Johns Hopkins University

Research Output 1914 2019

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2019

Acute myeloid leukemia stem cell heterogeneity and its clinical relevance

Karantanos, T. & Jones, R. J., Jan 1 2019, Advances in Experimental Medicine and Biology. Springer New York LLC, p. 153-169 17 p. (Advances in Experimental Medicine and Biology; vol. 1139).

Research output: Chapter in Book/Report/Conference proceedingChapter

Myeloid Progenitor Cells
Stem cells
Acute Myeloid Leukemia
Myeloid Cells
Leukemia

An overview of DNA analytical methods

Arboleda, V. A. & Xian, R., Jan 1 2019, Methods in Molecular Biology. Humana Press Inc., p. 385-402 18 p. (Methods in Molecular Biology; vol. 1897).

Research output: Chapter in Book/Report/Conference proceedingChapter

Precision Medicine
Technology
DNA
Medicine
Epigenomics

Apparent acetaminophen toxicity in a patient with transaldolase deficiency

Lee-Barber, J., English, T. E., Britton, J. F., Sobreira, N., Goldstein, J., Valle, D. & Bjornsson, H. T., Jan 1 2019, JIMD Reports. Springer, p. 9-15 7 p. (JIMD Reports; vol. 44).

Research output: Chapter in Book/Report/Conference proceedingChapter

Transaldolase
Acetaminophen
Toxicity
Liver
Liver Failure

A pyrophosphatase-coupled assay to monitor the NTase activity of cGAS

Hooy, R. M. & Sohn, J., Jan 1 2019, Methods in Enzymology. Academic Press Inc., (Methods in Enzymology).

Research output: Chapter in Book/Report/Conference proceedingChapter

Pyrophosphatases
Transferases
Assays
GMP synthase (glutamine-hydrolyzing)
Throughput

Assessment of inflammasome and type I IFN responses to DNA viruses and DNA PAMPS

Massaccesi, G. & Chattergoon, M. A., Jan 1 2019, Methods in Enzymology. Academic Press Inc., (Methods in Enzymology).

Research output: Chapter in Book/Report/Conference proceedingChapter

Inflammasomes
DNA Viruses
Viruses
DNA
Interferons

A tale of the good and bad: Cell senescence in bone homeostasis and disease

Liu, X. & Wan, M., Jan 1 2019, International Review of Cell and Molecular Biology. Elsevier Inc., (International Review of Cell and Molecular Biology).

Research output: Chapter in Book/Report/Conference proceedingChapter

Cell Aging
Bone Diseases
Bone
Homeostasis
Bone Development

Biochemical analysis of naturally processed antigenic peptides presented by MHC class I molecules

Kanaseki, T. & Shastri, N., Jan 1 2019, Methods in Molecular Biology. Humana Press Inc., p. 101-108 8 p. (Methods in Molecular Biology; vol. 1988).

Research output: Chapter in Book/Report/Conference proceedingChapter

Peptides
T-Lymphocytes
Antigen Receptors
Hybridomas
Reverse-Phase Chromatography

Bittersweet tumor development and progression: Emerging roles of epithelial plasticity glycosylations

Phillips, R. M., Lam, C., Wang, H. & Tran, P. T., Jan 1 2019, Advances in Cancer Research. Academic Press Inc., (Advances in Cancer Research).

Research output: Chapter in Book/Report/Conference proceedingChapter

Glycosylation
Epithelial-Mesenchymal Transition
Hexosamines
Biosynthetic Pathways
Neoplasms

Brain death

Koenig, M. A. & Kaplan, P. W., Jan 1 2019, Handbook of Clinical Neurology. Elsevier B.V., p. 89-102 14 p. (Handbook of Clinical Neurology; vol. 161).

Research output: Chapter in Book/Report/Conference proceedingChapter

Brain Death
Electroencephalography
Guidelines
Evoked Potentials
Brain Stem

Cell fate engineering tools for iPSC disease modeling

Lo, E. K. W. & Cahan, P., Jan 1 2019, Methods in Molecular Biology. Humana Press Inc., p. 427-454 28 p. (Methods in Molecular Biology; vol. 1975).

Research output: Chapter in Book/Report/Conference proceedingChapter

Cell Engineering
RNA Sequence Analysis
Health Services Needs and Demand
Lenses
Population

Chronic disease among native North Americans

Redmond, L. & Gittelsohn, J., Apr 18 2019, Routledge Handbook of Indigenous Wellbeing. Taylor and Francis, p. 23-34 12 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Chronic disease

Clinical applications of control systems models: The neural integrators for eye movements

Sadeghpour, S., Zee, D. S. & Leigh, R. J., Jan 1 2019, Progress in Brain Research. Elsevier B.V., (Progress in Brain Research).

Research output: Chapter in Book/Report/Conference proceedingChapter

Eye Movements
Pathologic Nystagmus
Neural Networks (Computer)
Systems Analysis
Noise

Clinical neurophysiology of altered states of consciousness: Encephalopathy and coma

Johnson, E. & Kaplan, P. W., Jan 1 2019, Handbook of Clinical Neurology. Elsevier B.V., p. 73-88 16 p. (Handbook of Clinical Neurology; vol. 161).

Research output: Chapter in Book/Report/Conference proceedingChapter

Persistent Vegetative State
Neurophysiology
Brain Diseases
Coma
Consciousness

Conditional mutation of SMC5 in mouse embryonic fibroblasts

Gaddipati, H., Pryzhkova, M. & Jordan, P., Jan 1 2019, Methods in Molecular Biology. Humana Press Inc., p. 35-46 12 p. (Methods in Molecular Biology; vol. 2004).

Research output: Chapter in Book/Report/Conference proceedingChapter

Eukaryota
Fibroblasts
Maintenance
Mutation
RNA Interference

Detecting Single and Multiple BDNF Transcripts by In Situ Hybridization in Neuronal Cultures and Brain Sections

Colliva, A., Maynard, K. R., Martinowich, K. & Tongiorgi, E., Jan 1 2019, Neuromethods. Humana Press Inc., p. 27-53 27 p. (Neuromethods; vol. 143).

Research output: Chapter in Book/Report/Conference proceedingChapter

Brain-Derived Neurotrophic Factor
In Situ Hybridization
Exons
Brain
Nerve Growth Factors

Emerging shifts in neuroimaging data analysis in the era of “big data”

Bzdok, D., Schulz, M. A. & Lindquist, M., Jan 1 2019, Personalized Psychiatry: Big Data Analytics in Mental Health. Springer International Publishing, 1 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Neuroimaging
Imaging techniques
Brain
Positron emission tomography
Costs and Cost Analysis

Etiology and management of upper-extremity catheter-related thrombosis in cancer patients

Rajasekhar, A. & Streiff, M. B., Jan 1 2019, Cancer Treatment and Research. Springer International Publishing, p. 117-137 21 p. (Cancer Treatment and Research; vol. 179).

Research output: Chapter in Book/Report/Conference proceedingChapter

Upper Extremity
Thrombosis
Catheters
Neoplasms
Equipment and Supplies

Eye position-dependent opsoclonus in mild traumatic brain injury

Rizzo, J. R., Hudson, T. E., Sequeira, A. J., Dai, W., Chaudhry, Y., Martone, J., Zee, D. S., Optican, L. M., Balcer, L. J., Galetta, S. L. & Rucker, J. C., Jan 1 2019, Progress in Brain Research. Elsevier B.V., (Progress in Brain Research).

Research output: Chapter in Book/Report/Conference proceedingChapter

Brain Concussion
Ocular Motility Disorders
Post-Concussion Syndrome
Saccades
Frontal Lobe

From immune checkpoints to vaccines: The past, present and future of cancer immunotherapy

Osipov, A., Murphy, A. & Zheng, L., Jan 1 2019, Advances in Cancer Research. Academic Press Inc., (Advances in Cancer Research).

Research output: Chapter in Book/Report/Conference proceedingChapter

Immunotherapy
Vaccines
Neoplasms
Immune System
Oncolytic Viruses

Insomnia Pharmacotherapies: Pharmacodynamics, Strategies, New Directions, and Key Measures in Clinical Trials

Neubauer, D., Jan 1 2019, Handbook of Behavioral Neuroscience. Elsevier B.V., p. 639-648 10 p. (Handbook of Behavioral Neuroscience; vol. 30).

Research output: Chapter in Book/Report/Conference proceedingChapter

Sleep Initiation and Maintenance Disorders
Clinical Trials
Drug Therapy
United States Food and Drug Administration
Hypnotics and Sedatives

Kidney diseases in the age of molecular diagnostics: An integrated histopathologic and molecular approach

Delsante, M., Kopp, J. B. & Rosenberg, A., Mar 20 2019, Pathological Specimens And Genomic Medicine: Emerging Issues. World Scientific Publishing Co., p. 271-306 36 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Malignant intramedullary spinal cord tumors

Shimony, N., Hartnett, S., Osburn, B., Groves, M. & Jallo, G., Jan 24 2019, Spinal Cord Tumors. Springer International Publishing, p. 337-364 28 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Spinal Cord Neoplasms

microRNAs in tissue-based diagnosis and prognosis: Possibilities and limitations

Halushka, M. K., Mar 20 2019, Pathological Specimens And Genomic Medicine: Emerging Issues. World Scientific Publishing Co., p. 217-244 28 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

miRNA as a marker for in vitro neurotoxicity testing and related neurological disorders

Smirnova, L. & Maertens, A., Jan 1 2019, Neuromethods. Humana Press Inc., p. 255-281 27 p. (Neuromethods; vol. 145).

Research output: Chapter in Book/Report/Conference proceedingChapter

Nervous System Diseases
MicroRNAs
Testing
Brain
Toxicity

Mitochondrial dysfunction in HIV-induced peripheral neuropathy

Roda, R. & Hoke, A., Jan 1 2019, International Review of Neurobiology. Academic Press Inc., (International Review of Neurobiology).

Research output: Chapter in Book/Report/Conference proceedingChapter

Peripheral Nervous System Diseases
HIV Infections
Mitochondria
Homeostasis
HIV

Nucleic acid extraction from human biological samples

Mullegama, S. V., Alberti, M. O., Au, C., Li, Y., Toy, T., Tomasian, V. & Xian, R., Jan 1 2019, Methods in Molecular Biology. Humana Press Inc., p. 359-383 25 p. (Methods in Molecular Biology; vol. 1897).

Research output: Chapter in Book/Report/Conference proceedingChapter

Nucleic Acids
RNA
Nucleoproteins
Clinical Pathology
DNA

Overview of BCL-2 Family Proteins and Therapeutic Potentials

Huska, J. D., Lamb, H. M. & Hardwick, J. M., Jan 1 2019, Methods in Molecular Biology. Humana Press Inc., p. 1-21 21 p. (Methods in Molecular Biology; vol. 1877).

Research output: Chapter in Book/Report/Conference proceedingChapter

Amino Acid Motifs
Proteins
Amino Acid Sequence
Cell Death
Therapeutics

Pericytes in Sarcomas and Other Mesenchymal Tumors

Chang, L., Scott, M. A., Meyers, C. A. & James, A., Jan 1 2019, Advances in Experimental Medicine and Biology. Springer New York LLC, p. 109-124 16 p. (Advances in Experimental Medicine and Biology; vol. 1147).

Research output: Chapter in Book/Report/Conference proceedingChapter

Pericytes
Sarcoma
Tumors
Neoplasms
Myofibroma

Preparation of filamentous proteins for electron microscopy visualization and reconstruction

Matyszewski, M. & Sohn, J., Jan 1 2019, Methods in Enzymology. Academic Press Inc., (Methods in Enzymology).

Research output: Chapter in Book/Report/Conference proceedingChapter

Cryoelectron Microscopy
Electron microscopy
Electron Microscopy
Visualization
Inflammasomes

Protein Microarrays and Liposome: A Method for Studying Lipid–Protein Interactions

Herianto, S., Chen, C. S. & Zhu, H., Jan 1 2019, Methods in Molecular Biology. Humana Press Inc., p. 191-199 9 p. (Methods in Molecular Biology; vol. 2003).

Research output: Chapter in Book/Report/Conference proceedingChapter

Protein Array Analysis
Liposomes
Lipids
Proteins
Phospholipids

Quantifying tissue-specific overexpression of FOXO in Drosophila via mRNA fluorescence in situ hybridization using branched DNA probe technology

Blice-Baum, A. C., Vogler, G., Viswanathan, M. C., Trinh, B., Limpitikul, W. B. & Cammarato, A. R., Jan 1 2019, Methods in Molecular Biology. Humana Press Inc., p. 171-190 20 p. (Methods in Molecular Biology; vol. 1890).

Research output: Chapter in Book/Report/Conference proceedingChapter

DNA Probes
Fluorescence In Situ Hybridization
Drosophila
Technology
Messenger RNA

Rare spinal cord tumors

Shimony, N., Osburn, B., Hartnett, S., Groves, M. & Jallo, G., Jan 24 2019, Spinal Cord Tumors. Springer International Publishing, p. 397-431 35 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Spinal Cord Neoplasms

Rebound nystagmus, a window into the oculomotor integrator

Otero-Millan, J., Colpak, A. I., Kheradmand, A. & Zee, D. S., Jan 1 2019, Progress in Brain Research. Elsevier B.V., (Progress in Brain Research).

Research output: Chapter in Book/Report/Conference proceedingChapter

Pathologic Nystagmus
Proprioception
Healthy Volunteers

Semisynthesis of ubiquitinated histone H2B with a native or nonhydrolyzable linkage

Morgan, M., Jbara, M., Brik, A. & Wolberger, C., Jan 1 2019, Methods in Enzymology. Academic Press Inc., p. 1-27 27 p. (Methods in Enzymology; vol. 618).

Research output: Chapter in Book/Report/Conference proceedingChapter

Histones
Ubiquitin
Nucleosomes
Lysine
Inteins

Severe neonatal manifestations of infantile liver failure syndrome type 1 caused by cytosolic leucine-tRNA synthetase deficiency

Peroutka, C., Salas, J., Britton, J., Bishop, J., Kratz, L., Gilmore, M., Fahrner, J. A., Golden, W. C. & Wang, T., Jan 1 2019, JIMD Reports. Springer, p. 71-76 6 p. (JIMD Reports; vol. 45).

Research output: Chapter in Book/Report/Conference proceedingChapter

Leucine-tRNA Ligase
Liver Failure
Liver
Failure to Thrive
Anemia

Spatial orientation: Model-based approach to multi-sensory mechanisms

Kheradmand, A. & Otero-Millan, J., Jan 1 2019, Progress in Brain Research. Elsevier B.V., (Progress in Brain Research).

Research output: Chapter in Book/Report/Conference proceedingChapter

Head
Brain

Standardized method for the study of antibody neutralization of HCV pseudoparticles (HCVpp)

Bailey, J., Urbanowicz, R. A., Ball, J. K., Law, M. & Foung, S. K. H., Jan 1 2019, Methods in Molecular Biology. Humana Press Inc., p. 441-450 10 p. (Methods in Molecular Biology; vol. 1911).

Research output: Chapter in Book/Report/Conference proceedingChapter

Hepatitis C Antibodies
Hepacivirus
Hepatocellular Carcinoma
Virus Internalization
Product Packaging

Studying MHC class II peptide loading and editing in vitro

Kim, A. R., Ishizuka, I. E., Hartman, I. Z., Poluektov, Y., Narayan, K. & Sadegh-Nasseri, S., Jan 1 2019, Methods in Molecular Biology. Humana Press Inc., p. 343-355 13 p. (Methods in Molecular Biology; vol. 1988).

Research output: Chapter in Book/Report/Conference proceedingChapter

Peptides
Immunodominant Epitopes
Surface Plasmon Resonance
HLA-DR Antigens
Tryptophan

Surgical methods for inner ear gene delivery in neonatal mouse

Isgrig, K. & Chien, W. W., Jan 1 2019, Methods in Molecular Biology. Humana Press Inc., p. 221-226 6 p. (Methods in Molecular Biology; vol. 1937).

Research output: Chapter in Book/Report/Conference proceedingChapter

Inner Ear
Genetic Therapy
Genes
Ear Round Window
Semicircular Canals

Therapeutic strategies to block the hypoxic response

DiGiacomo, J. W. & Gilkes, D., Jan 1 2019, Advances in Experimental Medicine and Biology. Springer New York LLC, p. 141-157 17 p. (Advances in Experimental Medicine and Biology; vol. 1136).

Research output: Chapter in Book/Report/Conference proceedingChapter

Prodrugs
Dimerization
DNA
Cytotoxins
Biomarkers

Tracking DNA sensor and inflammasome complexes in cells using confocal microscopy

Antiochos, B., Jan 1 2019, Methods in Enzymology. Academic Press Inc., (Methods in Enzymology).

Research output: Chapter in Book/Report/Conference proceedingChapter

Inflammasomes
Pattern Recognition Receptors
Confocal microscopy
Fluorescence Microscopy
Confocal Microscopy

Tracking the polymerization of DNA sensors and inflammasomes using FRET

Mazanek, Z. & Sohn, J., Jan 1 2019, Methods in Enzymology. Academic Press Inc., (Methods in Enzymology).

Research output: Chapter in Book/Report/Conference proceedingChapter

Inflammasomes
Thermodynamics
Polymerization
Costs and Cost Analysis
DNA
2018

3D-printing composite polycaprolactone-decellularized bone matrix scaffolds for bone tissue engineering applications

Rindone, A. N., Nyberg, E. & Grayson, W. L., Jan 1 2018, Methods in Molecular Biology. Humana Press Inc., p. 209-226 18 p. (Methods in Molecular Biology; vol. 1577).

Research output: Chapter in Book/Report/Conference proceedingChapter

Bone Matrix
Tissue Engineering
Bone and Bones
Transplants
Stem Cells

49 - Genetics and Pathophysiology of Cystic Fibrosis

Cutting, G. R., Engelhardt, J. & Zeitlin, P. L., Mar 8 2018, Kendig's Disorders of the Respiratory Tract in Children. Elsevier Inc., p. 757-768.e6

Research output: Chapter in Book/Report/Conference proceedingChapter

Cystic Fibrosis
Mucociliary Clearance
Precision Medicine
Pancreatitis
Chronic Obstructive Pulmonary Disease

57 - Lung Diseases Associated With Disruption of Pulmonary Surfactant Homeostasis

Nogee, L. & Trapnell, B. C., Mar 8 2018, Kendig's Disorders of the Respiratory Tract in Children. Elsevier Inc., p. 836-849.e5

Research output: Chapter in Book/Report/Conference proceedingChapter

Pulmonary Surfactants
Lung Diseases
Homeostasis
Complex Mixtures
Surface-Active Agents

Acquired aplastic anemia

Dezern, A. & Brodsky, R. A., Nov 19 2018, Wintrobe's Clinical Hematology: Fourteenth Edition. Wolters Kluwer Health Pharma Solutions (Europe) Ltd, p. 2968-3003 36 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Aplastic Anemia

Almost everything you do is a habit

Haith, A., Apr 24 2018, Think Tank: Forty Neuroscientists Explore the Biological Roots of Human Experience. Yale University Press, p. 177-182 6 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Habits

Anesthesia and analgesia for shoulder and elbow surgery

Bravos, E., Jan 1 2018, Othopaedic Knowledge Update: Shoulder and Elbow. Wolters Kluwer Health, p. 623-632 10 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Anesthesia and Analgesia
Elbow

Anterior cervical arthrodesis in children

Menga, E. N., Ain, M. & Sponseller, P. D., Jan 1 2018, The Management of Disorders of the Child's Cervical Spine. Springer US, p. 275-284 10 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Arthrodesis
Spine
Bone and Bones
Transplants
Diskectomy

Antibody specificity profiling using protein microarrays

Ramos-López, P., Irizarry, J., Pino, I. & Blackshaw, S., Jan 1 2018, Methods in Molecular Biology. Humana Press Inc., p. 223-229 7 p. (Methods in Molecular Biology; vol. 1785).

Research output: Chapter in Book/Report/Conference proceedingChapter

Protein Array Analysis
Antibody Specificity
Antibodies
Antigens
Proteins