Kennedy Krieger Institute

Research Output 1963 2018

2018

Accelerating locomotor savings in learning: Compressing four training days to one

Day, K. A., Leech, K. A., Roemmich, R. T. & Bastian, A. J., Jun 1 2018, In : Journal of Neurophysiology. 119, 6, p. 2100-2113 14 p.

Research output: Contribution to journalArticle

Walking
Learning
Space Simulation
Aptitude
Nervous System

Acute kidney injury after out of hospital pediatric cardiac arrest

Cornell, T. T., Selewski, D. T., Alten, J. A., Askenazi, D., Fitzgerald, J. C., Topjian, A., Holubkov, R., Page, K., Slomine, B. S., Christensen, J. R., Dean, J. M. & Moler, F. W., Oct 1 2018, In : Resuscitation. 131, p. 63-68 6 p.

Research output: Contribution to journalArticle

Out-of-Hospital Cardiac Arrest
Acute Kidney Injury
Induced Hypothermia
Heart Arrest
Lactates
Dronabinol
Cyclooxygenase 2
Astrocytes
Cannabis
Schizophrenia

A Dual-Learning Paradigm Simultaneously Improves Multiple Features of Gait Post-Stroke

Cherry-Allen, K. M., Statton, M. A., Celnik, P. A. & Bastian, A. J., Jan 1 2018, (Accepted/In press) In : Neurorehabilitation and neural repair.

Research output: Contribution to journalArticle

Gait
Stroke
Learning
Walking
Knee

A generative-discriminative basis learning framework to predict clinical severity from resting state functional MRI data

D’Souza, N. S., Nebel, M. B., Wymbs, N., Mostofsky, S. & Venkataraman, A., Jan 1 2018, Medical Image Computing and Computer Assisted Intervention – MICCAI 2018 - 21st International Conference, 2018, Proceedings. Frangi, A. F., Davatzikos, C., Fichtinger, G., Alberola-López, C. & Schnabel, J. A. (eds.). Springer Verlag, p. 163-171 9 p. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); vol. 11072 LNCS).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Functional Magnetic Resonance Imaging
Correlation Matrix
Predict
Matrix Factorization
Nonlinear Regression

Altered task-related modulation of long-range connectivity in children with autism

Pillai, A. S., McAuliffe, D., Lakshmanan, B. M., Mostofsky, S. H., Crone, N. E. & Ewen, J. B., Feb 1 2018, In : Autism Research. 11, 2, p. 245-257 13 p.

Research output: Contribution to journalArticle

Autistic Disorder
Task Performance and Analysis
Electroencephalography
Autism Spectrum Disorder

Anaesthesia recommendations for patients suffering From: Sturge-Weber syndrome

McCaul, C., Comi, A. M. S. & Juhasz, C., Oct 1 2018, In : Anasthesiologie und Intensivmedizin. 59, 10, p. S596-S604

Research output: Contribution to journalReview article

Sturge-Weber Syndrome
Hemangioma
Anesthesia
Seizures
Nevus

Analysis of KLF4 regulated genes in cancer cells reveals a role of DNA methylation in promoter- enhancer interactions

Oyinlade, O., Wei, S., Kammers, K., Liu, S., Wang, S., Ma, D., Huang, Z. Y., Qian, J., Zhu, H., Wan, J. & Xia, S., Jan 1 2018, (Accepted/In press) In : Epigenetics.

Research output: Contribution to journalArticle

Neoplasm Genes
DNA Methylation
Glioblastoma
Gene Expression
Genetic Promoter Regions

Anesthesia and the developing brain: A way forward for laboratory and clinical research

Disma, N., O'Leary, J. D., Loepke, A. W., Brambrink, A. M., Becke, K., Clausen, N. G., De Graaff, J. C., Liu, F., Hansen, T. G., McCann, M. E., Salorio, C. F., Soriano, S., Sun, L. S., Szmuk, P., Warner, D. O., Vutskits, L. & Davidson, A. J., Sep 1 2018, In : Paediatric anaesthesia. 28, 9, p. 758-763 6 p.

Research output: Contribution to journalArticle

Anesthesia
Brain
Research
Anesthetics
Medical Laboratory Science
Attention Deficit Disorder with Hyperactivity
Brain
Frontal Lobe
Temporal Lobe
Parietal Lobe

An update on pharmacotherapy of autism spectrum disorder in children and adolescents

Goel, R., Hong, J. S., Findling, R. L. & Ji, N. Y., Jan 2 2018, In : International Review of Psychiatry. 30, 1, p. 78-95 18 p.

Research output: Contribution to journalReview article

Complementary Therapies
Drug Therapy
Guanfacine
GABA Agents
Buspirone

Anxiety and mood disorder in children with autism spectrum disorder and ADHD

Gordon-Lipkin, E., Marvin, A. R., Law, J. K. & Lipkin, P. H., Apr 1 2018, In : Pediatrics. 141, 4, e20171377.

Research output: Contribution to journalArticle

Attention Deficit Disorder with Hyperactivity
Anxiety Disorders
Mood Disorders
Autistic Disorder
Autism Spectrum Disorder

Are dopamine receptor and transporter changes in Rett syndrome reflected in Mecp2-deficient mice?

Wong, D. F., Blue, M. E., Brašić, J. R., Nandi, A., Valentine, H., Stansfield, K. H., Rousset, O., Bibat, G., Yablonski, M. E., Johnston, M. V., Gjedde, A. & Naidu, S. B., Sep 1 2018, In : Experimental Neurology. 307, p. 74-81 8 p.

Research output: Contribution to journalArticle

Rett Syndrome
Dopamine Plasma Membrane Transport Proteins
Dopamine Receptors
Positron-Emission Tomography
Autoradiography

A Role for βA3/A1-Crystallin in Type 2 EMT of RPE Cells Occurring in Dry Age-Related Macular Degeneration

Ghosh, S., Shang, P., Terasaki, H., Stepicheva, N., Hose, S., Yazdankhah, M., Weiss, J., Sakamoto, T., Bhutto, I. A., Xia, S., Zigler, J. S., Kannan, R., Qian, J., Handa, J. & Sinha, D., Mar 20 2018, In : Investigative ophthalmology & visual science. 59, 4, p. AMD104-AMD113

Research output: Contribution to journalArticle

Crystallins
Epithelial-Mesenchymal Transition
Macular Degeneration
Vimentin
Cadherins

Association of early postresuscitation hypotension with survival to discharge after targeted temperature management for pediatric out-of-hospital cardiac arrest secondary analysis of a randomized clinical trial

Topjian, A. A., Moler, F. W., Telford, R., Holubkov, R., Nadkarni, V. M., Berg, R. A., Dean, J. M., Meert, K. L., Hutchinson, J. S., Newth, C. J. L., Bennett, K. S., Berger, J. T., Pineda, J. A., Koch, J. D., Schleien, C. L., Dalton, H. J., Ofori-Amanfo, G., Goodman, D. M., Fink, E. L., McQuillen, P. & 24 othersZimmerman, J. J., Thomas, N. J., Van Der Jagt, E. W., Porter, M. B., Meyer, M. T., Harrison, R., Pham, N., Schwarz, A. J., Nowak, J. E., Alten, J., Wheeler, D. S., Bhalala, U. S., Lidsky, K., Lloyd, E., Mathur, M., Shah, S., Wu, T., Theodorou, A. A., Sanders, R. C., Silverstein, F. S., Christensen, J. R., Slomine, B. S., Pemberton, V. L. & Browning, B., Feb 1 2018, In : JAMA Pediatrics. 172, 2, p. 143-153 11 p.

Research output: Contribution to journalArticle

Out-of-Hospital Cardiac Arrest
Pediatric Hospitals
Hypotension
Randomized Controlled Trials
Heart Arrest
Cranial Irradiation
Corpus Callosum
Anisotropy
Irradiation
Prospective Studies

ASTN2 modultes synaptic strength by trafficking and degradation of surface proteins

Behesti, H., Fore, T. R., Wu, P., Horn, Z., Leppert, M. L., Hull, C. & Hattena, M. E., Oct 9 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 41, p. E9717-E9726

Research output: Contribution to journalArticle

Purkinje Cells
Membrane Proteins
Transport Vesicles
Dendritic Spines
Gene Dosage

ATAC-Seq analysis reveals a widespread decrease of chromatin accessibility in age-related macular degeneration

Wang, J., Zibetti, C., Shang, P., Sripathi, S. R., Zhang, P., Cano, M., Hoang, T., Xia, S., Ji, H., Merbs, S. L., Zack, D. J., Handa, J. T., Sinha, D., Blackshaw, S. & Qian, J., Dec 1 2018, In : Nature Communications. 9, 1, 1364.

Research output: Contribution to journalArticle

chromatin
degeneration
Macular Degeneration
Chromatin
epithelium

Auditory brainstem pathology in autism spectrum disorder: A review

Pillion, J. P., Boatman-Reich, D. & Gordon, B., Jan 1 2018, In : Cognitive and Behavioral Neurology. 31, 2, p. 53-78 26 p.

Research output: Contribution to journalReview article

Brain Stem
Pathology
Sound Localization
Neural Pathways
Electrophysiology

Avoidant restrictive food intake disorder

González, M. L., Mulderink, T. D. & Girolami, P. A., Feb 13 2018, Principle-Based Stepped Care and Brief Psychotherapy for Integrated Care Settings. Springer International Publishing, p. 53-64 12 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Eating
food

Biological scaffold-mediated delivery of myostatin inhibitor promotes a regenerative immune response in an animal model of Duchenne muscular dystrophy

Estrellas, K. M., Chung, L., Cheu, L. A., Sadtler, K., Majumdar, S., Mula, J., Wolf, M. T., Elisseeff, J. H. & Wagner, K. R., Jan 1 2018, In : Journal of Biological Chemistry. 293, 40, p. 15594-15605 12 p.

Research output: Contribution to journalArticle

Myostatin
Duchenne Muscular Dystrophy
Hydrogel
Scaffolds
Muscle

Bioreducible Polymeric Nanoparticles Containing Multiplexed Cancer Stem Cell Regulating miRNAs Inhibit Glioblastoma Growth and Prolong Survival

Lopez-Bertoni, H., Kozielski, K. L., Rui, Y., Lal, B., Vaughan, H., Wilson, D. R., Mihelson, N., Eberhart, C. G., Laterra, J. J. & Green, J., Jul 11 2018, In : Nano Letters. 18, 7, p. 4086-4094 9 p.

Research output: Contribution to journalArticle

stem cells
Stem cells
Tumors
delivery
cancer

Brief Report: Self-Injurious Behaviors in Preschool Children with Autism Spectrum Disorder Compared to Other Developmental Delays and Disorders

Soke, G. N., Rosenberg, S. A., Rosenberg, C. R., Vasa, R. A., Lee, L. C. & DiGuiseppi, C., Feb 10 2018, (Accepted/In press) In : Journal of Autism and Developmental Disorders. p. 1-9 9 p.

Research output: Contribution to journalArticle

Self-Injurious Behavior
Developmental Disabilities
Preschool Children
Odds Ratio
Confidence Intervals

Burden of caregiving after a child's in-hospital cardiac arrest

Meert, K., Slomine, B. S., Christensen, J. R., Telford, R., Holubkov, R., Dean, J. M. & Moler, F. W., Jun 1 2018, In : Resuscitation. 127, p. 44-50 7 p.

Research output: Contribution to journalArticle

Heart Arrest
Caregivers
Pediatrics
Induced Hypothermia
Psychological Adaptation
Preschool Children
Caregivers
Post-Concussion Syndrome
Brain Concussion
Enuresis
Loeys-Dietz Syndrome
Carotid Arteries
Kaplan-Meier Estimate
Proportional Hazards Models
Angiography

CEST MRI of 3-O-methyl-D-glucose uptake and accumulation in brain tumors

Sehgal, A. A., Li, Y., Lal, B., Yadav, N. N., Xu, X., Xu, J., Laterra, J. & van Zijl, P. C. M., Jan 1 2018, (Accepted/In press) In : Magnetic resonance in medicine.

Research output: Contribution to journalArticle

3-O-Methylglucose
Brain Neoplasms
Contrast Media
Glucose
Neoplasms

CEST MRI of sepsis-induced acute kidney injury

Liu, J., Han, Z., Chen, G., Li, Y., Zhang, J., Xu, J., van Zijl, P. C. M., Zhang, S. & Liu, G., Aug 1 2018, In : NMR in Biomedicine. 31, 8, e3942.

Research output: Contribution to journalArticle

Magnetic resonance imaging
Magnetization
Molecular imaging
Histology
Biomarkers

Chapter 3: Chemical Exchange Saturation Transfer (CEST) Contrast Agents

Ferrauto, G., Aime, S., McMahon, M. T., Morrow, J. R., Snyder, E. M., Li, A. & Bartha, R., Jan 1 2018, New Developments in NMR. 13 ed. Royal Society of Chemistry, Vol. 2018-January. p. 243-317 75 p. (New Developments in NMR; vol. 2018-January, no. 13).

Research output: Chapter in Book/Report/Conference proceedingChapter

Contrast Media
Protons
Water
Micelles
Liposomes

Children's brains are different

Bastian, A., Apr 24 2018, Think Tank: Forty Neuroscientists Explore the Biological Roots of Human Experience. Yale University Press, p. 40-44 5 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Brain

Clinical and functional characterization of the recurrent TUBA1A p.(ARG2HIS) mutation

Gardner, J. F., Cushion, T. D., Niotakis, G., Olson, H. E., Grant, P. E., Scott, R. H., Stoodley, N., Cohen, J. S., Naidu, S., Attie-Bitach, T., Bonnières, M., Boutaud, L., Encha-Razavi, F., Palmer-Smith, S. M., Mugalaasi, H., Mullins, J. G. L., Pilz, D. T. & Fry, A. E., Aug 7 2018, In : Brain Sciences. 8, 8, 145.

Research output: Contribution to journalArticle

Tubulin
Mutation
Microtubules
Brain
Microcephaly

Clinical Validity of Genes for Heritable Thoracic Aortic Aneurysm and Dissection

Renard, M., Francis, C., Ghosh, R., Scott, A. F., Witmer, P. D., Adès, L. C., Andelfinger, G. U., Arnaud, P., Boileau, C., Callewaert, B. L., Guo, D., Hanna, N., Lindsay, M. E., Morisaki, H., Morisaki, T., Pachter, N., Robert, L., Van Laer, L., Dietz, H. C., Loeys, B. L. & 2 othersMilewicz, D. M. & De Backer, J., Aug 7 2018, In : Journal of the American College of Cardiology. 72, 6, p. 605-615 11 p.

Research output: Contribution to journalArticle

Thoracic Aortic Aneurysm
Dissection
Genes
Aortic Diseases
Thoracic Diseases

Closing the loop: From motor neuroscience to neurorehabilitation

Roemmich, R. T. & Bastian, A. J., Jul 8 2018, In : Annual Review of Neuroscience. 41, p. 415-429 15 p.

Research output: Contribution to journalReview article

Neurosciences
Rehabilitation
Learning
Intuition
Theoretical Models

Cognitive Development One Year after Infantile Critical Pertussis∗

Johnston, M. V., Feb 1 2018, In : Pediatric Critical Care Medicine. 19, 2, p. 161-162 2 p.

Research output: Contribution to journalEditorial

Whooping Cough

Comparing fully automated state-of-the-art cerebellum parcellation from magnetic resonance images

Carass, A., Cuzzocreo, J. L., Han, S., Hernandez-Castillo, C. R., Rasser, P. E., Ganz, M., Beliveau, V., Dolz, J., Ben Ayed, I., Desrosiers, C., Thyreau, B., Romero, J. E., Coupé, P., Manjón, J. V., Fonov, V. S., Collins, D. L., Ying, S. H., Onyike, C. U., Crocetti, D., Landman, B. A. & 3 othersMostofsky, S. H., Thompson, P. M. & Prince, J. L., Dec 1 2018, In : NeuroImage. 183, p. 150-172 23 p.

Research output: Contribution to journalArticle

Cerebellum
Magnetic Resonance Spectroscopy
Pathology
Cerebellar Ataxia
Autistic Disorder

Comparing proprioceptive acuity in the arm between joint space and task space

Sketch, S. M., Bastian, A. J. & Okamura, A. M., May 9 2018, IEEE Haptics Symposium, HAPTICS 2018 - Proceedings. IEEE Computer Society, Vol. 2018-March. p. 125-132 8 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Robotic arms
Kinematics

Co-occurring psychiatric conditions in autism spectrum disorder

Rosen, T. E., Mazefsky, C. A., Vasa, R. A. & Lerner, M. D., Jan 2 2018, In : International Review of Psychiatry. 30, 1, p. 40-61 22 p.

Research output: Contribution to journalReview article

Psychiatry
Wit and Humor
Individuality
Research
Anxiety Disorders

Correction to: Reduced Value-Driven Attentional Capture among Children with ADHD Compared to Typically Developing Control

Sali, A. W., Anderson, B. A., Yantis, S., Mostofsky, S. H. & Rosch, K. S., Apr 11 2018, (Accepted/In press) In : Journal of Abnormal Child Psychology. p. 1-2 2 p.

Research output: Contribution to journalArticle

Child Psychology

Correlating Oxygen Delivery During Cardiopulmonary Bypass With the Neurologic Injury Biomarker Ubiquitin C-Terminal Hydrolase L1 (UCH-L1)

Magruder, J. T., Fraser, C. D., Grimm, J. C., Crawford, T. C., Beaty, C. A., Suarez-Pierre, A., Hayes, R. L., Johnston, M. V. & Baumgartner, W. A., Jan 1 2018, (Accepted/In press) In : Journal of Cardiothoracic and Vascular Anesthesia.

Research output: Contribution to journalArticle

Ubiquitin Thiolesterase
Nervous System Trauma
Cardiopulmonary Bypass
Biomarkers
Oxygen

Creating flexible motor memories in human walking

Leech, K. A., Roemmich, R. T. & Bastian, A. J., Dec 1 2018, In : Scientific Reports. 8, 1, 94.

Research output: Contribution to journalArticle

Walking
Learning
Aptitude
Gait
Nervous System

Crizotinib and erlotinib inhibits growth of c-Met+/EGFRvIII+ primary human glioblastoma xenografts

Goodwin, C. R., Rath, P., Oyinlade, O., Lopez, H., Mughal, S., Xia, S., Li, Y., Kaur, H., Zhou, X., Ahmed, A. K., Ho, S., Olivi, A. & Lal, B., Aug 1 2018, In : Clinical Neurology and Neurosurgery. 171, p. 26-33 8 p.

Research output: Contribution to journalArticle

Glioblastoma
Heterografts
Growth
Epidermal Growth Factor Receptor
Neoplasms

Dendrimer–N-acetyl-L-cysteine modulates monophagocytic response in adrenoleukodystrophy

Turk, B. R., Nemeth, C. L., Marx, J. S., Tiffany, C. W., Jones, R. O., Theisen, B., Kambhampati, S., Ramireddy, R., Singh, S., Rosen, M., Kaufman, M. L., Murray, C. F., Watkins, P. A., Kannan, S., Rangaramanujam, K. & Fatemi, A., Sep 1 2018, In : Annals of neurology. 84, 3, p. 452-462 11 p.

Research output: Contribution to journalArticle

Adrenoleukodystrophy
Dendrimers
Acetylcysteine
Cysteine
Glutamic Acid
Developmental Disabilities
Intellectual Disability
Epilepsy
Mutation

Detection and differentiation of Cys, Hcy and GSH mixtures by 19F NMR probe

Yang, S., Zeng, Q., Guo, Q., Chen, S., Liu, H., Liu, M., Mcmahon, M. T. & Zhou, X., Jul 1 2018, In : Talanta. 184, p. 513-519 7 p.

Research output: Contribution to journalArticle

Homocysteine
Cysteine
Magnetic Resonance Spectroscopy
Nuclear magnetic resonance
Addition reactions

Developmental Trajectory of Motor Deficits in Preschool Children with ADHD

Sweeney, K. L., Ryan, M., Schneider, H., Ferenc, L., Denckla, M. B. & Mark Mahone, E., May 13 2018, (Accepted/In press) In : Developmental Neuropsychology. p. 1-11 11 p.

Research output: Contribution to journalArticle

Preschool Children
Fingers
Neurologic Examination
Physical Examination
Longitudinal Studies

Diagnosis and management of Duchenne muscular dystrophy, part 1: diagnosis, and neuromuscular, rehabilitation, endocrine, and gastrointestinal and nutritional management

DMD Care Considerations Working Group, Mar 1 2018, In : The Lancet Neurology. 17, 3, p. 211-212 2 p.

Research output: Contribution to journalReview article

Duchenne Muscular Dystrophy
Rehabilitation
Patient Transfer
Adrenal Insufficiency
Neuromuscular Diseases

Dose–volume metrics and their relation to memory performance in pediatric brain tumor patients: A preliminary study

Raghubar, K. P., Lamba, M., Cecil, K. M., Yeates, K. O., Mahone, E. M., Limke, C., Grosshans, D., Beckwith, T. J. & Ris, M. D., Sep 1 2018, In : Pediatric Blood and Cancer. 65, 9, e27245.

Research output: Contribution to journalArticle

Brain Neoplasms
Radiation
Pediatrics
Brain
Learning

Early childhood undernutrition increases risk of hearing loss in young adulthood in rural Nepal

Emmett, S. D., Schmitz, J., Karna, S. L., Khatry, S. K., Wu, L., LeClerq, S. C., Pillion, J. & West, K. P., Feb 1 2018, In : American Journal of Clinical Nutrition. 107, 2, p. 268-277 10 p.

Research output: Contribution to journalArticle

Nepal
Hearing Loss
Malnutrition
Thinness
Growth Disorders

Early detection of hypothermic neuroprotection using T2-weighted magnetic resonance imaging in a mouse model of hypoxic ischemic encephalopathy

Doman, S. E., Girish, A., Nemeth, C. L., Drummond, G. T., Carr, P., Garcia, M. S., Johnston, M. V., Kannan, S., Fatemi, A., Zhang, J. & Wilson, M. A., May 8 2018, In : Frontiers in Neurology. 9, MAY, 304.

Research output: Contribution to journalArticle

Brain Hypoxia-Ischemia
Ischemia
Magnetic Resonance Imaging
Hypothermia
Wounds and Injuries