Howard Hughes Medical Institution

Fingerprint The fingerprint is based on mining the text of the scientific documents related to the associated persons. Based on that an index of weighted terms is created, which defines the key subjects of research unit

Semaphorins Medicine & Life Sciences
Ribosomes Medicine & Life Sciences
Transposases Medicine & Life Sciences
Proteins Medicine & Life Sciences
Retina Medicine & Life Sciences
Genes Medicine & Life Sciences
Transfer RNA Medicine & Life Sciences
Rhodopsin Medicine & Life Sciences

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Research Output 1988 2019

Beta-catenin signaling regulates barrier-specific gene expression in circumventricular organ and ocular vasculatures

Wang, Y., Sabbagh, M. F., Gu, X., Rattner, A., Williams, J. & Nathans, J., Apr 1 2019, In : eLife. 8

Research output: Contribution to journalArticle

Open Access
beta Catenin
Capillary Permeability
Gene expression
Brain
Endothelial cells

Dlg1 activates beta-catenin signaling to regulate retinal angiogenesis and the blood-retina and blood-brain barriers

Cho, C., Wang, Y., Smallwood, P. M., Williams, J. & Nathans, J., May 8 2019, In : eLife. 8

Research output: Contribution to journalArticle

Open Access
beta Catenin
Blood-Brain Barrier
Retina
Blood
Guanylate Kinases

Hypoxia tolerance in the Norrin-deficient retina and the chronically hypoxic brain studied at single-cell resolution

Heng, J. S., Rattner, A., Stein-O’Brien, G. L., Winer, B. L., Jones, B. W., Vernon, H. J., Goff, L. & Nathans, J., Apr 30 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 18, p. 9103-9114 12 p.

Research output: Contribution to journalArticle

Retina
Neuroglia
Brain
RNA Sequence Analysis
Transcriptome