Kennedy Krieger Institute

Research Output 1963 2018

2018

Accelerating locomotor savings in learning: Compressing four training days to one

Day, K. A., Leech, K. A., Roemmich, R. T. & Bastian, A. J. Jun 1 2018 In : Journal of neurophysiology. 119, 6, p. 2100-2113 14 p.

Research output: Contribution to journalArticle

Walking
Learning
Space Simulation
Aptitude
Nervous System

Altered task-related modulation of long-range connectivity in children with autism

Pillai, A. S., McAuliffe, D., Lakshmanan, B. M., Mostofsky, S. H., Crone, N. E. & Ewen, J. B. Feb 1 2018 In : Autism Research. 11, 2, p. 245-257 13 p.

Research output: Contribution to journalArticle

Autistic Disorder
Task Performance and Analysis
Electroencephalography
Autism Spectrum Disorder
Attention Deficit Disorder with Hyperactivity
Brain
Frontal Lobe
Temporal Lobe
Parietal Lobe

An update on pharmacotherapy of autism spectrum disorder in children and adolescents

Goel, R., Hong, J. S., Findling, R. L. & Ji, N. Y. Jan 2 2018 In : International Review of Psychiatry. 30, 1, p. 78-95 18 p.

Research output: Contribution to journalReview article

Complementary Therapies
Drug Therapy
Guanfacine
GABA Agents
Buspirone

Anxiety and mood disorder in children with autism spectrum disorder and ADHD

Gordon-Lipkin, E., Marvin, A. R., Law, J. K. & Lipkin, P. H. Apr 1 2018 In : Pediatrics. 141, 4, e20171377

Research output: Contribution to journalArticle

Attention Deficit Disorder with Hyperactivity
Anxiety Disorders
Mood Disorders
Autistic Disorder
Autism Spectrum Disorder

Are dopamine receptor and transporter changes in Rett syndrome reflected in Mecp2-deficient mice?

Wong, D. F., Blue, M. E., Brašić, J. R., Nandi, A., Valentine, H., Stansfield, K. H., Rousset, O., Bibat, G., Yablonski, M. E., Johnston, M. V., Gjedde, A. & Naidu, S. B. Sep 1 2018 In : Experimental Neurology. 307, p. 74-81 8 p.

Research output: Contribution to journalArticle

Rett Syndrome
Dopamine Plasma Membrane Transport Proteins
Dopamine Receptors
Positron-Emission Tomography
Autoradiography

Association of early postresuscitation hypotension with survival to discharge after targeted temperature management for pediatric out-of-hospital cardiac arrest secondary analysis of a randomized clinical trial

Topjian, A. A. , Moler, F. W. , Telford, R. , Holubkov, R. , Nadkarni, V. M. , Berg, R. A. , Dean, J. M. , Meert, K. L. , Hutchinson, J. S. , Newth, C. J. L. , Bennett, K. S. , Berger, J. T. , Pineda, J. A. , Koch, J. D. , Schleien, C. L. , Dalton, H. J. , Ofori-Amanfo, G. , Goodman, D. M. , Fink, E. L. , McQuillen, P. & 24 others Zimmerman, J. J., Thomas, N. J., Van Der Jagt, E. W., Porter, M. B., Meyer, M. T., Harrison, R., Pham, N., Schwarz, A. J., Nowak, J. E., Alten, J., Wheeler, D. S., Bhalala, U. S., Lidsky, K., Lloyd, E., Mathur, M., Shah, S., Wu, T., Theodorou, A. A., Sanders, R. C., Silverstein, F. S., Christensen, J. R., Slomine, B. S., Pemberton, V. L. & Browning, B. Feb 1 2018 In : JAMA Pediatrics. 172, 2, p. 143-153 11 p.

Research output: Contribution to journalArticle

Out-of-Hospital Cardiac Arrest
Pediatric Hospitals
Hypotension
Randomized Controlled Trials
Heart Arrest
Cranial Irradiation
Corpus Callosum
Anisotropy
Irradiation
Prospective Studies

ATAC-Seq analysis reveals a widespread decrease of chromatin accessibility in age-related macular degeneration

Wang, J., Zibetti, C., Shang, P., Sripathi, S. R., Zhang, P., Cano, M., Hoang, T., Xia, S., Ji, H., Merbs, S. L., Zack, D. J., Handa, J. T., Sinha, D., Blackshaw, S. & Qian, J. Dec 1 2018 In : Nature Communications. 9, 1, 1364

Research output: Contribution to journalArticle

accessibility
analysis
pathology
risk factor
footprint

Auditory brainstem pathology in autism spectrum disorder: A review

Pillion, J. P., Boatman-Reich, D. & Gordon, B. Jan 1 2018 In : Cognitive and Behavioral Neurology. 31, 2, p. 53-78 26 p.

Research output: Contribution to journalReview article

Brain Stem
Pathology
Sound Localization
Neural Pathways
Electrophysiology

Avoidant restrictive food intake disorder

González, M. L., Mulderink, T. D. & Girolami, P. A. Feb 13 2018 Principle-Based Stepped Care and Brief Psychotherapy for Integrated Care Settings. Springer International Publishing, p. 53-64 12 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Eating
food

Bioreducible Polymeric Nanoparticles Containing Multiplexed Cancer Stem Cell Regulating miRNAs Inhibit Glioblastoma Growth and Prolong Survival

Lopez-Bertoni, H., Kozielski, K. L., Rui, Y., Lal, B., Vaughan, H., Wilson, D. R., Mihelson, N., Eberhart, C. G., Laterra, J. & Green, J. J. Jul 11 2018 In : Nano Letters. 18, 7, p. 4086-4094 9 p.

Research output: Contribution to journalArticle

stem cells
Stem cells
Tumors
delivery
cancer

Brief Report: Self-Injurious Behaviors in Preschool Children with Autism Spectrum Disorder Compared to Other Developmental Delays and Disorders

Soke, G. N., Rosenberg, S. A., Rosenberg, C. R., Vasa, R. A., Lee, L. C. & DiGuiseppi, C. Feb 10 2018 (Accepted/In press) In : Journal of Autism and Developmental Disorders. p. 1-9 9 p.

Research output: Contribution to journalArticle

Self-Injurious Behavior
Developmental Disabilities
Preschool Children
Odds Ratio
Confidence Intervals

Burden of caregiving after a child's in-hospital cardiac arrest

Meert, K., Slomine, B. S., Christensen, J. R., Telford, R., Holubkov, R., Dean, J. M. & Moler, F. W. Jun 1 2018 In : Resuscitation. 127, p. 44-50 7 p.

Research output: Contribution to journalArticle

Heart Arrest
Caregivers
Pediatrics
Induced Hypothermia
Psychological Adaptation
Preschool Children
Caregivers
Post-Concussion Syndrome
Brain Concussion
Enuresis

CEST MRI of sepsis-induced acute kidney injury

Liu, J., Han, Z., Chen, G., Li, Y., Zhang, J., Xu, J., van Zijl, P. C. M., Zhang, S. & Liu, G. Aug 1 2018 In : NMR in biomedicine. 31, 8, e3942

Research output: Contribution to journalArticle

Acute Kidney Injury
Sepsis
Kidney
Lipopolysaccharides
Cerium

Chapter 3: Chemical Exchange Saturation Transfer (CEST) Contrast Agents

Ferrauto, G., Aime, S., McMahon, M. T., Morrow, J. R., Snyder, E. M., Li, A. & Bartha, R. Jan 1 2018 New Developments in NMR. 13 ed. Royal Society of Chemistry, Vol. 2018-January, p. 243-317 75 p. (New Developments in NMR; vol. 2018-January, no. 13)

Research output: Chapter in Book/Report/Conference proceedingChapter

Hole mobility
Contrast Media
Protons
Water
Micelles

Clinical Validity of Genes for Heritable Thoracic Aortic Aneurysm and Dissection

Renard, M. , Francis, C. , Ghosh, R. , Scott, A. F. , Witmer, P. D. , Adès, L. C. , Andelfinger, G. U. , Arnaud, P. , Boileau, C. , Callewaert, B. L. , Guo, D. , Hanna, N. , Lindsay, M. E. , Morisaki, H. , Morisaki, T. , Pachter, N. , Robert, L. , Van Laer, L. , Dietz, H. C. , Loeys, B. L. & 2 others Milewicz, D. M. & De Backer, J. Aug 7 2018 In : Journal of the American College of Cardiology. 72, 6, p. 605-615 11 p.

Research output: Contribution to journalArticle

Thoracic Aortic Aneurysm
Dissection
Genes
Aortic Diseases
Thoracic Diseases

Closing the loop: From motor neuroscience to neurorehabilitation

Roemmich, R. T. & Bastian, A. J. Jul 8 2018 In : Annual Review of Neuroscience. 41, p. 415-429 15 p.

Research output: Contribution to journalReview article

Neurosciences
Rehabilitation
Learning
Intuition
Theoretical Models

Cognitive Development One Year after Infantile Critical Pertussis∗

Johnston, M. V. Feb 1 2018 In : Pediatric Critical Care Medicine. 19, 2, p. 161-162 2 p.

Research output: Contribution to journalEditorial

Whooping Cough

Comparing proprioceptive acuity in the arm between joint space and task space

Sketch, S. M., Bastian, A. J. & Okamura, A. M. May 9 2018 IEEE Haptics Symposium, HAPTICS 2018 - Proceedings. IEEE Computer Society, Vol. 2018-March, p. 125-132 8 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Robotic arms
Kinematics

Co-occurring psychiatric conditions in autism spectrum disorder

Rosen, T. E., Mazefsky, C. A., Vasa, R. A. & Lerner, M. D. Jan 2 2018 In : International Review of Psychiatry. 30, 1, p. 40-61 22 p.

Research output: Contribution to journalReview article

Psychiatry
Wit and Humor
Individuality
Research
Anxiety Disorders

Correction to: Reduced Value-Driven Attentional Capture among Children with ADHD Compared to Typically Developing Control

Sali, A. W., Anderson, B. A., Yantis, S., Mostofsky, S. H. & Rosch, K. S. Apr 11 2018 (Accepted/In press) In : Journal of Abnormal Child Psychology. p. 1-2 2 p.

Research output: Contribution to journalArticle

Child Psychology

Correlating Oxygen Delivery During Cardiopulmonary Bypass With the Neurologic Injury Biomarker Ubiquitin C-Terminal Hydrolase L1 (UCH-L1)

Magruder, J. T., Fraser, C. D., Grimm, J. C., Crawford, T. C., Beaty, C. A., Suarez-Pierre, A., Hayes, R. L., Johnston, M. V. & Baumgartner, W. A. Jan 1 2018 (Accepted/In press) In : Journal of Cardiothoracic and Vascular Anesthesia.

Research output: Contribution to journalArticle

Ubiquitin Thiolesterase
Nervous System Trauma
Cardiopulmonary Bypass
Biomarkers
Oxygen

Creating flexible motor memories in human walking

Leech, K. A., Roemmich, R. T. & Bastian, A. J. Dec 1 2018 In : Scientific Reports. 8, 1, 94

Research output: Contribution to journalArticle

Walking
Learning
Aptitude
Gait
Nervous System

Crizotinib and erlotinib inhibits growth of c-Met+/EGFRvIII+ primary human glioblastoma xenografts

Goodwin, C. R., Rath, P., Oyinlade, O., Lopez, H., Mughal, S., Xia, S., Li, Y., Kaur, H., Zhou, X., Ahmed, A. K., Ho, S., Olivi, A. & Lal, B. Aug 1 2018 In : Clinical Neurology and Neurosurgery. 171, p. 26-33 8 p.

Research output: Contribution to journalArticle

Glioblastoma
Heterografts
Growth
Epidermal Growth Factor Receptor
Neoplasms
Developmental Disabilities
Intellectual Disability
Epilepsy
Mutation

Detection and differentiation of Cys, Hcy and GSH mixtures by 19F NMR probe

Yang, S., Zeng, Q., Guo, Q., Chen, S., Liu, H., Liu, M., McMahon, M. T. & Zhou, X. Jul 1 2018 In : Talanta. 184, p. 513-519 7 p.

Research output: Contribution to journalArticle

Urea fertilizers
Nuclear magnetic resonance
Negative impedance converters
Addition reactions
Cyclization

Developmental Trajectory of Motor Deficits in Preschool Children with ADHD

Sweeney, K. L., Ryan, M., Schneider, H., Ferenc, L., Denckla, M. B. & Mark Mahone, E. May 13 2018 (Accepted/In press) In : Developmental Neuropsychology. p. 1-11 11 p.

Research output: Contribution to journalArticle

Preschool Children
Fingers
Neurologic Examination
Physical Examination
Longitudinal Studies

Diagnosis and management of Duchenne muscular dystrophy, part 1: diagnosis, and neuromuscular, rehabilitation, endocrine, and gastrointestinal and nutritional management

DMD Care Considerations Working Group Mar 1 2018 In : The Lancet Neurology. 17, 3, p. 211-212 2 p.

Research output: Contribution to journalReview article

Duchenne Muscular Dystrophy
Rehabilitation
Patient Transfer
Adrenal Insufficiency
Neuromuscular Diseases

Dose–volume metrics and their relation to memory performance in pediatric brain tumor patients: A preliminary study

Raghubar, K. P., Lamba, M., Cecil, K. M., Yeates, K. O., Mahone, E. M., Limke, C., Grosshans, D., Beckwith, T. J. & Ris, M. D. Sep 1 2018 In : Pediatric Blood and Cancer. 65, 9, e27245

Research output: Contribution to journalArticle

Brain Neoplasms
Radiation
Pediatrics
Brain
Learning

Early detection of hypothermic neuroprotection using T2-weighted magnetic resonance imaging in a mouse model of hypoxic ischemic encephalopathy

Doman, S. E., Girish, A., Nemeth, C. L., Drummond, G. T., Carr, P., Garcia, M. S., Johnston, M. V., Kannan, S., Fatemi, A., Zhang, J. & Wilson, M. A. May 8 2018 In : Frontiers in Neurology. 9, MAY, 304

Research output: Contribution to journalArticle

Brain Hypoxia-Ischemia
Ischemia
Magnetic Resonance Imaging
Hypothermia
Wounds and Injuries

ECT for Self-Injurious Behavior in Autism: A New Indication

Wachtel, L. E., Kellner, C. H. & Fink, M. Feb 1 2018 In : Psychiatric Times. 35, 2, p. 6-9 4 p.

Research output: Contribution to journalArticle

Self-Injurious Behavior
Autistic Disorder

Editorial

Vasa, R. A. Jan 2 2018 In : International Review of Psychiatry. 30, 1, p. 1-2 2 p.

Research output: Contribution to journalEditorial

Aptitude
Psychiatry
Parents
Autism Spectrum Disorder
Mentoring

Electroconvulsive therapy for self-injurious behaviour in autism spectrum disorders: Recognizing catatonia is key

Wachtel, L. E., Shorter, E. & Fink, M. Mar 1 2018 In : Current Opinion in Psychiatry. 31, 2, p. 116-122 7 p.

Research output: Contribution to journalReview article

Catatonia
Self-Injurious Behavior
Electroconvulsive Therapy
Wounds and Injuries
Autism Spectrum Disorder

Elevated creatinine in a patient on IVIG-therapy

Knezevic, C. E., Ness, M. A., Kratz, L. E. & Marzinke, M. A. Nov 1 2018 In : Clinica Chimica Acta. 486, p. 94-97 4 p.

Research output: Contribution to journalArticle

Passive Immunization
Intravenous Immunoglobulins
Proline
Creatinine
Sarcosine Oxidase

Engineering functional and histological regeneration of vascularized skeletal muscle

Gilbert-Honick, J., Iyer, S. R., Somers, S. M., Lovering, R. M., Wagner, K., Mao, H. Q. & Grayson, W. L. May 1 2018 In : Biomaterials. 164, p. 70-79 10 p.

Research output: Contribution to journalArticle

Muscle
Regeneration
Skeletal Muscle
Scaffolds
Muscles

Exploring Relationships Between Negative Cognitions and Anxiety Symptoms in Youth With Autism Spectrum Disorder

Keefer, A., Kreiser, N. L., Singh, V., Blakeley-Smith, A., Reaven, J. & Vasa, R. A. Jan 1 2018 (Accepted/In press) In : Behavior Therapy.

Research output: Contribution to journalArticle

Cognition
Anxiety
Autism Spectrum Disorder
Uncertainty
Depression
Tourette Syndrome
gamma-Aminobutyric Acid
Glutamic Acid
Magnetic Resonance Spectroscopy
Motor Cortex

Global identification of Small Ubiquitin-related Modifier (SUMO) substrates reveals crosstalk between SUMOylation and phosphorylation promotes cell migration

Uzoma, I., Hu, J., Cox, E., Xia, S., Zhou, J., Rho, H. S., Guzzo, C., Paul, C., Ajala, O., Goodwin, C. R., Jeong, J., Moore, C., Zhang, H., Meluh, P., Blackshaw, S., Matunis, M., Qian, J. & Zhu, H. May 1 2018 In : Molecular and Cellular Proteomics. 17, 5, p. 871-888 18 p.

Research output: Contribution to journalArticle

Sumoylation
Ubiquitin
Cell Movement
Phosphorylation
Rotary engines

Heterozygous IDH1R132H/WT created by “single base editing” inhibits human astroglial cell growth by downregulating YAP

Wei, S., Wang, J., Oyinlade, O., Ma, D., Wang, S., Kratz, L., Lal, B., Xu, Q., Liu, S., Shah, S. R., Zhang, H., Li, Y., Quiñones-Hinojosa, A., Zhu, H., Huang, Z. Y., Cheng, L., Qian, J. & Xia, S. May 30 2018 (Accepted/In press) In : Oncogene. p. 1-15 15 p.

Research output: Contribution to journalArticle

Isocitrate Dehydrogenase
Down-Regulation
Growth
Proteins
Mutation

Home-Based, Therapist-Assisted, Therapy for Young Children With Primary Complex Motor Stereotypies

Singer, H. S., Rajendran, S., Waranch, H. R. & Mahone, E. M. Jan 1 2018 (Accepted/In press) In : Pediatric Neurology.

Research output: Contribution to journalArticle

Telephone
Lost to Follow-Up
Therapeutics
Attention Deficit Disorder with Hyperactivity
Parents
Self-Injurious Behavior
behavior analysis
Biomarkers
Therapeutics
physician's care

Improved estimation of subject-level functional connectivity using full and partial correlation with empirical Bayes shrinkage

Mejia, A. F., Nebel, M. B., Barber, A. D., Choe, A. S., Pekar, J. J., Caffo, B. S. & Lindquist, M. A. May 15 2018 In : NeuroImage. 172, p. 478-491 14 p.

Research output: Contribution to journalArticle

Bayes Theorem
Connectome
Research Design
Magnetic Resonance Imaging

Krüppel-like factor 4 (KLF4) induces mitochondrial fusion and increases spare respiratory capacity of human glioblastoma cells

Wang, S., Shi, X., Wei, S., Ma, D., Oyinlade, O., Lv, S. Q., Ying, M., Zhang, Y. A., Claypool, S. M., Watkins, P. & Xia, S. Jan 1 2018 In : Journal of Biological Chemistry. 293, 17, p. 6544-6555 12 p.

Research output: Contribution to journalArticle

Mitochondrial Dynamics
Glioblastoma
Metabolism
Fusion reactions
Cells

Leo Kanner and autism. 75-year perspective

Harris, J. Jan 2 2018 In : International Review of Psychiatry. 30, 1, p. 3-17 15 p.

Research output: Contribution to journalReview article

Autistic Disorder
Neuroimaging
Diagnostic and Statistical Manual of Mental Disorders
Primates
Transgenic Mice

Lesch-Nyhan syndrome and its variants: Examining the behavioral and neurocognitive phenotype

Harris, J. C. Mar 1 2018 In : Current Opinion in Psychiatry. 31, 2, p. 96-102 7 p.

Research output: Contribution to journalReview article

Lesch-Nyhan Syndrome
Psychiatry
Phenotype
Wounds and Injuries
Dental Equipment
Postnatal Care
Health Behavior
Postpartum Period
Mothers
Dental Care