations for Loeys-Dietz syndrome: Intermediate-term results

Patel, N. D., Crawford, T., Magruder, J. T., Alejo, D. E., Hibino, N., Black, J., Dietz, H. C., Vricella, L. A. & Cameron, D. E. Feb 1 2017 In : Journal of Thoracic and Cardiovascular Surgery. 153, 2, p. 406-412 7 p.

Research output: Research - peer-reviewArticle

Loeys-Dietz Syndrome
Dissection
Aneurysm
Sternotomy
Aortic Aneurysm

Characterization of Medication Use in a Multicenter Sample of Pediatric Inpatients with Autism Spectrum Disorder

Wink, L. K. , Pedapati, E. V. , Adams, R. , Erickson, C. A. , Pedersen, K. A. , Morrow, E. M. , Kaplan, D. , Siegel, M. , Siegel, M. , Erickson, C. , Gabriels, R. L. , Kaplan, D. , Mazefsky, C. , Morrow, E. M. , Righi, G. , Santangelo, S. L. , Wink, L. , Benevides, J. , Beresford, C. , Best, C. & 41 others Bowen, K., Dechant, B., Flis, T., Gastgeb, H., Geer, A., Hagopian, L., Handen, B., Klever, A., Lubetsky, M., MacKenzie, K., Meservy, Z., McGonigle, J., McGuire, K., McNeil, F., Montrenes, J., Palka, T., Pedapati, E., Pedersen, K. A., Peura, C., Pierri, J., Rogers, C., Rossman, B., Ruberg, J., Sannar, E., Small, C., Stuckey, N., Tylenda, B., Verdi, M., Vezzoli, J., Williams, D., Williams, D., Germain, D. L. S., Robinson, G., Kasari, C., King, B., McCracken, J., McDougle, C., Scahill, L., Schultz, R., Tager-Flusberg, H. & For The Autism And Developmental Disorders Inpatient Research Collaborative (Addirc) May 17 2017 (Accepted/In press) In : Journal of Autism and Developmental Disorders. p. 1-9 9 p.

Research output: Research - peer-reviewArticle

Inpatients
Pediatrics
Autism Spectrum Disorder
Autistic Disorder
Antipsychotic Agents

Characterization of tumor vascular permeability using natural dextrans and CEST MRI

Li, Y., Qiao, Y., Chen, H., Bai, R., Staedtke, V., Han, Z., Xu, J., Chan, K. W. Y., Yadav, N., Bulte, J. W. M., Zhou, S., van Zijl, P. C. M. & Liu, G. Jan 1 2017 (Accepted/In press) In : Magnetic Resonance in Medicine.

Research output: Research - peer-reviewArticle

Capillary Permeability
Dextrans
Neoplasms
Injections
Permeability

Chronobiology of Acute Aortic Dissection in the Marfan Syndrome (from the National Registry of Genetically Triggered Thoracic Aortic Aneurysms and Cardiovascular Conditions and the International Registry of Acute Aortic Dissection)

Siddiqi, H. K., Luminais, S. N., Montgomery, D., Bossone, E., Dietz, H., Evangelista, A., Isselbacher, E., LeMaire, S., Manfredini, R., Milewicz, D., Nienaber, C. A., Roman, M., Sechtem, U., Silberbach, M., Eagle, K. A. & Pyeritz, R. E. Mar 1 2017 In : American Journal of Cardiology. 119, 5, p. 785-789 5 p.

Research output: Research - peer-reviewArticle

Thoracic Aortic Aneurysm
Marfan Syndrome
Registries
Dissection
Connective Tissue Diseases
Self-Injurious Behavior
Research
Interaction
Developmental Disabilities
Pharmacology

Comparing behavioral treatment of feeding difficulties and tube dependence in children with cerebral palsy and autism spectrum disorder

Taylor, T., Kozlowski, A. M. & Girolami, P. A. 2017 In : NeuroRehabilitation. 41, 2, p. 395-402 8 p.

Research output: Research - peer-reviewArticle

Enteral Nutrition
Cerebral Palsy
Therapeutics
Autism Spectrum Disorder
Autistic Disorder

Comparing test-retest reliability of dynamic functional connectivity methods

Choe, A. S., Nebel, M. B., Barber, A. D., Cohen, J. R., Xu, Y., Pekar, J. J., Caffo, B. & Lindquist, M. A. Sep 1 2017 In : NeuroImage. 158, p. 155-175 21 p.

Research output: Research - peer-reviewArticle

Reproducibility of Results
Brain
Magnetic Resonance Imaging
Datasets
Connectome

Comparison of Autism Screening in Younger and Older Toddlers

Sturner, R., Howard, B., Bergmann, P., Stewart, L. & Afarian, T. E. Jul 21 2017 (Accepted/In press) In : Journal of Autism and Developmental Disorders. p. 1-9 9 p.

Research output: Research - peer-reviewArticle

Autistic Disorder
Primary Health Care
Research
Autism Spectrum Disorder

Conducting Preference Assessments for Youth With Disorders of Consciousness During Rehabilitation

Amari, A., Suskauer, S. J., Paasch, V., Grodin, L. K. & Slomine, B. S. Jun 8 2017 (Accepted/In press) In : Rehabilitation Psychology.

Research output: Research - peer-reviewArticle

Consciousness Disorders
Rehabilitation
Caregivers
Interviews
Population
Corpus Callosum
Brain Neoplasms
Names
Prospective Studies
Radiation

Deficiency of WARS2, encoding mitochondrial tryptophanyl tRNA synthetase, causes severe infantile onset leukoencephalopathy

Theisen, B. E., Rumyantseva, A., Cohen, J. S., Alcaraz, W. A., Shinde, D. N., Tang, S., Srivastava, S., Pevsner, J., Trifunovic, A. & Fatemi, A. 2017 (Accepted/In press) In : American Journal of Medical Genetics, Part A.

Research output: Research - peer-reviewArticle

Tryptophan-tRNA Ligase
Leukoencephalopathies
Amino Acyl-tRNA Synthetases
Intellectual Disability
Athetosis

Dendrimer-mediated delivery of N-acetyl cysteine to microglia in a mouse model of Rett syndrome

Nance, E., Kambhampati, S. P., Smith, E. S., Zhang, Z., Zhang, F., Singh, S., Johnston, M. V., Rangaramanujam, K., Blue, M. E. & Kannan, S. Dec 19 2017 In : Journal of Neuroinflammation. 14, 1, 252

Research output: Research - peer-reviewArticle

Rett Syndrome
Dendrimers
Microglia
Cysteine
Glutamic Acid

Description and Validation of a Computerized Behavioral Data Program: "bDataPro"

Bullock, C. E., Fisher, W. W. & Hagopian, L. P. Jun 1 2017 In : Behavior Analyst. 40, 1, p. 275-285 11 p.

Research output: Research - peer-reviewArticle

Detection and Quantification of Hydrogen Peroxide in Aqueous Solutions Using Chemical Exchange Saturation Transfer

Ryoo, D., Xu, X., Li, Y., Tang, J. A., Zhang, J., Van Zijl, P. C. M. & Liu, G. Jul 18 2017 In : Analytical Chemistry. 89, 14, p. 7758-7764 7 p.

Research output: Research - peer-reviewArticle

Saturation (materials composition)
Hydrogen Peroxide
Ion exchange
Nuclear magnetic resonance
Magnetic resonance

Detection of dynamic substrate binding using MRI

Yadav, N. N., Yang, X., Li, Y., Li, W., Liu, G. & Van Zijl, P. C. M. Dec 1 2017 In : Scientific Reports. 7, 1, 10138

Research output: Research - peer-reviewArticle

Protons
Magnetic Resonance Imaging
Water
Caffeine
Radio

Development of a radioligand for imaging V1a vasopressin receptors with PET

Naik, R., Valentine, H., Hall, A., Mathews, W. B., Harris, J. C., Carter, C. S., Dannals, R. F., Wong, D. F. & Horti, A. G. Oct 20 2017 In : European Journal of Medicinal Chemistry. 139, p. 644-656 13 p.

Research output: Research - peer-reviewArticle

Vasopressin Receptors
Positron emission tomography
Anesthetics
Brain
Imaging techniques

Development of attention to faces during the first 3 years: Influences of stimulus type

Libertus, K., Landa, R. J. & Haworth, J. L. Nov 17 2017 In : Frontiers in Psychology. 8, NOV, 1976

Research output: Research - peer-reviewArticle

Research

Do Parental Concerns Predict Developmental and Behavioral Diagnoses in a Developmental Clinic?

Yimgang, D. P., Albury, R. A. & Leppert, M. L. Mar 1 2017 In : Clinical Pediatrics. 56, 3, p. 263-267 5 p.

Research output: Research - peer-reviewArticle

Parents
Communication Disorders
Developmental Disabilities
Language Development
Autistic Disorder

Driving with the Rear View Mirror

Cataldo, M. F. Jun 1 2017 In : Behavior Analyst. 40, 1, p. 161-165 5 p.

Research output: Research - peer-reviewComment/debate

Ectopic calcification in pseudoxanthoma elasticum responds to inhibition of tissue-nonspecific alkaline phosphatase

Ziegler, S. G., Ferreira, C. R., Macfarlane, E. G., Riddle, R. C., Tomlinson, R. E., Chew, E. Y., Martin, L., Ma, C. T., Sergienko, E., Pinkerton, A. B., Millán, J. L., Gahl, W. A. & Dietz, H. C. Jun 7 2017 In : Science Translational Medicine. 9, 393, eaal1669

Research output: Research - peer-reviewArticle

Pseudoxanthoma Elasticum
Alkaline Phosphatase
Adenosine Triphosphate
Gene Targeting
Liver Failure

Epidemiology of estrogen and dementia in women with Down syndrome

Schupf, N., Lee, J. H., Pang, D., Zigman, W. B., Tycko, B., Krinsky-McHale, S. & Silverman, W. 2017 (Accepted/In press) In : Free Radical Biology and Medicine.

Research output: Research - peer-reviewArticle

Down Syndrome
Dementia
Estrogens
Epidemiology
Age of Onset
Sturge-Weber Syndrome
Neurocutaneous Syndromes
Tuberous Sclerosis
Neurofibromatosis 1
Epilepsy

Erratum to: An Assessment of the Necessary Strength of Behavioral Treatments for Severe Behavior Problems

Northup, J., Fisher, W., Kahng, S. W., Harrell, R. & Kurtz, P. Jul 26 2017 (Accepted/In press) In : Journal of Developmental and Physical Disabilities. p. 1 1 p.

Research output: Research - peer-reviewArticle

Names
Problem Behavior